公开(公告)号：WO2011002179A3

公开(公告)日：2011-05-19

申请号：PCT/KR2010004144

申请日：2010-06-25

Applicant: AMOREPACIFIC CORP ,  KIM DONG HYUN ,  PARK JUN SEONG ,  YU SUN HYE ,  KWEON DAE HYUK ,  KOH HYUN JU ,  PARK WON SEOK ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： KIM DONG HYUN ,  PARK JUN SEONG ,  YU SUN HYE ,  KWEON DAE HYUK ,  KOH HYUN JU ,  PARK WON SEOK ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K8/97 ,  A61Q19/08

CPC classification number: A61K36/73 ,  A61K8/97 ,  A61Q19/08

Abstract: The present invention relates to a cosmetic composition containing a Rubus coreanus extract as an active ingredient, and more particularly, to a cosmetic composition which contains a Rubus coreanus extract processed by a traditional Korean medicinal processing technique to inhibit the formation of SNARE complexes and to inhibit the release of neurotransmitters, thereby achieving excellent effects in diminishing skin wrinkles. The cosmetic composition of the present invention has superior stability in formations as compared to conventional anti-wrinkle formulations, and exhibits effects similar to those of Botox injections which have been used in conventional surgical anti-wrinkle procedures, thus remarkably diminishing skin wrinkles with no side effects.

Abstract translation: 本发明涉及一种含有芦荟提取物作为活性成分的化妆品组合物，更具体地说，涉及含有通过韩国传统药物加工技术处理的Rubus coreanus提取物以抑制SNARE复合物的形成并抑制 释放神经递质，从而在减少皮肤皱纹方面实现优异的效果。 本发明的化妆品组合物与常规抗皱配方相比，在地层中具有优异的稳定性，并且具有与用于常规手术抗皱作用的肉毒杆菌素注射剂相似的效果，因此无侧面的皮肤皱纹显着减少 效果。

公开(公告)号：WO2010123246A2

公开(公告)日：2010-10-28

申请号：PCT/KR2010002442

申请日：2010-04-20

Applicant: AMOREPACIFIC CORP ,  KWON SUNSANG ,  HAN GO UN ,  KIM EUN JOO ,  KIM DUCK HEE ,  KIM HAN-KON

Inventor： KWON SUNSANG ,  HAN GO UN ,  KIM EUN JOO ,  KIM DUCK HEE ,  KIM HAN-KON

IPC: A61K8/97 ,  A61K8/02 ,  A61Q19/00

CPC classification number: A61Q19/00 ,  A61K8/022 ,  A61K8/97 ,  A61K2800/28 ,  A61Q1/02

Abstract: The present invention relates to a cosmetic composition containing white ginseng powder. Applying cosmetics containing white ginseng powder to the skin of a user stimulates blood circulation and exhibits superior skin scrubbing effects.

Abstract translation: 本发明涉及含有白参粉末的化妆品组合物。 将含有白参粉末的化妆品应用于使用者的皮肤刺激血液循环，并具有优异的皮肤擦洗效果。

公开(公告)号：WO2010058986A3

公开(公告)日：2010-09-30

申请号：PCT/KR2009006839

申请日：2009-11-19

Applicant: AMOREPACIFIC CORP ,  PARK JUN SEONG ,  KIM DONG HYUN ,  PARK NOK HYUN ,  PARK HYE YOON ,  LEE JAE KYOUNG ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： PARK JUN SEONG ,  KIM DONG HYUN ,  PARK NOK HYUN ,  PARK HYE YOON ,  LEE JAE KYOUNG ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K8/97 ,  A61Q19/00

CPC classification number: A61K8/97 ,  A61K2800/522 ,  A61Q19/00

Abstract: Disclosed herein is a cosmetic composition containing, as an active ingredient, a mixture of extracts of honey-roasted Adenophora triphylla var. japonica Hara and honey-roasted Angelica tenuissima Nakai, processed using a medicinal herb processing technique, and of extracts of medicinal herbs such as Lycium chinense Mill or Paeonia suffruticosa, and thus shows excellent antioxidant and skin-moisturizing effects.

Abstract translation: 本文公开了一种化妆品组合物，其含有作为活性成分的蜂蜜焙烧的Adenophora triphylla var。 茉莉花和蜜饯当归，使用药草加工技术，以及枸杞子或芍药等药用植物提取物，因此显示出优异的抗氧化和保湿作用。

公开(公告)号：WO2012067404A3

公开(公告)日：2012-09-07

申请号：PCT/KR2011008700

申请日：2011-11-15

Applicant: AMOREPACIFIC CORP ,  LEE OK CHAN ,  RHO HO SIK ,  HWANG KYEONG HWAN ,  CHO GA YOUNG ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： LEE OK CHAN ,  RHO HO SIK ,  HWANG KYEONG HWAN ,  CHO GA YOUNG ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K36/282 ,  A61K8/97 ,  A61P17/00 ,  A61Q19/00

CPC classification number: A61K36/282 ,  A61K8/97 ,  A61Q19/08

Abstract: A composition for anti-aging containing Artemisia annua L. as an active ingredient of the present invention does not cause any side effects on the skin, and can be usefully applied to an external preparation for the skin for anti-aging and improving wrinkles due to superior effectiveness in accelerating biosynthesis of skin cells and collagen.

