公开(公告)号：BR112020018639A2

公开(公告)日：2020-12-29

申请号：BR112020018639

申请日：2019-03-14

Applicant: MEDICAGO INC ,  MITSUBISHI TANABE PHARMA CORP ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： KO KATO ,  MARC-ANDRE D'AOUST ,  PIERRE-OLIVIER LAVOIE ,  SHOTARO YAMASAKI

IPC: A01H5/00 ,  C07K14/11 ,  C12N5/10 ,  C12N15/113 ,  C12N15/13 ,  C12N15/33 ,  C12N15/40 ,  C12N15/44 ,  C12N15/82 ,  C12P21/02

Abstract: é fornecido um potenciador de expressão isolado ativo em uma planta, porção de uma planta ou célula vegetal. o potenciador de expressão isolado pode ser selecionado do grupo que consiste em nbmt78 (seq id no: 1); nbatl75 (seq id nº: 2); nbdj46 (seq id nº: 3); nbchp79 (seq id no: 4); nben42 (seq id nº: 5); athsp69 (seq id no: 6); atgrp62 (seq id no: 7); atpk65 (seq id nº: 8); atrp46 (seq id no: 9); nb30s72 (seq id nº: 10); nbgt61 (seq id nº: 11); nbpv55 (seq id nº: 12); nbppi43 (seq id nº: 13); nbpm64 (seq id nº: 14); e nbh2a86 (seq id no: 15). métodos para uilização do potenciador de expressão isolado também são fornecidos.

公开(公告)号：CA3097006A1

公开(公告)日：2019-10-17

申请号：CA3097006

申请日：2019-04-09

Applicant: NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： KATO KO

IPC: C12N15/113 ,  A01H1/00 ,  A01H5/00 ,  C12N5/10 ,  C12N15/82 ,  C12P21/02

Abstract: The purpose of the present invention is to provide technology for identifying a 5' UTR having excellent translation ability while taking into account 5' UTR variants in monocotyledons, providing a DNA molecule that codes for the 5' UTR, and efficiently producing a recombinant protein in the monocotyledons. It is possible to efficiently produce a recombinant protein in a monocotyledon by using a nucleic acid structure in a polynucleotide that codes for a foreign protein, said structure comprising a base sequence among the base sequences shown in sequences 1-4 and linking to a 5' UTR or a variant thereof.

公开(公告)号：AU2012287963B2

公开(公告)日：2016-09-22

申请号：AU2012287963

申请日：2012-07-24

Applicant: NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  THE REPUBLIC OF BOTSWANA

Inventor： KAJIKAWA MASATAKA ,  YOKOTA AKIHO ,  AKASHI KINYA ,  MAPHANYANE SEJA GASENONE ,  MOSUPI PHAROAH ,  CHITE STEPHEN MAJARA ,  KATO NORIO

IPC: C12N15/09 ,  A01H1/00 ,  A01H5/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10

Abstract: Elongation of roots of plants can be accelerated and biomass can be increased, by increasing the expression in plants of a gene, etc., that codes a protein comprising an amino acid sequence described in sequence number 1.

公开(公告)号：ZA202006210B

公开(公告)日：2024-12-18

申请号：ZA202006210

申请日：2020-10-07

Applicant: MEDICAGO INC ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  MITSUBISHI TANABE PHARMA CORP

Inventor： LAVOIE PIERRE-OLIVIER ,  D'AOUST MARC-ANDRE ,  KATO KO ,  YAMASAKI SHOTARO

Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbMT78 (SEQ ID NO: 1); nbATL75 (SEQ ID NO:2); nbDJ46 (SEQ ID NO:3); nbCHP79 (SEQ ID NO:4); nbEN42 (SEQ ID NO:5); atHSP69 (SEQ ID NO:6); atGRP62 (SEQ ID NO:7); atPK65 (SEQ ID NO:8); atRP46 (SEQ ID NO:9); nb30S72 (SEQ ID NO: 10); nbGT61 (SEQ ID NO: 11); nbPV55 (SEQ ID NO: 12); nbPPI43 (SEQ ID NO: 13); nbPM64 (SEQ ID NO: 14); and nbH2A86 (SEQ ID NO: 15). Methods for using the isolated expression enhancer are also provided.

公开(公告)号：AU2019233860A1

公开(公告)日：2020-10-15

申请号：AU2019233860

申请日：2019-03-14

Applicant: MEDICAGO INC ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  MITSUBISHI TANABE PHARMA CORP

Inventor： LAVOIE PIERRE-OLIVIER ,  D'AOUST MARC-ANDRE ,  KATO KO ,  YAMASAKI SHOTARO

IPC: C12N15/113 ,  A01H5/00 ,  C07K14/11 ,  C12N5/10 ,  C12N15/13 ,  C12N15/33 ,  C12N15/40 ,  C12N15/44 ,  C12N15/82 ,  C12P21/02

Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbMT78 (SEQ ID NO: 1); nbATL75 (SEQ ID NO:2); nbDJ46 (SEQ ID NO:3); nbCHP79 (SEQ ID NO:4); nbEN42 (SEQ ID NO:5); atHSP69 (SEQ ID NO:6); atGRP62 (SEQ ID NO:7); atPK65 (SEQ ID NO:8); atRP46 (SEQ ID NO:9); nb30S72 (SEQ ID NO: 10); nbGT61 (SEQ ID NO: 11); nbPV55 (SEQ ID NO: 12); nbPPI43 (SEQ ID NO: 13); nbPM64 (SEQ ID NO: 14); and nbH2A86 (SEQ ID NO: 15). Methods for using the isolated expression enhancer are also provided.

