公开(公告)号：JPS60225606A

公开(公告)日：1985-11-09

申请号：JP8201884

申请日：1984-04-25

Applicant: TOYO SODA MFG CO LTD ,  SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  MATSUI KIYOHIDE ,  ONOZUKA JIYUNKO ,  UCHIKURA MASAKI ,  KIYOTA TOORU ,  AKIMOTO AKIRA

IPC: C08F251/00 ,  B01D53/22 ,  B01D71/02 ,  B01D71/70 ,  B01D71/78 ,  C08F251/02

Abstract: PURPOSE:To obtain gas permselective membrane having increased coefficient of gas transmission and high mechanical strength, by using a graft copolymer obtained from a cellulose derivative and single terminal reactive polyorganosiloxane. CONSTITUTION:A cellulose derivative represented by formula is used wherein X1-X6 are selected from a group consisting of a hydrogen atom, a lower alkyl group, an acetyl group, a benzyl group, a vinylbenzyl group, a vinyl group, a hydroxyethyl group, a nitro group and an alkoxycarbonyl group, provided that at least one of X1-X6 is a hydrogen atom, a hydroxyethyl group, a vinyl group or a vinylbenzyl group. This compound must have a functional group such as a hydroxyl group or a vinyl group capable of reacting with the reactive terminal of single terminal reactive polyorganosiloxane. As the reactive terminal of single terminal reactive polyorganosiloxane, a hydrosilyl group, a halosilyl group or an epoxy group are designated. The graft copolymer of both compounds is formed into a membrane by a known method. A membrane having a thickness of about 0.05-100mum is pref. from the aspect of gas permeability and mechanical strength.

公开(公告)号：JP2001302681A

公开(公告)日：2001-10-31

申请号：JP2000129945

申请日：2000-04-28

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA

IPC: C07F7/21 ,  C08G63/695 ,  C08G69/42

Abstract: PROBLEM TO BE SOLVED: To obtain a raw material compound when a star type aromatic polymer comprising an aromatic polyamide, an aromatic polyester, etc., as a skeleton and soluble in solvents is synthesized. SOLUTION: This cyclosiloxane compound is represented by the following general formula (I) [wherein, R1 is a 1-6C alkyl group or phenyl group; R2 is amino group or a group represented by COOR3 (wherein R3 is hydrogen atom or a protecting group of carboxyl group); X is a single bond, oxygen atom or a group represented by OOC, NHCO or OCH2; m is an integer of 3-8; p is an integer of 2-10; and q is an integer of 1 or 2].

公开(公告)号：JPH11279060A

公开(公告)日：1999-10-12

申请号：JP7918598

申请日：1998-03-26

Applicant: Sagami Chem Res Center ,  Sankyo Co Ltd ,  三共株式会社 ,  財団法人相模中央化学研究所

Inventor： OKADA JUNICHI ,  INOUE KAZUHIRO ,  NAGASE YUTAKA ,  AKIMOTO TOMOKO ,  AOYANAGI TAKAO

IPC: A61K47/24 ,  A61K31/42 ,  A61K31/425 ,  A61K31/44 ,  A61P9/00

Abstract: PROBLEM TO BE SOLVED: To obtain a percutaneous absorption composition which is remarkably improved in percutaneous absorbability by adding a specific polyorganosiloxane- based percutaneous absorption promoting compound to a specific thia or oxazolidinone-based antistenocardia compound. SOLUTION: This composition contains a polyorganosiloxane-based percutaneous absorption promoting compound of formula I (R -R are each a 1-6C alkyl or phenyl; R -R are each a 1-6C alkyl, phenyl or the like; Z is a pair anion on quaternary salts, (p) is an integer of 2-6; (q) is an integer of 1-6; (m) and (n) are each a real number of 1-20; y is a 1-6C alkyl or the like) and a thia or oxazolidinone-based antistenocardia compound of formula II [W is S or O; X is a group of the formula: -N(R a )- (R a is H, a 1-6C alkyl or the like) or the like; R a and R a are each H, a 1-6C alkyl or the like; R a is H, a 1-6C alkyl or the like; A is a 2-6C alkylene or the like], as active ingredients and it is the composition for prevention or treatment for stenocardia with a real number of 2 or more in ER(enhancement radio).

