公开(公告)号：WO2014099166A2

公开(公告)日：2014-06-26

申请号：PCT/US2013/068859

申请日：2013-11-07

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： LIU, Zhiqiang ,  PAN, Long ,  CONVERY, Joseph ,  YUAN, Shaotang ,  TRIVEDI, Harsh M.

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K8/447 ,  A61K2800/58 ,  A61K2800/5922 ,  A61K2800/882 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

Abstract translation: 提供了组合物，例如口服和个人护理产品，其包含（i）锌（氨基酸或三烷基甘氨酸）卤化物络合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备和 使用相同

公开(公告)号：WO2014099039A3

公开(公告)日：2014-06-26

申请号：PCT/US2013/050845

申请日：2013-07-17

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  YUAN, Shaotang ,  MATTAI, Jairajh ,  MASTERS, James G.

IPC: A61K8/27 ,  A61K8/44 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/10

Abstract: A method for indicating release of an antibacterial agent or for indicating an amount of time for cleansing skin with an aqueous cleansing composition comprising a surfactant and a zinc X halide complex, wherein X is an amino acid or trimethylglycine, wherein the method comprises washing skin with the cleansing composition and water for a time until the zinc X halide complex precipitates from the aqueous cleansing composition.

公开(公告)号：WO2014098822A1

公开(公告)日：2014-06-26

申请号：PCT/US2012/070506

申请日：2012-12-19

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  YUAN, Shaotang ,  PILCH, Shira ,  MASTERS, James, G. ,  LIU, Zhiqiang

IPC: A61K8/27 ,  A61K8/44 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/21 ,  A61K8/27 ,  A61K8/442 ,  A61K2800/58 ,  A61Q11/00

Abstract: Disclosed herein are mouthwashes comprising a complex of a zinc ion source acid. Methods of making and using the compositions are also provided.

Abstract translation: 本文公开了包含锌离子源酸的络合物的漱口水。 还提供了制备和使用组合物的方法。

公开(公告)号：WO2014098821A1

公开(公告)日：2014-06-26

申请号：PCT/US2012/070505

申请日：2012-12-19

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  YUAN, Shaotang ,  MATTAI, Jairajh ,  MASTERS, James, G.

IPC: A61K8/27 ,  A61K8/44 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/10

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K2800/262 ,  A61K2800/45 ,  A61K2800/58 ,  A61Q17/005 ,  A61Q17/04 ,  A61Q19/10

Abstract: A method for indicating release of an antibacterial agent or for indicating an amount of time for cleansing skin with an aqueous cleansing composition comprising a surfactant and a zinc X halide complex, wherein X is an amino acid or trimethylglycine, wherein the method comprises washing skin with the cleansing composition and water for a time until the zinc X halide complex precipitates from the aqueous cleansing composition.

Abstract translation: 一种用于指示使用包含表面活性剂和锌X卤化物配合物的水性清洁组合物来表示抗菌剂释放或用于指示用于清洁皮肤的时间量的方法，其中X是氨基酸或三甲基甘氨酸，其中所述方法包括用 清洁组合物和水一直到锌X卤化物复合物从水性清洁组合物中沉淀出来。

公开(公告)号：WO2013158077A1

公开(公告)日：2013-10-24

申请号：PCT/US2012/033926

申请日：2012-04-17

Applicant: COLGATE-PALMOLIVE COMPANY ,  YUAN, Shaotang ,  PAN, Long ,  VAUGHN, John ,  PAPPAS, Iraklis ,  MASTERS, James

Inventor： YUAN, Shaotang ,  PAN, Long ,  VAUGHN, John ,  PAPPAS, Iraklis ,  MASTERS, James

IPC: C01F7/00 ,  C01F7/56 ,  A61K8/26 ,  A61Q15/00 ,  C01G25/00

CPC classification number: A61K8/26 ,  A61K8/28 ,  A61K2800/80 ,  A61Q15/00 ,  C01F7/002 ,  C01F7/56 ,  C01G25/006

Abstract: A method of making aluminum salt compositions using a combination of a basic organic buffer with a source of alkaline earth metal ions. This selection of basic organic buffer provides for a lower alkaline earth metal salt content in the composition made by the method.

Abstract translation: 一种使用碱性有机缓冲液与碱土金属离子源的组合制备铝盐组合物的方法。 碱性有机缓冲液的选择提供了通过该方法制备的组合物中较低的碱土金属盐含量。

公开(公告)号：WO2012148480A1

公开(公告)日：2012-11-01

申请号：PCT/US2011/066012

申请日：2011-12-20

Applicant: COLGATE-PALMOLIVE COMPANY ,  VAUGHN, John ,  PAPPAS, Iraklis ,  PAN, Long

Inventor： VAUGHN, John ,  PAPPAS, Iraklis ,  PAN, Long

IPC: C01F7/00 ,  A61K8/26 ,  A61Q15/00 ,  C01G25/00 ,  C01F7/56

CPC classification number: A61K8/26 ,  A61K8/19 ,  A61K8/20 ,  A61K8/28 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/58 ,  A61Q15/00 ,  C01F7/002 ,  C01F7/56 ,  C01P2002/86 ,  C01P2002/87

Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27 Al NMR that is present in a relative abundance on a 27 Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27 Al NMR. Also, disclosed are methods of making the antiperspirant active.

