Abstract:
PROBLEM TO BE SOLVED: To provide an effective method for depositing inert polymers and pharmaceutical or biological agents onto a substrate, where the collection process is efficient, the coating produced is conformal, substantially defect-free and uniform, the composition of the coating can be regulated and the morphology and/or secondary structure of the pharmaceutical or biological agents can be controlled.SOLUTION: The method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate includes steps of: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.
Abstract:
PROBLEM TO BE SOLVED: To provide a method for forming a stent comprising a bioabsorbable polymer and a pharmaceutical or biological agent in powder form onto a substrate.SOLUTION: A method for preparing a laminate coronary stent comprises steps of: providing a stent framework; and depositing a plurality of layers on the stent framework to form the laminate coronary stent, wherein the framework is electrostatically charged. Here, at least one of the layers comprises a bioabsorbable polymer.
Abstract:
PROBLEM TO BE SOLVED: To provide an efficient method which applies an inactive polymer and medical or biological agent to a substrate so that the collection process is efficient, the coating produced is superficially conformal, substantially defect-free and uniform, the composition of the coating can be regulated and the morphology and/or secondary structure of the pharmaceutical or biological agents can be controlled.SOLUTION: The coating includes a stent scaffold, rapamycin, and polymer. A coated coronary stent has crystalline rapamycin of at least 50%.
Abstract in simplified Chinese:一种可为一基材加工之压力室总成包括一压力容器,其构成一封闭压力室。该压力室内设有一基材固持器,其可固持该基材。一驱动总成可移动该基材固持器。该驱动总成包括:一第一驱动组件,其连接于该基材固持器,俾随该基材固持器、相对于该压力容器而移动;及一第二驱动组件,其与该第一驱动组件间无法以流体相通,其与该压力室间亦无法以流体相通。一驱动单元可移动该第二驱动组件。该驱动单元与该第一驱动组件间无法以流体相通,该驱动单元与该压力室间亦无法以流体相通。该第二驱动组件系以非机械方式连接于该第一驱动组件,致使该驱动单元可透过该第一及第二驱动组件移动该基材固持器。
Abstract in simplified Chinese:本发明叙述可用于自基材清除金属或将金属涂覆于基材上之组合物:(a)稠化二氧化碳连续相;(b)在该二氧化碳连续相中之极性不连续相;(c)在该不连续相中之金属(即,自基材移除或涂覆于基材上之金属);(d)至少一种在该连续相、该不连续相、或该连续与该不连续相中之配位子。
Abstract in simplified Chinese:一种可与一基材及一加工流体流搭配使用之加工室总成包括一容器及一喷洒组件。该容器构成一室。该喷洒组件包括至少一个形成于该喷洒组件中之喷口,其可在该室内将该加工流体流分布于该基材上。该加工流体可从该喷洒组件中、经由该至少一个喷口流出,而该喷洒组件亦将依此作出反应,绕一转动轴、相对于该容器而旋转。
Abstract in simplified Chinese:本发明系关于一种处理一半导体基材之介电表面部分之方法,其包括下述步骤:(α)提供一具一介电表面部分之半导体基材;及然后(b)使用一涂布试剂处理该介电表面部分,该涂布试剂包括一连接至一配位基团的反应性基团,该配位基团结合有一金属,因此该金属可沉积于该介电表面部分上以产生一经一金属处理之表面部分。
Abstract in simplified Chinese:一种用于在液态或超临界二氧化碳处理介质中处理微电子基板之系统,其包含:(a)复数个二氧化碳处理室;(b)与该等二氧化碳处理室之每一个有效相连的二氧化碳供给容器;(c)与该等二氧化碳处理室中至少一个有效相连之第一处理化学制剂供给容器;(d)与该等二氧化碳处理室中至少一个有效相连之废料收集容器;及(e)与该等复数个处理室、该二氧化碳供给容器、该真空泵(若存在)、该第一处理化学制剂供给容器及该废料收集容器有效相连之控制器,该控制器被组态以在该等处理室的每一个中独立处理微电子基板。
Abstract in simplified Chinese:一种于二氧化碳溶剂系统中进行正调微影术之方法,其包括以下步骤:(a)提供一基材,该基材上形成有一聚合物抗蚀剂层;(b)使该聚合物抗蚀剂层之至少一部分暴露于辐射能下,以在聚合物抗蚀剂层中形成至少一光场区域;然后(c)在优先移除该至少一部分光场区域的条件下,使该聚合物抗蚀剂层与二氧化碳溶剂系统接触,该溶剂系统以包含一极性基团为佳。
Abstract in simplified Chinese:一种可与一基材搭配使用之加工室总成包括一容器及一基材固持器。该容器构成一室。该基材固持器具有一转动轴,且包括位置相对之前、后表面。该前表面可支撑该基材。至少一片动轮叶系由该后表面向后伸出,并沿该转动轴之径向延伸。若令该基材固持器绕该转动轴旋转,该动轮叶可产生一压差,其有助于将该基材固定于该基材固持器上。该加工室总成最好包括复数片动轮叶,且该等动轮叶系由该后表面向后伸出,并沿该转动轴之径向延伸。