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    THE CELL CULTURE APPARATUS AND MASS AUTOMATIC CELL CULTURE DEVICE HAVING IT
    1.
    发明申请
    THE CELL CULTURE APPARATUS AND MASS AUTOMATIC CELL CULTURE DEVICE HAVING IT 审中-公开
    具有它的细胞培养装置和大量的自动细胞培养装置

    公开(公告)号：WO2009069962A2

    公开(公告)日：2009-06-04

    申请号：PCT/KR2008/007037

    申请日：2008-11-28

    Applicant: CORESTEM CO., LTD. ,  KIM, Kyung Suk ,  CHOUNG, Jai Jun

    Inventor： KIM, Kyung Suk ,  CHOUNG, Jai Jun

    IPC: C12M1/24

    CPC classification number: G01N35/1095 ,  C12M23/08 ,  C12M23/22 ,  C12M23/38 ,  C12M23/44 ,  C12M23/48 ,  C12M23/58 ,  C12M27/10 ,  C12M29/00 ,  C12M41/48

    Abstract: The present invention relates to a cell culture apparatus and a mass automatic cell culture device having it. There is provided a cell culture apparatus comprising a cylindrical cell culture flask which is air-tightly sealed to culture a cell using a culture solution and various gases and formed of a transparent material to observe an internal portion thereof, an injection unit for supplying the cell and the culture solution into the cell culture flask, a collection unit for discharging the cells and the culture solution from the cell culture flask, and a cell culture flask receiving part which is comprised of first and second vertical frames in which a plurality of injecting parts and collecting parts for respectively receiving the injection unit and the collection unit are vertically formed to be opposed to each other, and plate type connection parts which are respectively disposed between upper ends and lower ends of the two opposed vertical frames to be spaced apart from each other in regular intervals, thereby connecting the first and second vertical frames, and a mass automatic cell culture device having it.

    Abstract translation: 具有它的细胞培养装置和大规模自动细胞培养装置技术领域本发明涉及细胞培养装置和具有它的大规模自动细胞培养装置。 本发明提供一种细胞培养装置，其特征在于，具备：圆筒型的细胞培养用烧瓶，其被气密地密封，使用培养液和各种气体培养细胞，并由透明材料形成，观察其内部;供给单元 将培养液加入到细胞培养瓶中，从细胞培养瓶中排出细胞和培养液的收集单元，以及由第一和第二垂直框架组成的细胞培养瓶接收部分，其中多个注射部分 并且用于分别容纳注射单元和收集单元的收集部分垂直地形成为彼此相对;以及板型连接部分，分别设置在两个相对的垂直框架的上端和下端之间，以与每个 其他有规律的间隔，从而连接第一和第二垂直框架，以及大规模自动化单元 有设备。

    A CELL CULTURE FLASK AND THE CELL CULTURE DEVICE HAVING IT
    5.
    发明申请
    A CELL CULTURE FLASK AND THE CELL CULTURE DEVICE HAVING IT 审中-公开
    细胞培养片和细胞培养装置

    公开(公告)号：WO2009069960A3

    公开(公告)日：2009-10-08

    申请号：PCT/KR2008007035

    申请日：2008-11-28

    Applicant: CORESTEM CO LTD ,  KIM KYUNG SUK ,  CHOUNG JAI JUN

    Inventor： KIM KYUNG SUK ,  CHOUNG JAI JUN

    IPC: C12M1/00

    CPC classification number: C12M23/08 ,  C12M23/22 ,  C12M23/38 ,  C12M23/44 ,  C12M29/00 ,  C12M29/26

    Abstract: The present invention relates to a cell culture flask for culturing a cell using a culture solution, particularly to a cell culture flask enabling to culture a cell without any contamination, to automatically introduce and discharge the culture solution or gases and to be stacked in turn, and a cell culture device having the same. The present invention provides a cell culture flask comprising a culture space with a predetermined area for culturing the cell; one or more culture solution inlet ports for introducing the culture solution or the cell into the culture space; one or more culture solution outlet ports for discharging the culture solution or the cell supplied to the culture space; and one or more gas inlet ports for introducing the various gases into the culture space, wherein the cell culture flask is made airtight and formed of a transparent material so that a user can see an internal portion of the cell culture flask, and a cell culture device having the same.

