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    APPARATUS AND METHOD FOR IRRADIATING A SCATTERING MEDIUM
    61.
    发明申请
    APPARATUS AND METHOD FOR IRRADIATING A SCATTERING MEDIUM 有权
    辐射散射介质的装置和方法

    公开(公告)号：US20120182591A1

    公开(公告)日：2012-07-19

    申请号：US13328255

    申请日：2011-12-16

    Applicant: Takahiro Masumura

    Inventor： Takahiro Masumura

    IPC: G03H1/12 ,  G02B26/00

    CPC classification number: G03H1/0443 ,  G01N21/00 ,  G01N21/4795 ,  G01N21/6456 ,  G01N2201/0675 ,  G02B21/0032 ,  G02B21/0052 ,  G02B21/0056 ,  G02B26/06 ,  G03H2001/0072 ,  G03H2001/0083 ,  G03H2001/0447 ,  G03H2001/0458 ,  G03H2001/0467

    Abstract: An apparatus includes a low-coherent light source configured to emit an electromagnetic wave; a spatial light modulator configured to modulate a wavefront of the electromagnetic wave; an interferometer including a movable mirror to set a depth of a medium to be irradiated by the electromagnetic wave and a beam splitter configured to the electromagnetic wave into a reference beam and an object beam; a detector to detect information about an interference pattern formed by the object beam coming from the medium via the beam splitter and the reference beam reflected by the movable mirror; and a controller configured to control the spatial light modulator, based on the information, to form a modulated wavefront for irradiating the medium.

    Abstract translation: 一种装置，包括配置成发射电磁波的低相干光源; 配置为调制所述电磁波的波前的空间光调制器; 干涉仪，包括可移动反射镜，用于设置要被电磁波照射的介质的深度;以及分配器，被配置为电磁波到参考光束和物体光束中; 检测器，用于检测由通过分束器的来自介质的物体束形成的干涉图案和由可移动镜反射的参考光束的信息; 以及控制器，其被配置为基于所述信息来控制所述空间光调制器，以形成用于照射所述介质的调制波阵面。

    MEMS Microdisplay Optical Imaging and Sensor Systems for Underwater Scattering Environments
    62.
    发明申请
    MEMS Microdisplay Optical Imaging and Sensor Systems for Underwater Scattering Environments 有权
    用于水下散射环境的MEMS微显示器光学成像和传感器系统

    公开(公告)号：US20120069342A1

    公开(公告)日：2012-03-22

    申请号：US13089715

    申请日：2011-04-19

    Applicant: Fraser Dalgleish ,  Anni Dalgleish ,  Bing Ouyang

    Inventor： Fraser Dalgleish ,  Anni Dalgleish ,  Bing Ouyang

    IPC: G01N21/55 ,  H01L27/00

    CPC classification number: G01N21/47 ,  G01N2021/1793 ,  G01N2201/0675

    Abstract: An imaging or sensor system comprises a transmitter assembly, a receiver assembly and a control unit. The transmitter assembly defines an outgoing optical beam transmission path with respect to a target surface and the receiver assembly defines a return optical signal transmission path from the target surface. Each of the paths includes transmission through or reflection from at least one microdisplay device comprising a plurality of controllable elements for selective placement in a transmit mode for transmission of light along the transmission paths. A control unit selectively places the microdisplay device elements in the transmission mode.

    Abstract translation: 成像或传感器系统包括发射器组件，接收器组件和控制单元。 发射器组件相对于目标表面限定出射光束传输路径，并且接收器组件限定了来自目标表面的返回光信号传输路径。 每个路径包括从包括多个可控元件的至少一个微显示设备的透射或反射，用于以发射模式选择性地放置以沿着传输路径传输光。 控制单元选择性地将微显示器件元件置于传输模式中。

    OPTICAL PLATFORM FOR SIMULTANEOUSLY STIMULATING, MANIPULATING, AND PROBING MULTIPLE LIVING CELLS IN COMPLEX BIOLOGICAL SYSTEMS
    63.
    发明申请
    OPTICAL PLATFORM FOR SIMULTANEOUSLY STIMULATING, MANIPULATING, AND PROBING MULTIPLE LIVING CELLS IN COMPLEX BIOLOGICAL SYSTEMS 审中-公开
    用于同时刺激，操纵和探索复杂生物系统中多种生命细胞的光学平台

    公开(公告)号：US20100292931A1

    公开(公告)日：2010-11-18

    申请号：US12774856

    申请日：2010-05-06

    Applicant: Sheng Wang ,  Cheng Sun ,  Xiang Zhang

    Inventor： Sheng Wang ,  Cheng Sun ,  Xiang Zhang

    IPC: G06F19/00 ,  G01N21/00

    CPC classification number: G01N21/6458 ,  G01N21/6408 ,  G01N2201/0627 ,  G01N2201/0675

    Abstract: An optical platform and system for the simultaneous stimulation, manipulation and probing of multiple living cells in complex biological systems. The apparatus utilizes a spatiotemporal light modulator to expose a sample to pinpoints of light at selected times and wavelengths in two or three dimensional space and then detect the responses. In one embodiment, a spatiotemporal light modulator is optically coupled to a variable wavelength light source, a lens system and a system control unit with sample response sensors, wherein sample responses are detected after exposure to patterns of light in real time. Light patterns can be modulated in response to sample responses.

