培養装置を備えるマイクロプレートリーダー
    1.
    发明专利
    培養装置を備えるマイクロプレートリーダー 有权
    与培养装置酶标仪

    公开(公告)号:JP2016516206A

    公开(公告)日:2016-06-02

    申请号:JP2016505863

    申请日:2014-10-30

    Abstract: マイクロプレートリーダー(23)は、測定空間(43)と;アクション源(45’)と;マイクロプレート(3)のウェル(2)における生物学的構造内又は生物学的構造上もたらされる又は生じさせられる信号のための測定装置(46)と;測定装置(46)の光軸(51)に関してマイクロプレート(3)のウェル(2)を位置決めする搬送支持部材(22)と、アクション源(45’)、測定装置(46)及び搬送支持部材(22)の制御装置(50)とを備えている。マイクロプレートリーダー(23)は、マイクロプレート(3)のウェル(2)からの液体の蒸発を低減するために、ウェル底を有するウェル(2)を備えるマイクロプレート(3)を収容するためのフレーム(4)を備える培養装置を備えている。フレーム(4)は、内壁(6)によって囲まれる第1開口部(5)を備えており、その寸法はマイクロプレート(3)の挿入で設計されており、内壁(6)にほぼ平行に延び、中間底(10)を介して内壁(6)に接続される外壁(9)を備えており、第1開口部(5)を囲むチャネル(11)は、マイクロプレートウェル(2)の内容物に適合される液体を収容するために、2つの壁(6、9)及び中間底(10)で形成されている。培養装置は、第2開口部(8)を備える支持面(7)を備えており、支持面(7)は、挿入されたマイクロプレート(3)を支持するように配置され、第2開口部(8)の結果、培養装置に挿入されたマイクロプレート(3)のウェル(2)の底の少なくとも一部は、第2開口部(8)によって自由にアクセス可能となっている。

    Abstract translation: 酶标仪(23),测量空间(43)和;或导致所得生物结构内或生物结构在微板的井(3)(2);操作源(45“)和 测量装置对于那些(46)信号和;和输送所述支承构件用于定位所述孔(2)的微板(3)(22)相对于所述测量装置(46)(51),动作源的光轴(45' ),控制装置和所述测量装置(46)和输送所述支承构件(22的(50))。 酶标仪(23),以减少液体的蒸发从井(2)的微板(3),一个框架,用于容纳微板(3)包括一个孔(2),其具有良好基 和一个培养装置,其包括(4)。 框架(4)它设置有由所述内壁(6)包围的第一开口(5),其尺寸被设计成具有一个微板(3)的插入,基本上平行于所述内壁(6) 经由中间底部(10),围绕所述第一开口,所述通道包括外壁(9)连接到所述内壁(6)(5)(11),将微板孔的内容物(2) 以容纳液体被适配,则两个壁(6,9)和中间底部(10)形成。 培养装置具备包含第二开口的支撑表面(8)(7),所述支撑表面(7)被布置成支撑所述插入微板(3),所述第二开口 (8)作为其结果,至少在孔的底部的一部分(2)插入到所述培养装置的微板(3),其自由地成为通过第二开口接近的(8)。

    Microcuvette assembly and utilization method of same
    2.
    发明专利
    Microcuvette assembly and utilization method of same 有权
    MICROCUVETTE组装及其利用方法

