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公开(公告)号：KR1020140084808A
公开(公告)日：2014-07-07
申请号：KR1020120154702
申请日：2012-12-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K38/20 , A61K8/64 , A61K9/0014 , A61Q19/02
Abstract: The present invention relates to a composition for whitening the skin, wherein the composition contains interleukin 27 (IL-27). More specifically, the present invention relates to a skin external application composition containing IL-27 so as to control the chromogenesis of adult melanocytes in the skin so that the skin can be whitened and hyperchromatism including chloasma and lentigo can be treated.
Abstract translation: 本发明涉及一种用于使皮肤美白的组合物，其中该组合物含有白细胞介素27（IL-27）。 更具体地，本发明涉及含有IL-27的皮肤外用剂组合物，以控制皮肤中成人黑素细胞的发色，从而可以使皮肤发白，并可以治疗包括黄褐斑和雀斑的过度色素沉着。
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公开(公告)号：KR1020140084806A
公开(公告)日：2014-07-07
申请号：KR1020120154700
申请日：2012-12-27
Applicant: (주)아모레퍼시픽
IPC: A61K31/4152 , A61K31/41 , A61K8/49 , A61P17/00
CPC classification number: A61K31/64 , A61K8/494 , A61K9/0014 , A61Q19/02
Abstract: The present invention relates to a skin external application composition containing SM-19712. More specifically, the skin external application composition exhibits excellent skin whitening effects by containing SM-19712, which is an antagonist of a substance P, as an active ingredient.
Abstract translation: 本发明涉及含有SM-19712的皮肤外用剂组合物。 更具体地，皮肤外用组合物通过含有作为P物质的拮抗剂的SM-19712作为活性成分，显示出优异的皮肤美白效果。
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公开(公告)号：KR1020140078973A
公开(公告)日：2014-06-26
申请号：KR1020120148356
申请日：2012-12-18
Applicant: (주)아모레퍼시픽
CPC classification number: A61K38/2086 , A61K8/64 , A61K9/0014 , A61Q19/02 , C07K14/5437
Abstract: The present invention relates to a skin whitening composition including interleukin 13 (IL-13), more specifically, to a skin preparation composition for an external use, wherein the composition comprises IL-13 to suppress a generation of a pigment and differentiation of an adult melanin cell on the skin, thereby providing a skin whitening effect; and is effective in curing hyperpigmentation skin diseases such as melasma or lentigo.
Abstract translation: 本发明涉及包含白细胞介素13（IL-13）的皮肤美白组合物，更具体地，涉及外用皮肤制剂组合物，其中所述组合物包含IL-13以抑制颜料的产生和成人的分化 皮肤上的黑色素细胞，从而提供皮肤美白效果; 并且有效地治疗色素沉着过度的皮肤疾病如黑斑病或雀斑斑。
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公开(公告)号：KR1020130140318A
公开(公告)日：2013-12-24
申请号：KR1020120063582
申请日：2012-06-14
Applicant: (주)아모레퍼시픽
Abstract: The present invention provides a composition for skin whitening which contains wortmannin as an active ingredient. The composition for skin whitening which contains wortmannin as an active ingredient according to the present invention whitens skin by reducing melanin production, suppressing tyrosinase activation and reducing expression of melanogenesis-related gene and protein and can be widely applied to skin externals, cosmetic compositions, and pharmaceutical compositions by having stability not to have bad influence on cells.
Abstract translation: 本发明提供了含有渥曼青霉素作为活性成分的皮肤美白组合物。 含有渥曼青霉素作为本发明活性成分的皮肤美白组合物通过减少黑色素产生，抑制酪氨酸酶活化和减少黑素生成相关基因和蛋白质的表达来增白皮肤，并可广泛应用于皮肤外用剂，化妆品组合物和 稳定性不会对细胞产生不良影响的药物组合物。
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公开(公告)号：KR1020130140317A
公开(公告)日：2013-12-24
申请号：KR1020120063581
申请日：2012-06-14
Applicant: (주)아모레퍼시픽
IPC: A61K8/49 , A61K31/5377 , A61Q19/02 , A61P17/00
CPC classification number: A61K8/498 , A61K31/5377 , A61Q19/02
Abstract: The present invention provides a composition containing LY294002 for skin whitening. The composition containing LY294002 for skin whitening reduces the generation of melanin, suppresses the activity of tyrosinase, and reduces the expression of genes and protein related to the generation of melanin for whitening the skin. The composition containing LY294002 for skin whitening has stability which does not have bad influence to cells, and is capable of widely applied to a skin external application, a cosmetic composition, and a pharmaceutical composition.
Abstract translation: 本发明提供含有LY294002用于皮肤美白的组合物。 含有LY294002用于皮肤美白的组合物减少黑色素的产生，抑制酪氨酸酶的活性，并减少与产生黑色素相关的基因和蛋白质的表达，以使皮肤美白。 含有用于皮肤美白的LY294002的组合物具有对细胞没有不良影响的稳定性，并且能够广泛地应用于皮肤外用剂，化妆品组合物和药物组合物。
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Patent Agency Ranking
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公开(公告)号：KR1020170063263A
公开(公告)日：2017-06-08
申请号：KR1020150169426
申请日：2015-11-30
Applicant: (주)아모레퍼시픽 , 경희대학교 산학협력단
IPC: A61K48/00 , A61K31/713 , A61K9/127 , A61K9/00 , C12Q1/68
Abstract: 본명세서는서열번호 1을포함하는 8 내지 100 mer 길이의 RNA 핵산분자를유효성분으로포함하는흑색종전이억제용조성물에관한것으로, 상기 RNA 핵산분자는서열번호 2의서열을포함할수 있으며, 본발명의일 측면에따른조성물은흑색종의전이를억제하거나흑색종전이유전자의발현을억제할수 있고, 또한, 본명세서는시험물질에대한흑색종전이억제물질을스크리닝하는방법및 흑새종전이진단용키트를제공한다.
Abstract translation: 本发明涉及用于抑制黑素合成的组合物，其包含8至100聚体长度的包含SEQ ID NO：1的RNA核酸分子作为活性成分，其中所述RNA核酸分子可以包含SEQ ID NO：2的序列， 根据本发明的一个方面的组合物可以抑制黑素瘤转移或抑制黑素
化基因的表达，此外，本发明涉及用于筛选对测试物质的抑制黑素
精症的物质的方法， 等等。
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