    Abstract translation: 用于在复杂生物系统中同时刺激，操纵和探测多个活细胞的光学平台和系统。 该装置利用时空光调制器将样品暴露于两维或三维空间中选定时间和波长处的光的精确点，然后检测响应。 在一个实施例中，时空光调制器与可变波长光源，透镜系统和具有采样响应传感器的系统控制单元光学耦合，其中在曝光到实际图案之后检测样本响应。 光图案可以响应于样品响应进行调制。

    METHOD OF FLUORESCENCE IMAGING
    64.
    发明申请
    METHOD OF FLUORESCENCE IMAGING 有权
    荧光成像方法

    公开(公告)号：US20100278399A1

    公开(公告)日：2010-11-04

    申请号：US12601587

    申请日：2008-05-30

    Applicant: Artur Bednarkiewicz ,  Maurice Whelan

    Inventor： Artur Bednarkiewicz ,  Maurice Whelan

    IPC: G06K9/00

    CPC classification number: G01N21/6408 ,  G01N21/6458 ,  G01N2021/6423 ,  G01N2201/0675 ,  G02B21/16 ,  G02B21/365

    Abstract: Method of fluorescence imaging including: illuminating a sample to excite its fluorescence and acquiring an image thereof; based on fluorescence spectral and spatial information from the sample's fluorescence image, segmenting the image into regions of similar spectral properties; for each image segment, exciting the fluorescence of the corresponding sample region, and detecting the corresponding fluorescence; based on modelling, determining expected fluorescence parameters from the fluorescence signals detected for each region; scanning the sample and determining final fluorescence parameters based on said expected fluorescence parameters.

    Abstract translation: 荧光成像方法包括：照射样品以激发其荧光并获得其图像; 基于来自样品荧光图像的荧光光谱和空间信息，将图像分割成具有相似光谱性质的区域; 对于每个图像片段，激发相应样品区域的荧光，并检测相应的荧光; 基于建模，从为每个区域检测的荧光信号确定预期的荧光参数; 扫描样品并基于所述预期荧光参数确定最终荧光参数。

    Confocal microscope, fluorescence measuring method and polarized light measuring method using cofocal microscope
    66.
    发明申请
    Confocal microscope, fluorescence measuring method and polarized light measuring method using cofocal microscope 审中-公开
    共焦显微镜，荧光测量法和偏光测量方法采用共焦显微镜

    公开(公告)号：US20060012872A1

    公开(公告)日：2006-01-19

    申请号：US10529395

    申请日：2003-09-18

    Applicant: Terutake Hayashi ,  Katsuhiro Maekawa ,  Takayuki Shibata

    Inventor： Terutake Hayashi ,  Katsuhiro Maekawa ,  Takayuki Shibata

    IPC: G02B21/06

    CPC classification number: G01N21/6458 ,  G01N21/21 ,  G01N21/6445 ,  G01N21/6452 ,  G01N2021/6471 ,  G01N2021/6478 ,  G01N2201/0675 ,  G02B21/0024 ,  G02B21/0068 ,  G02B21/0076

    Abstract: The present invention relates to a confocal microscope and the measuring methods of fluorescence and the polarized light using the same, and said confocal microscope is provided with the inlet optical part (10, 10′) to let the polarized light from an illuminating light source (11) onto an object to be observed (2) via a matrix type liquid crystal device (22) provided with a microlens array (21) on its top part, and an objective lens (23), the light detecting part (30, 30′) to detect the reflected or the fluorescent light from the object to be observed, and the liquid crystal control subpart (52) to control a liquid crystal device (22), and it transmits the light passing through said microlens array (21) from each microlens to each pixel (22a) of the liquid crystal device (22), and makes a plurality of foci (24) on the object to be observed (2) by the objective lens (23), as well as controls polarization directions of the lights transmitted through each pixel of the liquid crystal device (22) using the liquid crystal control subpart (52) so that they are made mutually orthogonal.

    Abstract translation: 本发明涉及共焦显微镜以及使用其的荧光和偏振光的测量方法，并且所述共聚焦显微镜设置有入射光学部件（10,10'），以使来自照明光源的偏振光 11）通过在其顶部设置有微透镜阵列（21）的矩阵型液晶装置（22）和物镜（23）到待观察的物体（2）上，光检测部分（30,30） '）来检测来自被观察物体的反射光或荧光，以及液晶控制部（52）来控制液晶装置（22），将通过所述微透镜阵列（21）的光从 每个微透镜到液晶装置（22）的每个像素（22a），并且通过物镜（23）在被观察物体（2）上形成多个焦点（24），并且控制偏振方向 的光线通过每个像素传输 使用液晶控制子部（52）使液晶装置（22）相互正交。

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