公开(公告)号：CA3093592A1

公开(公告)日：2019-09-19

申请号：CA3093592

申请日：2019-03-14

Applicant: MEDICAGO INC ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  MITSUBISHI TANABE PHARMA CORP

Inventor： LAVOIE PIERRE-OLIVIER ,  D'AOUST MARC-ANDRE ,  KATO KO ,  YAMASAKI SHOTARO

IPC: C12N15/113 ,  A01H5/00 ,  C07K14/11 ,  C12N5/10 ,  C12N15/13 ,  C12N15/33 ,  C12N15/40 ,  C12N15/44 ,  C12N15/82 ,  C12P21/02

Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbMT78 (SEQ ID NO: 1); nbATL75 (SEQ ID NO:2); nbDJ46 (SEQ ID NO:3); nbCHP79 (SEQ ID NO:4); nbEN42 (SEQ ID NO:5); atHSP69 (SEQ ID NO:6); atGRP62 (SEQ ID NO:7); atPK65 (SEQ ID NO:8); atRP46 (SEQ ID NO:9); nb30S72 (SEQ ID NO: 10); nbGT61 (SEQ ID NO: 11); nbPV55 (SEQ ID NO: 12); nbPPI43 (SEQ ID NO: 13); nbPM64 (SEQ ID NO: 14); and nbH2A86 (SEQ ID NO: 15). Methods for using the isolated expression enhancer are also provided.

公开(公告)号：AU2007221680B2

公开(公告)日：2012-07-05

申请号：AU2007221680

申请日：2007-03-02

Applicant: NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： YOKOTA AKIHO ,  YOSHIMURA KAZUYA ,  AKASHI KINYA

IPC: C12N15/09 ,  A01H5/00

Abstract: Mainly disclosed are: a plant whose root elongation is enhanced by utilizing a genetically engineering technique; a plant whose root elongation capability is not suppressed even under high osmotic pressure stress; a method for enhancing the elongation of a root in a plant; and others. A transgenic plant in which a Ran protein derived from a wild-type water-melon ( ) is expressed is prepared by utilizing a genetically engineering technique.

公开(公告)号：ZA202107581B

公开(公告)日：2024-12-18

申请号：ZA202107581

申请日：2021-10-08

Applicant: MITSUBISHI TANABE PHARMA CORP ,  MEDICAGO INC ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： LAVOIE PIERRE-OLIVIER ,  D'AOUST MARC-ANDRE ,  KATO KO ,  YAMASAKI SHOTARO

Abstract: An isolated expression enhancer active in a plant, portion of a plant or plant cell, the expression enhancer is provided. The isolated expression enhancer may be selected from the group consisting of nbEPI42 (SEQ ID NO:1); nbSNS46 (SEQ ID NO:2); nbCSY65 (SEQ ID NO:3); nbHEL40 (SEQ ID NO:4); and nbSEP44 (SEQ ID NO:5). Methods for using the isolated expression enhancer are also provided.

公开(公告)号：ES2691985T3

公开(公告)日：2018-11-29

申请号：ES14152631

申请日：2009-04-28

Applicant: IDEMITSU KOSAN CO ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： SAWADA KAZUTOSHI ,  YOSHIDA KAZUYA ,  MATSUI TAKESHI

IPC: C12N15/09 ,  A01H5/00 ,  A61K39/00 ,  A61K39/106 ,  A61K39/108 ,  A61K39/112 ,  A61P31/04 ,  C07K14/245 ,  C07K14/25 ,  C07K14/28 ,  C07K19/00 ,  C12N5/10 ,  C12N15/82

Abstract: Una proteína híbrida que comprende dos proteínas toxinas seleccionadas del grupo que consiste en proteína toxina Shiga (Stx), proteína toxina del cólera (CT) y proteína toxina lábil al calor de Escherichia coli (LT), en donde dichas proteínas toxinas se unen en tándem a través de un péptido que tiene las siguientes características (A), (B), (C), (D), (E), y (F), y el péptido se añade al extremo carboxi de la proteína híbrida: (A) un número de aminoácidos es de 12 a 30, más preferiblemente de 12 a 22; (B) un contenido en prolina es del 20 al 35%, más preferiblemente del 20 al 27%; y (C) la prolina se distribuye cada dos o tres aminoácidos; (D) el contenido total de alanina, metionina y ácido glutámico en los aminoácidos diferentes de prolina es el 10% o menor; (E) el contenido total de triptófano, leucina, isoleucina, tirosina, fenilalanina y valina en los aminoácidos diferentes de prolina es el 5% o menor; y (F) el contenido total de serina, glicina y asparragina en los aminoácidos diferentes de prolina es el 90% o más.

公开(公告)号：DK2287300T3

公开(公告)日：2018-09-17

申请号：DK09738819

申请日：2009-04-28

Applicant: IDEMITSU KOSAN CO ,  NATIONAL UNIV CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： YOSHIDA KAZUYA ,  SAWADA KAZUTOSHI ,  MATSUI TAKESHI

IPC: A01H5/00 ,  A61K39/106 ,  A61K39/108 ,  A61K39/112 ,  A61P31/04 ,  C07K14/245 ,  C07K14/25 ,  C07K14/28 ,  C07K19/00 ,  C12N5/10 ,  C12N15/09