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公开(公告)号：KR101521491B1
公开(公告)日：2015-05-21
申请号：KR1020120084110
申请日：2012-07-31
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: 본발명은커피(원두또는부산물) 발효물및 이의추출물을함유하는화장료조성물에관한것으로서, 보다구체적으로는가공되지않은커피원두자체또는대부분이소비되지않고폐기되는커피부산물을유산균주를이용하여발효한후 얻어진발효액과이의발효액을제외한나머지건체커피발효잔여물을에탄올추출하여얻어진커피발효잔여추출물을유효성분으로포함하는고기능성화장료조성물에관한것이다. 본발명의커피(원두또는부산물) 발효물및 이의추출물은천연물유래의소재로서피부에안정하면서도피부세포증식효과, 항산화효과, 보습효과, 주름개선효과, 피부미백효과및 항염효과를동시에나타낼수 있으므로, 이를유효성분으로포함하는본 발명의조성물은고기능성화장료조성물로서유용하게사용될수 있다. 또한본 발명의상기커피(원두또는부산물) 발효물및 이의추출물은단가가저렴한원두자체또는폐기되어버려지는커피부산물을활용하여간단한공정을통해제조될있으므로, 시간, 노력및 비용을절감할수 있는경제적인효과를가질뿐만아니라폐기물의재활용을통한친환경적인효과도기대할수 있다.
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公开(公告)号：KR1020140140932A
公开(公告)日：2014-12-10
申请号：KR1020130061978
申请日：2013-05-30
Applicant: 서원대학교산학협력단 , 강원대학교산학협력단 , 주식회사 두산에코비즈넷
Abstract: 본 발명은 비타민 B1 유도체인 티아민 라우릴 황산염(Thiamine Di-lauryl Sulfate, TDS)을 분말 상태에서 나노 입자 형태로 수용액화 하여 방제 활성이 증진되도록 한 비타민 B1 유도체 나노 입자 수용액 및 그 제조방법에 관한 것이다. 본 발명은 종래 비타민 B1 유도체를 수용액 상태로 사용할 경우 안정성이 낮은 문제를 개선할 수 있는 비타민 B1 유도체 나노입자 수용액 제조방법을 제공하여, 비타민 B1 유도체가 항진균제 및 농약제제로 활용됨에 있어서 그 사용량을 최소화하여도 방제 효과를 증진시킬 수 있어 우수한 생물 농약으로 활용이 가능할 것이다.
Abstract translation: 本发明涉及一种维生素B1衍生物纳米粒子溶液及其制造方法，该维生素B1衍生物纳米粒子溶液通过将维生素B1衍生物的二十二烷基硫酸二烷基酯（TDS）粉末制成纳米粒子进行溶解而提高害虫防治能力。 本发明提供一种维生素B1衍生物纳米粒子溶液的制造方法，其可以解决常规维生素B1衍生物在溶液状态下的稳定性低的问题。 从而即使最小化作为抗真菌药物和农药的维生素B1衍生物的使用量也能提高害虫防治能力。 因此，维生素B1衍生物可用作优良的生物农药。
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公开(公告)号：KR1020140117096A
公开(公告)日：2014-10-07
申请号：KR1020130032052
申请日：2013-03-26
Applicant: 주식회사 서울화장품 , 주식회사 세바바이오텍 , 서원대학교산학협력단 , 강원대학교산학협력단
CPC classification number: A61K8/36 , A61K8/342 , A61K8/37 , A61K8/97 , A61K2800/72 , A61K2800/82 , A61Q5/10 , A61Q17/04
Abstract: The present invention relates to an oxidized hair dye composition comprising an oxidized hair dye, a sunscreen, and at least one selected among natural substances, a calendula extract, a Ulmus macrocarpa extract, a Scutellaria baicalensis extract. More specifically, since the hair dye composition of the present invention contains a sunscreen in addition to the existing oxidized hair dye, the composition effectively prevents an oxidized dye polymer formed on the cortex of the hair from degrading by ultraviolet rays, hence delaying the decolorization of the dyed hair; thereby expecting the effects of maintaining the color of the dyed hair for a long time. Additionally, the hair dye composition is mixed with the natural substances including calendula, Ulmus macrocarpa, and Scutellaria baicalensis, thereby preventing allergic contact dermatitis caused by irritative substances contained in the hair dye. Therefore, the oxidized hair dye manufactured by a method of the present invention can be used by a person having hypersensitive skin without side effects.
