Abstract:
A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first and second valve chambers (282, 284) operable with the first and second valve actuators, the first and second valve chambers communicating fluidly with each other, at least the first valve chamber communicating fluidly with a compliance chamber (286), the compliance chamber negating a first backpressure due to a pneumatic closing pressure used to close the first valve chamber to help to ensure the pneumatic pressure applied to the first valve chamber will close the first valve chamber against a second backpressure from an existing closure of the second valve chamber.
Abstract:
A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first and second valve chambers (282, 284) operable with the first and second valve actuators, the first and second valve chambers communicating fluidly with each other, at least the first valve chamber communicating fluidly with a compliance chamber (286), the compliance chamber negating a first backpressure due to a pneumatic closing pressure used to close the first valve chamber to help to ensure the pneumatic pressure applied to the first valve chamber will close the first valve chamber against a second backpressure from an existing closure of the second valve chamber.
Abstract:
A system, method and apparatus for performing a renal replacement therapy is provided. In one embodiment, two small high flux dialyzers (20, 30) are connected in series. A restriction (40) is placed between the two dialyzers in the dialysate flow path (962). The restriction is variable and adjustable in one preferred embodiment. The restriction builds a positive pressure in the venous dialyzer, causing a high degree of intentional backfiltration. That backfiltration causes a significant flow of dialysate through the high flux venous membrane directly into the patient's blood. That backfiltered solution is subsequently ultrafiltered from the patient from the arterial dialyzer. The diffusion of dialysate into the venous filter and removal of dialysate from the arterial dialyzer causes a convective transport of toxins from the patient. Additionally, the dialysate that does not diffuse directly into the patient but instead flows across the membranes of both dialyzers provides a diffusive clearance of waste products.
Abstract:
A dialysis system (220) includes a diaysisinstrument (20) including a bloo pup atuatdr;a dialyzer (6); a heparin pump (152% and a dispOsable cassette (4Cflincluding a blood pnumping portion operable with the blood pump actuator of the dialysis instrument the blood pumping portion induding aninet and an outlet the inlet of the lood pumping portion of the disposable cassete poslioned and arranged to receive blood from an arterial line of an extraporeal circuit, the outlet of the blood pumping portion of the disposable cassette portioned and arranged to deliver the blood to the dialyzer and to receive heparnn from th heparin pump (1 52). Sheet 28 of 48 co :9 a.e CL n in a 41 U.e b ayz ese a a eoe LO u.C> C
Abstract:
Una máquina (10) de diálisis que comprende: un instrumento (20) de diálisis que tiene un accionador (22) de bomba y primer y segundo accionadores de válvula y una casete (40) desechable que puede funcionar con el instrumento de diálisis, incluyendo la casete desechable una parte de bomba que puede funcionar con el accionador de bomba y primera y segunda cámaras (282, 284) de válvula que pueden funcionar con los primer y segundo accionadores de válvula, caracterizada porque la casete comprende una cámara (286) de adaptabilidad en comunicación fluida con las primera y segunda cámaras de válvula, la cámara de adaptabilidad definida en parte por una membrana (288) flexible usada para cerrar al menos una de las primera y segunda cámaras de válvula, definiendo las cámaras de válvula, cada una, una abertura para comunicación fluida con la cámara de adaptabilidad.
Abstract:
A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first and second valve chambers (282, 284) operable with the first and second valve actuators, the first and second valve chambers communicating fluidly with each other, at least the first valve chamber communicating fluidly with a compliance chamber (286), the compliance chamber negating a first backpressure due to a pneumatic closing pressure used to close the first valve chamber to help to ensure the pneumatic pressure applied to the first valve chamber will close the first valve chamber against a second backpressure from an existing closure of the second valve chamber.
Abstract:
A hemodialysis machine (10) comprising a blood circuit (210); a dialysate circuit (220); a dialyzer (36) placed in communication with the blood circuit (210) and the dialysate circuit (220); and a priming sequence in which dialysate is used to prime a first portion of the dialysate circuit (220) and a physiologically compatible solution, other than dialysate, is used to prime a second portion of the dialysate circuit (220), the dialyzer (36) and the blood circuit (210). Sheet 28 of 48 to4 re U? 19a c a. @ 8@ 0 8* 8 C 08 D es-0)) >
Abstract:
A dialysis machine method wNch comprises apping a pneumatic closing pressure to a first valve chamber (282) and arranging a compliance chamber (286) to fex and absorb energy from the pneumatic dosing pressure so as to tend to prevent the pneumatic dosing pressure from opening an existing closure of a second valve chamber (284), Sheet 47 of 48 280- FIG. 73A 280 FIG. 738 288 286 283 283 286 2 83 F80G. 74. 3 282,
Abstract:
A hemodialysis system (10) includes blood tubing (44), a peristaltic blood pump contacting the blood tubing to pump blood through the blood tubing, a dialyzer (36) in fluid communication with the blood tubing, first and second peristaltic dialysate pumps (22), a dialysate heater (26), a plurality of pinch valves (48) aligned in a row, a strike plate (52), and a cassette (40) including a rigid structure, a heating portion (26), first and second dialysate pumping tubes, and a plurality of incoming tubes (38) entering the rigid structure along a same side of the cassette (40) and configured to align so as to match the row of pinch valves (48), the rigid structure when the cassette is mounted for operation orienting (i) the heating portion adjacent to the dialysate heater so that dialysate can be heated by the dialysate heater, (ii) the first and second dialysate pumping tubes adjacent to the first and second peristaltic dialysate pumps, and (iii) the plurality of incoming tubes adjacent to the plurality of pinch valves to enable the tubes to be individually closed by the pinch valves, and wherein the strike plate (52) is located across from the incoming tubes so that each of the pinch valves (48) is positioned to pinch one of the tubes against the strike plate (52). Sheet 4 of 48 FIG. 8 22f4 38 38b
Abstract:
A hemodialysis machine (10) is disclosed comprising: a blood circuit (184, 186); a dialysate circuit (220); and a dialyzer (36) placed in communication with the blood circuit and the dialysate circuit. The hemodialysis machine is operable to perform a priming sequence in which dialysate is used to prime a first portion of the dialysate circuit and a physiologically compatible solution, other than dialysate, is used to prime a second portion of the dialysate circuit, the dialyzer and the blood circuit.