Abstract:
본 발명은 피부 질환의 광학 진단 및 치료를 위한 장치, 광원 시스템 및 방법에 관한 것으로서, 형광 및 백색광을 동시에 사용하여 피부상태를 정밀하게 평가함으로써 피부 진단의 효과가 향상될 수 있고, 피부의 동일 부위에서 형광 진단 및 광역학 치료를 동시에 수행할 수 있는 피부 질환의 광학 진단 및 치료를 위한 장치, 광원 시스템 및 방법에 관한 것이다. 상기한 목적을 달성하기 위한 본 발명의 광학 진단 및 치료 장치는, 전면에 피부 부위에 밀착되는 시야 홀이 형성된 케이스와, 상기 케이스 내부에서 시야 홀을 통해 백색광을 조사하도록 설치된 백색광원과, 상기 케이스 후방으로 설치된 디지털 컬러 TV 카메라를 포함하여 구성되고, 상기 케이스 내부에서 시야 홀에 밀착된 피부 부위로 백색광 및 형광 여기광을 모두 조사할 수 있도록 구성되며, 상기 디지털 컬러 TV 카메라가 피부 부위로부터 광을 수집하여 생성한 영상신호를 출력하도록 구성된 카메라 헤드와; 상기 카메라 헤드의 케이스와 광 전송이 가능한 광 가이드로 연결되어서 피부 부위에 조사되는 형광 여기광을 상기 카메라 헤드에 제공하는 광원 시스템과; 상기 카메라 헤드로부터 영상신호를 전송받아 처리 및 분석, 저장하고, 모니터를 통해 상기 디지털 컬러 TV 카메라에 의해 획득된 백색광에 의한 컬러 영상 및 여기광에 의한 형광 영상을 디스플레이하거나 이들의 합성 영상을 디스플레이하며, 상기 카메라 헤드와 광원 시스템의 작동 전반을 제어하는 영상 처리 및 분석 시스템;을 포함하여 구성된다. 광학, 광역학, 진단, 치료, 형광, 백색광, PDT
Abstract:
An apparatus, a light source system and a method for photo-diagnosis and a photo dynamic therapy of a skin disease are provided to improve an effect of a skin diagnosis by simultaneously using a fluorescent shape of an excitation light and a color image of a white light and precisely estimating a skin state. An apparatus for photo-diagnosis and a photo dynamic therapy of a skin disease includes a camera head(100), a light source system(200), and an image processing and analyzing system(300). A case(110) has a visual hole which is contacted with a skin part. A white light source(130) is installed inside the case to illuminate a white light through the visual hole. A digital color TV camera(120) is installed on a rear part of the case. The camera head is configured to illuminate a white light, a fluorescent excitation light, and a treat light to the skin part which is contacted with the visual hole. The digital color TV collects a light from the skin part and outputs a generated image signal. The light source system is coupled to the case of the camera head by a light guide, and provides the fluorescent excitation light, the treat light and the white light to the camera head. The image processing and analyzing system receives, processes, analyzes and stores the image signal from the camera head. The image processing and analyzing system displays the color image by the white light acquired by the digital color TV camera and the fluorescent image by the treat light and the excitation light, or displays a mixed image of them. The image processing and analyzing system controls an operation of the camera head and the light source system.
Abstract:
An optical diagnosis apparatus for improving illumination uniformity is provided to observe quantitatively a target part by illuminating uniform light to the target part. An optical diagnosis apparatus includes a plurality of light emitting diodes as white light sources and a plurality of light emitting diodes as phosphor excitation light sources in order to perform a white light observation process and a phosphor diagnosis process for a skin part. The light emitting diodes as the white light sources and the light emitting diodes as the phosphor excitation light sources are installed in a case of an image pickup case. The light emitting diodes as the phosphor excitation light sources are installed at a predetermined illumination center axis angle on the basis of an image pickup optical axis in order to illuminate an assigned individual area of a target skin part.
Abstract:
A light source for a fluorescence diagnosis and a photodynamic therapy is provided to improve a therapy effect by increasing a light intensity in a short-wave region during a PDT(Photodynamic Therapy) process. A light source includes plural sources(10), a light path coupler(20), a first filter(30), an optical guide(50), and a switch(41). The sources provide various beams with different wavelength ranges. The light path coupler couples the light from the sources to an inlet surface of the optical guide. The first filter is integrated on a single case with the light path coupler and selectively passes the irradiated beam according to the wavelength ranges. The optical guide delivers the light to a diagnosis position. The switch selects one of the sources and changes a selection condition of the sources. The switch is controlled by using a remote controller.