Abstract translation: 本发明涉及包含氧化染发剂，防晒剂和选自天然物质，金盏花提取物，榆树提取物，黄芩提取物中的至少一种的氧化染发组合物。 更具体地说，由于除了现有的氧化染发剂以外，本发明的染发剂组合物还含有防晒剂，因此有效地防止了形成在毛发皮质上的氧化染料聚合物因紫外线而降解，因此延迟了脱色 染发 从而期望长时间保持染发的颜色的效果。 另外，将染发剂组合物与包括金盏花，榆木，黄芩的天然物质混合，从而防止由染发剂中含有的刺激物质引起的过敏性接触性皮炎。 因此，通过本发明的方法制造的氧化染发剂可以由具有过敏皮肤的人使用而没有副作用。
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公开(公告)号：KR1020140098503A
公开(公告)日：2014-08-08
申请号：KR1020130011257
申请日：2013-01-31
Applicant: 주식회사 세바바이오텍 , 서원대학교산학협력단 , 강원대학교산학협력단
Abstract: The present invention relates to a decompression-recirculation high-speed steaming device and a method for producing ginseng having an increased low-molecular ginsenosides content and, more specifically, to a method for producing the ginseng in which the content of the low-molecular ginsenosides such as Rh2, Rg2, Rg3, and CK is increased by inputting ginseng into the device of the present invention and steaming the inputted ginseng under a decompression condition. When steaming ginseng by using the decompression-recirculation high-speed steaming device of the present invention, an effect of rapidly producing red ginseng by effectively increasing the low-molecular ginsenosides (Rh2, Rg2, Rg3, and CK) contained in ginseng can be obtained and an effect of having a little content of benzopyrene that is a carcinogen by not going through a repetitive steaming step for a long time as in the past. Furthermore, when steaming ginseng by using the device of the present invention, a value of the ginseng can be increased by applying the method to cheap ginseng as a huge morphologic change of ginseng is not generated. Therefore, the decompression-recirculation high-speed steaming device and method for producing ginseng having the increased low-molecular ginsenosides content of the present invention can be usefully applied in not only medicine and medical supplies but also functional food and cosmetics.
Abstract translation: 本发明涉及一种减压 - 再循环高速蒸汽装置和一种生产具有增加的低分子人参皂甙含量的人参的方法，更具体地说，涉及一种生产人参的方法，其中低分子量人参皂苷的含量 通过将人参输入本发明的装置并在减压条件下蒸煮输入的人参，从而增加了Rh2，Rg2，Rg3和CK。 当通过使用本发明的减压 - 再循环高速蒸汽装置蒸人参时，可以获得通过有效增加人参中所含的低分子量人参皂甙（Rh2，Rg2，Rg3和CK）迅速生产红参的效果 并且通过与过去不经历长时间的重复蒸汽步骤，具有作为致癌物的苯并芘含量少的效果。 此外，当通过使用本发明的装置蒸制人参时，通过将该方法应用于廉价人参可以提高人参的价值，因为不会产生人参的巨大形态变化。 因此，本发明的具有增加的低分子量人参皂甙含量的人参的减压 - 再循环高速蒸汽装置和制造方法不仅可用于医药和医疗用品，还可用于功能性食品和化妆品。
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公开(公告)号：KR1020140027614A
公开(公告)日：2014-03-07
申请号：KR1020120085913
申请日：2012-08-06
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: The present invention relates to a manufacturing method of a functional coffee drink composition including fermented coffee products (coffee beans or by-products) and an extract thereof, and, more specifically, to a manufacturing method of a functional coffee drink composition including fermented liquid and fermented coffee residual extract, and a functional coffee drink composition manufactured thereby, wherein the fermented liquid is obtained by fermenting unprocessed coffee beans or coffee by-products, which are mostly discarded without being consumed, by using lactobacillus, and the fermented coffee residual extract is obtained by extracting the dried fermented coffee residue besides the fermented liquid, with ethanol. As the manufacturing method of the present invention is able to enhance elution of chlorogenic acid in the coffee through a simple process, the composition