公开(公告)号：US20240000053A1

公开(公告)日：2024-01-04

申请号：US18254484

申请日：2021-11-02

Applicant: JTEKT CORPORATION ,  Tokushima University

Inventor： Yasuhiro MURATA ,  Akihiro TAKAZATO ,  Shigekazu KAWAI ,  Nozomu MIURA ,  Takahito WATANABE ,  Taro MITO

IPC: A01K67/033

CPC classification number: A01K67/033

Abstract: There is provided a rearing apparatus including a hatching area that holds eggs of organisms to be reared and accommodates the organisms hatched from the eggs, and a rearing area that is defined in an area larger than the hatching area at a position different from the hatching area and in which the organisms are reared. The present disclosure provides a rearing apparatus that can implement high-density and large-scale rearing by effectively utilizing areas.

公开(公告)号：US20230022585A1

公开(公告)日：2023-01-26

申请号：US17780315

申请日：2020-11-27

Applicant: TOKUSHIMA UNIVERSITY

Inventor： Mikito YASUZAWA ,  Tsubasa MIKI ,  Yukihiro ARAKAWA ,  Yasushi IMADA ,  Hitoshi MATSUKI

IPC: C08F20/36 ,  C08J5/18 ,  A61L27/34 ,  C08F20/18 ,  A61L27/16

Abstract: An object is to provide a zwitterionic compound having an excellent protein adsorption inhibitory effect. The zwitterionic compound is a polymer comprising a unit represented by the following formula (1): wherein R1 is a hydrogen atom or a methyl group, R2 is OH or O−, X1 is —O— or —N(Q1)-, Q1 is a hydrogen atom or a C1-6 alkyl group, m is an integer of 1 to 12, and n is an integer of 1 to 4.

公开(公告)号：US20220364101A1

公开(公告)日：2022-11-17

申请号：US17623302

申请日：2020-07-03

Applicant: Tokushima University

Inventor： Kohji Itoh ,  Jun Tsukimoto

IPC: C12N15/52 ,  A61P3/00 ,  C12N15/86 ,  C12N9/48

Abstract: Provided are a modified-type neuraminidase, a gene encoding the modified-type neuraminidase, a combination of the modified-type neuraminidase and cathepsin A, a combination of the gene encoding the modified-type neuraminidase and a gene encoding cathepsin A, a vector including said genes, and a pharmaceutical composition containing same. The pharmaceutical composition can be used for the therapy of lysosomal storage disease.

公开(公告)号：US20220213576A1

公开(公告)日：2022-07-07

申请号：US17607397

申请日：2020-09-24

Applicant: TANAKA KIKINZOKU KOGYO K.K. ,  TOKUSHIMA UNIVERSITY

Inventor： Michimasa OKUBO ,  Kenji GOTO ,  Kunihiro TANAKA ,  Kojiro SHIRAISHI ,  Kunihiro SHIMA ,  Yuya KATO ,  Kenichi HAMADA ,  Eiichi HONDA ,  Emi TAKEGAWA

IPC: C22C5/02 ,  C22C1/02

Abstract: The present invention relates to a medical Au—Pt—Pd alloy including Au, Pt, Pd, and inevitable impurities. The alloy has an alloy composition inside a polygon (A1-A2-A3-A4-A5-A6) surrounded by straight lines connected at point A1 (Au: 37.9 atom %, Pt: 0.1 atom %, and Pd: 62 atom %), point A2 (Au: 79.9 atom %, Pt: 0.1 atom %, and Pd: 20 atom %), point A3 (Au: 79.9 atom %, Pt: 20 atom %, and Pd: 0.1 atom %), point A4 (Au: 69.9 atom %, Pt: 30 atom %, and Pd: 0.1 atom %), point A5 (Au: 49 atom %, Pt: 30 atom %, and Pd: 21 atom %), and point A6 (Au: 39 atom %, Pt: 40 atom %, and Pd: 21 atom %) in a Au—Pt—Pd ternary state diagram. The metal structure of the alloy is optimized, and the metal structure is close to a single-phase structure, and has little precipitation of a Au-rich phase and a Pt-rich phase different in composition from a mother phase.

公开(公告)号：US11377506B2

公开(公告)日：2022-07-05

申请号：US16762221

申请日：2018-11-14

Applicant: TOKUSHIMA UNIVERSITY ,  SEKISUI CHEMICAL CO., LTD.

Inventor： Koichi Ute ,  Tomohiro Hirano ,  Miyuki Oshimura ,  Yasunari Kusaka ,  Yohei Nishimura ,  Misaki Senoo

IPC: C08F8/14 ,  C08F216/06 ,  C08F218/08

Abstract: The present invention provides a vinyl alcohol-vinyl acetate copolymer having excellent solubility and capable of providing a film having high flexibility, high mechanical strength, and high adhesion, and a method for producing a vinyl alcohol-vinyl acetate copolymer. Provided is a vinyl alcohol-vinyl acetate copolymer including a unit of vinyl alcohol and a unit of vinyl acetate, the vinyl alcohol-vinyl acetate copolymer having a triad unit chain ratio TOO of 7.5 or less, where the triad unit chain ratio TOO is obtained using the following formula (1): [ Math . ⁢ 1 ] T OO = [ Vac ⁢ ⁢ content ] × [ OOO ⁢ ⁢ proportion ] × 2 [ VOH ⁢ ⁢ content ] × [ AOO ⁢ ⁢ proportion ] ( 1 ) wherein the VOH content ratio represents the amount of the unit of vinyl alcohol, the Vac content ratio represents the amount of the unit of vinyl acetate, the OOO proportion represents the proportion of a triad OOO, and the AOO proportion represents the proportion of a triad AOO.

