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    SENSITIVE EMISSION LIGHT GATHERING AND FLOW THROUGH DETECTION SYSTEM
    71.
    发明申请
    SENSITIVE EMISSION LIGHT GATHERING AND FLOW THROUGH DETECTION SYSTEM 审中-公开
    通过检测系统的敏感发射光通量和流量

    公开(公告)号：WO2008143725A2

    公开(公告)日：2008-11-27

    申请号：PCT/US2008/001910

    申请日：2008-02-13

    Applicant: CREATV MICROTECH, INC. ,  TANG, Cha-Mei ,  AMSTUTZ III, Platte

    Inventor： TANG, Cha-Mei ,  AMSTUTZ III, Platte

    IPC: G02B6/10

    CPC classification number: G01N21/0303 ,  G01N21/255 ,  G01N21/645

    Abstract: A luminometer is provided comprising a flow through waveguide and one or more detectors. The flow through waveguide has at least two openings and the sample is free to enter from one opening and exit from the other. The flow through waveguide can be made of material that guides emission light to a bottom end of the flow through waveguide. One or more detectors may be provided which detect the emission light coming out of the bottom of the flow through waveguide. A fluorometer/photometer is also provided that comprises a flow through waveguide, one or more excitation light sources, and one or more optical detectors. The flow through waveguide has a hollow region to hold the sample. The excitation light is introduced at an angle or perpendicular to one surface of the flow through waveguide. The flow through waveguide is made of material that can guide absorption and/or emission light to the bottom end of the flow through waveguide. There are one or more detectors that detect the emission light coming out of the bottom of the flow through waveguide.

    Abstract translation: 提供了一种发光计，其包括流过波导管和一个或多个检测器。 通过波导的流动具有至少两个开口，并且样品自由地从一个开口进入并从另一个开口排出。 通过波导的流动可以由将发射光引导到通过波导的流动的底端的材料制成。 可以提供一个或多个检测器，其检测从通过波导的流的底部出射的发射光。 还提供了一种荧光计/光度计，其包括流过波导管，一个或多个激发光源和一个或多个光学检测器。 通过波导的流动具有保持样品的中空区域。 激发光以与通过波导的流动的一个表面成一角度或垂直的方式引入。 通过波导的流动由能够将吸收和/或发射光引导到通过波导的流动的底端的材料制成。 存在一个或多个检测器，其检测从通过波导的流动的底部出来的发射光。

    SENSITIVE EMISSION LIGHT GATHERING AND DETECTION SYSTEM
    73.
    发明申请
    SENSITIVE EMISSION LIGHT GATHERING AND DETECTION SYSTEM 审中-公开
    敏感发射光学和检测系统

    公开(公告)号：WO2007041507A2

    公开(公告)日：2007-04-12

    申请号：PCT/US2006/038464

    申请日：2006-10-03

    Applicant: CREATV MICROTECH, INC. ,  TANG, Cha-Mei ,  AMSTUTZ, Platte

    Inventor： TANG, Cha-Mei ,  AMSTUTZ, Platte

    IPC: G01N1/10

    CPC classification number: G01N21/0303 ,  G01N21/255 ,  G01N21/645

    Abstract: A luminometer is provided comprising a waveguide sample holder and one or more detectors. The waveguide sample holder may include a hollow region to hold the sample. The waveguide sample holder can be made of material that guides emission light preferably to a bottom end of the waveguide sample holder. One or more detectors may be provided which detect the emission light coming out of the bottom of the waveguide sample holder. A fluorometer is also provided that comprises a waveguide sample holder, one or more excitation light sources and one or more optical detectors. The waveguide sample holder has a hollow region to hold the sample. The excitation light is introduced at an angle or perpendicular to one surface of the waveguide sample holder. The waveguide sample holder is made of material that can guide emission light to the bottom end of the waveguide sample holder. There are one or more detectors that detect the emission light coming out of the bottom of the waveguide sample holder.

