公开(公告)号：WO2010056558A2

公开(公告)日：2010-05-20

申请号：PCT/US2009/062934

申请日：2009-11-02

Applicant: GREATBATCH LTD. ,  SWOYER, John ,  YE, Qingshan

Inventor： SWOYER, John ,  YE, Qingshan

IPC: A61N1/05

CPC classification number: A61N1/0534 ,  A61N1/0539 ,  A61N1/0551 ,  A61N1/086 ,  H03H1/0007 ,  H03H7/1766

Abstract: Lead extensions, systems, and methods providing MRI compatible deep brain stimulation (DBS) and spinal cord stimulation (SCS) systems are described. Lead extensions are provided having band stop filters (BSFs) which resonate at a frequency expected from MRI systems to create a very high impedance which can effectively decouple the implanted lead from the lead extension proximal of the BSF and change the effective length. Changing the effective length can reduce the likelihood of undesirably heating tissue near the DBS/SCS electrodes during MRI. Some lead extensions include BSFs in a distal connector for coupling to the lead contacts. The BSFs can be included within a burr hole cap base which can also include a connector for connecting to the DBS lead. DBS and SCS leads having a sacrificial proximal portion and intermediate electrical contacts are also provided.

Abstract translation: 描述了提供与MRI兼容的深部脑刺激（DBS）和脊髓刺激（SCS）系统的主导扩展，系统和方法。 提供具有带阻滤波器（BSF）的引线延伸部，所述带阻滤波器以MRI系统预期的频率共振以产生非常高的阻抗，其可以有效地将植入的引线与BSF近端的引线延伸部分分离并改变有效长度。 改变有效长度可以减少在MRI期间在DBS / SCS电极附近不期望地加热组织的可能性。 一些引线延伸件包括位于远端连接器中的BSF，用于耦合到引线触点。 BSF可以包含在毛刺孔盖基座内，该基座还可以包括用于连接到DBS引线的连接器。 DBS和SCS导线还具有牺牲性近端部分和中间电触点。

公开(公告)号：WO2010051265A1

公开(公告)日：2010-05-06

申请号：PCT/US2009/062167

申请日：2009-10-27

Applicant: GREATBATCH LTD. ,  JOHNSON, Robert Shawn ,  KONDABATNI, Kishore Kumar ,  WILLIAMS, Christopher Michael ,  BAUER, Ryan Thomas ,  BRAINARD, Scott ,  YE, Qingshan ,  DABNEY, Warren S. ,  STEVENSON, Robert A. ,  FLEIGLE, Jeff

Inventor： JOHNSON, Robert Shawn ,  KONDABATNI, Kishore Kumar ,  WILLIAMS, Christopher Michael ,  BAUER, Ryan Thomas ,  BRAINARD, Scott ,  YE, Qingshan ,  DABNEY, Warren S. ,  STEVENSON, Robert A.

IPC: A61N1/00

CPC classification number: H01F27/027 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3754 ,  H01F27/40 ,  H01F2017/065 ,  H01G4/40 ,  H03H1/0007 ,  H03H7/0115 ,  H03H2001/0042 ,  H03H2007/013

Abstract: One or more inductors and one or more capacitors are physically disposed relative to one another in series and are electrically connected to one another in parallel to form a bandstop filter. Chip inductors and chip capacitors having spaced apart conductive terminals are physically arranged in end-to-end abutting relation to minimize electrical potential between adjacent conductive terminals. The bandstop filter may be hermetically sealed within a biocompatible container for use with an implantable lead or electrode of a medical device. The values of the inductors and the capacitors are selected such that the bandstop filter is resonant at one or more selected frequencies, such as an MRI pulsed frequency.

