公开(公告)号：US3560577A

公开(公告)日：1971-02-02

申请号：US3560577D

申请日：1968-09-18

Applicant: DU PONT

Inventor： BENJAMINS EDWIN

IPC: C07C17/42 ,  C07C201/04 ,  C07C203/00 ,  C08F36/16 ,  C07C81/00 ,  C07C81/02

CPC classification number: C07C17/42 ,  C07C201/04 ,  C08F36/16 ,  C07C21/21 ,  C07C203/00

Abstract: REACTION PRODUCTS OF NITROUS ACID AND 1.3-DICHLOROBUTENE-2 OR DISOBUTYLENE, USEFUL AS INHIBITORS OF "POPCORN" POLYMER FORMATION IN CHLOROPRENE POLYMERIZATION REACTIONS, ARE MADE BY A CONTROLLABLE PROCESS COMPRISING (1) ADDING AN ALKALI OR ALKALINE EARTH METAL NITRITE TO LIQUID 1,3-DICHLOROBUTENE-2 OR DIISOBUTYLENE WITH AGITATION, (2) SLOWLY ADDING CONCENTRATED HYDROCHLORIC OR SULFURIC ACID TO THE MIXTURE SO OBTAINED, AND (3) RECOVERING A REACTION PRODUCT OF NITROUS ACID AND 1,3-DICHLOROBUTENE2 OR DIISOBUTYLENE FROM THE BY-PRODUCT ALKALI OR ALKALINE EARTH METAL SALT FORMED.

公开(公告)号：US2739166A

公开(公告)日：1956-03-20

申请号：US20167650

申请日：1950-12-19

Applicant: TREACY JOHN C

Inventor： TREACY JOHN C

IPC: C07C201/04 ,  C07C203/00

CPC classification number: C07C201/04 ,  C07C203/00

公开(公告)号：US2474901A

公开(公告)日：1949-07-05

申请号：US2474901D

CPC classification number: C07C201/00 ,  C07C201/04 ,  C07C207/00

公开(公告)号：US2435570A

公开(公告)日：1948-02-10

申请号：US2435570D

CPC classification number: C07C201/04 ,  C07C201/00 ,  C07C207/00

公开(公告)号：JP6070695B2

公开(公告)日：2017-02-01

申请号：JP2014509081

申请日：2013-02-27

Applicant: 宇部興産株式会社

Inventor： 田中 秀二 ,  井伊 宏文 ,  日野 彰 ,  福井 裕也 ,  上田 理

IPC: C07C203/00 ,  C07C69/36 ,  C07C69/96 ,  C07C68/00 ,  C07C201/04

CPC classification number: C07C201/04 ,  C07C67/36 ,  C07C68/00

公开(公告)号：JP5191477B2

公开(公告)日：2013-05-08

申请号：JP2009500332

申请日：2007-03-14

Applicant: ラーシュ・エー・グスタフソンLars E. GUSTAFSSON ,  ダグ・リンナショーンDag LINNARSSON ,  クリストファー・ニルソンKristofer NILSSON

Inventor： ラーシュ・エー・グスタフソン ,  ダグ・リンナショーン ,  クリストファー・ニルソン

IPC: C07C201/04 ,  A61J1/00 ,  A61K31/21 ,  A61K47/10 ,  A61K47/26 ,  A61K47/34 ,  A61K47/36 ,  A61P1/04 ,  A61P3/12 ,  A61P9/00 ,  A61P9/04 ,  A61P9/06 ,  A61P9/10 ,  A61P9/12 ,  A61P11/00 ,  A61P11/06 ,  A61P13/02 ,  A61P13/10 ,  A61P17/00 ,  A61P17/02 ,  A61P17/06 ,  A61P21/00 ,  A61P25/00 ,  A61P29/00 ,  A61P35/00 ,  C07C203/00

CPC classification number: C07C201/04 ,  C07B43/02 ,  C07C203/00

Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.

公开(公告)号：JP2011236209A

公开(公告)日：2011-11-24

申请号：JP2011090875

申请日：2011-04-15

Applicant: China Petroleum & Chemical Corp ,  Shanghai Research Inst Of Petrochemical Technology Sinopec ,  中国石油化工股▲ふん▼有限公司 ,  中國石油化工股▲フン▼有限公司上海石油化工研究院

Inventor： LIU JUNTAO ,  LI SIQIN ,  LI LEI ,  ZHANG LINNA

IPC: C07C201/04 ,  C07B61/00 ,  C07C203/04

CPC classification number: C07C201/04 ,  C07C203/00

Abstract: PROBLEM TO BE SOLVED: To provide a new method for producing C-Calkyl nitrite having advantage of high selectivity of C-Calkyl nitrite.SOLUTION: This method for producing C-Calkyl nitrite includes processes for: loading a resin catalyst layer and/or a porous filler layer into a reactor; passing nitrogen oxide, oxygen and C-Calcohol as raw materials through the resin catalyst layer and/or porous filler layer in a counter current, parallel current or cross current manner; and reacting under the reaction conditions including a reaction temperature of 0-150°C, a reaction pressure of -0.09 to 1.5 MPa, a molar ratio of C-Calkanol/nitrogen oxide of 1-100:1, a molar ratio of nitrogen oxide/oxygen of 4-50:1, to obtain waste liquid containing C-Calkyl nitrite; wherein the nitrogen oxide is NO, or a mixed gas containing NO and one or more selected from NOand NO.

