公开(公告)号：US5352963A

公开(公告)日：1994-10-04

申请号：US785553

申请日：1991-10-31

Applicant: Steven A. Garand ,  Carl P. Daniel

Inventor： Steven A. Garand ,  Carl P. Daniel

IPC: H02P8/16 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  H02P8/00

CPC classification number: G01N35/1002 ,  G01N35/028 ,  G01N2021/1759 ,  G01N2035/00079 ,  G01N2035/00455 ,  G01N2035/042 ,  G01N2035/0425 ,  G01N2035/0463 ,  G01N2035/0475 ,  G01N2201/0407 ,  G01N2201/0446 ,  G01N2201/08 ,  G01N2201/1283 ,  G01N35/025

Abstract: An improved control system for a stepper motor coil includes a flyback circuit that dissipates coil energy slowly while the coil is energized and operated in the chopping mode, while dissipating coil energy rapidly when the coil is switched to its de-energized phase.

Abstract translation: 用于步进电动机线圈的改进的控制系统包括回扫电路，其在线圈被通电并且以斩波模式操作时缓慢地消散线圈能量，同时当线圈切换到其断电阶段时迅速消散线圈能量。

公开(公告)号：US5216488A

公开(公告)日：1993-06-01

申请号：US780958

申请日：1991-10-23

Applicant: Jukka Tguunanen ,  Aimo Kainiemi

Inventor： Jukka Tguunanen ,  Aimo Kainiemi

IPC: G01N21/01 ,  G01N21/25

CPC classification number: G01N21/253 ,  G01N2201/0407 ,  G01N2201/0826

Abstract: The invention relates to a method and apparatus for conducting light onto cuvettes in a photometer. Onto each cuvette in a row, there is successively conducted light through a moving light-cutting disc (8), which is provided with a slot (10) at each light path. Thus the light passing through the adjacent cuvette does not disturb the measurement.

Abstract translation: 本发明涉及一种用于在光度计中对比色皿进行光的方法和装置。 在连续的每个比色皿上，通过在每个光路处设置有狭槽（10）的移动的光盘（8）连续地引导光。 因此，穿过相邻的比色皿的光不会影响测量。

公开(公告)号：US4762420A

公开(公告)日：1988-08-09

申请号：US30176

申请日：1987-03-25

Applicant: Alan R. Bowley

Inventor： Alan R. Bowley

IPC: G01N21/13 ,  G01N21/25 ,  G01N21/59

CPC classification number: G01N21/253 ,  G01N2201/0407 ,  G01N2201/0446 ,  G01N2201/0621

Abstract: A photometric reading device comprises a plurality of reading elements (30), each comprising a light emitting diode and a corresponding photodiode on opposing sides of a sample pathway along which a sample microplate (10) can travel. The microplate (10) includes rows of sample wells arranged transverse to the line of relative motion of the microplate (10) and the reading elements (30).The reading elements (30) are arranged such that, during continuous relative motion of the reading elements (30) and the microplate (10), the reading elements (30) come into registration sequentially with the wells in the first row of wells in the microplate (10), then with the wells in the second row of wells, and so on.

Abstract translation: 光度读取装置包括多个读取元件（30），每个读取元件（30）包括发光二极管和相应的光电二极管，所述对应的光电二极管位于样品通路的相对侧，样品微孔板可以沿着样本路径行进。 微板（10）包括横列于微板（10）和读取元件（30）的相对运动线的样本阱排。 读取元件（30）被布置成使得在读取元件（30）和微板（10）的连续相对运动期间，读取元件（30）顺序地与第一排孔中的孔对准 微板（10），然后与第二排孔中的孔等等。

公开(公告)号：US4740460A

公开(公告)日：1988-04-26

申请号：US748805

申请日：1985-06-26

Applicant: Yoshitsugu Sakata ,  Haruki Oishi ,  Yasumichi Hatayama ,  Hiromi Shiraishi ,  Kazuya Yanagisawa

Inventor： Yoshitsugu Sakata ,  Haruki Oishi ,  Yasumichi Hatayama ,  Hiromi Shiraishi ,  Kazuya Yanagisawa

IPC: G01N21/83 ,  G01N33/48 ,  G01N33/50 ,  G01N33/579

CPC classification number: G01N33/579 ,  G01N21/83 ,  G01N33/50 ,  G01N2201/0407 ,  Y10S436/805

Abstract: Endotoxin contents in samples can be determined qualitatively, or quantitatively, singly or in parallel, with high precision in a short time by a process comprising applying a light to each sample solution, measuring an initial transmitted light amount I.sub.0 and a transmitted light amount at a time t, I(t), to give a ratio R(t)=I(t)/I.sub.0, and judging a gelation point by a threshold value of R(t), or further obtaining a gelation time from the gelation point. An apparatus used therefor is also disclosed.

