公开(公告)号：WO2006036768A2

公开(公告)日：2006-04-06

申请号：PCT/US2005/034091

申请日：2005-09-22

Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES ,  BECKER, David ,  LEY, James, Joseph

Inventor： BECKER, David ,  LEY, James, Joseph

IPC: C07C239/08

CPC classification number: C07D213/20 ,  C07C291/02 ,  C07C309/46 ,  C07C323/45 ,  C07C2601/14 ,  C07D207/46 ,  C07D339/08

Abstract: The present invention provides azulenyl nitrones, such as those having the following general formula: (I) compositions comprising the same and methods of their use for the treatment or prevention of oxidative, ischemic, ischemia/reperfusion-related and chemokine-mediated conditions.

Abstract translation: 本发明提供了薁基硝酮，例如具有以下通式的那些：（I）包含其的组合物及其用于治疗或预防氧化，缺血，缺血/再灌注相关和趋化因子介导的病症的方法。

公开(公告)号：WO2005094689A1

公开(公告)日：2005-10-13

申请号：PCT/IB2005/050984

申请日：2005-03-22

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  BECKER, David ,  WRAY, Terry ,  HART, Jeffrey

Inventor： BECKER, David ,  WRAY, Terry ,  HART, Jeffrey

IPC: A61B8/12

CPC classification number: A61B8/4461 ,  A61B8/12 ,  A61B8/4281 ,  A61B8/445 ,  A61B8/483

Abstract: An intracavity ultrasound probe includes a pivotally mounted array transducer which is oscillated to scan a volumetric region from within the body. The transducer is oscillated by a motor located in the probe handle. The array transducer is immersed in a liquid which acoustically couples ultrasonic energy between the elements of the transducer and the body. The acoustic coupling liquid is located in the distal tip of the probe shaft, where only 6 cc of liquid is required. The small amount of liquid reduces the weight of the shaft of the probe so that the center of gravity of the probe is in the handle, making the probe comfortable and easy to manipulate. The majority of parts in the probe shaft are made of aluminum or other low density materials, keeping the overall weight of the probe to about 250 grams.

Abstract translation: 腔内超声波探头包括枢转安装的阵列换能器，其被振荡以从体内扫描体积区域。 传感器由位于探头手柄中的电机振荡。 将阵列换能器浸入液体中，该液体在换能器的元件和身体之间声学耦合超声波能量。 声耦合液体位于探头轴的远端，其中只需要6cc液体。 少量的液体减少了探头轴的重量，使得探头的重心位于手柄中，使得探头舒适且易于操作。 探头轴中的大部分部件由铝或其他低密度材料制成，将探头的总重量保持在250克左右。