公开(公告)号：EP3356485B1

公开(公告)日：2020-08-05

申请号：EP16852358.7

申请日：2016-09-26

Applicant: 3M Innovative Properties Company

Inventor： YOUNG, Alexi J. ,  RASMUSSEN, Jerald K.

IPC: A61L26/00 ,  A61L15/60 ,  C09J11/04 ,  C08J3/075 ,  C08L33/10 ,  C08L33/26

公开(公告)号：EP2928900B1

公开(公告)日：2019-01-02

申请号：EP13860076.2

申请日：2013-11-20

Applicant: 3M Innovative Properties Company

Inventor： GRIESGRABER, George W. ,  FITZSIMONS, Robert T. Jr. ,  HANGGI, Douglas A. ,  NAKAMURA, Masayuki ,  RASMUSSEN, Jerald K.

IPC: B01J20/28 ,  B01J20/10 ,  B01J20/22 ,  B01J20/32 ,  C07F7/10 ,  C07C279/04 ,  B01J2/08 ,  G01N1/40 ,  C07F7/18 ,  B01D15/00 ,  B01D24/00

公开(公告)号：EP3365095A1

公开(公告)日：2018-08-29

申请号：EP16788850.2

申请日：2016-10-11

Applicant: 3M Innovative Properties Company

Inventor： HESTER, Jonathan F. ,  CASTRO FORERO, Angelines A. ,  JELLUM, Gregory M. ,  RASMUSSEN, Jerald K. ,  SESHADRI, Kannan ,  WALLER, Clinton P., Jr.

IPC: B01D67/00 ,  B01D69/10 ,  B01D71/40 ,  B01D71/78

CPC classification number: B01D69/125 ,  B01D63/10 ,  B01D63/14 ,  B01D67/009 ,  B01D69/02 ,  B01D69/10 ,  B01D71/40 ,  B01D71/78 ,  B01D2323/385 ,  B01D2325/16 ,  B01D2325/42 ,  C07K1/34

Abstract: Described herein is a filtration media comprising: (i) a first filtration medium comprising an anion exchange nonwoven substrate, wherein the anion exchange nonwoven substrate comprises a plurality of quaternary ammonium groups; and (ii) a second filtration medium comprising a functionalized microporous membrane wherein the functionalized microporous membrane comprises a plurality of guanidyl groups; wherein the first filtration medium is positioned upstream of the second filtration medium.

公开(公告)号：EP3274069A1

公开(公告)日：2018-01-31

申请号：EP16717497.8

申请日：2016-03-17

Applicant: 3M Innovative Properties Company

Inventor： VAIL, Andrew W. ,  RASMUSSEN, Jerald K. ,  SCHMIDT, John J. ,  OZCAM, Ali E. ,  HESTER, Jonathan F. ,  JELLUM, Gregory M.

IPC: B01D37/00 ,  C12N5/00 ,  C12N15/00 ,  G01N30/00

Abstract: A method of purifying a biological composition includes: disposing loose cationic ligand-functionalized staple fibers and a biological composition within a mixing volume of a vessel; agitating the biological composition and the loose cationic ligand-functionalized staple fibers while they are in intimate contact with each other within the mixing volume to provide modified fibers and a purified biological composition; and separating at least a portion of the purified biological composition from the modified fibers and any loose cationic ligand-functionalized staple fibers with which it is in contact. The loose cationic ligand-functionalized staple fibers have a modified surface layer comprising a grafted acrylic polymer comprising 10 to 100 percent by weight of a cationically-ionizable monomer unit. An article for purifying a biological composition includes: a vessel having a mixing volume disposed therein; and the loose cationic ligand-functionalized staple fibers disposed within the mixing volume.

公开(公告)号：EP3052556A1

公开(公告)日：2016-08-10

申请号：EP14851051.4

申请日：2014-09-25

Applicant: 3M Innovative Properties Company

Inventor： RASMUSSEN, Jerald K. ,  BOTHOF, Catherine A. ,  GRIESGRABER, George W. ,  COLAK ATAN, Semra ,  HEMBRE, James I. ,  FITZSIMONS, Robert T. Jr.

