公开(公告)号：JP2012023492A

公开(公告)日：2012-02-02

申请号：JP2010158848

申请日：2010-07-13

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO ,  YONEMITSU TETSUMASA ,  FUKUSHI GAKUHO

IPC: H04N5/225 ,  A61B1/00 ,  A61B1/04 ,  A61B19/00 ,  G03B15/00 ,  G03B15/02 ,  G03B15/14

CPC classification number: A61B5/0071 ,  A61B1/00186 ,  A61B1/00188 ,  A61B1/002 ,  A61B1/042 ,  A61B1/043 ,  A61B1/045 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0086 ,  A61B5/415 ,  A61B5/418

Abstract: PROBLEM TO BE SOLVED: To provide an imaging apparatus, an imaging system, a surgical navigation system, and an imaging method capable of imaging an image of a subject including a phosphor with a high degree of accuracy and in a short exposure time.SOLUTION: An imaging apparatus comprises: a first illumination part 22 that irradiates a subject 2 including a phosphor 1 with visible light 5; a second illumination part 23 that irradiates the subject 2 with exciting light 6; an imaging part 3 including a plurality of imaging elements that can respectively generate image signals based on injected light and an output part that respectively reads image signals from a plurality of the imaging elements and outputs image information based on each of the read image signals; a spectral element that disperses the visible light 5 to a plurality of component lights; and control means for irradiating the subject 2 while switching the visible light 5 to the exciting light 6 or vice versa, switching the image information of the visible light 5 based on each image signal of a plurality of the imaging elements to which each component light of the visible light 5 was injected to the image information of fluorescent light based on the image signals of at least one imaging element to which fluorescent light was injected or vice versa, and outputting the image information.

Abstract translation: 要解决的问题：提供一种成像装置，成像系统，手术导航系统和能够以高精度和短曝光时间对包括磷光体的对象的图像进行成像的成像方法 。 解决方案：一种成像设备包括：第一照明部分22，其将包括荧光体1的对象2照射到可见光5; 用激发光6照射被检体2的第二照明部23; 成像部分3，其包括可以分别基于注入的光产生图像信号的多个成像元件和分别从多个成像元件读取图像信号的输出部分，并且基于每个读取的图像信号输出图像信息; 将可见光5分散到多个分量光的光谱元件; 以及用于在将可见光5切换到激发光6的同时照射被摄体2的控制装置，反之亦然，根据多个成像元件的每个成像元件的每个图像信号切换可见光5的图像信息， 基于至少一个注入荧光的成像元件的图像信号将可见光5注入到荧光的图像信息中，反之亦然，并输出图像信息。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2011180442A

公开(公告)日：2011-09-15

申请号：JP2010045586

申请日：2010-03-02

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: G02B21/36 ,  G01N21/17

CPC classification number: H04N7/18 ,  G02B21/365 ,  G06K9/00127 ,  G06T7/571 ,  H04N5/2351

Abstract: PROBLEM TO BE SOLVED: To provide a device, method and program for acquisition of a sample image, capable of improving the accuracy of detection.
SOLUTION: The device includes an image sensor 15 for forming the image of a sample SPL expanded by an objective lens 12A, a movement controller for moving, in different directions at the same position of the optical axis direction, the relative position of the surface direction perpendicular to the optical axis direction between the image sensor and the image of the sample expanded by the objective lens imaged by the image sensor while moving the focus of the objective lens to the optical axis direction in the range including the sample, and a sample image acquisition unit for acquiring the sample image by exposing the image sensor during the movement by the movement controller.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供能够提高检测精度的样本图像的采集装置，方法和程序。 解决方案：该装置包括用于形成由物镜12A扩展的样本SPL的图像的图像传感器15，用于在与光轴方向相同的位置沿不同方向移动的运动控制器， 在由包括样本的范围内将物镜的焦点移动到光轴方向的同时，通过由图像传感器成像的物镜在图像传感器和样本的图像之间垂直于光轴方向的表面方向膨胀;以及 样本图像获取单元，用于通过在移动控制器的运动期间曝光图像传感器来获取样本图像。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011095685A

