Abstract:
A skin external composition for moisturizing, which contains an Astragalus membranaceus Bunge. extract is provided to increase skin moisturizing and improve xeroderma, atopic dermatitis, contact dermatitis or psoriasis. A skin external composition comprises 0.0001-20% by weight of Astragalus membranaceus Bunge. extract as an effective ingredient. The Astragalus membranaceus Bunge. extract is isolated in a extractor having a pottery. The extractor comprises a main body (110), cover of main body, heating part (130), pottery (140), and gas valve (150). A method for manufacturing the Astragalus membranaceus Bunge. extract comprises: a step of putting the material to be extracted and extraction solvent in a regular ratio; a step of closing the cover to seal the main body; a step of injecting gas into the body and discharging the air from the body; a step of supplying hot water to heat the body; a step of discharging the hot water from the body to cool the body; a step of discharging the gar from the body; and a step of opening the cover of body and collect the extract.
Abstract:
본 발명은 하기 화학식 1로 표시되는 히드록시 피라논 유도체와 그 제조방법에 관한 것이다. 본 발명에 의해 제공되는 상기 히드록시 피라논 유도체는 콜라겐 생성을 증가시키는 효과와 콜라겐을 분해하는 효소인 콜라게네이즈의 활성을 억제하는 효과로 인해 주름을 개선시키는 효과를 나타내며, 이는 의약품 및 피부외용제의 유효성분으로 이용될 수 있다.
(상기 식 중, R 1 은 -CH 2 - 또는 -CH 2 CH 2 - 이고, R 2 는 -C(O)NHCH 2 - 또는 -CH=CHC(O)NHCH 2 - 이다.) 히드록시 피라논 유도체 * 콜라겐 * 주름 개선 * 피부 외용제
Abstract:
A skin external composition is provided to increase production of tropoelastin in the skin, and productions of collagen and fibrilin in the dermis layer, so that the composition is useful for skin wrinkle improvement, skin elasticity enhancement, and skin moisturizing increase. The skin external composition for improving skin wrinkle, enhancing skin elasticity and increasing skin moisturizing comprises a mixture containing palmitoylpentapeptide, soybean embryo isoflavone aglycon, extract of Medicago sativa and extract of Iris florenti, wherein the palmitoylpentapeptide is prepared by binding a palmitoyl group to 5 amino acid chain molecule(Lys-Thr-Thr-Lys-Ser) corresponding with the protein base of collagen; the soybean embryo isoflavone aglycon is selected from genistin, daidzin, glycitin, genistein, daidzein and glycitein; and the amounts of palmitoylpentapeptide, soybean embryo isoflavone aglycon, extract of Medicago sativa and extract of Iris florenti are 0.001-20 wt.%, 0.001-20 wt.%, 0.001-20 wt.% and 0.001-20 wt.%, respectively.