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    INTEGRATED SENSORS
    1.
    发明申请
    INTEGRATED SENSORS 有权
    集成传感器

    公开(公告)号：US20140028995A1

    公开(公告)日：2014-01-30

    申请号：US13452218

    申请日：2012-04-20

    Applicant: Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

    Inventor： Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

    IPC: G01N21/01

    CPC classification number: G01N21/01 ,  G01N21/648 ,  G01N21/658

    Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a flexible substrate, and an array of spaced apart sensing members formed on a surface of the flexible substrate. Each of the spaced apart sensing members includes a plurality of polygon assemblies. The polygon assemblies are arranged in a controlled pattern on the surface of the flexible substrate such that each of the plurality of polygon assemblies is a predetermined distance from each other of the plurality of polygon assemblies, and each of the plurality of polygon assemblies including collapsible signal amplifying structures controllably positioned in a predetermined geometric shape.

    Abstract translation: 本文公开了集成传感器的示例。 集成传感器的示例包括柔性基板和形成在柔性基板的表面上的间隔开的感测部件阵列。 每个间隔开的感测构件包括多个多边形组件。 多边形组件以可控的图案布置在柔性基板的表面上，使得多个多边形组件中的每一个距离多个多边形组件中的彼此之间是预定距离，并且多个多边形组件中的每一个包括可折叠信号 放大结构可控地定位在预定的几何形状。

    RAMAN SPECTROSCOPY
    2.
    发明申请
    RAMAN SPECTROSCOPY 审中-公开
    拉曼光谱

    公开(公告)号：US20130278929A1

    公开(公告)日：2013-10-24

    申请号：US13451290

    申请日：2012-04-19

    Applicant: Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

    Inventor： Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

    IPC: G01J3/44

    CPC classification number: G01J3/44 ,  G01J3/021 ,  G01N21/658

    Abstract: Apparatus, methods, and hollow metal waveguides to perform surface-enhanced Raman spectroscopy are disclosed. An example apparatus includes a hollow metal waveguide to direct Raman photons from an intermediate location within a volume of the hollow metal waveguide toward a distal end of the hollow metal waveguide, and a mirror to direct incident light from a light source to the intermediate location within the volume of the hollow metal waveguide and to direct at least some of the Raman photons toward the distal end.

    Abstract translation: 公开了用于执行表面增强拉曼光谱的装置，方法和中空金属波导。 示例性装置包括中空金属波导，以将拉曼光子从中空金属波导的体积内的中间位置引向中空金属波导的远端，以及反射镜，用于将来自光源的入射光引导到中间金属波导的中间位置 中空金属波导的体积并且将至少一些拉曼光子引向远端。

    VIBRATING TIP SURFACE ENHANCED RAMAN SPECTROSCOPY
    4.
    发明申请
    VIBRATING TIP SURFACE ENHANCED RAMAN SPECTROSCOPY 有权
    振动提示表面增强拉曼光谱

    公开(公告)号：US20110188035A1

    公开(公告)日：2011-08-04

    申请号：US12697156

    申请日：2010-01-29

    Applicant: Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

    Inventor： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

    IPC: G01J3/44

    CPC classification number: G01J3/44

    Abstract: A vibrating tip surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a nano-needle configured to vibrate. The apparatus includes the nano-needle with a substantially sharp tip at a free end opposite an end attached to a substrate. The tip is configured to adsorb an analyte. The apparatus further includes a vibration source configured to provide an alternating current (AC) electric field that induces a vibration of the free end and the tip of the nano-needle. Vibration of the nano-needle under the influence of the AC electric field facilitates detection of a Raman scattering signal from the analyte adsorbed on the nano-needle tip. The system further includes a synchronous detector configured to be gated cooperatively with the vibration of the nano-needle. The method includes inducing the vibration, illuminating the vibrating tip to produce a Raman signal, and detecting the Raman signal using the detector.

    Abstract translation: 振动尖端表面增强拉曼光谱（SERS）装置，系统和方法采用配置为振动的纳米针。 该装置包括在与连接到基底的端相对的自由端处具有基本尖锐的尖端的纳米针。 尖端构造成吸附分析物。 该装置还包括一个被配置为提供交流（AC）电场的振动源，其引起自由端和纳米针的尖端的振动。 在AC电场的影响下，纳米针的振动有助于检测吸附在纳米针尖上的分析物的拉曼散射信号。 该系统还包括配置为与纳米针的振动协同地选通的同步检测器。 该方法包括引起振动，照亮振动尖端以产生拉曼信号，并使用检测器检测拉曼信号。

    Plasmonic electric-field concentrator arrays and systems for performing raman spectroscopy
    5.
    发明申请
    Plasmonic electric-field concentrator arrays and systems for performing raman spectroscopy 失效
    等离子体电场集中器阵列和用于执行拉曼光谱的系统

    公开(公告)号：US20100091274A1

    公开(公告)日：2010-04-15

    申请号：US12287549

    申请日：2008-10-10

    Applicant: Alexandre M. Bratkovski ,  Ekaterina Viktorovna Ponizovskaya ,  Zhiyong Li

    Inventor： Alexandre M. Bratkovski ,  Ekaterina Viktorovna Ponizovskaya ,  Zhiyong Li

    IPC: G01J3/44 ,  G01N21/55

    CPC classification number: G01N21/658

    Abstract: Various embodiments of the present invention relate to plasmonic electric-field concentrators and to systems incorporating the plasmonic electric-field concentrators to perform Raman spectroscopy. In one aspect, a plasmonic electric-field concentrator comprises two or more large features, and a relatively small feature similar in shape to large features positioned adjacent to the two or more large features. The features are arranged so that when light of an appropriate wavelength is incident on the features, surface plasmon polaritons form on the outer surfaces of the features. The surface plasmon polaritons have associated electric fields extending perpendicular to the surfaces of the features. The electric fields are concentrated in the space between features forming an electric field hot spot that enhances Raman scattered light emitted from an analyte proximate to or absorbed on the features.