公开(公告)号：US20180038801A1

公开(公告)日：2018-02-08

申请号：US15787747

申请日：2017-10-19

Applicant: WALLAC OY

Inventor： Ville LAITALA

IPC: G01N21/75 ,  G01D18/00 ,  G01N21/64

CPC classification number: G01N21/75 ,  G01D18/00 ,  G01N1/286 ,  G01N21/253 ,  G01N21/474 ,  G01N21/6452 ,  G01N21/6486 ,  G01N2001/2873 ,  G01N2201/0407 ,  G01N2201/101 ,  G01N2201/103

Abstract: A measurement device includes mechanical support elements (101-104) for supporting a sample well, other mechanical support elements (105-109) for supporting a measurement head (112) suitable for optical measurements, and a control system (111) configured to control the measurement head to carry out at least two optical measurements from at least two different measurement locations inside the sample well, where each measurement location is a center point of a capture range from which radiation is captured in the respective optical measurement. The final measurement result is formed from the results of the at least two optical measurements in accordance with a pre-determined rule. The use of the at least two optical measurements from different measurement locations reduces measurement variation in situations where the sample well (153) contains a piece (158) of sample carrier.

公开(公告)号：US20170191933A1

公开(公告)日：2017-07-06

申请号：US15389897

申请日：2016-12-23

Applicant: Gen-Probe Incorporated

Inventor： David OPALSKY ,  Srajan RAGHUWANSHI ,  James BUI

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N21/0332 ,  G01N21/276 ,  G01N21/75 ,  G01N35/00732 ,  G01N35/025 ,  G01N2021/6441 ,  G01N2035/00356 ,  G01N2035/0455 ,  G01N2035/0475 ,  G01N2035/0484 ,  G01N2201/0407 ,  G01N2201/0415 ,  G01N2201/12723

Abstract: A system for measuring optical signal detector performance includes an optical signal detector comprising a first detection channel having a first light source and a first sensor. The first detection channel is configured to emit and focus light generated by the first light source at a first detection zone, and to receive and focus light on the first sensor. The system also includes a controller operatively coupled to the optical signal detector and configured to determine an operational performance status of the optical signal detector based on at least one of (i) a first measured characteristic of light focused on the sensor while a first non-fluorescent surface portion is in the first detection zone and (ii) a second measured characteristic of light focused on the sensor while a void is in the first detection zone. The optical signal detector can be a fluorometer.

公开(公告)号：US20160299070A1

公开(公告)日：2016-10-13

申请号：US15070211

申请日：2016-03-15

Applicant: Bio-Rad Laboratories Inc.

Inventor： Yochanan URI ,  Boaz RAN ,  Ariel G. NOTCOVICH ,  Shay NIMRI

IPC: G01N21/552 ,  G01N33/543

CPC classification number: G01N21/553 ,  G01N21/253 ,  G01N21/658 ,  G01N33/54373 ,  G01N2021/0328 ,  G01N2201/0407 ,  G01N2201/0484 ,  G01N2201/062

Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.

公开(公告)号：US09354179B2

公开(公告)日：2016-05-31

申请号：US13911115

申请日：2013-06-06

Applicant: Bio-Rad Laboratories Inc.

Inventor： Yochanan Uri ,  Boaz Ran ,  Ariel G. Notcovich ,  Shay Nimri

IPC: G01N21/01 ,  G01N30/60 ,  G01N30/88 ,  G01N21/65 ,  G01N21/552 ,  G01N21/25 ,  G01N21/03

CPC classification number: G01N21/553 ,  G01N21/253 ,  G01N21/658 ,  G01N33/54373 ,  G01N2021/0328 ,  G01N2201/0407 ,  G01N2201/0484 ,  G01N2201/062

Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.