公开(公告)日：2011-05-12

申请号：JP2009252378

申请日：2009-11-02

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KIHARA NOBUHIRO ,  OSATO KIYOSHI ,  KISHIMA KOICHIRO

IPC: G02B21/00 ,  G02B7/02 ,  G02B7/04 ,  G02B7/28

CPC classification number: G02B21/365 ,  G02B21/006 ,  G02B21/244 ,  G02B21/34 ,  G02B27/0025

Abstract: PROBLEM TO BE SOLVED: To provide a technique for a microscope system or the like capable of automatically correcting spherical aberration.
SOLUTION: The microscope system 100 includes a housing device 10 in which a plurality of specimens 1 are housed, a microscope device 20 which acquires image data of the specimen 1, a display device 61 which displays an image of the specimen 1 (sample 2), and a controller 50 which unitary controls the respective devices. The microscope device 20 has a high-magnification image acquiring part 21 acquiring a high-magnification image of the specimen 1. The high-magnification image acquiring part 21 includes a high-magnification optical system 22 having a condenser lens 27, spherical aberration correction lenses 28 and 29, and an imaging lens 24. The spherical aberration correction lenses 28 and 29 are held to be movable along an optical axis by a lens moving mechanism 30. A main controller 51 controls the lens moving mechanism 30 to move the spherical aberration correction lenses 28 and 29 along the optical axis, so as to correct the spherical aberration. Thus, the spherical aberration is automatically corrected.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供能够自动校正球面像差的显微镜系统等的技术。 解决方案：显微镜系统100包括容纳多个样本1的容纳装置10，获取样本1的图像数据的显微镜装置20，显示样本1的图像的显示装置61（ 样本2）以及统一控制各个装置的控制器50。 显微镜装置20具有获取样本1的高倍率图像的高倍率图像获取部21.高倍率图像获取部21包括具有聚光透镜27的高倍率光学系统22，球面像差校正透镜 28和29以及成像透镜24.球面像差校正透镜28和29通过透镜移动机构30保持为可沿光轴移动。主控制器51控制透镜移动机构30移动球面像差校正 透镜28和29沿着光轴，以校正球面像差。 因此，球面像差被自动校正。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011053362A

公开(公告)日：2011-03-17

申请号：JP2009200892

申请日：2009-08-31

Applicant: Sony Corp ,  ソニー株式会社

Inventor： HAYASHI NOBUHIRO ,  KISHIMA KOICHIRO ,  YAMAMOTO TAKASHI ,  KIHARA NOBUHIRO ,  YAMAGOSHI TAKAMICHI ,  SUZUKI FUMIYASU ,  NARISAWA TATSU

IPC: G02B21/06 ,  G02B21/36

CPC classification number: G02B21/367 ,  G01N1/312 ,  G02B21/34 ,  G06K9/00134 ,  G06K9/3216 ,  G06K9/3233 ,  G06T7/11 ,  G06T7/174 ,  G06T2207/10056 ,  G06T2207/30024

Abstract: PROBLEM TO BE SOLVED: To acquire a precise magnified image while improving usability. SOLUTION: The tissue-slice image acquirement method acquires a precise dark field magnified image while improving the usability by accurately acquiring a profile shape of a tissue-section portion in a bright field thumbnail image by: correcting the profile shape of the tissue-section portion in a dark field thumbnail image based on the bright field thumbnail image; acquiring a dark field magnified image by using that profile shape; and then, displaying the bright field thumbnail image and the dark field magnified image together. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：在提高可用性的同时获取精确的放大图像。 解决方案：组织切片图像获取方法通过以下方式获得精确的暗视野放大图像，同时通过以下方式精确获取亮区缩略图图像中的组织部分的轮廓形状，同时提高可用性：校正组织的轮廓形状 基于亮场缩略图的暗场缩略图图像中的切片部分; 通过使用该轮廓形状获取暗场放大图像; 然后一起显示亮场缩略图和暗场放大图像。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011017982A

