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公开(公告)号：WO1997000643A1
公开(公告)日：1997-01-09
申请号：PCT/US1996010738
申请日：1996-06-20
IPC: A61B05/103
CPC classification number: A61B5/4504
Abstract: The present invention provides an apparatus for non-invasive determination of bone mass, said apparatus having a platform for supporting a bone to be measured, a spring having a selected stiffness which connects the platform to a sensor capable of measuring vibration velocity and force, and a vibrating means connected to the sensor, wherein the vibrating means exposes the sensor, the spring and the platform to vibration so that vibration velocity and force can be measured by the sensor and the mass of the bone determined. A second apparatus for non-invasive determination of bone mass having a gripping means, a spring having a selected stiffness which connects the gripping means to a platform for positioning of a bone, a sensor capable of measuring vibration velocity and force which connects the platform to a vibrating means, and a vibrating means which vibrates the sensor, the platform, the spring, and the gripping means so the vibration velocity and force can be measured by the sensor is also provided. In addition, a method of non-invasively determining mass of a bone with these apparatuses is provided.
Abstract translation: 本发明提供了一种用于非侵入式确定骨量的装置，所述装置具有用于支撑待测骨骼的平台，具有将平台连接到能够测量振动速度和力的传感器的选定刚度的弹簧，以及 连接到所述传感器的振动装置，其中所述振动装置将所述传感器，所述弹簧和所述平台暴露于振动，从而可以通过所述传感器和所确定的骨的质量来测量振动速度和力。 用于非侵入式确定具有夹持装置的骨块的第二装置，具有将夹持装置连接到用于定位骨骼的平台的选定刚度的弹簧，能够测量将平台连接到的平台的振动速度和力的传感器 振动装置和振动装置，其使传感器，平台，弹簧和夹持装置振动，从而可以通过传感器测量振动速度和力。 此外，提供了一种使用这些装置非侵入性地确定骨质量的方法。
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公开(公告)号：WO2023064772A1
公开(公告)日：2023-04-20
申请号：PCT/US2022/077911
申请日：2022-10-11
Inventor： SARKAR, Dibyendu , NA NAGARA, Viravid , DATTA, Rupali
Abstract: A green-engineered mulch product and methods for making same are disclosed. The mulch product includes a coating of aluminum-based water treatment residuals which makes the product "green." Furthermore, coating aluminum-based water treatment residuals on mulch eliminates the problem of the low hydraulic conductivity of aluminum-based water treatment presiduals and makes it feasible to utilize its pollutant removal potential without requiring any modification to existing best management practices or additional maintenance.
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73.发明申请
公开(公告)号：WO2023060199A1
公开(公告)日：2023-04-13
申请号：PCT/US2022/077701
申请日：2022-10-06
Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
Inventor： KIM, Jinho , VUNJAK-NOVAKOVIC, Gordana , O'NEILL, John, D. , PINEZICH, Meghan , MIR, Seyed, Mohammad
IPC: A61B17/22
Abstract: A method of treating tissue, the method comprising: applying a biochemical agent to a surface of a target tissue, and pulsing low intensity focused acoustic waves from an acoustic energy source toward the target tissue, such that the low intensity focused acoustic waves are pulsed at a frequency and amplitude that does not induce boiling or cavitation of the target tissue, thereby selectively removing cells of the target tissue by the low intensity acoustic waves, while leaving healthy cells of the target tissue substantially intact.
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74.发明申请
公开(公告)号：WO2021248089A1
公开(公告)日：2021-12-09
申请号：PCT/US2021/036034
申请日：2021-06-04
Inventor： YANG, Eui-Hyeok , FU, Shichen , KANG, Kyungnam
IPC: H01L43/08 , C23C16/30 , H01L43/10 , H01L43/12 , C23C16/0272 , C23C16/405 , C23C16/56
Abstract: A method for producing doped, van der Walls ferromagnetic materials is disclosed. Such materials can take the form of monolayer iron-doped transition metal dichalcogenides. Such materials are useful for the manufacture of semiconductors, as high curie temperatures are achieved (i.e., those exceeding room temperature), which allows for the preservation of useful ferromagnetic and semiconducting properties across a wider range of conditions.
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公开(公告)号：WO2021242475A2
公开(公告)日：2021-12-02
申请号：PCT/US2021/030329
申请日：2021-04-30
Inventor： CHOI, Chang-Hwan , LEE, Junghoon
Abstract: A method for creating oil-filled porous anodic oxide coatings for metallic surfaces is disclosed. The coating has anti-corrosion and omniphobic properties to resist both underwater and atmospheric conditions. To realize oil-impregnated three-dimensional bottle-shaped pores in the oxide layer in anodizing aluminum, the following steps may be taken. First, the target surface may be cleaned and electropolished. Then, a first anodizing step at a lower voltage is applied to create relatively small-diameter pores in the entrance (i.e., top) region of the oxide layer, followed by a second anodizing step at a higher voltage to subsequently create larger- diameter pores in the base (i.e., bottom) region of the oxide layer. Pore widening follows to enlarge the overall pore diameters. To fill the porous coating with an oil, a solvent exchange method may be utilized.