    公开(公告)号:JP2009085958A

    公开(公告)日:2009-04-23

    申请号:JP2008256393

    申请日:2008-10-01

    Abstract: PROBLEM TO BE SOLVED: To provide a microcuvette assembly for properly holding a liquid sample.
    SOLUTION: A microcuvette 7 is formed so as to include a first partial plate 2, having a first cuvette surface 3, and a second partial plate 4 facing the first partial plate and having a second cuvette surface 5. The second cuvette surface 5 is disposed at the operation position of the microcuvette assembly 1 and is separated at a distance 6 so as to be registered and parallel to the first cuvette surface 3. A liquid volume 8 added to one of the cuvette surfaces 3, 5 is held in between two cuvette surfaces 3, 5. In the microcuvette assembly 1, the second cuvette surface 3 of the first partial plate 2 is formed as a free electron beam optical element. The microcuvette assembly 1 is formed independently a surface of a transparent body 10, disposed in an opening 9 that penetrates the first partial plate 2.
    COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题:提供用于适当地保持液体样品的微型电池组件。 解决方案:微孔玻璃7形成为包括具有第一比色皿表面3的第一部分板2和面向第一部分板的第二部分板4并具有第二反应杯表面5.第二反应杯表面 5设置在微型电池组件1的操作位置处,并且以距离6分开,以便与第一反应杯表面3对准并平行。添加到其中一个比色杯表面3,5的液体体积8保持在 在微型电池组件1中,第一部分板2的第二反应杯表面3形成为自由电子束光学元件。 微阵列组件1独立地形成在透明体10的表面上,该表面设置在穿透第一部分平板2的开口9中。(C)2009年,JPO和INPIT

    Laser scanner device
    3.
    发明专利
    Laser scanner device 有权
    激光扫描仪器

    公开(公告)号:JP2009058504A

    公开(公告)日:2009-03-19

    申请号:JP2008207695

    申请日:2008-08-12

    Abstract: PROBLEM TO BE SOLVED: To provide an alternative laser scanner device arranged on a slide to form an image of a fluorescent sample treated using fluorescent pigments. SOLUTION: This laser scanner device 1 is provided with a motorized transport device 3 for moving a slide from a storage unit 4 to a sample table 2 and back. The storage unit 4 includes a sample part 7 for a sample slide 8 and a test part 9 for test slides 10, each part having a depository 6 and being accessible to the transport device 3 during the operation of the laser scanner device 1. The test part 9 is implemented separately from the sample part 7 and is permanently connected to the laser scanner device 1 as a test part magazine 9' for the test slide 10. The test slide 10 stored in the test part 9 is not manually accessible for an operator in the operating state of the laser scanner device 1. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题:提供布置在载玻片上的替代激光扫描仪装置,以形成使用荧光颜料处理的荧光样品的图像。 解决方案:该激光扫描仪装置1设置有用于将载玻片从存储单元4移动到样品台2并返回的电动输送装置3。 存储单元4包括用于样本滑块8的样本部分7和用于测试滑块10的测试部分9,每个部分具有托架6,并且在激光扫描仪装置1的操作期间可被运输装置3访问。测试 部分9与样品部分7分开实施,并且与激光扫描仪装置1永久连接,作为用于测试滑片10的测试零件盒9'。存储在测试部件9中的测试滑块10不能为操作者手动访问 在激光扫描仪装置1的操作状态下。(C)2009,JPO&INPIT

    Storage unit for storing and arranging biological samples and transport system
    4.
    发明专利
    Storage unit for storing and arranging biological samples and transport system 有权
    储存和安置生物样本和运输系统的储存单位

    公开(公告)号:JP2007228971A

    公开(公告)日:2007-09-13

    申请号:JP2007052390

    申请日:2007-03-02

    Abstract: PROBLEM TO BE SOLVED: To provide a storage unit for storing and arranging many biological samples. SOLUTION: This storage unit (1) has horizontal main footprints (2) and many storage compartments (3) which are separated through middle walls (4) from each other and are surrounded with peripheral frames (5). The middle walls (4) and the peripheral frames (5) are vertically arranged on the main footprints (2). The storage compartments (3) each has both the first opening (6) and the second opening (7). The storage compartments (3) each is formed in the shape of a biopsy cassette (8) or in the shape of a glass slide (30), and has a holding means (9). The biopsy cassette (8) or the glass slide (30) which is inserted into the storage compartment (3) through the first opening (6) or the second opening (7) and perpendicularly stands is prevented from dropping through the first opening (6) or the second opening (7) with the holding means (9). COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题:提供用于存储和布置许多生物样品的存储单元。 解决方案:该存储单元(1)具有水平的主足迹(2)和许多通过中间壁(4)彼此分离并且被周边框架(5)包围的存储隔间(3)。 中间壁(4)和周边框架(5)垂直设置在主脚印(2)上。 存储室(3)各自具有第一开口(6)和第二开口(7)。 储存室(3)各自形成为活检盒(8)的形状或者是玻璃滑板(30)的形状,并具有保持装置(9)。 穿过第一开口(6)或第二开口(7)并垂直放置的插入存储隔间(3)的活检盒(8)或玻璃滑板(30)不会通过第一开口 )或具有保持装置(9)的第二开口(7)。 版权所有(C)2007,JPO&INPIT