Abstract translation: 一个或多个电感器和一个或多个电容器彼此相互物理地布置并且彼此并联电连接以形成带阻滤波器。 具有间隔开的导电端子的片式电感器和片式电容器以端对端邻接的方式物理地布置，以使相邻的导电端子之间的电位最小化。 带阻滤波器可以气密地密封在生物相容性容器内，以与医疗装置的可植入引线或电极一起使用。 选择电感器和电容器的值，使得带阻滤波器在一个或多个选定的频率（例如MRI脉冲频率）下谐振。

公开(公告)号：WO2009117599A2

公开(公告)日：2009-09-24

申请号：PCT/US2009/037700

申请日：2009-03-19

Applicant: GREATBATCH LTD. ,  STEVENSON, Robert, A. ,  TRUEX, Buehl, E. ,  BRENDEL, Richard, L. ,  FRYSZ, Christine, A. ,  DABNEY, Warren, S. ,  HUSSEIN, Haytham ,  ADAME, Jose Luis, Lorente ,  JOHNSON, Robert, Shawn ,  BRAINARD, Scott

Inventor： STEVENSON, Robert, A. ,  TRUEX, Buehl, E. ,  BRENDEL, Richard, L. ,  FRYSZ, Christine, A. ,  DABNEY, Warren, S. ,  HUSSEIN, Haytham ,  ADAME, Jose Luis, Lorente ,  JOHNSON, Robert, Shawn ,  BRAINARD, Scott

IPC: H03H7/00

CPC classification number: A61N1/08 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/375 ,  A61N1/3754 ,  A61N2001/086 ,  H01G4/06 ,  H01G4/35 ,  H01G4/40 ,  H01R13/7195 ,  H03H1/0007 ,  H03H7/1766 ,  H03H2001/0042 ,  H03H2001/0085 ,  H05K1/181 ,  H05K5/0095 ,  H05K9/00 ,  H05K2201/10015

Abstract: A shielded three-terminal flat-through EMI/energy dissipating filter includes an active electrode plate through which a circuit current passes between a first terminal and a second terminal, a first shield plate on a first side of the active electrode plate, and a second shield plate on a second side of the active electrode plate opposite the first shield plate. The first and second shield plates are conductively coupled to a grounded third terminal. In preferred embodiments, the active electrode plate and the shield plates are at least partially disposed with a hybrid flat-through substrate that may include a flex cable section, a rigid cable section, or both.

Abstract translation: 屏蔽三端子平通EMI /能量消散滤波器包括有源电极板，电路电流通过该有源电极板在第一端子和第二端子之间通过，第一屏蔽板在有源电极板的第一侧上，第二屏蔽板 屏蔽板在与第一屏蔽板相对的有源电极板的第二侧上。 第一和第二屏蔽板导电地耦合到接地的第三端子。 在优选实施例中，有源电极板和屏蔽板至少部分地布置有可以包括柔性电缆部分，刚性电缆部分或两者的混合平整基板。

公开(公告)号：WO1996039723A1

公开(公告)日：1996-12-12

申请号：PCT/US1996006781

申请日：1996-05-14

Applicant: WILSON GREATBATCH LTD.

Inventor： WILSON GREATBATCH LTD. ,  TAKEUCHI, Esther, S. ,  WALSH, Karen, M.

IPC: H01M06/00

CPC classification number: H01M6/168 ,  H01M6/162

Abstract: An improved alkali metal/mixed metal oxide electrochemical cell capable of delivering high current pulses, rapidly recovering its open circuit voltage and having high current capacity, is described. The stated benefits are realized by dissolving a carbon oxide such as CO2 in the electrolyte.

Abstract translation: 描述了能够提供高电流脉冲，快速恢复其开路电压并具有高电流容量的改进的碱金属/混合金属氧化物电化学电池。 通过将诸如CO 2的碳氧化物溶解在电解质中来实现所述的益处。

公开(公告)号：WO1996027216A1

公开(公告)日：1996-09-06

申请号：PCT/US1996002221

申请日：1996-02-20

Applicant: WILSON GREATBATCH LTD.

Inventor： WILSON GREATBATCH LTD. ,  TAKEUCHI, Esther, S. ,  PYSZCZEK, Michael, F.

IPC: H01M04/04

CPC classification number: H01M4/0471 ,  B22F1/0059 ,  H01M4/04 ,  H01M4/0402 ,  H01M4/0435 ,  H01M4/62 ,  H01M2004/028 ,  Y10T29/49115

Abstract: A method for preparing an electrode component comprises mixing an electrode active material in a water-based environment with the aid of surfactants. A preferred embodiment of this process comprises combining a high surface area carbonaceous cathode active material (10) with a water/surfactant mixture (14) and then adding a fluoro-polymer as the binder material to the slurry. The resulting paste (16) is processed and formed into the cathode material. This process replaces the use of isopropyl alcohol with the water/surfactant mixture as the solvent. Preferred surfactants include those of the polyglycol family.

