公开(公告)号：EP3377026A1

公开(公告)日：2018-09-26

申请号：EP16823135.5

申请日：2016-12-20

Applicant: Colgate-Palmolive Company

Inventor： SZEWCZYK, Gregory ,  MANUS, Lisa ,  SCHAEFFER-KORBYLO, Lyndsay ,  POTANIN, Andrei ,  SUBRAMANYAM, Ravi

IPC: A61K8/24 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/81 ,  A61K8/27 ,  A61K8/44

CPC classification number: A61K8/27 ,  A61K8/21 ,  A61K8/24 ,  A61K8/44 ,  A61K8/8176 ,  A61K8/8182 ,  A61K2800/58 ,  A61Q11/00 ,  A61Q11/02

Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.

公开(公告)号：EP2437854B1

公开(公告)日：2018-08-08

申请号：EP10724948.4

申请日：2010-06-03

Applicant: Colgate-Palmolive Company

Inventor： PORTER, Venda ,  MORGAN, Andre ,  JARACZ, Stanislav ,  GRONLUND, Jennifer ,  XU, Guofeng ,  WU, Donghui ,  PRENCIPE, Michael ,  SUBRAMANYAM, Ravi

IPC: A61Q11/00 ,  A61K8/58 ,  A61K31/69 ,  A61Q17/00

CPC classification number: A61Q11/00 ,  A61K8/58 ,  A61K31/69 ,  A61Q17/005 ,  Y10S514/835

Abstract: A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.

公开(公告)号：EP3233206A1

公开(公告)日：2017-10-25

申请号：EP14821478.6

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： QIAO, Baohua ,  PAN, Long ,  SZEWCZYK, Gregory ,  SUBRAMANYAM, Ravi

IPC: A61Q11/00 ,  A61K8/27 ,  A61K8/24 ,  A61K6/00 ,  A61K33/42

CPC classification number: A61K8/27 ,  A61K6/0017 ,  A61K6/0082 ,  A61K8/24 ,  A61K33/42 ,  A61K2800/58 ,  A61Q11/00

Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including an inorganic zinc salt, and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

Abstract translation: 1。一种口腔护理组合物，其具有通过组合包含无机锌盐和多个具有6个或更多个磷酸酯聚合物单元的长链多磷酸盐的成分而制成的可溶性聚磷酸锌复合物，提供磷的无机锌盐和长链多磷酸盐的相对量 锌的摩尔比至少为6：1。 还提供了一种治疗患有牙质敏感性的受试者的方法，将该口腔护理组合物施用于受试者的牙齿和牙龈。

公开(公告)号：EP3233205A1

公开(公告)日：2017-10-25

申请号：EP14821477.8

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： NAWROCKI, Shiri ,  DUBOVOY, Viktor ,  PAN, Long ,  QIAO, Baohua ,  SZEWCZYK, Gregory ,  SUBRAMANYAM, Ravi

IPC: A61Q11/00 ,  A61K8/27 ,  A61K8/24 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/24 ,  A61K8/365 ,  A61K2800/92 ,  A61Q11/00 ,  A61Q15/00

Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including a zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and a solvent, the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

Abstract translation: 一种口腔护理组合物，其具有通过将包含锌盐，具有6个或更多个磷酸酯聚合物单元的多个长链多磷酸盐和溶剂的成分组合而成的可溶性多磷酸锌络合物，有机锌盐和长链多磷酸盐的相对量提供 磷与锌的摩尔比至少为6：1。 还提供了一种治疗患有牙质敏感性的受试者的方法，将该口腔护理组合物施用于受试者的牙齿和牙龈。

公开(公告)号：EP2516608B1

公开(公告)日：2017-04-05

申请号：EP10808957.4

申请日：2010-12-22

Applicant: Colgate-Palmolive Company

Inventor： MISNER, Steve ,  PAN, Long ,  SCALA, Diana ,  HOURIGAN, Regina ,  SUBRAMANYAM, Ravi ,  FLETCHER, Dennis ,  HALL-PUZIO, Patricia ,  ANSARI, Shamim ,  LE, Derek

IPC: C11D3/12 ,  C11D3/48 ,  C11D17/00 ,  C11D3/18 ,  C11D3/382

CPC classification number: A61K8/0216 ,  A61K8/24 ,  A61K8/25 ,  A61Q19/10 ,  C11D3/126 ,  C11D3/18 ,  C11D3/382 ,  C11D3/48 ,  C11D17/006

公开(公告)号：EP2249784B1

公开(公告)日：2016-06-29

申请号：EP08732990.0

申请日：2008-03-28

Applicant: Colgate-Palmolive Company

Inventor： PRENCIPE, Michael ,  CUMMINS, Diane ,  ROBINSON, Richard, Scott ,  MELLO, Sarita, V. ,  SULLIVAN, Richard, J. ,  CHOPRA, Suman, K. ,  DEPIERRO, Karen ,  ZAIDEL, Lynette ,  CHRISTOPOULOU, Constantina ,  SUBRAMANYAM, Ravi ,  WU, Donghui ,  MORGAN, Andre, M. ,  SANTARPIA III, Ralph, Peter ,  WANG, Qin ,  TAMBS, Gary, Edward ,  KOHLI, Rajnish ,  BARNES, Virginia, Monsul ,  LEITE, Sergio ,  SIMON, Eric, A.

