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    Dental and endodontic filling material and method
    1.
    发明专利
    Dental and endodontic filling material and method 有权
    牙齿和内膜填充材料及方法

    公开(公告)号：JP2013151527A

    公开(公告)日：2013-08-08

    申请号：JP2013048800

    申请日：2013-03-12

    Applicant: Ada Foundation ,  エイディーエイ ファウンデーション

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61K6/08 ,  A61K6/027 ,  A61K6/033 ,  A61K6/083

    CPC classification number: A61C5/50 ,  A61K6/0038 ,  A61K6/0067 ,  A61K6/0606 ,  A61K6/0612 ,  A61K6/0625 ,  A61K6/0643 ,  A61K6/097 ,  C08L31/04 ,  C08L1/284 ,  C08L5/04 ,  C08L29/04 ,  C08L33/08 ,  C08L5/08 ,  C08L5/06

    Abstract: PROBLEM TO BE SOLVED: To provide an endodontic filling material, and a method.SOLUTION: Provided is a dental root canal filling method including: a step of providing a hydraulic filling material; a step of inserting the hydraulic filling material into the dental root canal; and a step of congealing the material in the root canal to form a biocompatible filling material. The hydraulic filling material contains a hydrogel-forming agent and a filler. The hydrogel-forming agent is at least either one of a reactive organic hydrogel-forming agent, inorganic hydrogel-forming agent, and non-reactive organic hydrogel-forming agent. The filler is either a self-cure filler or a nonhardenable filler. The filling material can be formed from two or more precursor compositions in its original position in the dental root canal, or can be formed immediately before its insertion into the dental root canal.

    Abstract translation: 要解决的问题：提供牙髓填充材料和方法。解决方案：提供一种牙根根管填充方法，包括：提供液压填充材料的步骤; 将液压填充材料插入牙根管的步骤; 以及在根管中凝结材料以形成生物相容性填充材料的步骤。 液压填充材料含有水凝胶形成剂和填料。 水凝胶形成剂是反应性有机水凝胶形成剂，无机水凝胶形成剂和非反应性有机水凝胶形成剂中的至少一种。 填料是自固化填料或不可硬化填料。 填充材料可以由其在牙根管中的原始位置的两种或更多种前体组合物形成，或者可以在其插入牙根管之前立即形成。

    FLUORAPATITE-FORMING CALCIUM PHOSPHATE CEMENTS
    4.
    发明专利
    FLUORAPATITE-FORMING CALCIUM PHOSPHATE CEMENTS 未知

    公开(公告)号：CA2803294A1

    公开(公告)日：2012-01-05

    申请号：CA2803294

    申请日：2011-07-01

    Applicant: ADA FOUNDATION

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61L24/02 ,  A61K6/06 ,  C04B12/02

    Abstract: This study reports in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). Experimental cements contained from (0 to 3.1) mass % of F, corresponding to presence of FA at levels of approximately (0 to 87) mass %. The crystallinity of the apatitic cement product increased greatly with the FA content. When implanted subcutaneously in rats, the in vivo resorption rate decreased significantly with increasing FA content. The cement with the highest FA content was not resorbed in soft tissue, making it biocompatible and bioinert CPC. These bioinert CPCs are candidates for use in useful applications where slow or no resorption of the implant is required to achieve the desired clinical outcome.

    PREMIXED SELF-HARDENING BONE GRAFT PASTES
    5.
    发明专利
    PREMIXED SELF-HARDENING BONE GRAFT PASTES 未知

    公开(公告)号：CA2521522C

    公开(公告)日：2011-11-01

    申请号：CA2521522

    申请日：2004-03-11

    Applicant: ADA FOUNDATION

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: C04B12/02 ,  C09K3/00

    Abstract: A bone or dental implant material in the form of a paste includes a mixture of calcium phosphate and/or calcium-containing powders, liquid glycerol, organic acid and gelling agent. The paste is stable, resistant to washout and will harden upon exposure to water. Physical characteristics of the paste, including consistency, porosity, and hardening time, are controlled by the choice and ratio of constituents.

    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR
    7.
    发明专利
    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR 未知

    公开(公告)号：CA2624331A1

    公开(公告)日：2007-04-26

    申请号：CA2624331

    申请日：2006-10-19

    Applicant: ADA FOUNDATION

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61K33/42 ,  A61K31/19

    Abstract: Disclosed are dual-phase cement precursor systems and related methods and kits. The cement precursor systems are composed of a first and second discrete phases, at least one of which is aqueous. When combined, the cement precursor phases form a cement that is suitable as a bone graft material for bone repair procedures. In preferred embodiments, the materials are highly biocompatible, osteoinductive, and bioresorbable. A number of different but not mutually exclusive cement chemistries may be employed in the cement precursor systems. For instance, hydrogel-forming polymer cements, carboxyl/calcium cements, or calcium phosphate cements may be employed.

    8.
    发明专利
    未知

    公开(公告)号：AT507843T

    公开(公告)日：2011-05-15

    申请号：AT97938396

    申请日：1997-08-19

    Applicant: ADA FOUNDATION

    Inventor： CHOW LAURENCE ,  TAKAGI SHOZO ,  VOGEL GERALD

    IPC: A61K47/00 ,  A23G3/00 ,  A23G3/34 ,  A23G3/36 ,  A23G4/00 ,  A23G4/06 ,  A61K8/00 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K9/68 ,  A61K33/42 ,  A61P19/00 ,  A61Q11/00

    Abstract: The invention relates to anticarious delivery vehicles, specifically chewing gums, candies, confectioneries, toothpastes, dentifrices and gels. The invention specifically provides chewing gums, candies, confectioneries, toothpastes, dentifrices and gels containing non-toxic sparingly soluble calcium and phosphate compounds as additives, causing the release of calcium and phosphate ions into the oral cavity gradually and persistently for a period no less than 5 minutes. The invention provides released calcium phosphate ions that diffuse into partially demineralized tooth enamel or dentin, leading to remineralization and repair of caries lesions, dental plaque, open dentinal tubules and exposed dentin. The invention thus provides agents and methods for remineralization of teeth and for reducing or eradicating cariogenic challenge in plaque following sucrose intake. The formulations of the invention can thereby produce effective anticaries actions without the use of fluoride. In addition, the formulations of the invention can be used to desensitize hypersensitive teeth.

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