of the present invention manufactured through the method contains a large quantity of chlorogenic acid having a lipoperoxide production suppressing effect, cholesterol biosynthesis inhibition effect, an anti-oxidation activity, an anti-inflammatory effect and an anti-cancer effect, enabling the composition to be used as a functional coffee drink composition. Further, the manufacturing method of the present invention utilizes coffee beans, of which the unit price is cheap, or discarded coffee by-products to create novel health materials having functionalities, to provide an eco-friendly effect through the recycling of waste. [Reference numerals] (AA) Free radical elimination rate (%); (BB) Concentration (쨉m); (CC) Hydrothermal extract of coffee beans (Comparative example); (DD) Hydrothermal extract of coffee by-product (Comparative example)
Abstract translation: 本发明涉及一种包含发酵咖啡产品（咖啡豆或副产物）及其提取物的功能性咖啡饮料组合物的制造方法，更具体地，涉及包含发酵液体的功能性咖啡饮料组合物的制造方法， 发酵咖啡残余提取物和由此制造的功能性咖啡饮料组合物，其中，所述发酵液体通过使用乳杆菌发酵未处理大部分被废弃而未被消耗的未加工咖啡豆或咖啡副产物而获得，所述发酵咖啡残余提取物为 通过用乙醇萃取除了发酵液之外的干燥的发酵咖啡残渣获得。 由于本发明的制造方法能够通过简单的方法提高咖啡中的绿原酸的洗脱，所以通过该方法制造的本发明的组合物含有大量具有脂肪过氧化物产生抑制作用的绿原酸，胆固醇生物合成 抑制效果，抗氧化活性，抗炎作用和抗癌作用，使得该组合物可用作功能性咖啡饮料组合物。 此外，本发明的制造方法利用单价廉价的咖啡豆或者丢弃的咖啡副产品来制造具有功能的新型健康材料，通过废物的再循环来提供环保效果。 （标号）（AA）自由基消除率（％）; （BB）浓度（쨉m）; （CC）咖啡豆水热提取物（比较例）; （DD）咖啡副产物水热提取物（比较例）
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Patent Agency Ranking
公开(公告)号：KR1020140013800A
公开(公告)日：2014-02-05
申请号：KR1020120082332
申请日：2012-07-27
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
IPC: A23L19/00 , A23L1/30 , A61K36/258 , A61K8/97
CPC classification number: A61K36/258 , A23L33/105 , A61K8/97 , A61K36/344 , A61K36/539 , A61K2236/39 , A61K2800/85 , A61Q19/00
Abstract: The present invention relates to a method for enhancing the content of bioactive substances of a natural substance using simultaneous middle temperature extraction and a fermentation process and more specifically, in the present invention, since natural substances are fermented at 45-70°C using Bacillus coagulans, which is an edible thermophilic bacterium, and extracted at the same time, the content of effective bioactive substances is enhanced compared to the content thereof obtained by traditional fermentation, and an economic effect can be increased as the entire time required for the process is shortened. Thus, the effective bioactive substances can be effectively extracted from natural substances which have undergone simultaneous middle temperature extraction and fermentation and can be used for manufacturing health functional foods, pharmaceutical products, and cosmetics.
Abstract translation: 本发明涉及使用同时中温提取和发酵方法提高天然物质生物活性物质含量的方法，更具体地说，在本发明中，由于天然物质在45-70℃下使用凝结芽孢杆菌 ，这是一种可食用的嗜热细菌，同时提取，与传统发酵得到的含量相比，有效生物活性物质的含量增加，并且缩短了整个过程所需的整个时间，可以提高经济效果 。 因此，有效的生物活性物质可以从经过同时中温提取和发酵的天然物质中有效提取，并可用于制造健康功能性食品，药品和化妆品。
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公开(公告)号：KR101527076B1
公开(公告)日：2015-06-09
申请号：KR1020130032052
申请日：2013-03-26
Applicant: 주식회사 서울화장품 , 주식회사 세바바이오텍 , 서원대학교산학협력단 , 강원대학교산학협력단
Abstract: 본발명은일반적으로사용되는산화형염료에자외선차단제및 천연물질인금잔화, 유근피및 황금추출물에서선택된 1종이상이함유된산화형염모제조성물에관한것으로서, 보다구체적으로본 발명의산화염모제조성물은기존의산화형염모제에자외선차단제를함유함으로써모발의모피질속에형성된산화형염료중합체가자외선에의하여분해되는것을효과적으로억제하여모발에염색된색상이퇴색되는것을지연시켜염색된색상이오래유지되는효과를기대할수 있다. 또한, 천연물질인금잔화, 유근피및 황금성분을배합시켜상기염모제에포함되어있는자극성성분으로인한알레르기접촉성피부염의발생이방지된다. 따라서본 발명의방법으로제조된산화형염모제는과민성피부를가진사람도부작용없이사용할수 있다.