IPC: C08J7/18 ,  C07K1/34 ,  B01J20/26 ,  G01N33/52 ,  B01D71/44 ,  C07F9/38 ,  C07F5/02

CPC classification number: G01N1/405 ,  B01D67/0093 ,  B01D71/44 ,  B01D71/52 ,  B01D71/56 ,  B01D2323/345 ,  B01D2323/38 ,  B01D2325/14 ,  B01D2325/16 ,  B01J20/261 ,  B01J20/28038 ,  B01J20/321 ,  B01J20/3242 ,  B01J20/3251 ,  B01J20/3253 ,  B01J20/327 ,  C07F9/3808 ,  C07K1/18 ,  C07K1/34 ,  C08J7/18 ,  C08J2377/00 ,  G01N1/4077 ,  G01N33/544 ,  G01N2001/4088 ,  G01N2333/924

Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.

公开(公告)号：EP3010883A1

公开(公告)日：2016-04-27

申请号：EP14814506.3

申请日：2014-06-12

Applicant: 3M Innovative Properties Company

Inventor： RASMUSSEN, Jerald K. ,  GRIESGRABER, George W. ,  HEMBRE, James I.

IPC: C07C277/08 ,  C07C277/02 ,  C07C279/12 ,  C08G69/00 ,  C08G73/00 ,  C09D177/00 ,  C09D179/02 ,  B01D71/60 ,  B01J20/26 ,  D06M14/30 ,  G01N33/53

CPC classification number: C07C277/08 ,  B01J20/261 ,  B01J20/28033 ,  B01J20/327 ,  C07C277/02 ,  C07C279/12 ,  C08F26/00 ,  C08F120/36 ,  C08F126/02 ,  C08F220/36 ,  C09D4/00 ,  C09D133/14 ,  D06M14/30 ,  G01N1/405 ,  G01N33/53 ,  G01N33/545 ,  C07C279/08

Abstract: A process for preparing guanidino-functional, free radically polymerizable compounds comprises (a) combining (1) an amine compound comprising (i) at least one primary aliphatic amino group and (ii) at least one secondary aliphatic amino group, primary aromatic amino group, or secondary aromatic amino group, and (2) a guanylating agent; (b) allowing or inducing reaction of the amine compound and the guanylating agent to form a guanylated amine compound; (c) combining (1) the guanylated amine compound, and (2) a reactive monomer comprising (i) at least one ethylenically unsaturated group and (ii) at least one group that is reactive with an amino group; and (d) allowing or inducing reaction of the guanylated amine compound and the reactive monomer to form a guanidino-functional, free radically polymerizable compound.

Abstract translation: 制备胍基官能的，可自由基聚合的化合物的方法包括（a）将（1）胺化合物与（1）至少一个伯脂族氨基和（ii）至少一个仲脂族氨基，伯芳族氨基 ，或仲芳族氨基，和（2）鸟苷酰化剂; （b）使胺化合物和鸟苷酰化试剂反应或引发反应以形成鸟苷酰胺化合物; （c）将（1）脒基胺化合物与（2）包含（i）至少一个烯属不饱和基团和（ii）至少一个与氨基反应的基团的反应性单体组合; （d）使脒化的胺化合物和反应性单体反应以形成胍基官能的，可自由基聚合的化合物。

公开(公告)号：EP1373167B1

公开(公告)日：2015-12-09

申请号：EP02715021.8

申请日：2002-02-28

Applicant: 3M Innovative Properties Company

Inventor： RASMUSSEN, Jerald K. ,  KREPSKI, Larry R.

IPC: C07H21/04 ,  C07K1/04 ,  C40B50/14

CPC classification number: C40B50/14 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00527 ,  B01J2219/00596 ,  C07B2200/11 ,  C07H21/04 ,  C07K1/042

公开(公告)号：EP2928900A1

公开(公告)日：2015-10-14

申请号：EP13860076.2

申请日：2013-11-20

Applicant: 3M Innovative Properties Company

Inventor： GRIESGRABER, George W. ,  FITZSIMONS, Robert T. Jr. ,  HANGGI, Douglas A. ,  NAKAMURA, Masayuki ,  RASMUSSEN, Jerald K.

