公开(公告)号：EP1019015B1

公开(公告)日：2003-02-05

申请号：EP98910060.7

申请日：1998-02-27

Applicant: Colgate-Palmolive Company

Inventor： NABI, Nuran ,  GAFFAR, Abdul

IPC: A61K7/16

CPC classification number: A61K8/55 ,  A61K8/347 ,  A61K8/463 ,  A61Q11/00

Abstract: The invention provides an antibacterial oral composition containing an antibacterial compound such as triclosan, a monoalkyl phosphate compound and an anionic surfactant; whereby, the antibacterial effect on dental tissue is substantially increased due to the combined presence of the monoalkyl phosphate compound and the anionic surfactant.

公开(公告)号：EP0914081B1

公开(公告)日：2002-08-07

申请号：EP97921186.9

申请日：1997-04-14

Applicant: Colgate-Palmolive Company

Inventor： ZHANG, Yun, Po ,  GAFFAR, Abdul

IPC: A61K7/16

CPC classification number: A61Q11/00 ,  A61K8/64

Abstract: Stable oral compositions containing an antibacterial casein glycomacropeptide, an anionic surfactant, and a hydrolyzed protein stabilizer, which stabilizes the casein glycomacropeptide in the presence of the anionic surfactant against inactivation without substantially reducing its antibacterial properties.

公开(公告)号：EP1185237A1

公开(公告)日：2002-03-13

申请号：EP00941391.5

申请日：2000-06-14

Applicant: Colgate-Palmolive Company

Inventor： TRIVEDI, Harsh, M. ,  HERLES, Susan, M. ,  SZELES, Lori, H. ,  GAFFAR, Abdul

IPC: A61K7/16

CPC classification number: A61Q11/00 ,  A61K8/347 ,  A61K8/35

Abstract: An antibacterial combination of a nonionic halogenated diphenyl ether compound such as Triclosan and hydrogenated lupulone, the combination being particularly effective in inhibiting the growth of gram-positive bacteria and in the preparation of antiplaque oral compositions.

公开(公告)号：EP1047390A2

公开(公告)日：2000-11-02

申请号：EP99901417.8

申请日：1999-01-11

Applicant: Colgate-Palmolive Company

Inventor： MORDARSKI, Theresa, D. ,  GAFFAR, Abdul

IPC: A61K7/16

CPC classification number: A61Q11/00 ,  A61K8/24 ,  A61K8/347 ,  A61K2800/88

Abstract: A dual component antiplaque dentifrice composition in which the first component is an extrudible dentifrice composition containing a nonionic antibacterial agent in which calcium salts are absent and the second component is an extrudable dentifrice composition containing a calcium salt wherein maximum antibacterial agent uptake by dental tissue is achieved when the components and are physically separated prior to use and are mixed upon application to dental tissue.

公开(公告)号：EP0973491A1

公开(公告)日：2000-01-26

申请号：EP98913415.0

申请日：1998-04-07

Applicant: Colgate-Palmolive Company

Inventor： BLAKE-HASKINS, John, C. ,  COLLIGAN, Mary, L. ,  COLLINS, Michael, A. ,  MANDANAS, Benjamin, Y. ,  GAFFAR, Abdul

IPC: A61K7/16 ,  A61K7/18

CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/25 ,  A61K2800/88

Abstract: A composition and method is disclosed for fluoridating teeth using a two component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which a carrageenan gum having major kappa and lambda forms as the primary thickening agent and the abrasive is a silica providing an acid pH when slurried with water, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and the abrasive and carrageenan gum in an aqueous vehicle. The first and second dentifrice compounds are maintained separate from the other until mixed for application to teeth.