    Abstract translation: 本发明涉及使用培养液培养细胞的细胞培养瓶，特别涉及能够培养细胞而没有任何污染的细胞培养烧瓶，以自动引入和排出培养液或气体，并依次层叠， 和具有该细胞培养装置的细胞培养装置。 本发明提供一种细胞培养瓶，其包含具有用于培养细胞的预定区域的培养空间; 用于将培养液或细胞引入培养空间的一个或多个培养溶液入口; 一个或多个培养液出口，用于排出供应到培养空间的培养液或细胞; 以及用于将各种气体引入培养空间的一个或多个气体入口，其中细胞培养瓶被气密地制成并由透明材料形成，使得使用者可以看到细胞培养瓶的内部部分和细胞培养物 具有相同的装置

    THE CELL CULTURE APPARATUS AND MASS AUTOMATIC CELL CULTURE DEVICE HAVING IT
    6.
    发明申请
    THE CELL CULTURE APPARATUS AND MASS AUTOMATIC CELL CULTURE DEVICE HAVING IT 审中-公开
    细胞培养装置和大量的自动细胞培养装置

    公开(公告)号：WO2009069962A3

    公开(公告)日：2009-08-06

    申请号：PCT/KR2008007037

    申请日：2008-11-28

    Applicant: CORESTEM CO LTD ,  KIM KYUNG SUK ,  CHOUNG JAI JUN

    Inventor： KIM KYUNG SUK ,  CHOUNG JAI JUN

    IPC: C12M1/24

    CPC classification number: G01N35/1095 ,  C12M23/08 ,  C12M23/22 ,  C12M23/38 ,  C12M23/44 ,  C12M23/48 ,  C12M23/58 ,  C12M27/10 ,  C12M29/00 ,  C12M41/48

    Abstract: The present invention relates to a cell culture apparatus and a mass automatic cell culture device having it. There is provided a cell culture apparatus comprising a cylindrical cell culture flask which is air-tightly sealed to culture a cell using a culture solution and various gases and formed of a transparent material to observe an internal portion thereof, an injection unit for supplying the cell and the culture solution into the cell culture flask, a collection unit for discharging the cells and the culture solution from the cell culture flask, and a cell culture flask receiving part which is comprised of first and second vertical frames in which a plurality of injecting parts and collecting parts for respectively receiving the injection unit and the collection unit are vertically formed to be opposed to each other, and plate type connection parts which are respectively disposed between upper ends and lower ends of the two opposed vertical frames to be spaced apart from each other in regular intervals, thereby connecting the first and second vertical frames, and a mass automatic cell culture device having it.

    Abstract translation: 细胞培养装置及具有该细胞培养装置的大容量自动细胞培养装置技术领域本发明涉及具有该细胞培养装置的大容量自动细胞培养装置。 提供一种细胞培养装置，其包括圆筒形细胞培养瓶，气瓶密封以培养细胞，使用培养液和各种气体，并由透明材料形成，以观察其内部部分，用于供应细胞的注射单元 将培养液投入到细胞培养烧瓶中，从细胞培养烧瓶中排出细胞和培养液的收集单元和由第一和第二纵向框架构成的细胞培养烧瓶容纳部，其中多个注射部 并且用于分别接收注射单元和收集单元的收集部分被竖直地形成为彼此相对，并且分别设置在两个相对的竖直框架的上端和下端之间的板型连接部分与每个 其他规则的间隔，从而连接第一和第二垂直框架和大规模自动细胞培养 具有它的设备。

    METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES COMPRISING ERYTHROPOIETIN
    7.
    发明申请
    METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES COMPRISING ERYTHROPOIETIN 审中-公开
    用于治疗包含ERYTHROPOIETIN的电动神经元疾病的方法和组合物

    公开(公告)号：WO2007136155A1

    公开(公告)日：2007-11-29

    申请号：PCT/KR2006/005065

    申请日：2006-11-28

    Applicant: CORESTEM CO., LTD. ,  CHOUNG, Jai Jun ,  KIM, Seung Hyun ,  KIM, Hee Tae ,  KOH, Seong Ho ,  KIM, Hyun Young

    Inventor： CHOUNG, Jai Jun ,  KIM, Seung Hyun ,  KIM, Hee Tae ,  KOH, Seong Ho ,  KIM, Hyun Young

    IPC: A61K38/18

    CPC classification number: A61K38/1816 ,  A61K38/00

    Abstract: The present invention relates to a composition for treating motor neuron diseases, particularly amyotrophic lateral sclerosis (ALS), comprising erythropoietin (EPO), an erythropoietin fragment, or an analogue thereof, and a method for treating motor neuron diseases using the composition. The composition and treatment method of the present invention can provide effective therapy for motor neuron diseases, particularly for amyotrophic lateral sclerosis (ALS).