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Patent Agency Ranking
公开(公告)号：WO2021216777A1
公开(公告)日：2021-10-28
申请号：PCT/US2021/028487
申请日：2021-04-21
Inventor： PALIWAL, Sunil , CORNWELL, Stephen , SABIO, Michael , LOTFALIANSAREMI, Sajedeh , CASILLAS, Candice , WINDSOR, William , TOLIAS, Peter
IPC: A61P35/00 , C07D495/04 , A61K31/407 , A61K31/4439
Abstract: Compounds useful in the treatment of various cancers and in inhibiting ERK protein forms are represented by Formula 1: (I) In Formula 1, R1 is hydrogen or methyl. R2 is hydrogen, an unsubstituted alkyl group, a haloalkyl group, a hydroxy-methyl group, or a halogen substituted hydroxy-methyl group. R3 is a substituted or unsubstituted tert-butyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group. Each R4 is independently a halogen, an unsubstituted alkyl group, a haloalkyl group, an unsubstituted alkoxy group, or a haloalkoxy group. And n is 0 to 9.
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公开(公告)号：WO2021202697A1
公开(公告)日：2021-10-07
申请号：PCT/US2021/025131
申请日：2021-03-31
Applicant: GEORGIA TECH RESEARCH CORPORATION , THE TRUSTEES OF STEVENS INSTITUTE OF TECHNOLOGY , MEINHOLD, Waiman , KURT, Mehmet , OZKAYA, Efe , UEDA, Jun
Inventor： MEINHOLD, Waiman , KURT, Mehmet , OZKAYA, Efe , UEDA, Jun
Abstract: An exemplary robotic system and control method is disclosed that employs magnetic-resonance imaging (MRI) guided visual-servo positioning of a medical robot system. In an example, an MR Elastography (MRE) actuator system is disclosed that employs the exemplary MRI-guided visual servoing to assess tissues based on its mechanical properties. The exemplary MRI-guided positioning is directly and solely used as a feedback sensor through its visual output to control multiple degrees of movement of the MRE actuators. The exemplary MRI-guided positioning may be employed in various diagnostics, minimally invasive surgery, or medical procedures for any number of a medical instrument and interventional procedures that can be conducted in an MRI environment or in proximity to an MRI scanner.
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公开(公告)号：WO2021077021A1
公开(公告)日：2021-04-22
申请号：PCT/US2020/056160
申请日：2020-10-16
Inventor： HUANG, Yuping , NGUYEN, Lac Thi Thanh
Abstract: The present invention relates to methods for secure computation and/or communication. Entangled photons (118) are generated such that each participating party receives a series of optical pulses. Each party has private information (110, 112) which are never transmitted through public or private communication channels. Instead, each party converts their respective private information (110, 112) into measurement bases via an encryption process (114, 116) which are then applied to the entangled photons (118). After the measurement process, e.g., quantum frequency conversion (122, 124), reference indices are announced (124, 126) so that computation can be performed (128) without revealing the private information directly or indirectly.
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79.发明申请
公开(公告)号：WO2021026373A1
公开(公告)日：2021-02-11
申请号：PCT/US2020/045242
申请日：2020-08-06
Applicant: HACKENSACK MERIDIAN HEALTH CENTER FOR DISCOVERY AND INNOVATION , THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
Inventor： LEE, Woo , CHEN, Zhehuan , ZILBERBERG, Jenny
Abstract: The described invention provides an ex vivo dynamic multiple myeloma (MM) cancer niche contained in a pumpless perfusion culture device. The dynamic MM cancer niche includes (a) a three-dimensional tissue construct containing a dynamic ex vivo bone marrow (BM) niche, which contains a mineralized bone-like tissue containing viable osteoblasts self- organized into cohesive multiple cell layers and an extracellular matrix secreted by the viable adherent osteoblasts; and a microenvironment dynamically perfused by nutrients and dissolved gas molecules; and (b) human myeloma cells seeded from a biospecimen composition comprising mononuclear cells and the multiple myeloma cells. The human myeloma cells are in contact with osteoblasts of the BM niche, and the viability of the human myeloma cells is maintained by the MM cancer niche.
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公开(公告)号：WO2020163536A8
公开(公告)日：2020-08-13
申请号：PCT/US2020/016889
申请日：2020-02-05
Applicant: HACKENSACK UNIVERSITY MEDICAL CENTER , THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
Inventor： STIFELMAN, Michael , HAZELWOOD, Vikki , TUCCI, Becky , MOHAMMEDI, Saarah , NAIR, Mithin , FRAGALE, Anthony Jr. , GALER, Alicia
Abstract: The described invention provides a ureteral stent device comprising a tubular structure comprising a proximal end and a distal end. The proximal end comprises a magnet, a magnetic tip, a magnetic coating, a magnetic metal, or a magnetic alloy. The distal end comprises a tapered tip and can form any one of a J-curl, a j- shape, or a pigtail loop for securing the distal end in a kidney. The proximal end is not secured in the bladder and terminates in the ureter.
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