Abstract:
A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.
Abstract:
A medicament respiratory delivery device including a housing having a chamber, an inlet and an outlet generally coaxially aligned with the chamber, wherein the chamber includes a medicament cartridge having a body including a generally cylindrical passage extending through the opposed ends of the cartridge generally coaxially aligned with the inlet and outlet of the housing having thin burstable polyolefin membranes having a burst pressure of between 1.2 and 10 atmospheres stretched taut over the ends of the cartridge, such that fluid delivered to the inlet ruptures the membranes, entraining medicament contained within the cartridge passage which is delivered to the patient's respiratory system through the outlet. The method of forming the cartridge includes stretching out and bending a membrane to one end of the cartridge, preferably by heat bonding, filling the cartridge with a medicament and sealing the opposed end preferably with a second burstable membrane by stretching out a membrane over a convex surface and heat bonding.
Abstract:
A product container having a valve stem is coupled to the first of two flow passages in a coupler-aspirator. The flow passages join at a nozzle. The second flow passage communicates with a first chamber. A guide fits over and extends above the product container and has ridges on the interior thereof. Notched winged portions of the coupler-aspirator are retained on the ridges. A cylinder having a second chamber is coupled to the coupleraspirator and positioned therebetween is a flexible annular gasket. A hollow valve stem having radial openings is mounted for movement within the chambers. The inner periphery of the gasket obturates the radial openings. A piston slides within the cylinder. Integral with the piston is an actuating member, and integral with the actuating member is a downwardly extending flange concentric around the piston. The bottom of the flange is beveled to mate with the beveled upper edges of the winged portions of the coupler-aspirator.
Abstract:
A pump dispenser is arranged for dispensing solidous material under a manually-developed pressure, with the dispenser being capable of pumping and mechanically agitating the solidous material in a storage container. The resultant dispensed solidous fluid is provided with more consistent suspended solid concentrations with greater solid particle distribution homogeneity.
Abstract:
An on-demand fluid dispenser (30) to dispense fluid (63) in response to gas generation by a gas cell (48). The on-demand fluid dispenser (30) includes an expandable gas chamber (51), a fluid chamber (57), and an on-demand gas cell (48). The expandable gas chamber (51) includes a moveable plunger forming a wall of the expandable gas chamber. The moveable plunger also forms a wall (54) of the fluid chamber (57). The on-demand gas cell (48) is configured to generate the gas on demand. The on-demand gas cell (48) is also configured to direct the gas to the expandable gas chamber (51) to expand the expandable gas chamber (51). Expansion of the expandable gas chamber (51) moves the moveable plunger (54) to reduce a volume of the fluid chamber (57) and to dispense an amount of fluid (63) from the fluid chamber (57).
Abstract:
A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament respiratory delivery device of this invention may be utilized to deliver a controlled unit dose of an aerosolizable medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.
Abstract:
A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive t the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.
Abstract:
Powder jet dispenser for medicament inhalation therapies, intended to be the drug pack container, incorporating a dose metering system, comprising turning filling means (27, 28, 29, 30, 31, 35) and a separation unit (25, 26) to fill a fix positioned dosage chamber (19) and to provide, after its filling, an air-tight separation from the medicament reservoir (36). Said dosage chamber (19) being connected to a compression chamber (5) part of a servo-assisted air compression system actuated by a manual stroke of a plunger (3) providing the compression of a spiral load spring (7), and then its release by means of a sliding control mechanism (11, 14) automatically actuated by the continuation of the stroke on the plunger (3). Said spring (7) bearing against a piston (8) which, therefore, snaps forward into said compression chamber (5) producing a jet of compressed air which reaches the dosage chamber (19), and takes the drug out to the user's mouth through a nozzle (20) provided with a check valve (22) to avoid the entrance of outside air.
Abstract:
본 발명은 펌프용기 내부에 공기를 주입하여 압력을 유도하고 이를 내용물 토출 작동 시에 이용하여, 펌프용기 내부에 잔류하는 내용물의 펌프에 의한 토출 효율을 좋게 하고, 펌프용기의 내용물을 완전 소진하도록 하여 버려지는 내용물의 낭비를 줄일 수 있도록 한 펌프용기 및 펌프장치에 관한 것이다. 본 발명은 용기본체에 공기압을 불어 넣기 위한 분리된 2중 배출수단을 갖는 이중펌프와, 이중펌프와 연결되도록 설치되는 내용물 배출호스를 따라 수직 하강하며 용기본체의 내측면에 남아 있는 내용물을 끌어 내리도록 설치되는 잔류물 제거수단을 포함하여 이루어지는 것을 특징으로 하는 펌프용기 및 펌프장치를 개시한다.