    Abstract translation: 本发明的各种实施例涉及等离子体电场集中器以及结合等离子体激元集中器以执行拉曼光谱的系统。 一方面，等离子体电场集中器包括两个或更多个大特征，以及与形状相邻的相对较小的特征，其尺寸与两个或更多个特征邻近的大特征相似。 特征被布置成使得当适当波长的光入射到特征上时，在特征的外表面上形成表面等离子体激元。 表面等离子体激元极化子具有垂直于特征表面延伸的相关电场。 电场集中在形成电场热点的特征之间的空间中，其增强了从附近或被吸收在特征上的分析物发射的拉曼散射光。

    Raman signal-enhancing structures and Raman spectroscopy systems including such structures
    6.
    发明授权
    Raman signal-enhancing structures and Raman spectroscopy systems including such structures 有权
    包括这种结构的拉曼信号增强结构和拉曼光谱系统

    公开(公告)号：US07391511B1

    公开(公告)日：2008-06-24

    申请号：US11700986

    申请日：2007-01-31

    Applicant: Alexandre M. Bratkovski ,  Shih-Yuan Wang ,  Zhiyong Li

    Inventor： Alexandre M. Bratkovski ,  Shih-Yuan Wang ,  Zhiyong Li

    IPC: G01J3/44 ,  G01N21/65

    CPC classification number: G01N21/658

    Abstract: A Raman signal-enhancing structure includes a substrate and a plurality of protrusions located at predetermined positions relative to a surface of the substrate. Each protrusion includes a Raman signal-enhancing material and has cross-sectional dimensions of less than about 50 nanometers. The structure also includes an edge that includes an intersection between two nonparallel surfaces of at least one protrusion. A Raman spectroscopy system includes such a Raman signal-enhancing structure, and Raman spectroscopy may be performed on an analyte using such structures and systems. A method for forming such a Raman signal-enhancing structure includes nanoimprint lithography.

    Abstract translation: 拉曼信号增强结构包括基板和位于相对于基板的表面的预定位置处的多个突起。 每个突起包括拉曼信号增强材料并且具有小于约50纳米的横截面尺寸。 该结构还包括边缘，其包括至少一个突起的两个不平行表面之间的交叉点。 拉曼光谱系统包括这样的拉曼信号增强结构，并且可以使用这种结构和系统对分析物进行拉曼光谱。 形成这种拉曼信号增强结构的方法包括纳米压印光刻。

    Integrated sensors
    7.
    发明授权
    Integrated sensors 有权
    集成传感器

    公开(公告)号：US09453793B2

    公开(公告)日：2016-09-27

    申请号：US13452218

    申请日：2012-04-20

    Applicant: Alexandre M Bratkovski ,  R Stanley Williams ,  Zhiyong Li

    Inventor： Alexandre M Bratkovski ,  R Stanley Williams ,  Zhiyong Li

    IPC: G01N21/00 ,  G01N21/01 ,  G01N21/65 ,  G01N21/64

    CPC classification number: G01N21/01 ,  G01N21/648 ,  G01N21/658

    Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a flexible substrate, and an array of spaced apart sensing members formed on a surface of the flexible substrate. Each of the spaced apart sensing members includes a plurality of polygon assemblies. The polygon assemblies are arranged in a controlled pattern on the surface of the flexible substrate such that each of the plurality of polygon assemblies is a predetermined distance from each other of the plurality of polygon assemblies, and each of the plurality of polygon assemblies including collapsible signal amplifying structures controllably positioned in a predetermined geometric shape.

    Abstract translation: 本文公开了集成传感器的示例。 集成传感器的示例包括柔性基板和形成在柔性基板的表面上的间隔开的感测部件阵列。 每个间隔开的感测构件包括多个多边形组件。 多边形组件以可控的图案布置在柔性基板的表面上，使得多个多边形组件中的每一个距离多个多边形组件中的彼此之间是预定距离，并且多个多边形组件中的每一个包括可折叠信号 放大结构可控地定位在预定的几何形状。

    APPARATUS FOR PERFORMING A SENSING APPLICATION
    8.
    发明申请
    APPARATUS FOR PERFORMING A SENSING APPLICATION 有权
    执行感应应用的装置

    公开(公告)号：US20150116706A1

    公开(公告)日：2015-04-30

    申请号：US14394287

    申请日：2012-04-24

    Applicant: Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

    Inventor： Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

    IPC: G01N21/65

    CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01N2201/06113 ,  Y10S977/954

    Abstract: An apparatus for performing a sensing application includes a reservoir to contain a solution, a dispenser to dispense the solution from the reservoir, and a substrate having a plurality of nano-fingers positioned to receive the dispensed solution, in which the plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus also includes an illumination source to illuminate the received solution, an analyte introduced around the plurality of nano-fingers, and the plurality of nano-fingers, in which light is to be emitted from the analyte in response to being illuminated. The apparatus further includes a detector to detect the light emitted from the analyte.

    Abstract translation: 用于执行感测应用的装置包括容纳溶液的储存器，用于从储存器分配溶液的分配器以及具有多个纳米手指的基板，该多个纳米手指定位成接收分配的溶液，其中多个纳米手指 是柔性的，使得多个纳米手指可相对于彼此配置。 所述装置还包括照亮所接收的溶液的照明源，围绕所述多个纳米手指引入的分析物和所述多个纳米手指，其中光将响应于被照亮从分析物发射。 该装置还包括检测器，用于检测从分析物发射的光。

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