Abstract translation: 作为本发明的有效成分含有青蒿的抗衰老用组合物不会对皮肤造成副作用，可以有效地用于皮肤外用剂中，用于抗衰老和改善由于 在加速皮肤细胞和胶原蛋白的生物合成方面具有卓越的效果。

公开(公告)号：WO2011025176A3

公开(公告)日：2011-07-14

申请号：PCT/KR2010005457

申请日：2010-08-18

Applicant: AMOREPACIFIC CORP ,  KIM DONG HYUN ,  PARK JUN SEONG ,  CHANG HUI KYEUNG ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： KIM DONG HYUN ,  PARK JUN SEONG ,  CHANG HUI KYEUNG ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K8/97 ,  A61K36/258 ,  A61K36/288 ,  A61Q19/08

CPC classification number: A61Q19/00 ,  A61K8/97 ,  A61K36/232 ,  A61K36/258 ,  A61K36/288 ,  A61K36/71 ,  A61K36/8945 ,  A61K2800/87 ,  A61K2300/00

Abstract: Disclosed is a method capable of improving the skin regeneration effect of medicinal materials through double boiling using an earthenware pot. The method shows an excellent skin regeneration effect, and the extract of medicinal materials obtained therethrough can be variously applied in the fields of cosmetics, health foods or medicine.

Abstract translation: 公开了能够通过使用陶器锅通过双沸腾改善药材的皮肤再生效果的方法。 该方法显示出优异的皮肤再生效果，通过其获得的药用材料的提取物可以各种应用于化妆品，保健食品或药物领域。

公开(公告)号：WO2010137882A3

公开(公告)日：2011-04-14

申请号：PCT/KR2010003348

申请日：2010-05-27

Applicant: AMOREPACIFIC CORP ,  HK BIOTECH CO LTD ,  YEOM MYEONG HUN ,  PARK WON SEOK ,  KIM DUCK HEE ,  KIM HAN KON ,  KIM JEONG OK

Inventor： YEOM MYEONG HUN ,  PARK WON SEOK ,  KIM DUCK HEE ,  KIM HAN KON ,  KIM JEONG OK

IPC: A61K8/97 ,  A61K36/14 ,  A61Q19/02 ,  A61Q19/08

CPC classification number: A61K36/14 ,  A61K8/73 ,  A61K8/97 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to a composition to be externally applied to the skin, containing Chamaecyparis obtusa polysaccharides as active ingredients, and more particularly, to a composition to be externally applied to the skin, which contains Chamaecyparis obtusa polysaccharides to not only promote collagen production, improve skin elasticity, diminish wrinkles, inhibit melanogenesis and thus achieve excellent skin-whitening effects, but to also promote keratinocyte differentiation, improve skin moisturizing effects, and achieve superior anti-inflammatory and skin regeneration effects.

Abstract translation: 本发明涉及外用于皮肤的组合物，其含有作为活性成分的Chamaecyparis obtusa多糖，更具体地，涉及外用于皮肤的组合物，其含有Chamaecyparis obtusa多糖以不仅促进胶原产生， 改善皮肤弹性，减少皱纹，抑制黑色素生成，从而达到优异的美白效果，同时也促进角质细胞分化，改善皮肤保湿效果，达到优异的抗炎和皮肤再生效果。

公开(公告)号：WO2010098595A2

公开(公告)日：2010-09-02

申请号：PCT/KR2010001180

申请日：2010-02-25

Applicant: AMOREPACIFIC CORP ,  RHO HO SIK ,  KIM EUN JOO ,  CHO GA YOUNG ,  PARK HYE YOON ,  KIM JI SEONG ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： RHO HO SIK ,  KIM EUN JOO ,  CHO GA YOUNG ,  PARK HYE YOON ,  KIM JI SEONG ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K8/97 ,  A61Q19/00 ,  A61Q19/08

CPC classification number: A61K8/97 ,  A61Q19/08

Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.

Abstract translation: 本发明涉及含有松根提取物的皮肤外用组合物。 更具体地，根据本发明的皮肤外用组合物含有作为活性成分的松果提取物，其显示各种效果，包括消除自由基，保护细胞膜免受紫外线辐射的损伤，抑制反应性的生成 由紫外线引起的氧物质，抑制由紫外线辐射引起的超氧化物歧化酶（SOD）和过氧化氢酶的表达的降低，刺激HSP70的产生以保护细胞，抑制由UV辐射引起的MMP-2生物合成，诱导SIRT1的表达 基因，其恢复DNA损伤，并诱导维持核膜结构的LMNA1基因的表达。 最终，本发明的组合物可防止皮肤老化。