Abstract translation: 要解决的问题：为了获得通过将特定的基于聚有机硅氧烷的经皮吸收促进化合物添加到特定的硫唑酮或恶唑烷酮基抗心肌酸酯化合物中而获得经皮吸收性显着提高的经皮吸收组合物。 解决方案：该组合物含有式I的聚有机硅氧烷基经皮吸收促进化合物（R 1 -R 6各自为1-6C烷基或苯基; R 7 -R 9各自为1- 6C烷基，苯基等; Z是季盐上的对阴离子，（p）是2-6的整数;（q）是1-6的整数;（m）和（n） 1-20; y是1-6C烷基等）和式II的噻唑或恶唑烷酮基抗心动酸抗体化合物[W是S或O; X是下式的基团：-N（R a a） - （R a a是H，1-6 C烷基等）等; R 2a和R 3a各自为H，1-6C烷基等; R 4是H，1-6C烷基等; A是2-6C亚烷基等]作为活性成分，并且其是ER（增强型无线电）中实际数量为2以上的心内膜的预防或治疗的组合物。

公开(公告)号：JPH1180114A

公开(公告)日：1999-03-26

申请号：JP24369597

申请日：1997-09-09

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  AKIYAMA EIICHI ,  KOIDE NAOYUKI ,  ARAKI KAZUO

IPC: C07C255/54 ,  C08F20/36 ,  C08F299/00 ,  C09K19/38

Abstract: PROBLEM TO BE SOLVED: To obtain the subject new compound which is a precursor compound of a side-chain type polymer liquid crystal, having stable liquid crystallinity at a relatively low temperature and useful as a display element and a recording material in the electronics field and a functional material used for nonlinear optical materials, a dimming glass and the like. SOLUTION: This compound is represented by formula I [A is a single bond, O, S or COO; Q is a liquid crystal group; (x) is 1-6; (y) is 4-12]. The compound represented by formula I is obtained by reacting ethylene glycol or an oligoethylene oxide represented by formula II with a compound represented by formula III (Y is a halogen except F) in the presence of preferably one equivalent base (e.g. an inorganic base such as lithium hydroxide or potassium hydroxide and an alkali metal hydride such as sodium hydride or potassium hydride), at 0-100 deg.C reactional temperature in an organic solvent (e.g. tetrahydrofuran or dimethoxyethane) in an inert gas atmosphere such as argon or nitrogen.

公开(公告)号：JPH1160414A

公开(公告)日：1999-03-02

申请号：JP22646797

申请日：1997-08-22

Applicant: SAGAMI CHEM RES ,  K I KASEI KK

Inventor： NAGASE YUTAKA ,  AKIMOTO TOMOKO ,  AOYANAGI TAKAO ,  TANAKA KAZUNORI ,  SANO YOSHINORI ,  MOCHIZUKI KENJI ,  ISOGAI KATSUHISA

IPC: A01N43/40 ,  A01N59/16 ,  A01N59/20 ,  C08L79/00

Abstract: PROBLEM TO BE SOLVED: To obtain a thermally stable, safe composition having high bactericidal and fungicidal activity and free from foaming by compounding a specific polycation having a pyridinium group on the main chain structure and a copper ion and/or a silver ion. SOLUTION: This composition is composed of at least one kind of a polymer comprising (A) a recurrent unit expressed by the formula [X1 and X2 are each a pairing anion in a quaternary salt, i.e., a halide ion, a conjugate base of a mineral acid, an aliphatic carboxylic acid ion, an aromatic carboxylic acid ion, an alkylphosphoric acid ester ion, etc.; (m)=O-6] and having a number average molecular weight of >=1,000, preferably >=3,000, and (B) a copper ion and/or a silver ion preferably at a ratio of the component A: the component B (weight ratio) = (99:1)-(10:90). It is preferable that the microbicidal composition is added to the objective aqueous system in such an amount that the polymer from the component A becomes 0.1-20 ppm, and further the copper ion and the silver ion become 0.1-5 ppm and 0.001-3 ppm, respectively.