公开(公告)日：2011-01-27

申请号：JP2009163775

申请日：2009-07-10

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: G02B21/36 ,  G01N21/64 ,  G02B21/06 ,  G02B21/26 ,  H04N5/225

CPC classification number: G01N21/6458 ,  G01N15/1434 ,  G01N15/1475 ,  G01N21/6428 ,  G01N2015/1452 ,  G01N2021/1782 ,  G01N2021/8822 ,  G02B21/16 ,  G06K9/0014 ,  G06T5/003 ,  G06T5/50 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30024 ,  H04N5/76 ,  H04N5/781 ,  H04N9/8205

Abstract: PROBLEM TO BE SOLVED: To provide: a fluorescent-image acquisition apparatus for keeping a certain counting accuracy of a fluorescence marker while reducing the data capacity; a fluorescent-image acquisition method; and a fluorescent-image acquisition program.SOLUTION: A stage movement control part 42 moves a movable stage 11 in the Z-axis direction (optical axis direction of an objective lens 12A), and moves the focal point for a sample part in the thickness direction. A fluorescent-image acquisition part 43 exposes an imaging element 30 from the start of the moving of the movable stage 11 in the Z-axis direction (optical axis direction) until its completion, and acquires a fluorescent image of the sample part obtained by the exposure at the completion from the imaging element 30.

Abstract translation: 要解决的问题：提供：一种在降低数据容量的同时保持荧光标记的一定计数精度的荧光图像获取装置; 荧光图像采集方法; 和荧光图像采集程序。解决方案：舞台移动控制部分42使移动台11在Z轴方向（物镜12A的光轴方向）上移动，并将样本部分的焦点移动到厚度 方向。 荧光图像获取部43从可移动台11的移动开始到Z轴方向（光轴方向）直到完成为止，使成像元件30曝光，并且获取由 从成像元件30完成曝光。

公开(公告)号：JP2010217553A

公开(公告)日：2010-09-30

申请号：JP2009064762

申请日：2009-03-17

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: G02B21/36 ,  G02B7/28 ,  G02B21/00 ,  H04N5/225 ,  H04N5/232

CPC classification number: G02B21/34 ,  G02B21/241 ,  G02B21/244

Abstract: PROBLEM TO BE SOLVED: To generate a vivid image of a viable tissue. SOLUTION: The image generating device 1 generates a standard image P1 and another captured image PC2 by connecting a standard captured image PC1 and another captured image PC2 at a standard position Z1 and another position Z2 on respective image capturing points QC. The image generating device 1 decides whether air bubbles BB are contained in embedding material 103 based on the standard image P1, and generates the image PR of the viable tissue by replacing the standard image P1 with another image P2 on a part in which the air bubbles are contained. Thus, the image generating device 1 generates the image PR of the viable tissue nearly vivid as a whole. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：产生活组织的生动的图像。 解决方案：图像生成装置1通过将标准拍摄图像PC1和另一拍摄图像PC2连接到各个图像拍摄点QC上的标准位置Z1和另一个位置Z2来生成标准图像P1和另一拍摄图像PC2。 图像生成装置1基于标准图像P1来判定是否将气泡BB包含在嵌入材料103中，并且通过在气泡的一部分上用另一图像P2替换标准图像P1来生成活组织的图像PR 被包含。 因此，图像生成装置1整体生成几乎生动的活组织的图像PR。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2009031903A

公开(公告)日：2009-02-12

申请号：JP2007193196

申请日：2007-07-25

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: G06T1/00 ,  A61B5/117 ,  G06F21/20

CPC classification number: A61B5/1172 ,  A61B5/0062 ,  A61B5/489 ,  G06K9/0004 ,  G06K9/00906 ,  G06K2009/0006 ,  G06K2009/00932

