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公开(公告)号：US09128124B2
公开(公告)日：2015-09-08
申请号：US13764612
申请日：2013-02-11
Applicant: California Institute of Technology
Inventor： Aditya Rajagopal , Chieh-Feng Chang , Akram Sarwat Sadek , Axel Scherer , Raymond Jimenez
CPC classification number: G01R19/00 , A61B5/0031 , A61B5/04001 , A61B2560/0214 , A61B2562/0209 , A61B2562/0233 , A61B2562/164 , A61B2562/166 , A61B2562/223
Abstract: A voltage sensing apparatus on a semiconductor substrate, including one or more inputs comprising metal contacts, an output comprising a laser transmitter, circuitry electrically connecting and interfacing the inputs to the output; and a power module. A method of fabricating the apparatus is also described.
Abstract translation: 一种半导体衬底上的电压感测装置，包括一个或多个包括金属触点的输入端，包括激光发射器的输出端，将输入电连接到输出端的电路; 和电源模块。 还描述了制造该装置的方法。
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72.发明授权Compact tunable photonic crystal nanobeam cavity with low power consumption 有权具有低功耗的紧凑型可调谐光子晶体nanobeam腔公开(公告)号：US09091807B2
公开(公告)日：2015-07-28
申请号：US14051409
申请日：2013-10-10
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： William Dos Santos Fegadolli , Axel Scherer
CPC classification number: G02B6/1225 , B82Y20/00 , G02B6/107 , G02B6/1228
Abstract: Methods and devices for a tunable photonic crystal nanobeam cavity are disclosed. Such nanobeam cavity has high Q-factor and can be integrated with a microheater. The resonant wavelength of the cavity can be tuned to attain a high modulation depth with low power consumption.
Abstract translation: 公开了可调谐光子晶体纳米孔腔的方法和装置。 这样的纳米孔腔具有高Q因子，并且可以与微加热器结合。 可以调谐空腔的谐振波长以获得低功耗的高调制深度。
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公开(公告)号：US09037209B2
公开(公告)日：2015-05-19
申请号：US13706668
申请日：2012-12-06
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , SANOFI
Inventor： Axel Scherer , Remi Brouard, III , Emil P. Kartalov , Jingqing Huang
IPC: A61B5/1455 , A61B5/1459 , A61B3/10 , A61B5/145 , A61B5/00 , A61B5/20 , A61B5/1491 , A61B5/01
CPC classification number: A61B5/1459 , A61B3/10 , A61B5/0002 , A61B5/01 , A61B5/14507 , A61B5/1451 , A61B5/14546 , A61B5/1491 , A61B5/20 , A61B5/418 , A61B5/42 , A61B5/4337 , A61B5/6848 , A61B5/6852 , A61B5/6866 , A61B5/7278 , A61B2560/0219 , A61B2560/0233
Abstract: An implantable diagnostic device in accordance with the present disclosure includes a probe assembly that can be implemented in a variety of ways. A few example implementations include: a needle inside which is located a bio-sensor chip (the needle being insertable into a human being); a compact package containing the bio-sensor chip (the compact package configured for placement inside a catheter); or a silicon-based bio-sensor package configured for insertion into a vein.
Abstract translation: 根据本公开的可植入诊断装置包括可以以各种方式实现的探针组件。 一些示例性实现包括：位于其内的针，其位于生物传感器芯片（针可插入人体中）; 包含生物传感器芯片的紧凑型封装（被配置用于放置在导管内的紧凑封装）; 或被配置为插入静脉中的硅基生物传感器封装。
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74.发明授权Implantable vascular system biosensor with grown capillary beds and uses thereof 有权具有生长毛细管床的植入式血管系统生物传感器及其用途公开(公告)号：US09011330B2
公开(公告)日：2015-04-21
申请号：US13938156
申请日：2013-07-09
Applicant: California Institute of Technology
Inventor： Akram Sarwat Sadek , Axel Scherer , Muhammad Mujeeb-U-Rahman
IPC: A61B5/00 , A61B5/1455 , A61B5/1486 , A61B5/145 , A61B5/1459 , A61B5/1473
CPC classification number: A61B5/6846 , A61B5/14503 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/686 , A61B5/6876 , A61B2562/028 , A61B2562/14 , A61B2562/164
Abstract: An implantable biocompatible biosensor is described herein. The biosensor includes a chip layer including a plurality of holes fabricated vertically there through, a power source, one or more sensors on the chip layer and coupled to the power source and a hydrogel matrix including one or more angiogenesis stimulating factors in contact with the chip layer. The stimulating factors stimulate growth of organic material through the plurality of holes when the biosensor is implanted in a subject.