公开(公告)号：JPH1112355A

公开(公告)日：1999-01-19

申请号：JP16393697

申请日：1997-06-20

Applicant: SAGAMI CHEM RES ,  NISSAN CHEMICAL IND LTD

Inventor： NAGASE YUTAKA ,  AKIYAMA EIICHI ,  MIYAMA YUKIHIRO ,  ENDO HIDEYUKI ,  NIHEI TAKAYASU ,  NAWATA HIDEYUKI ,  TAI HIROYOSHI

IPC: G02F1/1337 ,  C08G69/08 ,  C08G69/12

Abstract: PROBLEM TO BE SOLVED: To obtain a polyamide useful as a treating agent for orientation, capable of being baked at a lower temperature and uniformly orientating a ferroelectric liquid crystal and an antiferroelectric liquid crystal without causing defects, by making the molar ratio of specific plural repeating units in a specific range. SOLUTION: This polyamide comprises a repeating unit of formula I (A is a single bond, a 2-12C alkylene, a group of formula II, etc.; A is a single bond, a 2-12C alkylene, a group of formula III, etc.; R , R and R are each a halogen, a 1-6C alkyl or alkoxy; X and X are each a single bond, 0 or S; n , n and n are each 0-2) and a repeating unit of formula IV (R is a halogen, a 1-6C alkyl or alkoxy; n is 0-2) in the molar ratio of the repeating units of formula I to formula V in the range of 90/10 to 10/90 and has >=1,000 weight- average molecular weight.

公开(公告)号：JPH10101669A

公开(公告)日：1998-04-21

申请号：JP25408796

申请日：1996-09-26

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  NEMOTO NAGAKATSU ,  MIYATA FUSAE ,  ABE JIRO ,  SHIRAI YASUO

IPC: G02F1/35 ,  C07D401/04 ,  C07D401/06 ,  C08F220/34 ,  G02F1/355 ,  G02F1/361

Abstract: PROBLEM TO BE SOLVED: To obtain a new compound useful as a material for optical control devices, nonlinear optical devices, electro-optical devices or the like such as wavelength transform elements, waveguides, light shutters, optical switches, optical polarized light elements and phase modulation elements, each making use of nonlinear optical effect. SOLUTION: This new compound is shown by formula I [R is H, a lower alkyl, halogen, etc.; R and R are each H, a lower alkyl, etc.; A is a single bond or 0; Y is N or a substituent R-bearing C (R is H, a lower alkyl or phenyl); Z is a single bond, methylene or vinylene; (m) is 0-6; when (m) is 0, A is a single bond], e.g. 2-(4- 2-[4-(2-methacryloyloxyethoxy) phenyl]ethenyl}-1- pyridinio)-benzimidazolate. The compound of formula I is obtained by the following process: a compound of formula II (X is a halogen except F) is reacted with a stilbazole compound of formula III to synthesize a quaternary salt compound, on which a base is then made to act to form a betaine compound, which, in turn, is condensed with an acrylic acid derivative of formula IV.

