公开(公告)号：BR0004819A

公开(公告)日：2001-05-22

申请号：BR0004819

申请日：2000-10-13

Applicant: DEGUSSA

Inventor： MAASSEN RALF ,  KRILL STEFFEN ,  JAEGER BARBARA ,  HUTHMACHER KLAUS

IPC: B01J27/122 ,  C07B61/00 ,  C07C46/08 ,  C07C50/02 ,  C07C50/04

Abstract: Preparation of 2,3,5-trimethyl-p-benzoquinone comprises oxidation of trimethylphenol with oxygen or an oxygen containing gas mixture in the presence of a copper halide containing catalyst and a transition metal halide, preferably iron, chromium, manganese, cobalt, nickel or zinc or a rare earth halide at 20-120 degrees C in a two-phase reaction medium. A process for the preparation of 2,3,5-trimethyl-p-benzoquinone comprises oxidation of trimethylphenol with oxygen or an oxygen containing gas mixture in the presence of a copper halide containing catalyst in a two-phase reaction medium at elevated temperature is claimed. The reaction medium comprises water and a 5-10C aliphatic alcohol or water, 1-4C aliphatic alcohol and an aromatic hydrocarbon in the presence of a catalyst comprising copper halide and a transition metal halide, preferably iron, chromium, manganese, cobalt, nickel or zinc or a rare earth halide at 20-120 degrees C.

公开(公告)号：DE19949796A1

公开(公告)日：2001-04-19

申请号：DE19949796

申请日：1999-10-15

Applicant: DEGUSSA

Inventor： SHI NONGYAN ,  HUEBNER FRANK ,  DRAPAL BERND ,  PETER RAINER ,  KRILL STEFFEN ,  HUTHMACHER KLAUS ,  WECKBECKER CHRISTOPH

IPC: B01J31/02 ,  C07B61/00 ,  C07C45/51 ,  C07C45/62 ,  C07C45/69 ,  C07C49/04 ,  C07C49/203 ,  C07C45/45 ,  C07C49/20

Abstract: A process for the preparation of unsaturated 4,5-alleneketones comprises reaction of a tertiary propargylalcohol with an alkenylalkylether or a ketal in the presence of an aliphatic sulfonic acid or salt. A process for the preparation of unsaturated 4,5-alleneketones (I) of formula (1) comprises reaction of a tertiary propargylalcohol of formula (2) with an alkenylalkylether of formula (3) or a ketal of formula (4) in the presence of an aliphatic sulfonic acid of formula (5) or sulfonic acid salt of formula (6). An Independent claim is included for a process for the preparation of unsaturated 3,5-dieneketones and their corresponding saturated ketones by isomerization or hydrogenation of 4,5-alleneketones (I) of formula (1). R -O-C(R )=CH-R (3), R SO3H (5), R SO3M (6) R , R = H, 1-20C alkyl, aryl or alkylaryl or R and R may combine to form a 5-6 membered ring; R , R = 1-4C alkyl; R ,R = 1-4C alkyl; R , R = halogen, 1-20C alkyl or cycloalkyl optionally substituted with halogen, R is additionally an optionally substituted aryl; and M = cation of an organic or inorganic base.

公开(公告)号：DE19949795A1

公开(公告)日：2001-04-19

申请号：DE19949795

申请日：1999-10-15

Applicant: DEGUSSA

Inventor： MAASSEN RALF ,  KRILL STEFFEN ,  JAEGER BARBARA ,  HUTHMACHER KLAUS

IPC: B01J27/122 ,  C07B61/00 ,  C07C46/08 ,  C07C50/02 ,  C07C50/04 ,  B01J27/128 ,  B01J27/132

Abstract: Preparation of 2,3,5-trimethyl-p-benzoquinone comprises oxidation of trimethylphenol with oxygen or an oxygen containing gas mixture in the presence of a copper halide containing catalyst and a transition metal halide, preferably iron, chromium, manganese, cobalt, nickel or zinc or a rare earth halide at 20-120 degrees C in a two-phase reaction medium. A process for the preparation of 2,3,5-trimethyl-p-benzoquinone comprises oxidation of trimethylphenol with oxygen or an oxygen containing gas mixture in the presence of a copper halide containing catalyst in a two-phase reaction medium at elevated temperature is claimed. The reaction medium comprises water and a 5-10C aliphatic alcohol or water, 1-4C aliphatic alcohol and an aromatic hydrocarbon in the presence of a catalyst comprising copper halide and a transition metal halide, preferably iron, chromium, manganese, cobalt, nickel or zinc or a rare earth halide at 20-120 degrees C.

