Polarographic measuring electrode device
    72.
    发明公开
    Polarographic measuring electrode device 失效
    极谱电极测量装置。

    公开(公告)号:EP0212126A2

    公开(公告)日:1987-03-04

    申请号:EP86108303.8

    申请日:1986-06-18

    Applicant: RADIOMETER A/S

    CPC classification number: G01N27/404

    Abstract: An electrochemical measuring electrode device (10) for polarographically measuring the partial pressure of oxygen in an electrolytic medium comprises a cathode (14) which is capable of reducing oxygen and defines an exposed oxygen-reducing cathode surface (20), an anode (18), which defines an exposed anode surface which is arranged relative to the exposed oxygen-reducing cathode surface so as to communicate electrolytically therewith through the electrolytic medium, and a membrane (24), which covers the exposed oxygen-reducing cathode surface and further defines an electrolyte chamber (22) in which the electrolytic medium is confined. In order to effectively promote the decomposition H 2 0 2 generated in the electrolytic medium as an oxygen reduction intermediate and thereby reduce the response time of the electrode, a stable, non-biological catalytic means is provided catalytically communicating with the H 2 0 2 . The stable, non-biological catalytic means is preferably constituted by platinum black particles which may be received by the membrane at a central region (42) thereof or alternatively be received by a support structure which may further constitute a covering of at least part of the membrane (24).
    The platinum black particles may be pressed into a foil material constituting a base material of the membrane or alternatively be applied in a suspension to the membrane whereupon the suspension is solidifyed.

    Electrochemical measuring electrode device and method for transmission of signals therefrom
    74.
    发明公开
    Electrochemical measuring electrode device and method for transmission of signals therefrom 失效
    电化学测量电极装置和用于从那里发送信号的方法。

    公开(公告)号:EP0153437A1

    公开(公告)日:1985-09-04

    申请号:EP84105779.7

    申请日:1984-05-21

    Applicant: RADIOMETER A/S

    Abstract: In an electrochemical measuring electrode device (10) comprising sensor means (12, 13 and 36) for generation of one or more measuring signals, the measuring signals are multiplexed in a first multiplexing means included in an integrated electronic circuit (23) and transmitted therefrom through a two conductor cable (37) to a cooperating measuring apparatus (50). In the measuring apparatus (50), the measuring signals are demultiplexed and displayed on a display (48). The circuit (23) is mounted on an insulating ceramic substrate (21) also supporting a temperature dependent NTC resistor (28) and a Zener diode (30) together constituting a thermostating means of the electrode device. The electronic circuit of the electrode device (10) and the heat generating Zener diode (30) are supplied with power from the measuring apparatus (50). The transmission is preferably carried out in time-division multiplexed state, so that the measuring results generated by means of the sensor means and the temperature representative signal generated by the NTC resistor (28) are transmitted within individual time intervals, while an electrical power signal for supply of the electronic circuitry of the electrode device and for supply of the Zener diode (30) is transmitted within a specific subperiod of each of the transmission time intervals.
    The gated amplifier comprises a high-gain differential DC-amplifier a storage capacitor and a switch means for conversion of the gated amplifier to a mode in which any input offset of the DC-amplifier is transmitted in a unity gain mode.

    Abstract translation: 在电化学测量电极装置(10)包括传感器装置(12,13和36),用于生成一个或多个测量信号,测量信号被复用在一个第一多路复用装置包括在上集成的电子电路(23)和反式mitted有从 通过一个两个导体电缆(37),以配合的测量装置(50)。 在测量装置(50),该测量信号被解复用,并显示在显示器(48)上。 该电路(23)被安装在到绝缘陶瓷基片(21),从而支撑与温度相关的NTC电阻(28)和齐纳二极管(30)一起构成所述电极装置的恒温装置。 该电极装置(10)和发热齐纳二极管(30)的电子电路供给与来自测量装置(50)的功率。 发送优选地在时分复用状态下进行,所以没有由传感器装置和由NTC电阻器(28)产生的温度的代表信号的装置产生的测量结果是反式个人的时间间隔内mitted,而在电功率信号 对于所述电极装置的电子电路的馈电和齐纳二极管的供给(30)是每一个传输时间间隔的一个特定的子周期内的反式mitted。 门控放大器包括一个高增益差分放大器DC存储电容器和用于选通放大器的转换为一种模式,其中的任何输入的直流放大器的偏移在一个单位增益模式反mitted一个开关装置。