公开(公告)号：JPH107670A

公开(公告)日：1998-01-13

申请号：JP24993596

申请日：1996-09-20

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  NEMOTO NAGAKATSU ,  MIYATA FUSAE ,  ABE JIRO ,  SHIRAI YASUO

IPC: G02F1/35 ,  C07D401/04 ,  C07D401/06 ,  G02F1/355 ,  G02F1/361

Abstract: PROBLEM TO BE SOLVED: To obtain a new betaine compound having excellent secondary molecular polarizability and suitable for the photoelectronic field as an organic non- linear optical material, etc., generating high secondary harmonics, having a pyridinium structure and another nitrogen-containing heterocyclic structure. SOLUTION: This new betaine compound is expressed by the formula I [Y is a nitrogen atom or a carbon atom having a substituting group R (R is H, a lower alkyl or phenyl); Z is a single bond, methylene or vinylene; R and R are each H, a lower alkyl or form an aromatic ring in one body with a carbon atom on which the respective of the R and R are bonded; R to R are each H, a halogen, a phenyl, a 1-20C alkoxy, cyano or nitro; (m) is 0 or 1], having excellent secondary molecular polarizability (β-value), capable of dispersing into a polymer matrix, and useful as an organic non-linear optical material, etc., generating high secondary harmonics. The compound is obtained by reacting a nitrogen-containing heterocyclic compound of the formula II (X is a halogen) with a pyridine derivative of the formula III and acting with a base.

公开(公告)号：JPH09221671A

公开(公告)日：1997-08-26

申请号：JP3038296

申请日：1996-02-19

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  AKIYAMA EIICHI ,  TAKAMURA YURIKO ,  IKEDA TOMIKI ,  KANAZAWA AKIHIKO

IPC: G02F1/13 ,  C08F20/26 ,  C08F20/34 ,  C08F30/08 ,  C08F220/26 ,  C08F220/34 ,  C08F230/08 ,  C09K19/40

Abstract: PROBLEM TO BE SOLVED: To obtain the subject material having a specific number averaged molecular weight, consisting of a specific repeating unit, capable of exciting a reversible optical phase transition at a high are in a low temperature region and useful as a rewriting-type optical recording material, etc. SOLUTION: This polymer liquid crystal photonics material consists of a repeating unit having >=1000 number average molecular weight and expressed by formula I [R is H, a halogen, a 1-6C alkyl or phenyl; X is a single bond, O, COO or OCO; Q is a liquid crystal group; (k) is 2-20] and a repeating unit of formula II [R' is R; R to R are each a 1-6C alkyl or phenyl; Q is Q ; (m), (p) are each 2-10; (n) is 0-10], in which at least one of Q and Q is the liquid crystal group containing an azobenzene residue, and also contains the repeating units of the formula I and II in (95/5)-(5/95) molar ratio.

公开(公告)号：JPH08295707A

公开(公告)日：1996-11-12

申请号：JP10286695

申请日：1995-04-27

Applicant: SAGAMI CHEM RES

Inventor： NAGASE YUTAKA ,  AOYANAGI TAKAO

IPC: A61L27/00 ,  C07C219/06 ,  C08F12/00 ,  C08F212/14 ,  C08F220/10 ,  C08F290/06

Abstract: PURPOSE: To obtain a skin model membrane showing improved functions as a skin-like membrane when subjected to an in vitro examination of the permea tion of a drug through the skin by using a polymer of a specified styrene deriva tive having a long-chain alkyl group. CONSTITUTION: A reaction product of (chloromethyl)styrene with a dialcoholamine compound is reacted with an aliphatic carboxylic acid chloride at room temperature to 100 deg.C in an organic solvent to obtain a styrene derivative having a long-chain alkyl group and represented by the formula (wherein A is a 2-6C polymethylene chain which may be substituted with a methyl or ethyl group; and m is an integer of 10-30). This derivative is polymerized at 40-100 deg.C in the presence of a radical polymerization initiator in an organic solvent to obtain a polymer having long-chain alkyl groups at the side chain positions. A skin-like model membrane is obtained by forming this polymer into a membrane by e.g. a solvent cast process, a melt molding process or by impregnating or coating a porous membrane with a solution formed by dissolving the polymer in a suitable solvent.