Abstract translation: 本文描述了可植入的生物相容性生物传感器。 生物传感器包括芯片层，其包括垂直于其上形成的多个孔，电源，芯片层上的一个或多个传感器并耦合到电源，以及水凝胶基质，其包括与芯片接触的一个或多个血管生成刺激因子 层。 当将生物传感器植入受试者时，刺激因素刺激有机材料通过多个孔的生长。
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公开(公告)号：US09006014B2
公开(公告)日：2015-04-14
申请号：US14106701
申请日：2013-12-13
Applicant: California Institute of Technology
Inventor： Muhammad Mujeeb-U-Rahman , Axel Scherer
IPC: H01L21/283 , H01L21/285 , H01L29/41 , H01L33/38 , H01L31/00
CPC classification number: H01L21/285 , A61B2562/125 , B81C1/00111 , B81C1/0038 , H01L21/02425 , H01L21/28556 , H01L24/14 , H01L29/41 , H01L31/00 , H01L33/387 , H01L2224/1401 , H01L2924/11
Abstract: A method for fabricating three dimensional high surface electrodes is described. The methods including the steps: designing the pillars; selecting a material for the formation of the pillars; patterning the material; transferring the pattern to form the pillars; insulating the pillars and providing a metal layer for increased conductivity. Alternative methods for fabrication of the electrodes and fabrication of the electrodes using CMOS are also described.
Abstract translation: 描述了制造三维高表面电极的方法。 方法包括步骤：设计支柱; 选择用于形成支柱的材料; 图案化材料; 转移模式形成支柱; 绝缘柱并提供用于增加导电性的金属层。 还描述了用于制造电极和使用CMOS制造电极的替代方法。
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Patent Agency Ranking
公开(公告)号：US08929415B2
公开(公告)日：2015-01-06
申请号：US14095372
申请日：2013-12-03
Applicant: California Institute of Technology
Inventor： Seheon Kim , Axel Scherer
IPC: H01S3/14 , H01S3/093 , H01S5/00 , H01S5/183 , B82Y20/00 , H01L31/0352 , H01S5/04 , H01S5/34 , H01L33/00 , H01S5/10
CPC classification number: H01S5/183 , B82Y20/00 , H01L31/0352 , H01L31/035281 , H01L33/0045 , H01L2933/0083 , H01S5/041 , H01S5/105 , H01S5/18319 , H01S5/18327 , H01S5/18352 , H01S5/34 , H01S5/3412 , Y02E10/50
Abstract: Photonic crystal cavities and related devices and methods are described. The described cavities can be used as lasers, photovoltaic sources, and single photon sources. The cavities can be both optically and electrically pumped. A fabrication process of the cavities is also described.
Abstract translation: 描述了光子晶体腔及相关装置和方法。 所描述的空腔可以用作激光器，光电源和单个光子源。 空腔可以光学和电气泵送。 还描述了空腔的制造工艺。
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公开(公告)号：US08873055B2
公开(公告)日：2014-10-28
申请号：US13947469
申请日：2013-07-22
Applicant: California Institute of Technology
Inventor： Imran R. Malik , Xiomara L. Madero , Erika F. Garcia , Axel Scherer
CPC classification number: G01N21/64 , G01N21/0303 , G01N21/645
Abstract: Structures and methods are described for optical detection of physical, chemical and/or biological samples. An optical detection structure may include a LED source, multiple filters and single or multiple sample areas. A detector may be used to record a fluorescence signal. The sample area may allow the introduction of removable cartridges.