    COMPOSITION AND SAMPLING RECEPTACLE METHOD FOR TREATING BLOOD WITH ANTICOAGULANT
    75.
    发明公开
    COMPOSITION AND SAMPLING RECEPTACLE METHOD FOR TREATING BLOOD WITH ANTICOAGULANT 失效
    WITH A抗凝成分除血样本容器中。

    公开(公告)号:EP0149661A1

    公开(公告)日:1985-07-31

    申请号:EP84902795.0

    申请日:1984-07-13

    Applicant: RADIOMETER A/S

    Abstract: Dans le but de contrecarrer la coagulation d'un échantillon sanguin prélevé du corps (24) d'un animal ou d'un être humain et introduit dans un réceptacle tel qu'une chambre (14) d'une seringue, un anticoagulant est ajouté à l'échantillon dans le receptacle. L'anticoagulant est capable de lier des espèces de cations dans le sang que l'on veut mesurer par la suite. Ces espèces de cations comprennent des ions hydrogène, des ions ammonium, des ions de métal alcalin tels que des ions potassium et sodium, et des ions métalliques alcalino-terreux tels que des ions magnésium et calcium. De manière à compenser les proportions des espèces de cations sélectionnées qui sont liées par l'anticoagulant, un additif contenant de telles espèces de cations est ajouté à l'échantillon de manière à obtenir sensiblement la même concentration des espèces de cations sélectionnées dans un état non lié dans l'échantillon sanguin traité avec l'anticoagulant que dans l'échantillon sanguin non traité. L'anticoagulant et l'additif sont de préférence ajoutés à l'échantillon sanguin sous forme d'une composition qui peut être déposée ou portée par un corps porteur (15) pouvant être agencé dans le réceptacle dans lequel l'échantillon sanguin est introduit. La densité de masse du corps porteur non mouillé est de préférence plus petite que le poids spécifique de l'échantillon sanguin de manière à éviter l'emprisonnement de bulles d'air dans le réceptacle. Dans son état mouillé, la densité de masse du corps porteur est également de préférence différente du poids spécifique de l'échantillon sanguin de sorte que le corps porteur (15) peut être utilisé comme organe d'agitation qui améliore le mélange de la composition anticoagulante avec l'échantillon sanguin. Le corps porteur (15) peut par exemple être constitué de papier filtre.

    A liquid sampling device
    77.
    发明公开
    A liquid sampling device 失效
    Einrichtung zur Entnahme vonFlüssigkeitsproben。

    公开(公告)号:EP0117498A1

    公开(公告)日:1984-09-05

    申请号:EP84101675.1

    申请日:1984-02-17

    Applicant: RADIOMETER A/S

    Abstract: ©7 A liquid sampling device (10), in particular intended for arterial blood sampling and blood gas analysis, is disclosed. The sampling device is provided with valve means (20, 21, 22) which in the dry state permits expulsion of gas from the sampler reservoir (18), but which automatically closes on contact with blood. The valve means comprises cooperating valve surface parts (21, 26) retained apart by a dry gas permeable material (22), which collapses on contact with a liquid, thereby moving the valve means to their closed position.

    Abstract translation: 公开了一种特别用于动脉血液取样和血液气体分析的液体取样装置(10)。 采样装置设置有阀装置(20,21,22),其在干燥状态下允许从采样器储存器(18)排出气体,但是在与血液接触时自动关闭。 阀装置包括由干燥的气体可渗透材料(22)分隔开的协同的阀表面部分(21,26),其与液体接触而塌缩,从而将阀装置移动到其关闭位置。

    A liquid sampler
    78.
    发明公开
    A liquid sampler 失效
    液体取样器

    公开(公告)号:EP0102070A3

    公开(公告)日:1984-08-22

    申请号:EP83108433

    申请日:1983-08-26

    Applicant: RADIOMETER A/S

    Inventor: Andersen, Jorgen

    Abstract: A liquid sampler which may be used for collecting samples of arterial blood is preferably in the form of a syringe. A venting passage (25, 31) is defined in the syringe piston (12) so that gas may escape through the venting passage when arterial blood flows into the cylinder space (17) under the influence of the arterial blood pressure. The venting passage is controlled by valve means (19,21), which automatically close the venting passage when the cylinder space has been filled with blood and the blood starts flowing into the venting passage. The venting passage is closed by liquid resistant valve surface parts, and movement of these surface parts to their closing position is caused by a liquid reacting substance (22) which is exposed to the liquid sample flowing into the venting passage. This liquid reacting substance may, for example, be a material which swells, expands, or is softened when contacted by liquid. Alternatively, the liquid reacting substance may be a liquid soluble material.