Abstract: PROBLEM TO BE SOLVED: To provide a biometric authentication device for achieving both reduction in thickness of the device and improvement in authentication accuracy. SOLUTION: A light source driving section 171 drives a light source section 11 so that each unit light source in the light source 110 section 11 periodically illuminates by time division. An imaging device driving device 172 drives an imaging element 13 so that, while an imaging operation by a group of imaging cells (a first imaging cell group) located near each illuminating unit light source 110 is suspended, an imaging operation by a group of imaging cells (a second imaging cell group) located farther from each illuminating unit light source than the first imaging cell group is performed. Thereby, reception of reflected light on a surface of a living body 2 to be a noise component is suppressed. Further, the light source section 11 and the imaging device 13 are arranged on the same side with respect to the cover glass 12. An overall thickness of the device is reduced compared to when they are arranged to face each other with respect to the cover glass 12. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于实现设备厚度的减小和提高认证精度的生物认证设备。 解决方案：光源驱动部分171驱动光源部分11，使得光源110部分11中的每个单位光源通过时分周期地照亮。 成像装置驱动装置172驱动成像元件13，使得在位于每个照明单元光源110附近的一组成像单元（第一成像单元组）的成像操作被暂停时，通过一组成像 执行位于距离每个照明单元光源比第一成像单元组更远的单元（第二成像单元组）。 由此，能够抑制作为噪音成分的生物体2的表面的反射光的接收。 此外，光源部分11和成像装置13相对于盖玻璃12布置在同一侧。与相对于盖玻片相对布置的装置相比，该装置的整体厚度减小 12.版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008304216A

公开(公告)日：2008-12-18

申请号：JP2007149445

申请日：2007-06-05

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: G01N21/27

Abstract: PROBLEM TO BE SOLVED: To provide a biosensor rich in mass productivity, and which is capable of readily realizing a fine structure. SOLUTION: A microring resonator 32 is formed by arranging an optical waveguide 33 on a resonance-coupling position with an incidence-side optical waveguide 30a or a separation side optical waveguide 30b which does not have wavelength selectivity. A hole 34 enterable by a detection object material is provided in a part of the optical waveguide 33. When there is no material inside the hole 34, a loss of the microring resonator 32 is large, and the intensity of separation light Ld is small and a greater part turns into a linearly advancing light Lc. When a material exists inside the hole 34, the loss of the microring resonator 32 is small, and the greater part becomes the separation light Ld and the linearly advancing light Lc is reduced. Incident light L, having a prescribed wavelength including resonance light Lb, is allowed to enter the incidence-side optical waveguide 30a, and each intensity of the linearly advancing light Lc, propagating along the incident side optical waveguide 30a and/or the separation light Ld based on resonance coupling by the microring resonator 32, is detected, to thereby determine whether the detection object material exists in the hole 34 or not. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 本发明要解决的问题：提供一种生物传感器，其生产率高，能够容易地实现精细的结构。 解决方案：微波谐振器32通过在不具有波长选择性的入射侧光波导30a或分离侧光波导30b的谐振耦合位置上布置光波导33而形成。 在光波导33的一部分中设置有可由检测对象材料入射的孔34.当孔34内没有材料时，微环谐振器32的损耗大，分离光Ld的强度小， 大部分变成线性前进的光Lc。 当孔34内存在材料时，微环谐振器32的损耗小，大部分成为分离光Ld，线性前进光Lc减小。 允许具有包含共振光Lb的规定波长的入射光L进入入射侧光波导30a，并且沿着入射侧光波导30a和/或分离光Ld传播的线性前进光Lc的强度 基于微环谐振器32的谐振耦合，检测出检测对象材料是否存在于孔34中。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2007149790A

公开(公告)日：2007-06-14

申请号：JP2005339467

申请日：2005-11-24

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: H01L31/10 ,  H01L21/8242 ,  H01L27/108 ,  H01L27/14

CPC classification number: G02B6/12004 ,  G11C11/404 ,  G11C2211/4016 ,  H01L27/108 ,  H01L27/10802 ,  H01L27/144 ,  H01L29/7841 ,  H01L31/1136