公开(公告)号：US20210363520A1

公开(公告)日：2021-11-25

申请号：US16640521

申请日：2018-08-20

Applicant: Tokushima University

Inventor： Keishi Osakabe ,  Yuriko Osakabe

IPC: C12N15/11 ,  C12N9/22 ,  C12N15/10

Abstract: Provided is a method for targeting a target nucleotide sequence. The method includes introducing, into a cell: (i) CRISPR type I-D related proteins Cas5d, Cas6d, and Cas7d, or nucleic acids encoding these proteins; and (ii) a guide RNA which includes a sequence complementary to said target nucleotide sequence and common repetitive sequences derived from CRISPR gene locus before and after said complementary sequence, or a DNA, encoding said guide RNA.

公开(公告)号：US20210246560A1

公开(公告)日：2021-08-12

申请号：US17272765

申请日：2020-06-04

Applicant: CHEMICAL DENSHI CO., LTD. ,  Tokushima University

Inventor： Shoichi YAMADA ,  Toshio HYUGA ,  Hisao NEMOTO

IPC: C23F11/12 ,  C07D319/06 ,  C07D317/20 ,  C07C327/22 ,  C23F11/16

Abstract: The objective of the present invention is to provide a hydrophilic metal surface treatment agent by which a water-repellent property can be given to a metal surface with suppressing a corrosion and a discolorment of the metal, a method for treating a surface of a metal by using the hydrophilic metal surface treatment agent, a synthetic intermediate compound of a branched glycerol derivative as an active ingredient of the hydrophilic metal surface treatment agent, and a method for efficiently producing the synthetic intermediate compound. The hydrophilic metal surface treatment agent of the present invention is characterized in comprising the branched glycerol derivative represented by the following formula (I) as an active ingredient. wherein R1 is a hydrocarbon group having a carbon number of 10 or more and 30 or less, X is S or a carbonyl group, Y is an n +1 valent linker group, n is an integer of 1 or more and 5 or less.

公开(公告)号：US10928303B2

公开(公告)日：2021-02-23

申请号：US16320002

申请日：2017-07-25

Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

Inventor： Yoshihiro Deguchi ,  Takashi Fukawa ,  Taiki Hattori ,  Masaaki Nagase ,  Kazuteru Tanaka ,  Kouji Nishino ,  Nobukazu Ikeda

IPC: G01N21/59 ,  G01N21/05 ,  G01N21/03 ,  G01N21/33

Abstract: A concentration measuring device includes a measuring cell having a flow passage and a translucent window, a light source for emitting light to the measuring cell through the window, a reflective member for reflecting light propagating through the measuring cell to the window, a light detector for detecting the light exiting from the window, a calculation part for calculating the concentration of the fluid on the basis of a detection signal from the light detector, and an optical device for guiding the light from the light source to the window and guiding the light from the window to the light detector.

公开(公告)号：US20190271636A1

公开(公告)日：2019-09-05

申请号：US16320002

申请日：2017-07-25

Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

Inventor： Yoshihiro DEGUCHI ,  Takashi FUKAWA ,  Taiki HATTORI ,  Masaaki NAGASE ,  Kazuteru TANAKA ,  Kouji NISHINO ,  Nobukazu IKEDA

IPC: G01N21/05 ,  G01N21/59 ,  G01N21/03

Abstract: A concentration measuring device includes a measuring cell having a flow passage and a translucent window, a light source for emitting light to the measuring cell through the window, a reflective member for reflecting light propagating through the measuring cell to the window, a light detector for detecting the light exiting from the window, a calculation part for calculating the concentration of the fluid on the basis of a detection signal from the light detector, and an optical device for guiding the light from the light source to the window and guiding the light from the window to the light detector.

公开(公告)号：US10324029B2

公开(公告)日：2019-06-18

申请号：US15748261

申请日：2016-08-09

Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

Inventor： Yoshihiro Deguchi ,  Masaaki Nagase ,  Michio Yamaji ,  Nobukazu Ikeda ,  Kouji Nishino ,  Masayoshi Kawashima ,  Kazuteru Tanaka

IPC: G01N21/31 ,  G01N21/33 ,  G01J3/42 ,  G01N21/59 ,  G01N21/27 ,  G01J3/10 ,  G01J3/28 ,  G01J3/433 ,  G01J3/02 ,  G01N21/3504 ,  G01J1/42

Abstract: A concentration measurement device including at least one light source; a measurement cell for containing a fluid to be measured; a splitter for dividing light from the light source into incident light being incident into the measurement cell and non-incident light not being incident into the measurement cell; a transmitted-light detector for detecting transmitted light that is the incident light having passed through the measurement cell; a non-incident light detector for detecting the non-incident light; and an arithmetic part for correcting a detection signal of the transmitted-light detector using a detection signal of the non-incident light detector.