Abstract translation: 一种制备电极组件的方法包括借助于表面活性剂在水基环境中混合电极活性材料。 该方法的优选实施方案包括将高表面积碳质正极活性材料（10）与水/表面活性剂混合物（14）组合，然后将作为粘合剂材料的氟聚合物加入到浆料中。 将所得糊状物（16）加工成阴极材料。 该方法取代了异丙醇与水/表面活性剂混合物作为溶剂的用途。 优选的表面活性剂包括聚二醇家族的表面活性剂。

公开(公告)号：WO1994029910A1

公开(公告)日：1994-12-22

申请号：PCT/US1994006205

申请日：1994-06-02

Applicant: WILSON GREATBATCH LTD.

Inventor： WILSON GREATBATCH LTD. ,  TAKEUCHI, Esther, S. ,  THIEBOLT, William, C., III

IPC: H01M04/04

CPC classification number: C01G31/00 ,  C04B35/495 ,  H01B1/08 ,  H01M4/483 ,  H01M4/5825 ,  H01M6/16

Abstract: A method for preparing a cathode having as active material silver vanadium oxide formed by chemical addition, reaction or otherwise intimate contact of elemental silver and a vanadium-containing compound present in an anhydrous mixture, is described. The present invention provides alternate preparation techniques for improving chemical control in the formation of a cathode for incorporation into an electrochemical cell.

Abstract translation: 描述了通过化学添加，反应或以其他方式紧密接触元素银和存在于无水混合物中的含钒化合物作为活性材料的银氧化钒的阴极的制备方法。 本发明提供了用于改进用于结合到电化学电池中的阴极形成中的化学控制的替代制备技术。

公开(公告)号：WO2011002533A1

公开(公告)日：2011-01-06

申请号：PCT/US2010/026481

申请日：2010-03-08

Applicant: GREATBATCH LTD. ,  STEVENSON, Robert A. ,  FRYSZ, Christine A. Frysz

Inventor： STEVENSON, Robert A. ,  FRYSZ, Christine A. Frysz

IPC: G05F3/02

CPC classification number: A61N1/37276 ,  A61B5/0031 ,  A61B90/90 ,  A61B90/98 ,  A61B2562/08 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/086 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37 ,  A61N1/3718 ,  A61N1/37223 ,  A61N1/37229 ,  A61N1/3752 ,  A61N1/3758 ,  G06K19/0701 ,  G06K19/0715 ,  G06K19/07749

Abstract: A transient voltage suppressing (TVS) circuit includes an implantable RFID chip, an antenna associated with the RFID chip, and a transient voltage suppressor electrically connected in parallel to both the RFID chip and the antenna. The transient voltage suppressor may be formed of an array of diodes, such as back-to-back diodes, at least one Zener diode, or back-to-back or series opposing Zener diodes. In preferred embodiments, the antenna is formed of a biocompatible material suitable for long-term exposure to body tissue and body fluids, and the RFID chip and the transient voltage suppressor are disposed within a hermetically sealed biocompatible container.

Abstract translation: 瞬态电压抑制（TVS）电路包括可植入RFID芯片，与RFID芯片相关联的天线，以及与RFID芯片和天线并联电连接的瞬态电压抑制器。 瞬态电压抑制器可以由二极管阵列形成，诸如背对背二极管，至少一个齐纳二极管或背对背或串联对置的齐纳二极管。 在优选实施例中，天线由适于长期暴露于身体组织和体液的生物相容性材料形成，并且RFID芯片和瞬态电压抑制器设置在密封的生物相容容器内。

公开(公告)号：WO2010151366A1

公开(公告)日：2010-12-29

申请号：PCT/US2010/032385

申请日：2010-04-26

Applicant: GREATBATCH LTD. ,  STEVENSON, Robert, A. ,  DABNEY, Warren, S. ,  FRYSZ, Christine, A., Frysz ,  TRUEX, Buehl, E. ,  HALPERIN, Henry, R. ,  LARDO, Albert, C.

Inventor： STEVENSON, Robert, A. ,  DABNEY, Warren, S. ,  FRYSZ, Christine, A., Frysz ,  TRUEX, Buehl, E. ,  HALPERIN, Henry, R. ,  LARDO, Albert, C.