IPC: C07F7/10 ,  C07C279/04 ,  B01J2/08

CPC classification number: C07F7/1804 ,  B01D15/00 ,  B01D24/00 ,  B01J20/103 ,  B01J20/22 ,  B01J20/28004 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/286 ,  B01J20/289 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3244 ,  B01J20/3293 ,  B01J2220/80 ,  C07F7/1872 ,  C07F7/1892 ,  C12M25/16 ,  G01N1/405

Abstract: Guanidine-functionalized particles and methods of making and using such particles.

公开(公告)号：EP2855010A1

公开(公告)日：2015-04-08

申请号：EP13726995.7

申请日：2013-05-23

Applicant: 3M Innovative Properties Company

Inventor： BOTHOF, Catherine A. ,  GRIESGRABER, George W. ,  HEMBRE, James I. ,  RASMUSSEN, Jerald K.

IPC: B01J20/26 ,  B01D67/00 ,  B01D71/56 ,  C09D179/02 ,  G01N33/543

CPC classification number: B01D71/78 ,  B01D71/40 ,  B01D71/56 ,  B01D71/76 ,  B01D2323/30 ,  B01D2323/385 ,  B01D2325/12 ,  B01J20/261 ,  B01J20/264 ,  B01J20/321 ,  B01J20/3282 ,  B01J20/3293 ,  B01J20/3297 ,  C08F255/02 ,  C08F283/04 ,  C08G69/10 ,  C08G69/48 ,  C08G73/0206 ,  C08G73/022 ,  C08G73/028 ,  C08J7/18 ,  C08J2323/06 ,  C08J2323/12 ,  C08J2377/00 ,  C08J2433/14 ,  C09D177/04 ,  C09D179/02 ,  G01N33/54393 ,  G01N33/545

Abstract: The present invention relates to an article comprising: a) a substrate, and b) grafted to the surface of the substrate a (co)polymer comprising interpolymerized guanidinyl-functional (meth)acryloyl monomer units of the formula: or wherein R 1 is H or C 1 -C 4 alkyl; R 2 is a (hetero)hydrocarbyl group; each R 3 is independently H or hydrocarbyl; R 4 is H, C 1 -C 12 alkyl or -N(R 3 ) 2 ; R 5 is H or hydrocarbyl; X 1 is -O- or -NR 3 -; o is 0 or 1, and n is 1 or 2.

Abstract translation: 描述了胍基配体官能化聚合物，其制备方法以及带有配体官能聚合物接枝涂层的基材。 在接近或低于生物材料的pI's的pH下，接枝聚合物对结合中性或带负电荷的生物材料（例如细胞，细胞碎片，细菌，孢子​​，病毒，核酸，内毒素和蛋白质）具有必需的亲和力。

公开(公告)号：EP2794052A1

公开(公告)日：2014-10-29

申请号：EP12809063.6

申请日：2012-12-17

Applicant: 3M Innovative Properties Company

Inventor： NAKAMURA, Masayuki ,  SUGIYAMA, Naota ,  ZOOK, Cynthia D. ,  AMOS, Stephen E. ,  RASMUSSEN, Jerald K. ,  GRYSKA, Nicole M.

IPC: B01D15/38 ,  G01N33/543 ,  G01N33/552

CPC classification number: G01N1/405 ,  B01D15/3804 ,  B01J20/28004 ,  B01J20/28021 ,  B01J20/281 ,  B01J20/289 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3261 ,  B01J20/3291 ,  B01J2220/82 ,  C07K1/16 ,  C12N15/1006 ,  C12N15/101

Abstract: A composition for use in bioseparation. The composition includes a plurality of hollow particles having a siliceous surface. The composition further includes a surface-modifying agent bonded to the hollow particles. The surface-modifying agent includes a binding segment and a reactive segment. The binding segment includes a silyl group and the reactive segment includes a reactive nitrogen group.

Abstract translation: 用于生物分离的组合物。 该组合物包括具有硅质表面的多个中空颗粒。 该组合物还包括与中空颗粒结合的表面改性剂。 表面改性剂包括结合段和反应性区段。 结合段包括甲硅烷基，反应性区段包括反应性氮基团。