Abstract:
본 발명은 일반적인 바이오칩을 그대로 사용하여 측정하여도, 광학적 잡음을 현저히 감소시킨 형광 이미지의 검출이 가능하고, 간단한 구조로 저렴한 단가의 제작이 가능하며, 바이오칩을 신속하게 대량 측정할 수 있도록 하는 바이오칩 측정 장치 및 방법을 제안한다. 본 발명의 바이오칩 측정 장치는, 얇은 평행 육면체 형태인 기판 상의 일면에 하나 이상의 바이오 시편이 배열된 바이오칩으로부터 방출되는 형광을 관측하기 위한 바이오칩 측정 장치이며, 상기 바이오칩을 지지하는 바이오칩 홀더; 상기 바이오칩의 상기 투명 기판 측면으로 광을 입사시켜, 입사된 광이 상기 기판 내부에서 전반사되어 상기 바이오 시편 부근에 도달하도록 하는 여기광 공급부; 및 상기 기판 내부에서 전반사된 광에 의하여 상기 바이오 시편으로부터 발생되는 형광을 채집하여 검출하는 형광 검출부를 포함하여 구성된다. 바이오칩, 형광, 여기광, DNA 칩, 측정 장치
Abstract:
This present invention relates to a fluorescence endoscope apparatus, developed for diagnosing various illnesses within a body, especially for diagnosing a tumor inflamed region; and an application method of the same. The purpose of this invention is to enhance the accuracy of the examination. The fluorescence light endoscope apparatus in accordance with the present invention is comprised of an endoscope probe; a multiple light source that provides illumination light or excitation light of short wavelength onto a diagnostic region; a color CCD camera and a high sensitive monochromatic CCD camera placed on the back of an endoscope ocular lens; a reference test sample; a computer; and a monitor. The method of the present invention embodies a preliminary correction of the fluorescence endoscope apparatus of the present invention in accordance with the reference test sample; a general endoscopy using the illumination light, and an image observation and examination of the same diagnostic region using the fluorescence light and the reflected excitation light simultaneously; an auto-correction of brightness and unevenness of the fluorescence light images of the diagnostic region according to the reference test sample data; an evaluation of the brightness of the fluorescence light in the diagnosis region; storing numerical data that characterizing images and brightness of the fluorescence light in the diagnosis region; and storing image collected via two cameras as digital video clips.
Abstract:
PURPOSE: A gas-forming mixture used in gas-heat-chemical treatment of phosphate glass is provided, which has much improved thermal impact resistance by using NH4Cl and oxides compared with conventional gas-forming mixture using NH4Cl. CONSTITUTION: The gas-forming mixture is characterized by the following components of; (i) NH4Cl; (ii) a compound containing at least one oxide-such as kaolinite(Al2O3.2SiO2.2H2O) or aluminum borate(Al2O3.B2O3), or one oxide of III, IV and V groups such as Ga2O3, Fe2O3, Sb2O3, CeO2, SiO2, TiO2, Nb2O5 or Ta2O5, wherein the weight ratio of NH4Cl to oxides is 98.0-99.3 : 0.7-2.0.
Abstract translation:目的:提供用于磷酸盐玻璃的气体热化学处理的气体形成混合物,与使用NH 4 Cl的常规气体形成混合物相比,使用NH 4 Cl和氧化物具有大大改善的耐热冲击性。 构成:气体形成混合物的特征在于以下组分: (i)NH 4 Cl; (ii)含有至少一种氧化物的化合物,例如高岭石(Al 2 O 3·2·SiO 2·2H 2 O)或硼酸铝(Al 2 O 3·B 2 O 3),或III,IV和V族的一种氧化物,例如Ga 2 O 3,Fe 2 O 3,Sb 2 O 3,CeO 2, SiO 2,TiO 2,Nb 2 O 5或Ta 2 O 5,其中NH 4 Cl与氧化物的重量比为98.0-99.3:0.7-2.0。
Abstract:
This is for composition of low thermal expansive-machinible glass-ceramic. The compositions comprises 5-18 wt.% of K2O, 2-8 wt.% of Li2O, 2-9 wt.% of TiO2, 9-23 wt.% of Al2O3, 50-70 wt.% of SiO2, and 4-10 wt.% of F (or pref. 5-10 wt.% of K2O, 5-8 wt.% of Li2, 2-5 wt.% of TiO2, 13-25 wt.% of Al2O3, 50-70 wt.% of SiO2, and 4-10 wt.% of F). A weighted mixture is melted for 1-4 hr at 1300-1450 deg.C and forming glass in preheated mold, and the crystallized glass is made by heat treatment at 800-1050 deg.C for 1-8 hr..