Abstract translation: 一种用于光学检测系统的尖端，用于使用从分析物结合到所述尖端内部的检测表面反射的光来分析吸入所述尖端的流体样品中的分析物，所述检测表面包括第一检测表面和位于 相同的流动路径，没有可分离它们的可控阀，其中第一和第二检测表面具有不同的表面化学性质。

公开(公告)号：US20150219554A1

公开(公告)日：2015-08-06

申请号：US14170558

申请日：2014-01-31

Applicant: The Boeing Company

Inventor： Daniel E. Hedges ,  Mark J. Holland ,  Scott S. Rhodes ,  Jennifer D. Klemisch ,  Jessica C. Pavia ,  Thomas Michael Henry ,  Clay J. Anderson ,  Bruce W. McCaul ,  Thomas Mac Winsemius ,  Eric K. Thorson

IPC: G01N21/39 ,  B64D37/32 ,  B64D37/02

CPC classification number: G01N21/39 ,  B64D37/32 ,  G01N2021/399 ,  G01N2201/0214 ,  G01N2201/0407

Abstract: An oxygen analysis system (OAS) for measuring, monitoring and recording oxygen concentration in aircraft fuel tanks. The OAS has a rack support structure installed in an aircraft cabin with a plurality of oxygen analyzer devices mounted in the rack support structure. Each oxygen analyzer device has an oxygen sensor to measure oxygen concentration in gas samples continuously drawn from sample locations in aircraft fuel tanks and at an aircraft NGS ASM exit. The OAS further has a plurality of valves, a supply of calibration gases, a supply of purge and operating gases, and a power distribution assembly, all coupled to the rack support structure. The OAS further has a transport tubing assembly, a plurality of fuel tank gas sampling ports, an NGS ASM exit gas sampling port, a drain manifold assembly, and a data acquisition and recording system having a user interface software to monitor and control the OAS.

Abstract translation: 用于测量，监测和记录飞机燃料箱中氧气浓度的氧分析系统（OAS）。 OAS具有安装在飞机机舱中的机架支撑结构，其具有安装在机架支撑结构中的多个氧分析仪装置。 每个氧气分析仪装置都有一个氧传感器来测量在飞机燃料箱和飞机NGS ASM出口处连续抽取的气体样品中的氧气浓度。 OAS还具有多个阀，校准气体的供应，吹扫和操作气体的供应以及全部联接到齿条支撑结构的动力分配组件。 OAS还具有运输管道组件，多个燃料箱气体采样端口，NGS ASM出口采气口，排水歧管组件以及具有用于监测和控制OAS的用户界面软件的数据采集和记录系统。

公开(公告)号：US20090189089A1

公开(公告)日：2009-07-30

申请号：US12419008

申请日：2009-04-06

Applicant: William Bedingham ,  Peter D. Ludowise ,  Barry W. Robole

Inventor： William Bedingham ,  Peter D. Ludowise ,  Barry W. Robole

IPC: G01N21/64 ,  G01B11/00 ,  A61N5/00 ,  G01N21/85

CPC classification number: F16K99/003 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2200/025 ,  B01L2300/021 ,  B01L2300/0806 ,  B01L2400/0409 ,  B01L2400/0677 ,  F16K99/0001 ,  F16K99/004 ,  F16K2099/0084 ,  G01N21/0332 ,  G01N21/07 ,  G01N21/359 ,  G01N21/6428 ,  G01N21/6452 ,  G01N35/00069 ,  G01N35/1097 ,  G01N2021/0325 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2035/00267 ,  G01N2035/00415 ,  G01N2035/0474 ,  G01N2201/0407 ,  G01N2201/0415 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/0833 ,  Y10T436/11 ,  Y10T436/111666

Abstract: Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device coupled to the data acquisition device. The detection device includes a rotating disk having a plurality of process chambers having a plurality of species that emit fluorescent light at different wavelengths. The device further includes a plurality of removable optical modules that are optically configured to excite the species and capture fluorescent light emitted by the species at different wavelengths. A fiber optic bundle coupled to the plurality of removable optical modules conveys the fluorescent light from the optical modules to a single detector. In addition, the device may control the flow of fluid in the disk by locating and selectively opening valves separating chambers by heating the valves with a laser.

Abstract translation: 描述了用于在实时PCR（聚合酶链式反应）中检测多种靶物种的技术。 例如，系统包括数据采集装置和耦合到数据采集装置的检测装置。 检测装置包括具有多个处理室的旋转盘，该多个处理室具有发射不同波长的荧光的多种物质。 该装置还包括多个可移除的光学模块，其被光学配置为激发物种并捕获由不同波长的物质发射的荧光。 耦合到多个可移除光学模块的光纤束将来自光学模块的荧光传送到单个检测器。 此外，该装置可以通过利用激光加热阀来定位和选择性地打开阀分离腔来控制盘中的流体流动。