    Device, system, and method for aspirating liquid from spe plate

    公开(公告)号:JP2004163396A

    公开(公告)日:2004-06-10

    申请号:JP2003154770

    申请日:2003-05-30

    Abstract: PROBLEM TO BE SOLVED: To provide a device for aspirating a liquid from an SPE plate for solid phase extraction and elution of organic and/or inorganic particles, which is free from conventional disadvantages. SOLUTION: In this device 1 for aspirating the liquid from the wells 3 and/or extraction chambers 4 of the SPE plate 5 for solid phase extraction and elution of organic/inorganic particles, each extraction chamber is arranged on the bottom side of each well and has an outlet 8 including an annular wall 7. This device comprises a suction chamber 11 delimited by an enclosure member 10, a receiving opening part 12 arranged in a part of the enclosure member and having an end region, which may be sealed to the surrounding atmosphere by applying a part of the SPE plate, a partial vacuum line 15 connected to a suction pump to evacuate the suction chamber, and a suction member 18 having a plurality of sucking opening parts 19. The number and distribution of the suction opening parts correspond to the number and distribution of the wells and/or extraction chambers of the SPE plate arranged on the end region 13, and an intermediate space 21 is defined by the suction member, the bottom part of the SPE plate, and the enclosure member. The enclosure member includes an air valve for guiding a flushing gas to the intermediate space. COPYRIGHT: (C)2004,JPO

    Laser scanner apparatus for fluorescence measurements
    6.
    发明专利
    Laser scanner apparatus for fluorescence measurements 有权
    激光扫描仪用于荧光测量

    公开(公告)号:JP2009104136A

    公开(公告)日:2009-05-14

    申请号:JP2008271733

    申请日:2008-10-22

    CPC classification number: G02B21/0076 G02B5/04 G02B26/105 G02B27/141

    Abstract: PROBLEM TO BE SOLVED: To provide a laser scanner apparatus for imaging and/or measuring fluorescent samples which are treated with two different fluorescent dyes. SOLUTION: The laser scanner apparatus (1) includes: lasers (51, 52) and a first optical system (53) for providing two laser beams (54, 55) of differing wavelength; an optical deflection element (56); a first objective (57); a second optical system (58); and two detectors (61, 61') for detecting emission beam bundles (59, 60). The optical deflection element (56) includes a wedge-shaped dichroic mirror (62) with front and rear dichroic surfaces (63, 64) which are arranged at an intermediate angle (β). The mirror (62) is adjusted in such a way that the two laser beams (54, 55) are each reflected at one of the surfaces (63, 64) and causes a spatial separation of the two resulting focal points (65) and the two emission beam bundles (59, 60). COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题:提供一种用于成像和/或测量用两种不同荧光染料处理的荧光样品的激光扫描仪装置。 激光扫描仪装置(1)包括:激光器(51,52)和用于提供不同波长的两个激光束(54,55)的第一光学系统(53) 光学偏转元件(56); 第一个目标(57); 第二光学系统(58); 和用于检测发射束束(59,60)的两个检测器(61,61')。 光学偏转元件(56)包括具有以中间角度(β)布置的前后分色表面(63,64)的楔形分色镜(62)。 镜子(62)以这样一种方式调节,使得两个激光束(54,55)各自在一个表面(63,64)处被反射并且导致两个产生的焦点(65)和 两个发射束束(59,60)。 版权所有(C)2009,JPO&INPIT