Abstract translation: 要解决的问题：提供一种新方法，用于生产具有优势的C 1 选择性C 1 -C 4 亚硝酸烷基酯。

解决方案：用于生产C 1 -C 4 亚硝酸烷基酯的方法包括以下步骤：将树脂催化剂层和 /或多孔填料层进入反应器; 通过树脂催化剂层和/或多孔填料层作为原料通过氮氧化物，氧气和C 1 -C 4 以逆流，并联电流或交叉电流方式; 在反应温度0〜150℃，反应压力-0.09〜1.5MPa，摩尔比C 1 -C 4 链烷醇/氮氧化物为1-100:1，氮氧化物/氧气的摩尔比为4-50:1，得到含有C 1 -C 4 亚硝酸烷基酯; 其中氮氧化物为NO，或含有NO的混合气体和选自N 3 和NO < SB POS =“POST”> 2 。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：US09499473B2

公开(公告)日：2016-11-22

申请号：US14389583

申请日：2013-02-27

Applicant: UBE INDUSTRIES, LTD.

Inventor： Syuji Tanaka ,  Hirofumi Il ,  Akira Hino ,  Yuya Fukui ,  Satoshi Ueda

IPC: C07C201/04 ,  C07C68/00 ,  C07C67/36

CPC classification number: C07C201/04 ,  C07C67/36 ,  C07C68/00 ,  C07C69/96 ,  C07C69/36 ,  C07C203/00

Abstract: A method for producing nitrous acid ester in which nitric oxide, oxygen, and an alcohol are reacted, thereby generating nitrous acid ester includes a step of generating nitrous acid ester by supplying a bottom liquid from a bottom part of the reaction column, and nitric oxide and/or carbon monoxide, a step of supplying nitrous acid ester to the reaction column; a step of supplying a reaction liquid containing water, nitric acid, and the alcohol to a nitric acid condensing column from the reactor; and a step of separating a low-boiling point component by distillation from the reaction liquid under control of a concentration of the alcohol in a condensed liquid being generated at a bottom part of the nitric acid condensing column to be less than 4.0% by weight so as to introduce the condensed liquid into the reactor from the nitric acid condensing column.

Abstract translation: 一氧化氮，氧和醇反应生成亚硝酸酯的方法，从而产生亚硝酸酯包括通过从反应塔的底部供应底部液体和一氧化氮产生亚硝酸酯的步骤 和/或一氧化碳，向反应塔供应亚硝酸酯的步骤; 将含有水，硝酸和醇的反应液体从反应器供给到硝酸冷凝塔的步骤; 在硝酸浓缩塔的底部产生的冷凝液中，醇的浓度控制下，通过蒸馏将反应液中的低沸点成分分离成低于4.0重量％的步骤，从而 将浓缩的液体从硝酸冷凝塔引入反应器。

公开(公告)号：US20150105475A1

公开(公告)日：2015-04-16

申请号：US14054194

申请日：2013-10-15

Applicant: Southwest Research Institute

Inventor： Joseph A. McDONOUGH ,  Darrel W. JOHNSTON ,  Paul M. THOMPSON

IPC: C07C201/04 ,  A61M5/19

CPC classification number: C07C201/04 ,  C07C203/00

Abstract: The present disclosure relates to devices and methods for the preparation of amyl nitrite formulations at a point of use location from relatively shelf-stable reagents employing acidic cationic exchange resins.

Abstract translation: 本公开涉及在使用酸性阳离子交换树脂的相对稳定的试剂的使用位置制备亚硝酸戊酯制剂的装置和方法。

公开(公告)号：US08722918B2

公开(公告)日：2014-05-13

申请号：US13088253

申请日：2011-04-15

Applicant: Juntao Liu ,  Siqin Li ,  Lei Li ,  Linna Zhang

Inventor： Juntao Liu ,  Siqin Li ,  Lei Li ,  Linna Zhang

IPC: C07C201/04

CPC classification number: C07C201/04 ,  C07C203/00

Abstract: The present invention relates to a process for producing C1-C4 alkyl nitrite, comprising loading a resin catalyst layer and/or a porous filler layer into a reactor, passing nitrogen oxide, oxygen and C1-C4 alkanol as raw materials through the resin catalyst layer and/or porous filler layer in a counter current, parallel current or cross current manner, reacting under the conditions including a reaction temperature of from 0 to 150° C., a reaction pressure of from −0.09 to 1.5 MPa, a molar ratio of C1-C4 alkanol/nitrogen oxide of 1-100:1, a molar ratio of nitrogen oxide/oxygen of 4-50:1, to obtain an effluent containing C1-C4 alkyl nitrite, wherein said nitrogen oxide is NO, or a mixed gas containing NO and one or more selected from N2O3 and NO2.

Abstract translation: 本发明涉及一种生产C1-C4烷基亚硝酸盐的方法，包括将树脂催化剂层和/或多孔填料层装入反应器中，使氮氧化物，氧和C1-C4链烷醇作为原料通过树脂催化剂层 和/或多孔填料层，以相对电流，并联电流或交叉电流方式，在0〜150℃的反应温度，-0.09〜1.5MPa的反应压力，-0.09〜1.5MPa的反应压力， C1-C4链烷醇/氮氧化物为1-100:1，氮氧化物/氧摩尔比为4-50:1，得到含有C 1 -C 4烷基亚硝酸盐的流出物，其中所述氮氧化物为NO，或混合 含有NO和选自N 2 O 3和NO 2中的一种或多种的气体。