Abstract translation: 描述了物理，化学和/或生物样品的光学检测的结构和方法。 光学检测结构可以包括LED源，多个滤光器和单个或多个样品区域。 检测器可用于记录荧光信号。 样品区域可能允许引入可移除的墨盒。
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公开(公告)号：US08707545B2
公开(公告)日：2014-04-29
申请号：US14038702
申请日：2013-09-26
Applicant: California Institute of Technology
Inventor： Samson Chen , Aditya Rajagopal , Axel Scherer
IPC: G01N15/00
CPC classification number: H05K3/10 , B01L3/502707 , B01L3/502715 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , H01L23/473 , H01L2924/0002 , H05K1/0272 , H05K3/284 , H05K2201/10189 , H05K2203/1327 , Y10T29/49 , Y10T29/49002 , Y10T29/49155 , Y10T29/49165 , Y10T137/85938 , Y10T436/11 , Y10T436/25 , Y10T436/2575 , H01L2924/00
Abstract: A printed circuit board structure is coated with an encapsulant within which microfluidic channels have been formed. The microfluidic channels are formed by soldering fluidic connections to metal traces on a surface of the printed circuit board structure prior to encapsulation. The metal traces are removed by etching after encapsulation to form microchannels within the encapsulant.
Abstract translation: 印刷电路板结构涂覆有已经形成微流体通道的密封剂。 在封装之前，通过将流体连接焊接到印刷电路板结构的表面上的金属迹线来形成微流体通道。 在封装后通过蚀刻去除金属迹线，以在密封剂内形成微通道。
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79.发明申请IMPLANTABLE VASCULAR SYSTEM BIOSENSOR WITH GROWN CAPILLARY BEDS AND USES THEREOF 有权可植入血管系统生物传感器，具有毛细管床及其用途公开(公告)号：US20140012122A1
公开(公告)日：2014-01-09
申请号：US13938156
申请日：2013-07-09
Applicant: California Institute of Technology
Inventor： Akram Sarwat Sadek , Axel Scherer , Muhammad Mujeeb-U-Rahman
IPC: A61B5/00
CPC classification number: A61B5/6846 , A61B5/14503 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/686 , A61B5/6876 , A61B2562/028 , A61B2562/14 , A61B2562/164
Abstract: An implantable biocompatible biosensor is described herein. The biosensor includes a chip layer including a plurality of holes fabricated vertically there through, a power source, one or more sensors on the chip layer and coupled to the power source and a hydrogel matrix including one or more angiogenesis stimulating factors in contact with the chip layer. The stimulating factors stimulate growth of organic material through the plurality of holes when the biosensor is implanted in a subject.
Abstract translation: 本文描述了可植入的生物相容性生物传感器。 生物传感器包括芯片层，其包括垂直于其上形成的多个孔，电源，芯片层上的一个或多个传感器并耦合到电源，以及水凝胶基质，其包括与芯片接触的一个或多个血管生成刺激因子 层。 当将生物传感器植入受试者时，刺激因素刺激有机材料通过多个孔的生长。
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公开(公告)号：US20240192410A1
公开(公告)日：2024-06-13
申请号：US18300145
申请日：2023-04-13
Applicant: The Boeing Company , CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Leora Peltz , Axel Scherer , Taeyoon Jeon
CPC classification number: G02B5/085 , G02B5/0883 , G02B7/183 , H05K5/0209 , B64C30/00
Abstract: One disclosed example provides a vehicle, comprising an outer shell defining an interior, a component located within the interior, and a multilayer reflector located between the outer shell of the vehicle and the component. The multilayer reflector comprises a plurality of alternating layers of a first material with a first refractive index and a second material with a second refractive index, the second refractive index being higher than the first refractive index.
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