Abstract:
An assay implementation in a microfluidic format in a cartridge relating to a point-of-care instrument platform for monitoring and diagnosing infectious diseases (e.g., AIDS and malaria). The platform may also provide a complete blood count. The instrument platform may hold the cartridge and a portion of an optical system for fluorescent and scattered light related analyses of blood sample in a flow channel of the cartridge.
Abstract:
A gas sensor is provided for detecting one or more gases in a gas sample. The gas sensor includes a substrate, a solid electrolyte layer including lanthanum oxide for sensing carbon dioxide, a heating element thermally coupled to the solid electrolyte layer, and a controller coupled to the heating element and the solid electrolyte layer. The controller heats the heating element so that the solid electrolyte layer reaches an operating temperature. Methods of sensing carbon dioxide and humidity are also disclosed.
Abstract:
A nanowire super-capacitor electrode for storing electrical energy. The electrode is formed by anodizing a porous membrane having a uniform pore size and diameter, depositing a metal layer on the membrane back, electroplate metal through the pores of the membrane, dissolving the porous membrane. The formed nanowire electrode is placed in an electrolyte to integrate said nanowire into an electrolytic capacitor.
Abstract:
A surface enhanced Raman scatter (SERS) analyte analyzer (10). An injector (15) may provide a spray of charged nanoparticles (19) suspended in droplets of an evaporable solution (27) into a chamber (14). When the solution (27) quickly evaporates, droplets of nanoparticles (19) are left without a supporting solution. These droplets or cloud of charged.nanoparticles (28) may then explode into a dispersion or aerosol (35). The charged nanoparticles (19) may attract molecules (36) of a sample (IS) for attachment to their surfaces. A laser light (21) may impinge the attached molecules (36) which may result in surface enhanced Raman scattered light received by a detector or a light spectrometer (17). Wavelength signatures may then be obtained from the spectrometer. The signatures may provide information about the molecules (36).
Abstract:
The electronic system (10) includes an electronic device (12) and a liquid holding section (14) that is thermally coupled to the electronic device. The electronic system further includes an impermeable section (16) that engages the liquid holding section. The impermeable section includes a channel (18) and a plurality of passages (20) that provide fluid communication between the liquid holding section and the channel. The electronic system further includes (i) a first fluid (22) that flows through the channel in the impermeable section to facilitate heat transfer from the electronic device to the first fluid; and (ii) a second fluid (24) that flows from the liquid holding section through the plurality of passages into the channel when the second fluid boils within the liquid holding section due to heat transfer from the electronic device to the second fluid. In some embodiments, the first and second fluids are different types of substances.
Abstract:
The present invention relates to an apparatus for testing multiple sample compounds for their biological effect comprising a porous block (1) having substantially planar top (3) and bottom surfaces (5) . The top surface (3) comprises a plurality of cell adhesive regions (7) and cell dis- adhesive regions (9) and the bottom surface (5) provides multiple sites (11) to load the sample compounds. These sites are located opposite from the cell adhesive regions on the top surface of the porous block. In certain embodiments, the invention further comprises at least one dissolvable layer (13) which provides multiple sites to load the sample compounds .
Abstract:
The invention is a method and apparatus capable of detecting constituents of a gas at extremely low concentrations comprising providing a medium that is absorbent of at least a first particular gas under a first environmental condition and desorbent of the particular gas under a second environmental condition, exposing the medium to a sample gas for a first period of time under the first environmental condition, during a second period of time after the first period of time, exposing the medium to the second environmental condition to cause the medium to desorb gas into an optical cavity of a cavity ring down spectrometer and introducing electromagnetic radiation into the cavity, during a third period of time after the second period of time, ceasing introduction of the electromagnetic radiation into the cavity and detecting the decay of the electromagnetic radiation in the cavity, and analyzing the decay of the light in the cavity to obtain a spectral analysis of the sample gas.
Abstract:
The present invention relates to the use of internally-generated hydrogen sulfide as a calibration gas for hydrogen sulfide sensors. The present invention also relates to an apparatus and methods for self-calibration of hydrogen sulfide sensors.
Abstract:
Disclosed is a compound that fluoresces in the presence of saccharides, the compound having the formula wherein F designates a fluorophore, R is a lower aliphatic or aromatic group, n and m are each O, 1, or 2, n+m is the integer 2 or 3, p is an integer of 1 to about 30, and the moieties [CH 2 CH 2 ] p and the benzene ring attached to the boron atom are substituted or unsubstituted. The present invention also provides a fully- integrated microfluidic system for detection of the fluorescence which comprises a light source; a self-assembled monolayer of a compound of the above formula coated on a gold surface that fluoresces in the presence of a saccharide; a light processor; and a detector.
Abstract translation:公开了在糖存在下发荧光的化合物,具有下式的化合物:其中F表示荧光团,R为低级脂族或芳族基团,n和m各自为0,1或2,n + m为整数 2或3的情况下,p为1至约30的整数,并且部分[CH 2 SUBCH 2 SUB 1] P 2和苯环连接 到硼原子被取代或未被取代。 本发明还提供了用于检测荧光的完全集成的微流体系统,其包括光源; 上式化合物的自组装单层,其涂布在金表面上,该金表面在糖存在下发荧光; 光处理器; 和一个探测器。
Abstract:
A nano shower cools a chip when a coolant sprays onto the chip package from an array of electro spray nozzles. Ideally, the coolant is not conductive and otherwise not harmful to electronics. As such, perfluorocarbons are ideal coolants. Distilled water also works in certain applications. A voltage difference between the coolant and chip package causes the coolant to spray from the electro spray nozzles onto the chip package. The coolant cools the chip package by evaporating or by absorbing heat and flowing away.