Abstract: PROBLEM TO BE SOLVED: To inexpensively perform the detection of light guided through an optical waveguide on a semiconductor substrate. SOLUTION: An optical waveguide (thick portion) 61 is formed on a silicon layer 13 sandwiched by insulation films 12, 14. A light-receiving element 70 is composed of a PDSOI transistor (MOS transistor) in which a gate electrode 72 is formed on the surface of a p-type silicon layer 15 used as a channel body via a gate insulation film 71, and a source diffusion layer 73 and a drain diffusion layer 74 are formed to a depth reaching the insulation film 14. When light is guided through the optical waveguide 61, carriers are generated by a TPA (two portion absorption) phenomenon of the light, and holes remain in the channel body of the PDSOI transistor. The remaining holes are detected by the PDSOI transistor, thereby detecting light guided through the optical waveguide 61. Thus, the PDSOI transistor can be inexpensively manufactured in a usual CMOS process. COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：为了廉价地执行通过半导体衬底上的光波导引导的光的检测。 解决方案：在由绝缘膜12,14夹在的硅层13上形成光波导（厚部）61。光接收元件70由PDSOI晶体管（MOS晶体管）构成，其中栅电极72 形成在通过栅极绝缘膜71用作沟道体的p型硅层15的表面上，并且在到达绝缘膜14的深度处形成源极扩散层73和漏极扩散层74。 通过光波导61被引导，载流子由光的TPA（两部分吸收）现象产生，并且空穴保留在PDSOI晶体管的沟道体中。 剩余的孔由PDSOI晶体管检测，从而检测通过光波导61引导的光。因此，PDOS晶体管可以以通常的CMOS工艺廉价地制造。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2007141958A

公开(公告)日：2007-06-07

申请号：JP2005330530

申请日：2005-11-15

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KISHIMA KOICHIRO

IPC: H01L21/8242 ,  H01L21/762 ,  H01L27/10 ,  H01L27/108 ,  H01L29/786

CPC classification number: H01L29/7841

Abstract: PROBLEM TO BE SOLVED: To suppress the reduction of holes accumulated in a channel body during reading/writing operations of the other memory cell.
SOLUTION: A semiconductor device is composed by using a double SOI substrate having insulating films 12, 14. A silicon layer 15 is made as the channel body so as to form a gate electrode 45 on the surface of the silicon layer 15 via a gate insulating film 44. A source diffusion layer 46 and a drain diffusion layer 47 are formed at a depth reaching the insulating layer 14 so as to obtain a memory cell MC. A contact plug 48 for applying a substrate bias voltage to a silicon layer 13 is embedded as in a state of penetrating the silicon layer 15 and the insulating film 14. The substrate bias voltage is applied to the silicon layer 13 corresponding to each memory cell MC by a word line unit. A local insulating film 50 is formed extendingly in a word line direction so as to separate the silicon layer 13 corresponding to each memory cell MC by a word line unit. The substrate bias voltage is set to a value capable of preventing the reduction of the holes accumulated in the channel body during non-writing and during non-reading.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：为了抑制在另一个存储单元的读/写操作期间累积在通道体中的空穴的减少。 解决方案：通过使用具有绝缘膜12,14的双SOI衬底来组成半导体器件。制作硅层15作为沟道体，以在硅层15的表面上形成栅电极45，通过 栅极绝缘膜44.在到达绝缘层14的深度处形成源极扩散层46和漏极扩散层47，以获得存储单元MC。 在穿透硅层15和绝缘膜14的状态下嵌入用于将衬底偏置电压施加到硅层13的接触插塞48。将衬底偏置电压施加到对应于每个存储单元MC的硅层13 用字线单位。 局部绝缘膜50沿着字线方向延伸地形成，以便通过字线单元分离与每个存储单元MC相对应的硅层13。 衬底偏置电压被设置为能够防止在非写入期间和非读取期间累积在通道体中的孔的减少的值。 版权所有（C）2007，JPO＆INPIT