    Abstract translation: 本发明涉及用于治疗运动神经元疾病的组合物，特别是包含促红细胞生成素（EPO），红细胞生成素片段或其类似物的肌萎缩性侧索硬化（ALS），以及使用该组合物治疗运动神经元疾病的方法。 本发明的组合物和治疗方法可以为运动神经元疾病，特别是肌萎缩性侧索硬化（ALS）提供有效的治疗。

    SYRINGE-SHAPED CULTURE TUBE AND CELL CULTURE APPARATUS USING SAME
    9.
    发明申请
    SYRINGE-SHAPED CULTURE TUBE AND CELL CULTURE APPARATUS USING SAME 审中-公开
    SYRINGE形文化管和使用相同的细胞培养装置

    公开(公告)号：WO2010036023A3

    公开(公告)日：2010-07-15

    申请号：PCT/KR2009005427

    申请日：2009-09-23

    Applicant: CORESTEM CO LTD ,  HONG SEOK KEE ,  YANG SI EUN ,  KIM KYUNG SUK ,  YOON HYUN SOO ,  LEE TAE YONG ,  LEE JIN HWA

    Inventor： HONG SEOK KEE ,  YANG SI EUN ,  KIM KYUNG SUK ,  YOON HYUN SOO ,  LEE TAE YONG ,  LEE JIN HWA

    IPC: C12M1/24

    CPC classification number: C12M27/10 ,  C12M23/08

    Abstract: The present invention relates to a syringe-shaped culture tube which has a wide surface area and is changeable by a user to a desirable size, and a cell culture apparatus in which plural culture tubes are mounted. The cell culture apparatus allows the culture medium to constantly and smoothly contact the entire inner circumference of the culture tube and rotate by a rotation unit at a preset speed when the culture tube is filled with the culture medium. Thus, the cell culture apparatus can promote stirring and gas supply and increase the gas exchange rate. Also, the cell culture apparatus can reduce consumption of the culture medium. The cell culture apparatus according to the present invention comprises: the culture tube with culture space therein, wherein a vent hole in which the culture medium flows in and out of the culture tube is formed at one or both ends thereof and the inner diameter gradually tapers toward the outside at the other end; a rotation support member with plural culture tubes horizontally mounted in a longitudinal direction that rotates around a rotation shaft formed at the center; and a rotation unit for rotating the rotation support member around the rotation shaft.

    Abstract translation: 本发明涉及一种注射器形的培养管，其具有宽的表面积并可由使用者改变到理想的尺寸，并且其中安装有多个培养管的细胞培养装置。 细胞培养装置在培养管充满培养基时，使培养基始终平稳地接触培养管的整个内周并通过旋转单元以预设速度旋转。 因此，细胞培养装置可以促进搅拌和气体供应并提高气体交换率。 而且，细胞培养装置可以减少培养基的消耗。 根据本发明的细胞培养装置包括：其中具有培养空间的培养管，其中培养基流入和流出培养管的通气孔形成在其一端或两端，并且内径逐渐变细 向另一端的外面; 具有多个培养管的旋转支撑构件，所述培养管沿纵向方向水平地安装，所述纵向方向围绕形成在中心处的旋转轴旋转; 以及用于围绕旋转轴旋转旋转支撑构件的旋转单元。

    CELL CULTURE APPARATUS
    10.
    发明申请
    CELL CULTURE APPARATUS 审中-公开
    细胞培养设备

    公开(公告)号：WO2010036024A2

    公开(公告)日：2010-04-01

    申请号：PCT/KR2009005428

    申请日：2009-09-23

    Applicant: CORESTEM CO LTD ,  HONG SEOK KEE ,  YANG SI EUN ,  KIM KYUNG SUK ,  YOON HYUN SOO ,  LEE TAE YONG ,  LEE JIN HWA

    Inventor： HONG SEOK KEE ,  YANG SI EUN ,  KIM KYUNG SUK ,  YOON HYUN SOO ,  LEE TAE YONG ,  LEE JIN HWA

    IPC: C12M3/00

    CPC classification number: C12M27/12 ,  C12M23/50 ,  C12M27/10 ,  C12M37/00

    Abstract: The present invention relates to a cell culture apparatus. The cell culture apparatus improves productivity of cells through an automated system for serial operations from initial culture to cultured cell extraction. The culture is performed in a glove box so a user can easily observe the cell culture apparatus. Additionally, the cell culture apparatus can reduce contamination during cell culturing. The cell culture apparatus according to the present invention comprises: a cell culture device which contains a culture medium therein and in which plural culture tubes for culturing cells are mounted; a rotation unit which rotates the cell culture device in order for the culture medium to flow along the inner wall of the culture tube; an injection device for injecting cells or culture medium into the culture tube; and an extraction device for extracting culture medium from the culture tube.

    Abstract translation: 本发明涉及细胞培养装置。 细胞培养装置通过自动系统从初始培养到培养细胞提取的连续操作提高了细胞的生产力。 培养在手套箱中进行，使得使用者可以容易地观察细胞培养装置。 另外，细胞培养装置可以减少细胞培养过程中的污染。 根据本发明的细胞培养装置包括：细胞培养装置，其中包含培养基并且其中安装有用于培养细胞的多个培养管; 旋转单元，其旋转细胞培养装置以使培养基沿着培养管的内壁流动; 注射装置，用于将细胞或培养基注射到培养管中; 以及用于从培养管中提取培养基的提取装置。

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