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1.发明申请METHODS FOR THE INACTIVATION OF MICROORGANISMS IN BIOLOGICAL FLUIDS, FLOW THROUGH REACTORS AND METHODS OF CONTROLLING THE LIGHT SUM DOSE TO EFFECTIVELY INACTIVATE MICROORGANIMS IN BATCH REACTORS 审中-公开生物流体中微生物灭活的方法，通过反应器流动的方法和控制轻剂量以有效地灭菌反应器中的微生物体的方法
公开(公告)号：WO2006021314A8
公开(公告)日：2006-05-18
申请号：PCT/EP2005008467
申请日：2005-08-04
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
Inventor： ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
CPC classification number: A61L2/10 , A23L3/26 , A23L3/28 , A61L2/0011 , A61L2/28 , G01N21/33 , H05B3/0052
Abstract: The present invention relates to a method for determining an effective dose of monochromatic or polychromatic light from one or more light sources to inactivete microorganisms present in a biological fluid, preferably a non-trannsparent fluid. Moreover, there is provided a method for the inactivation of microorganism in a biological fluid in a flow-through-reactor. Moreover, the invention advantageously provides a flow-through-reactor with one or more thermostated light sources. The invention further provides a method of controlling the light sum dose of monochromatic or polychromatic light emitted from one or more light sources to effectively inactivate microorganisms present in a biological fluid in a batch reactor.
Abstract translation: 本发明涉及一种用于确定来自一种或多种光源的单色或多色光的有效剂量以使存在于生物流体，优选非透明流体中的微生物灭活的方法。 此外，提供了在流通反应器中的生物流体中的微生物灭活的方法。 此外，本发明有利地提供具有一个或多个恒温光源的流通反应器。 本发明还提供一种控制从一个或多个光源发射的单色或多色光的光总量的方法，以有效地灭活间歇反应器中存在于生物流体中的微生物。
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公开(公告)号：WO2006021314A2
公开(公告)日：2006-03-02
申请号：PCT/EP2005008467
申请日：2005-08-04
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
Inventor： ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
CPC classification number: A61L2/10 , A23L3/26 , A23L3/28 , A61L2/0011 , A61L2/28 , G01N21/33 , H05B3/0052
Abstract: The present invention relates to a method for determining an effective dose of monochromatic or polychromatic light from one or more light sources to inactivete microorganisms present in a biological fluid, preferably a non-trannsparent fluid. Moreover, there is provided a method for the inactivation of microorganism in a biological fluid in a flow-through-reactor. Moreover, the invention advantageously provides a flow-through-reactor with one or more thermostated light sources. The invention further provides a method of controlling the light sum dose of monochromatic or polychromatic light emitted from one or more light sources to effectively inactivate microorganisms present in a biological fluid in a batch reactor.
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3.发明申请METHOD FOR THE VALIDATABLE INACTIVATION OF PATHOGENS IN A BIOLOGICAL FLUID BY IRRADIATION 审中-公开通过辐照在生物流体中有效灭活病原体的方法
公开(公告)号：WO2004075931A3
公开(公告)日：2004-12-23
申请号：PCT/EP2004001994
申请日：2004-02-27
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
Inventor： ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
IPC: A61L2/00 , A61L2/08 , A61L2/10 , A61L2/28 , G01J1/00 , G01J1/08 , G01J1/42 , G01J1/48 , G01N21/00
CPC classification number: G01J1/08 , A61L2/0011 , A61L2/0017 , A61L2/0052 , A61L2/10 , A61L2/28 , A61L2202/22 , A61M1/3681 , A61M1/3683 , A61M2205/053 , C02F1/32 , C02F2201/326 , G01J1/42 , G01J1/48
Abstract: A validatable method for determining a photochemically effective dose for inactivating pathogens in a fluid sample is described herein. In particular, the instant invention covers methods for determining a photochemically effective doses sufficient to inactivate pathogens in a biological sample while leaving biologically active substances of interest unaffected. A batch irradiation reactor effective for inactivating pathogens in biological samples is also described.
Abstract translation: 本文描述了用于确定用于灭活流体样品中病原体的光化学有效剂量的可验证方法。 特别地，本发明包括确定足以灭活生物样品中的病原体的光化学有效剂量同时使感兴趣的生物活性物质不受影响的方法。 还描述了有效用于灭活生物样品中的病原体的批量照射反应器。
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公开(公告)号：CA2876473C
公开(公告)日：2021-05-11
申请号：CA2876473
申请日：2013-06-13
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： MUNDT WOLFGANG , MITTERER ARTUR , REITER MANFRED , HASSLACHER MEINHARD , GRILLBERGER LEOPOLD , KREIL THOMAS
Abstract: The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m2. Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.
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公开(公告)号：IN10441DEN2014A
公开(公告)日：2015-08-21
申请号：IN10441DEN2014
申请日：2014-12-08
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： MUNDT WOLFGANG , MITTERER ARTUR , REITER MANFRED , HASSLACHER MEINHARD , GRILLBERGER LEOPOLD , KREIL THOMAS
Abstract: The invention relates to a method for removing a viral contaminant from a preparation being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further the invention relates to the use of a virus filter in filtration of at least about 24 hours wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m2. Further the invention relates to the use of a preparation being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical diagnostic and/or cosmetic preparations as well as in food preparations.
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Patent Agency Ranking
公开(公告)号：HK1108134A1
公开(公告)日：2008-05-02
申请号：HK08102015
申请日：2008-02-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
IPC: A61L20060101 , C02F20060101 , G01J20060101 , G01N20060101 , G01T20060101
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公开(公告)号：ZA201409253B
公开(公告)日：2022-05-25
申请号：ZA201409253
申请日：2014-12-15
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： MUNDT WOLFGANG , REITER MANFRED , GRILLBERGER LEOPOLD , MITTERER ARTUR , HASSLACHER MEINHARD , KREIL THOMAS
Abstract: The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m 2 . Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.
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公开(公告)号：AU2013277532A1
公开(公告)日：2015-01-15
申请号：AU2013277532
申请日：2013-06-13
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： MUNDT WOLFGANG , MITTERER ARTUR , REITER MANFRED , HASSLACHER MEINHARD , GRILLBERGER LEOPOLD , KREIL THOMAS
Abstract: The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m2. Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.
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公开(公告)号：DK2266630T3
公开(公告)日：2014-03-17
申请号：DK10009727
申请日：2004-02-27
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： ANDERLE HEINZ , MATTHIESSEN PETER , SCHWARZ HANS-PETER , TURECEK PETER , KREIL THOMAS , BOGGS DANIEL R
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公开(公告)号：CA2876473A1
公开(公告)日：2013-12-27
申请号：CA2876473
申请日：2013-06-13
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： MUNDT WOLFGANG , MITTERER ARTUR , REITER MANFRED , HASSLACHER MEINHARD , GRILLBERGER LEOPOLD , KREIL THOMAS
Abstract: The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m2. Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.
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