公开(公告)号：WO2010058936A3

公开(公告)日：2010-08-19

申请号：PCT/KR2009006744

申请日：2009-11-17

Applicant: AMOREPACIFIC CORP ,  PARK JUN SEONG ,  PARK HYE YOON ,  KIM DONG HYUN ,  LEE SANG MIN ,  SHIN DONG WOOK ,  KIM SHIN HYOUNG ,  NOH MIN SOO ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： PARK JUN SEONG ,  PARK HYE YOON ,  KIM DONG HYUN ,  LEE SANG MIN ,  SHIN DONG WOOK ,  KIM SHIN HYOUNG ,  NOH MIN SOO ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K31/366 ,  A61K31/352 ,  A61P17/00

CPC classification number: A61K31/352 ,  A61K9/0014 ,  A61K31/366

Abstract: Disclosed herein is a skin external composition for inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases, which contains ortho-dihydroxyisoflavone derivatives as an active ingredient. Specifically, the skin external composition contains the ortho-dihydroxyisoflavone derivatives, 4',6,7-trihydroxyisoflavone, 3',4',7-trihydroxyisoflavone or a mixture thereof, and thus increases the expression of DKK3 protein and FZD1 protein, which appropriately control Wnt signaling, thereby inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases caused by epidermal hyperproliferation.

Abstract translation: 本文公开了一种皮肤外用组合物，其用于抑制表皮过度增殖并减轻含有邻二羟基异黄酮衍生物作为活性成分的炎性皮肤病。 具体地说，皮肤外用组合物含有邻二羟基异黄酮衍生物，4'，6,7-三羟基异黄酮，3'，4'，7-三羟基异黄酮或其混合物，从而增加了DKK3蛋白和FZD1蛋白的表达， 控制Wnt信号，从而抑制表皮过度增殖并减轻由表皮过度增殖引起的炎性皮肤病。

公开(公告)号：WO2011159092A9

公开(公告)日：2012-03-01

申请号：PCT/KR2011004361

申请日：2011-06-14

Applicant: AMOREPACIFIC CORP ,  SNU R&DB FOUNDATION ,  PARK JUN SEONG ,  KIM DUCK HEE ,  KIM HAN KON ,  KIM EUN MI ,  KIM BYUNG GEE

Inventor： PARK JUN SEONG ,  KIM DUCK HEE ,  KIM HAN KON ,  KIM EUN MI ,  KIM BYUNG GEE

IPC: C12N1/20 ,  C12N9/02 ,  C12N15/53 ,  C12P17/06

CPC classification number: C12P33/20 ,  C12N1/20 ,  C12N9/0004 ,  C12P17/06 ,  C12P19/02 ,  C12P33/00 ,  C12R1/41 ,  Y02P20/52

Abstract: The present invention relates to the novel Rhizobium sp. GIN611 KCTC11708BP or to cell extracts thereof, to a novel oxidoreductase which exhibits a glycolytic activity, to a gene encoding the oxidoreductase, to a recombinant strain comprising recombinant vector proteins or to an expression vector encoding recombinant proteins, and to a method for the glycolysis of natural products using same as a biocatalyst. The present invention also relates to a method for producing aglycones from a variety of natural products using same. The novel oxidoreductase separated from the novel microorganism of the present invention does not belong to a glucosidase group but belongs to an oxidoreductase group, and has a glycolytic activity for natural products. The novel oxidoreductase oxidizes the sugar in the aglycones of natural products, thereby producing a variety of aglycones.

Abstract translation: 本发明涉及新根瘤菌属（Rhizobium sp。） GIN611KCTC11708BP或其细胞提取物，对具有糖酵解活性的新型氧化还原酶，与编码该氧化还原酶的基因相连，包含重组载体蛋白的重组菌株或编码重组蛋白的表达载体，以及糖酵解方法 使用与生物催化剂相同的天然产物。 本发明还涉及使用它们的各种天然产物制备糖苷配基的方法。 从本发明的新型微生物分离的新型氧化还原酶不属于葡萄糖苷酶基团，属于氧化还原酶基团，对天然产物具有糖酵解活性。 新型氧化还原酶氧化天然产物的糖苷配基中的糖，从而产生各种糖苷配基。

公开(公告)号：WO2012002730A2

公开(公告)日：2012-01-05

申请号：PCT/KR2011004755

申请日：2011-06-29

Applicant: AMOREPACIFIC CORP ,  KIM DONG HYUN ,  PARK JUN SEONG ,  SHIM JIN SUP ,  KIM DUCK HEE ,  KIM HAN KON

Inventor： KIM DONG HYUN ,  PARK JUN SEONG ,  SHIM JIN SUP ,  KIM DUCK HEE ,  KIM HAN KON

IPC: A61K8/98 ,  A61Q19/00 ,  A61Q19/02

CPC classification number: A61K8/987 ,  A61Q19/00 ,  A61Q19/02

Abstract: The present invention relates to a composition which contains bee venom extracts as active ingredients and thus has skin-whitening and skin-moisturizing effects. In addition, the present invention relates to a cosmetic composition which contains bee venom extracts as active ingredients and thus has skin-whitening and skin-moisturizing effects.

Abstract translation: 本发明涉及含有蜂毒提取物作为活性成分并因此具有皮肤增白和皮肤增湿作用的组合物。 另外，本发明涉及含有蜂毒提取物作为活性成分并因此具有皮肤增白和皮肤增湿作用的化妆品组合物。