IPC: A61K8/44 ,  A61K8/25 ,  A61Q11/00 ,  A61K31/198 ,  A61P1/02

CPC classification number: A61K8/44 ,  A61K8/25 ,  A61K31/198 ,  A61Q11/00

Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.

Abstract translation: 本发明涉及包含碱性氨基酸或其盐和小颗粒级分的口腔护理组合物以及使用和制备这些组合物的方法。

公开(公告)号：EP2512461B1

公开(公告)日：2013-10-23

申请号：EP09775509.4

申请日：2009-12-18

Applicant: Colgate-Palmolive Company ,  Indian Institute Of Integrative Medicine

Inventor： SUBRAMANYAM, Ravi ,  DU-THUMM, Laurence ,  QAZI, Ghulam, Nabi ,  KHAN, Inshad, Ali ,  SURI, Krishan, Avtar ,  SATTI, Naresh, Kumar ,  ALI, Furqan ,  KALIA, Nitin, Pal

IPC: A61K31/00 ,  A61K31/122 ,  A61K31/341 ,  A61K31/40 ,  C07D207/00 ,  A61K45/06

CPC classification number: A61K31/122 ,  A61K31/00 ,  A61K31/341 ,  A61K31/40 ,  A61K45/06 ,  C07D207/00 ,  Y02A50/473 ,  A61K2300/00

Abstract: Compounds are described that are effective in enhancing the efficacy of antimicrobial agents. Also described are methods of using such compounds and compositions that include such compounds. The composition includes a chalcone compound and, optionally, an antimicrobial agent.

公开(公告)号：EP2539310A1

公开(公告)日：2013-01-02

申请号：EP10705965.1

申请日：2010-02-25

Applicant: Colgate-Palmolive Company ,  Indian Institute Of Chemical Technology

Inventor： REDDY, Basi, V., Subba ,  YADAV, Jhillu, S. ,  SUBRAMANYAM, Ravi

IPC: C07C37/055 ,  C07C37/62 ,  C07C39/21 ,  C07C41/48 ,  C07C41/52 ,  C07C43/313 ,  C07C43/30 ,  A61K31/05 ,  A61P31/04

CPC classification number: C07C41/48 ,  C07C37/055 ,  C07C37/62 ,  C07C41/52 ,  Y02P20/55 ,  C07C39/21 ,  C07C39/367 ,  C07C43/30 ,  C07C43/313

Abstract: A method is described for producing magnolol, or a derivative or analogue thereof. The method includes obtaining MOM ether of 5,5'-diallylbiphenyl-2,2'-diol or a derivative or analogue thereof and subsequently converting the MOM ether of 5,5'-diallylbiphenyl-2,2'-diol into magnolol or a derivative or analogue thereof.

公开(公告)号：EP2523676A1

公开(公告)日：2012-11-21

申请号：EP11706721.5

申请日：2011-02-24

Applicant: Colgate-Palmolive Company

Inventor： FEI, Lin ,  SUBRAMANYAM, Ravi ,  XU, Guofeng

IPC: A61K36/575 ,  A61K47/10

CPC classification number: A61K47/10 ,  A61K8/347 ,  A61K8/97 ,  A61K9/006 ,  A61K36/575 ,  A61K2300/00 ,  A61Q11/00

Abstract: Disclosed herein are methods of enhancing the solubility and delivery of one or more active ingredients found in magnolia extract, or a synthetic analog thereof, in an oral composition.

Abstract translation: 本文公开了在口腔组合物中增强在木兰提取物或其合成类似物中发现的一种或多种活性成分的溶解度和递送的方法。

公开(公告)号：EP1830925B1

公开(公告)日：2012-11-21

申请号：EP05854885.0

申请日：2005-12-21

Applicant: Colgate-Palmolive Company

Inventor： SUBRAMANYAM, Ravi ,  SREENIVASAN, Prem

IPC: A61Q11/00 ,  A61K8/34

CPC classification number: A61K8/347 ,  A61Q11/00