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公开(公告)号：KR101440469B1
公开(公告)日：2014-09-17
申请号：KR1020120082318
申请日：2012-07-27
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: 본 발명은 복합 균주를 이용한 산삼배양근 발효물의 제조방법 및 상기 발효물을 함유한 기능성 화장료 조성물에 관한 것으로서, 보다 구체적으로 본 발명은 락토바실러스 에시도필러스(
Lactobacillus acidophilus ), 비피도박테리아 롱검(
Bifidobacterium Longum ) 및 락토바실러스 람노서스 HK-9(
Lactobacillus rhamnosus HK-9)으로 이루어진 군 중에서 선택되는 하나 이상의 균주를 이용하여 발효시킨 산삼배양근의 발효 추출물을 유효성분으로 포함하고 상기 발효 추출물은 화장료 조성물 총 중량에 대하여 0.001~20 중량%로 포함된 화장료 조성물; 및 (a) 산삼배양근과 MRS 배양 배지를 1:10 중량비로 혼합하는 단계; (b) 락토바실러스 람노서스 HK-9(
Lactobacillus rhamnosus HK-9)를 상기 배양 배지의 5 중량%의 농도로 접종하고 24시간 동안 배양하는 단계; (c) 락토바실러스 에시도필러스(
Lactobacillus acidophilus )를 추가로 접종하고, 멸균된 MRS 배지를 250ml 첨가한 다음, 12시간 동안 배양 하는 단계; 및 (d) 멸균된 MRS 배지 250ml을 추가로 첨가한 후, 비피도박테리아 롱검(
Bifidobacterium Longum ) 균주를 접종하고 24시간 동안 배양하면서 발효시키는 단계를 포함하는 산삼배양근의 발효물을 제조하는 방법에 관한 것으로서, 본 발명의 방법으로 제조된 산삼배양근의 발효물은 베타-글루코시다제 효소의 활성을 증진시켜 발효물 내에 Rg3, Rh2 및 Compound K 함량을 증진시킬 수 있어 피부미백 및 주름개선을 위한 화장품의 제조에 사용할 수 있는 효과가 있다.-
公开(公告)号：KR101388918B1
公开(公告)日：2014-05-07
申请号：KR1020120055971
申请日：2012-05-25
Applicant: 강원대학교산학협력단 , 주식회사 세바바이오텍 , 서원대학교산학협력단
Abstract: 본발명은인체에서유래한유산균락토바실러스람노서스() HK-9 및그 활용방안에관한것으로, 더욱상세하게는천연물발효를통해생리활성증진활성을가질뿐 아니라미백효과및 노화방지와관련된항산화효능까지갖는유산균락토바실러스람노서스 HK-9와그를이용한발효물및 화장제품에관한것이다. 본발명에따른유산균은일반식품이아닌인체에서유래한균주이기때문에식품발효뿐만아니라미백등의활성에매우효과적이다. 이를통해기존의천연물에서용출되지않거나매우적은양이용출되어발효효율이떨어지는문제점을극복하여유효물질을효과적으로용출할수 있고, 화장품의원료로서의효과까지거둘수 있다.
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10.发明公开
公开(公告)号：KR1020140013795A
公开(公告)日：2014-02-05
申请号：KR1020120082304
申请日：2012-07-27
Applicant: 강원대학교산학협력단 , 서원대학교산학협력단 , 주식회사 세바바이오텍
Abstract: The present invention relates to a cosmetic composition for anti-wrinkle, skin whitening, and anti-acne effects which includes ginsenoside F2 as an active ingredient. The ginsenoside F2 of the present invention has: anti-wrinkle effects by promoting fibroblast proliferation, increasing collagen synthesis, and hindering elastase; skin whitening effects by suppressing melanin synthesis and tyrosinase; and acne improving effects through antibiosis activities for propionebacteriumacne which is a pathogen related to acne and staphylococcusaureus which is a suppurative bacterium so that the composition of the present invention including the ginsenoside F2 as the active ingredient can effectively improve anti-wrinkle, skin whitening, and anti-acne effects and be used as a functional cosmetic composition. [Reference numerals] (AA) Activity of suppressing melanin synthesis (%); (BB) Concentration of ginsenoside F2 (%)
Abstract translation: 本发明涉及包含人参皂苷F2作为有效成分的抗皱，皮肤美白，抗痤疮效果的化妆品组合物。 本发明的人参皂苷F2具有通过促进成纤维细胞增殖，增加胶原合成和阻碍弹性蛋白酶的抗皱作用; 通过抑制黑色素合成和酪氨酸酶的皮肤美白效果; 以及作为与痤疮和金黄色葡萄球菌相关的作为脓毒性细菌的病原体的丙酸杆菌素的抗生素活性的痤疮改善效果，使得包含人参皂甙F2作为活性成分的本发明的组合物能够有效地改善抗皱，皮肤美白和 抗痤疮效果，并用作功能性化妆品组合物。 （AA）抑制黑色素合成的活性（％） （BB）人参皂苷F2浓度（％）
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