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    Two-dimensional, anti-scatter grid and collimator designs, and its motion, fabrication and assembly
    82.
    发明专利
    Two-dimensional, anti-scatter grid and collimator designs, and its motion, fabrication and assembly 未知

    公开(公告)号：AU2090901A

    公开(公告)日：2001-06-18

    申请号：AU2090901

    申请日：2000-12-13

    Applicant: CREATV MICROTECH INC

    Inventor： TANG CHA-MEI

    IPC: G21K1/02 ,  G21K1/00

    Abstract: A grid, for use with electromagnetic energy emitting devices, includes at least metal layer, which is formed by electroplating. The metal layer includes top and bottom surfaces, and a plurality of solid integrated walls. Each of the solid integrated walls extends from the top to bottom surface and having a plurality of side surfaces. The side surfaces of the solid integrated walls are arranged to define a plurality of openings extending entirely through the layer. All of the walls can extend at 90° with respect to the top and bottom surfaces, or alternatively, some of the walls can extend at an angle other than 90° with respect to the top and bottom surfaces, such that the directions in which the walls extend all converge at a point in space at a predetermined distance from the front surface of the at least one layer. At least some of the walls also can include projections extending into the respective openings formed by the walls.

    Capture, identification and use of a new biomarker of solid tumors in body fluids
    87.
    发明专利
    Capture, identification and use of a new biomarker of solid tumors in body fluids 未知

    公开(公告)号：IL235885A

    公开(公告)日：2019-01-31

    申请号：IL23588514

    申请日：2014-11-24

    Applicant: CREATV MICROTECH INC

    Abstract: A new sensitive cell biomarker of solid tumors is identified in blood. This biomarker can be used to determine presence of carcinomas, rapid determination of treatment response, early detection of cancer, early detection of cancer recurrence, and may be used to determine therapy.

    Methods of using PD-L1 expression in treatment decisions for cancer therapy
    88.
    发明专利
    Methods of using PD-L1 expression in treatment decisions for cancer therapy 未知

    公开(公告)号：AU2017250284A1

    公开(公告)日：2018-11-08

    申请号：AU2017250284

    申请日：2017-04-14

    Applicant: CREATV MICROTECH INC

    Inventor： ADAMS DANIEL ,  TANG CHA-MEI

    IPC: C07K16/28 ,  C12N5/00 ,  G01N33/574

    Abstract: Methods of using detection of PD-L1 expression by circulating cancer cells in the screening, monitoring, treatment and diagnosis of cancer in subjects are disclosed. The methods are based on assaying one or more of circulating tumor cells (CTCs), epithelial to mesenchymal transition CTCs (EMTCTCs), cancer associated macrophage-like cells (CAMLs), and cancer associated vascular endothelial cells (CAVEs) isolated from a subject having cancer for PD-L1 expression.

    Use of circulating tumor cell mitotic index in cancer stratification and diagnostics
    90.
    发明专利
    Use of circulating tumor cell mitotic index in cancer stratification and diagnostics 未知

    公开(公告)号：AU2016267146A1

    公开(公告)日：2017-12-07

    申请号：AU2016267146

    申请日：2016-05-26

    Applicant: CREATV MICROTECH INC

    Inventor： ADAMS DANIEL ,  TANG CHA-MEI

    IPC: G01N33/50 ,  G01N33/574

    Abstract: Circulating tumor cells (CTCs) are associated with metastasis of malignant solid tumors in a patient. Presented here is evidence that CTCs exhibit cell cycle phase variability and that there is a strong correlation between the number of CTCs in a mitotic cell cycle phase and the prospects for long term survival of the subject from which the cells were obtained. Also presented herein are methods of determining the mitotic cell cycle phase of CTCs from a patient having cancer and using the information in grading malignant solid tumors and predicting the likelihood of survival of the patient.

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