    Small storage system and its use
    7.
    发明专利
    Small storage system and its use 审中-公开
    小储存系统及其使用

    公开(公告)号:JP2008169042A

    公开(公告)日:2008-07-24

    申请号:JP2007316936

    申请日:2007-12-07

    CPC classification number: F25D25/04 B65G1/127

    Abstract: PROBLEM TO BE SOLVED: To provide a compact storage system and a corresponding method for storing frozen specimens.
    SOLUTION: The compact storage system comprises a storage area, a housing with a thermal insulation part, and at least one refrigeration unit that can cool at least the storage area to a temperature of at least -15°C. The compact storage system also comprises storage shelves arranged completely within the refrigerated storage area and a transfer area arranged above the storage area. An essentially horizontally moving robot is arranged within the transfer area. The compact storage system further comprises at least one essentially vertical paternoster device and the paternoster device includes a plurality of storage shelves that circulate on an essentially oval path and are essentially horizontally oriented.
    COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题:提供紧凑的存储系统和用于存储冷冻样品的相应方法。 解决方案:紧凑型存储系统包括存储区域,具有绝热部件的壳体和至少一个能够至少将存储区域冷却至至少-15℃的制冷单元。 紧凑型存储系统还包括完全设置在冷藏存储区域内的储存架和设置在存储区域上方的传送区域。 在传送区域内布置了一个基本上水平移动的机器人。 紧凑型存储系统还包括至少一个基本上垂直的柱塞式装置,并且推杆装置包括在基本上椭圆形路径上循环且基本上水平定向的多个储存架。 版权所有(C)2008,JPO&INPIT

    Method for measuring chemical group bound to biological molecule
    9.
    发明专利
    Method for measuring chemical group bound to biological molecule 审中-公开
    用于测量生物分子化学组的方法

    公开(公告)号:JP2005095144A

    公开(公告)日:2005-04-14

    申请号:JP2004102903

    申请日:2004-03-31

    Inventor: DOERING KLAUS

    CPC classification number: G01N33/582 C12Q1/42 C12Q1/485 Y10S436/80

    Abstract: PROBLEM TO BE SOLVED: To provide a method for simply detecting a chemical reaction in a biological molecule such as phosphorylation or dephosphorylation of a peptide.
    SOLUTION: This method for measuring the presence or absence of a chemical group bonded with the biological molecule in a sample, especially phosphoric acid group is provided. Here, such the molecules are attached with a phosphor marker as a tag and such phosphor marker is activated by irradiating the sample with light. The method is characterized by following processes; (a) a process of using the phosphor marker, in which the fluorescent light continuation period shows different values according to the presence or absence of the phosphoric acid bonded with the biological molecule; (b) a measuring process of the fluorescent light continuation time of the phosphor marker selected according to the process (a); and (c) a classifying process depending on the presence or absence of the phosphoric acid group with the biological molecules.
    COPYRIGHT: (C)2005,JPO&NCIPI

    Abstract translation: 要解决的问题:提供简单地检测生物分子中的化学反应如肽的磷酸化或去磷酸化的方法。 解决方案:提供了用于测量在样品中,特别是磷酸基团中与生物分子结合的化学基团的存在或不存在的方法。 这里,这样的分子附着有荧光标记物作为标签,并且通过用光照射样品来激活这种荧光标记物。 该方法的特征在于以下过程; (a)使用荧光标记物的方法,其中荧光灯持续期根据与生物分子结合的磷酸的存在或不存在而显示不同的值; (b)根据方法(a)选择的荧光标记物的荧光持续时间的测量过程; 和(c)根据磷酸基团与生物分子的存在或不存在的分类方法。 版权所有(C)2005,JPO&NCIPI

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