Method for anion-exchange adsorption and anion-exchangers
    72.
    发明授权
    Method for anion-exchange adsorption and anion-exchangers 有权
    阴离子交换吸附和阴离子交换剂的方法

    公开(公告)号:US06702943B1

    公开(公告)日:2004-03-09

    申请号:US10130958

    申请日:2002-09-16

    CPC classification number: B01J41/20 B01D15/327 B01J41/09 C02F1/42

    Abstract: A method for the removal of a substance carrying a negative charge and being present in an aqueous liquid (I). The method comprises the steps of: (i) contacting the liquid with a matrix carrying a plurality of ligands comprising a positively charged structure and a hydrophobic structure, and (ii) desorbing the substance. The characterizing feature is that (I) each of said ligands together with a spacer has the formula: —SP—[Ar—R1—N+(R2R3R4)] where (A) [Ar—R1—N+(R2R3R4)] represents a ligand a) Ar is an aromatic ring, b) R1 is [(L)nR′1]m where n and m are integers selected amongst zero or 1; L is amino nitrogen, ether oxygen or thioether sulphur; R′1 is a linker selected among 1) hydrocarbon groups; 2) —C(═NH)—; c) R2-4 are selected among hydrogen and alkyls; (B) SP is a spacer providing a carbon or a heteroatom directly attached to Ar—R1—N+(R2R3R4); (C)—represents that SP replaces a hydrogen in (Ar—R1—N+(R2R3R4); (D)—represents binding to the matrix; and (II) desorption. There is also described (a) anion-exchangers having high breakthrough capacities, (b) a screening method and (c) a desalting protocol.

    Abstract translation: 一种用于去除携带负电荷并存在于水性液体(I)中的物质的方法。 该方法包括以下步骤:(i)使液体与承载包含带正电结构和疏水结构的多个配体的基质接触,和(ii)解吸该物质。 其特征在于:(I)每个所述配体与间隔基一起具有下式:-SP- [Ar-R1-N +(R2R3R4)]其中(A)[Ar-R1-N +( R2R3R4)]表示配体a)Ar是芳环,b)R1是[(L)nR'1] m,其中n和m是选自零或1的整数; L为氨基氮,醚氧或硫醚硫; R'1是选自1)烃基的连接体; 2)-C(= NH) - ; c)R2-4选自氢和烷基; (B)SP是提供直接与Ar-R 1 -N +(R 2 R 3 R 4)连接的碳或杂原子的间隔基; (C) - 表示SP替代(Ar-R1-N +(R2R3R4)中的氢;(D) - 表示与基质的结合;和(II)解吸,还描述了(a)阴离子交换 具有较高的突破能力,(b)筛选方法和(c)脱盐方案。

    FLUORIDE TRAPPING ARRANGEMENT
    77.
    发明申请
    FLUORIDE TRAPPING ARRANGEMENT 审中-公开
    氟化物捕捉装置

    公开(公告)号:WO2016075259A1

    公开(公告)日:2016-05-19

    申请号:PCT/EP2015/076475

    申请日:2015-11-12

    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [ 18 F] labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [ 18 F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [ 18 F]fluoride and recovery of [ 18 0]water.

    Abstract translation: 本发明提供了一种新的化学方法,新的盒式结构和用于在单个盒上自动生产多批[18F]标记化合物的新软件。 本发明允许在一个热电池中的一个合成器在同一天顺序地产生多批[18F]标记的PET示踪剂。 特别地,本发明提供了一种用于捕获[18 F]氟化物和回收[180]水的新颖布置。

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