Abstract translation: 一种止汗活性组合物，其包含铝盐，所述铝盐（i）的铝与氯化物的摩尔比为0.3:1至3:1; 和（ii）具有通过27Al NMR在76ppm处可检测到的聚羟基氧化铝阳离子的种类，其在27Al NMR光谱仪上的相对丰度存在，其大于通过27Al NMR可检测的任何其它聚羟基氧代铝阳离子。 此外，公开了使止汗剂活性的方法。

公开(公告)号：WO2011087702A3

公开(公告)日：2011-07-21

申请号：PCT/US2010/060633

申请日：2010-12-16

Applicant: COLGATE-PALMOLIVE COMPANY ,  FITZGERALD, Michael C. ,  PAN, Long ,  PAPPAS, Iraklis ,  KILPATRICK-LIVERMAN, LaTonya

Inventor： FITZGERALD, Michael C. ,  PAN, Long ,  PAPPAS, Iraklis ,  KILPATRICK-LIVERMAN, LaTonya

IPC: A61Q15/00 ,  A61K8/26 ,  A61K8/42 ,  A61K8/44

Abstract: An aqueous antiperspirant/deodorant composition comprising: (a) at least one active chosen from an antiperspirant active and a deodorant active, (b) a mixture comprising at least one basic compound chosen from a basic amide and a basic amine and a counterpart material for the basic amide and/or basic amine, and (c) at least 10 weight% water. Also, a method of manufacturing the composition.

公开(公告)号：WO2011087701A2

公开(公告)日：2011-07-21

申请号：PCT/US2010/060630

申请日：2010-12-16

Applicant: COLGATE-PALMOLIVE COMPANY ,  PAPPAS, Iraklis ,  FITZGERALD, Michael C. ,  PAN, Long

Inventor： PAPPAS, Iraklis ,  FITZGERALD, Michael C. ,  PAN, Long

IPC: A61Q15/00

CPC classification number: A61K8/416 ,  A61K8/26 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q15/00

Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier. Also, an anhydrous antiperspirant composition.

Abstract translation: 一种制备无水止汗组合物的方法，其包含（a）提供至少一种止汗剂活性物质（包括金属盐）的混合物和至少一种其中所述至少一种止汗活性剂溶解的止汗活性剂的无水载体，所述载体 包括至少一种选自碱性酰胺和碱性胺的碱性化合物和选自阳离子和两性离子的至少一种的共晶混合物; 和（b）加热混合物以形成至少一种止汗活性物质和无水载体的稳定的共晶体系。 另外，无水止汗组合物。

公开(公告)号：WO2011057090A2

公开(公告)日：2011-05-12

申请号：PCT/US2010/055648

申请日：2010-11-05

Applicant: COLGATE-PALMOLIVE COMPANY ,  PAN, Long ,  ORTIZ, Claudio ,  PUCHALSKI, Allen

Inventor： PAN, Long ,  ORTIZ, Claudio ,  PUCHALSKI, Allen

IPC: A61K8/49

CPC classification number: A61K8/58 ,  A61K8/19 ,  A61K8/4926 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q15/00

Abstract: A method of delivering a material to a person comprising applying an anhydrous composition to a person, wherein the anhydrous composition comprises a base and metal organic framework formed from a recyclable porous material with the material adsorbed into the metal organic framework, and the recyclable porous material has a structure that breaks down when contacted with water to release the material. An anhydrous composition comprising a base and a metal organic framework formed from a recyclable porous material with the material adsorbed into the metal organic framework, wherein the recyclable porous material has a structure that breaks down when contacted with water to release the material.

Abstract translation: 一种将材料递送给人的方法，包括向人施用无水组合物，其中所述无水组合物包含由可回收的多孔材料形成的基材和金属有机骨架，其中所述材料被吸附到所述金属有机骨架中，并且所述可再循环多孔材料 具有当与水接触以释放材料时分解的结构。 一种无水组合物，其包含基底和由可回收的多孔材料形成的金属有机骨架，其中所述材料被吸附到所述金属有机骨架中，其中所述可再循环多孔材料具有当与水接触以分解材料时分解的结构。

公开(公告)号：WO2009076591A1

公开(公告)日：2009-06-18

申请号：PCT/US2008/086556

申请日：2008-12-12

Applicant: COLGATE-PALMOLIVE COMPANY ,  PAN, Long

Inventor： PAN, Long

IPC: A61K8/26 ,  A61K8/28 ,  A61Q15/00

CPC classification number: A61K8/416 ,  A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61Q15/00

Abstract: An antiperspirant active composition comprising an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3: 1, exhibiting a SEC chromatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7 and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution. The composition can optionally include zirconium. Also, methods and processes of making the same.

Abstract translation: 一种止汗活性组合物，其包含铝/氯化物摩尔比为约0.3:1至约3:1的铝盐，显示SEC峰4至峰3强度比至少为7的SEC色谱图和峰4强度更大 高于水溶液中的5峰强度。 该组合物可以任选地包括锆。 此外，制作相同的方法和过程。