IPC: A61B18/04 ,  A61N1/00

CPC classification number: A61N1/3718 ,  A61B5/042 ,  A61B5/055 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2090/374 ,  A61B2562/182 ,  A61B2562/222 ,  A61B2562/227 ,  A61N1/086 ,  G01R33/287

Abstract: Decoupling circuits are provided which transfer energy induced from an MRI pulsed RF field to the housing for an active implantable medical device (AIMD) which serves as an energy dissipating surface. This is accomplished through broadband filtering or by resonant filtering. In a passive component network for an AIMD, a frequency selective energy diversion circuit is provided for diverting high-frequency energy away from an AIMD lead to the AIMD housing for dissipation of said high-frequency energy.

Abstract translation: 提供去耦电路，其将从MRI脉冲RF场引起的能量转移到用作用作能量消散表面的有源可植入医疗装置（AIMD）的壳体。 这是通过宽带滤波或谐振滤波实现的。 在用于AIMD的无源分量网络中，提供频率选择能量转向电路，用于将高频能量远离AIMD导线转移到AIMD壳体，以耗散所述高频能量。

公开(公告)号：WO2010107926A1

公开(公告)日：2010-09-23

申请号：PCT/US2010/027677

申请日：2010-03-17

Applicant: GREATBATCH LTD. ,  TRUEX, Buehl E. ,  STEVENSON, Robert A. ,  BRENDEL, Richard L.

Inventor： TRUEX, Buehl E. ,  STEVENSON, Robert A. ,  BRENDEL, Richard L.

IPC: A61N1/375

CPC classification number: A61N1/37 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3754

Abstract: An EMI shielded conduit assembly for an active implantable medical device (AIMD) includes an EMI shielded housing for the AIMD, a hermetic feedthrough terminal associated with the AIMD housing, and an electronic circuit board, substrate or network disposed within the AIMD housing remote from the hermetic feedthrough terminal. At least one leadwire extends from the hermetic feedthrough terminal to the remote circuit board, substrate or network. An EMI shield is conductively coupled to the AIMD housing and substantially co-extends about the leadwire in non-conductive relation thereto.

Abstract translation: 用于有源可植入医疗装置（AIMD）的EMI屏蔽导管组件包括用于AIMD的EMI屏蔽壳体，与AIMD壳体相关联的密封馈通端子，以及布置在AIMD壳体内的电子电路板，衬底或网络，远离 密封馈通终端。 至少一根引线从密封馈通端子延伸到远程电路板，基板或网络。 EMI屏蔽件导电地耦合到AIMD壳体并且以与导电关系非导电关系的方式基本上围绕导线共同延伸。

公开(公告)号：WO2010107608A1

公开(公告)日：2010-09-23

申请号：PCT/US2010/026548

申请日：2010-03-08

Applicant: GREATBATCH LTD. ,  STEVENSON, Robert, A. ,  FRYSZ, Christine A. Frysz

Inventor： STEVENSON, Robert, A. ,  FRYSZ, Christine A. Frysz

IPC: A61N1/02

CPC classification number: A61N1/37276 ,  A61B5/0031 ,  A61B90/90 ,  A61B90/98 ,  A61B2562/08 ,  A61N1/36082 ,  A61N1/37 ,  A61N1/3718 ,  A61N1/37223 ,  A61N1/37229 ,  A61N1/3752 ,  A61N1/3758 ,  G06K19/07749

Abstract: A telemetry wake-up circuit is electrically disposed between a telemetry transceiver associated with an AIMD, and an RF tag. The RF tag may be remotely interrogated to generate a signal to which the telemetry wake-up circuit is responsive to switch the telemetry transceiver from a sleep mode to an active telemetry mode. In the sleep mode, the telemetry transceiver draws less than 25,000 nanoamperes from the AIMD, and preferably less than 500 nanoamperes.

Abstract translation: 遥测唤醒电路电气地设置在与AIMD相关联的遥测收发器和RF标签之间。 可以远程询问RF标签以产生遥测唤醒电路响应于将遥测收发器从睡眠模式切换到活动遥测模式的信号。 在睡眠模式下，遥测收发器从AIMD中抽取少于25,000纳帕，优选小于500纳安。