    Abstract translation: 可用于收集动脉血样品的液体取样器优选为注射器的形式。 在注射器活塞(12)中限定通气通道(25,31),使得当动脉血液在动脉血压的影响下流入气缸空间(17)时,气体可以通过排气通道逸出。 排气通道由阀装置(19,21)控制,当气瓶空间已经充满血液并且血液开始流入通气通道时,阀装置(19,21)自动关闭通气通道。 通气通道由液体阻止的阀表面部分封闭,并且这些表面部分移动到其关闭位置是由暴露于流入通气通道的液体样品的液体反应物质(22)引起的。 这种液体反应物质可以是例如当与液体接触时膨胀,膨胀或软化的材料。 或者,液体反应物质可以是液体可溶物质。

    A syringe for collecting a blood sample
    79.
    发明公开
    A syringe for collecting a blood sample 失效
    Spritze zur Blutentnahme。

    公开(公告)号:EP0102073A2

    公开(公告)日:1984-03-07

    申请号:EP83108442.1

    申请日:1983-08-26

    Applicant: RADIOMETER A/S

    Inventor: Andersen, Jorgen

    Abstract: @ A syringe for collecting blood samples, especially arterial blood samples, comprises a syringe cylinder (11) and a piston assembly (12) displaceably arranged therein. The piston assembly defines a venting passage (25, 37, 31) through which gas or air may escape when arterial blood flows into the cylinder space (17) under the influence of the arterial blood pressure. The venting passage is controlled by valve means (23, 31), which may selectively and reversably be opened and closed independently of axial displacement of the piston assembly.
    The valve means may, for example, be operated by rotating a piston rod through a predetermined angle or by means of a valve actuating lever (35), which is biased towards a position in which the valve means are closed, and which may be tilted to an open position by depressing a finger grip (36) positioned at the free outer end of the piston rod (32).

    Abstract translation: 用于收集血液样本,特别是动脉血液样本的注射器包括注射器筒(11)和可移置地布置在其中的活塞组件(12)。 活塞组件限定通气通道(25,37,31),当动脉血液在动脉血压的影响下流动到气缸空间(17)时,气体或空气可通过该排气通道逃逸。 排气通道由阀门装置(23,31)控制,可独立于活塞组件的轴向位移选择性地和可逆地打开和关闭排气通道。 阀装置可以例如通过使活塞杆旋转预定角度或通过阀致动杆(35)来操作,所述阀致动杆(35)被偏压到阀装置关闭的位置,并且其可以倾斜 通过按压位于活塞杆(32)的自由外端的手指(36)到打开位置。

    Salt bridge liquid for the potentiometric analysis of blood
    80.
    发明公开
    Salt bridge liquid for the potentiometric analysis of blood 失效
    Salzbrückenflüssigkeitfürdie potentiometrische Blutanalyse。

    公开(公告)号:EP0094677A1

    公开(公告)日:1983-11-23

    申请号:EP83104860.8

    申请日:1983-05-17

    Applicant: RADIOMETER A/S

    CPC classification number: G01N27/401 C07C53/06 G01N33/49

    Abstract: The salt bridge liquid contains Na + -ions and HCOO--ions in substantially equimolar amounts, preferably in a concentration larger than or equal to 1 M, in particular about 4M.
    When this salt bridge liquid is used, the potentiometric measurement will give corresponding results when measuring a blood sample and the corresponding plasma sample because the suspension effect which is caused by the erythrocytes and which is seen when using other salt bridge liquids is substantially eliminated. Furthermore, different blood samples with the same ion concentration but with varying erythrocyte content will give corresponding measuring results.

    Abstract translation: 盐桥液体含有基本上等摩尔量的Na +离子和HCOO - 离子,优选浓度大于或等于1M,特别是约4M。 ...当使用这种盐桥液体时,电位测量将在测量血液样品和相应的血浆样品时产生相应的结果,因为由红细胞引起的悬浮效应,当使用其他盐桥液体时会发现 基本消除。 此外,具有相同离子浓度但具有不同红细胞含量的不同血液样品将产生相应的测量结果。

Patent Agency Ranking