    Abstract translation: 提供了包括波导样品保持器和一个或多个检测器的发光计。 波导样品保持器可以包括用于保持样品的中空区域。 波导样品保持器可以由优选地将发射光引导到波导样品保持器的底端的材料制成。 可以提供一个或多个检测器，其检测从波导样品保持器的底部出来的发射光。 还提供了一种荧光计，其包括波导样品保持器，一个或多个激发光源和一个或多个光学检测器。 波导样品保持器具有用于保持样品的中空区域。 激发光以与波导样品保持器的一个表面成一定角度或垂直的方向引入。 波导样品架由能够将发射光引导到波导样品架的底端的材料制成。 存在检测从波导样品保持器的底部出射的发射光的一个或多个检测器。

    POLYMER MICROFILTRATION DEVICES, METHODS OF MANUFACTURING THE SAME AND THE USES OF THE MICROFILTRATION DEVICES
    78.
    发明专利
    POLYMER MICROFILTRATION DEVICES, METHODS OF MANUFACTURING THE SAME AND THE USES OF THE MICROFILTRATION DEVICES 未知

    公开(公告)号：CA2856405C

    公开(公告)日：2021-05-25

    申请号：CA2856405

    申请日：2012-11-21

    Applicant: CREATV MICROTECH INC

    Inventor： TANG CHA-MEI ,  ZHANG YUNQI

    IPC: G01N1/34 ,  A61B5/00 ,  B01D61/14 ,  B01D61/18 ,  B01D67/00

    Abstract: A microfilter comprising a polymer layer formed from epoxy-based photo-definable dry film, and a plurality of apertures each extending through the polymer layer. A microfilter comprising two or more polymer layers formed from epoxy-based photo-definable dry film, and a plurality of apertures or open areas each extending through the polymer layer. A method of forming a microfilter is also disclosed. The method includes providing a first layer of epoxy-based photo-definable dry film disposed on a substrate, exposing the first layer to energy through a mask to form a pattern, defined by the mask, in the first layer of dry film, forming, from the exposed first layer of dry film, a polymer layer having a plurality of apertures extending therethrough, the plurality of apertures having a distribution defined by the pattern, and removing the polymer layer from the substrate. Unique filter holder designs and methods appropriate to hold microfilters to collect the rare cells and allow performing assays in the filter holder are provided. The invention also describes the use of the microfilter and filter holder to collect rare cells from body fluids and perform assays. Rare cells collected on the microfilter in accordance with embodiments of the present invention can be used for medical and biological research applications.

    Polymer microfiltration devices, methods of manufacturing the same and the uses of the microfiltration devices
    79.
    发明专利
    Polymer microfiltration devices, methods of manufacturing the same and the uses of the microfiltration devices 未知

    公开(公告)号：AU2019271979A1

    公开(公告)日：2019-12-19

    申请号：AU2019271979

    申请日：2019-11-27

    Applicant: CREATV MICROTECH INC

    Inventor： TANG CHA-MEI ,  ZHANG YUNQI

    IPC: B01D25/02

    Abstract: A microfilter comprising a polymer layer formed from epoxy-based photo-definable dry film, and a plurality of apertures each extending through the polymer layer. A microfilter comprising two or more polymer layers formed from epoxy-based photo-definable dry film, and a plurality of apertures or open areas each extending through the polymer layer. A method of forming a microfilter is also disclosed. The method includes providing a first layer of epoxy-based photo definable dry film disposed on a substrate, exposing the first layer to energy through a mask to form a pattern, defined by the mask, in the first layer of dry film, forming, from the exposed first layer of dry film, a polymer layer having a plurality of apertures extending therethrough, the plurality of apertures having a distribution defined by the pattern, and removing the polymer layer from the substrate. Unique filter holder designs and methods appropriate to hold microfilters to collect the rare cells and allow performing assays in the filter holder are provided. The invention also describes the use of the microfilter and filter holder to collect rare cells from body fluids and perform assays. Rare cells collected on the microfilter in accordance with embodiments of the present invention can be used for medical and biological research applications. Microfilter material Pores o O:

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