公开(公告)号：ZA9905597B

公开(公告)日：2001-01-02

申请号：ZA9905597

申请日：1999-08-31

Applicant: DEGUSSA

Inventor： HEINZ DIETER ,  HOELDERICH WOLFGANG ,  KRILL STEFFEN ,  BOECK WOLFGANG ,  HUTHMACHER KLAUS

IPC: C07D213/79 ,  C07D213/80 ,  C07D213/803 ,  C07D213/807 ,  C07D

CPC classification number: C07D213/803 ,  C07D213/80

公开(公告)号：BR0000186A

公开(公告)日：2000-09-26

申请号：BR0000186

申请日：2000-01-27

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  WEIGEL HORST ,  HUTHMACHER KLAUS ,  SHI NONGYUAN ,  MARKOWZ GEORGE ,  HAEFNER VOLKER

IPC: B01J31/02 ,  C07B61/00 ,  C07C67/00 ,  C07C67/52 ,  C07C67/54 ,  C07C69/017 ,  C07C69/16 ,  C07C69/28 ,  C07C50/00

Abstract: In the preparation of 2,3,5-trimethyl-hydroquinone diesters (I) by catalytic acylation of keto-isophorone (II), the acylating agent is a carboxylic anhydride containing a 1-4C alkyl residue, the reaction solution is cooled to -10 to 35 (preferably 0-30) degrees C, the crystallized (I) is filtered off and the filtrate is recycled to the acylation. In the preparation of 2,3,5-trimethyl-hydroquinone diesters (I) by catalytic acylation of keto-isophorone (II), the acylating agent is a carboxylic anhydride containing a 1-4C alkyl residue, the reaction solution is cooled to -10 to 35 (preferably 0-30) degrees C (optionally after distilling off part of the obtained carboxylic acid (III)), the crystallized (I) is filtered off and the filtrate is recycled to the acylation (optionally after distilling off part of (III) and/or discarding part of the filtrate).

公开(公告)号：CA2298740A1

公开(公告)日：2000-08-11

申请号：CA2298740

申请日：2000-02-10

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  HUTHMACHER KLAUS

IPC: B01J31/26 ,  C07B61/00 ,  C07C67/00 ,  C07C67/08 ,  C07C69/017 ,  C07C69/16 ,  C07C67/14 ,  C07C69/28 ,  C07C69/78

Abstract: The invention relates to an improved process for the production of 2,3,5-trimethylhydroquinone diesters by rearrangement of 2,6,6-trimethyl-2-cyclohexene-1,4-dione (4-oxoisophorone, ketoisophorone) in the presence of a dissolved, acidic catalyst and an acylating agent, such as for example carboxylic anhydrides or carboxylic acid halides. The 2,3,5-trimethylhydroquinone diester can optionally then be saponified to give free 2,3,5-trimethyl-hydroquinone (TMHQ), which is a valuable building block in the synthesis of vitamin E.

公开(公告)号：DE19903269A1

公开(公告)日：2000-08-03

申请号：DE19903269

申请日：1999-01-28

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  WEIGEL HORST ,  HUTHMACHER KLAUS ,  SHI NONGYUAN ,  MARKOWZ GEORG ,  HAEFNER VOLKER

IPC: B01J31/02 ,  C07B61/00 ,  C07C67/00 ,  C07C67/52 ,  C07C67/54 ,  C07C69/017 ,  C07C69/16 ,  C07C69/28 ,  C07C67/48

Abstract: In the preparation of 2,3,5-trimethyl-hydroquinone diesters (I) by catalytic acylation of keto-isophorone (II), the acylating agent is a carboxylic anhydride containing a 1-4C alkyl residue, the reaction solution is cooled to -10 to 35 (preferably 0-30) degrees C, the crystallized (I) is filtered off and the filtrate is recycled to the acylation. In the preparation of 2,3,5-trimethyl-hydroquinone diesters (I) by catalytic acylation of keto-isophorone (II), the acylating agent is a carboxylic anhydride containing a 1-4C alkyl residue, the reaction solution is cooled to -10 to 35 (preferably 0-30) degrees C (optionally after distilling off part of the obtained carboxylic acid (III)), the crystallized (I) is filtered off and the filtrate is recycled to the acylation (optionally after distilling off part of (III) and/or discarding part of the filtrate).