HIGH RESOLUTION METHODS AND PRECIPITATING REAGENTS FOR ISOLATING PROTEINS FROM PROTEINACEOUS MATERIAL
    1.
    发明申请
    HIGH RESOLUTION METHODS AND PRECIPITATING REAGENTS FOR ISOLATING PROTEINS FROM PROTEINACEOUS MATERIAL 审中-公开
    用于从蛋白质材料中分离蛋白质的高分辨率方法和预处理试剂

    公开(公告)号:WO2006107982A2

    公开(公告)日:2006-10-12

    申请号:PCT/US2006012524

    申请日:2006-04-05

    Inventor: MAURER GERALD L

    CPC classification number: C07K1/30

    Abstract: Novel high resolution methods and precipitating reagents for isolating desired protein populations from proteinaceous materials are disclosed. Uniquely, the methods and precipitating reagents of this invention are suitable for selectively and sequentially isolating consistently in high yields desired protein populations from various proteinaceous materials based upon the physical and chemical characteristics inherent in, and/or peculiar to, the desired protein populations. In addition, desired protein populations isolated with the new and vastly improved methods and precipitating reagents of this invention are highly concentrated and substantially pure and biologically active. The precipitating reagents basically are an alkali metal salt of a polyfunctional organic acid, exemplified by tri-potassium citrate monohydrate or tri-sodium citrate dihydrate, and a buffer for adjusting pH. Sources of proteinaceous materials may include, for example, animal or vegetable fluids and extracts.

    Abstract translation: 公开了用于从蛋白质材料中分离所需蛋白质群的新型高分辨率方法和沉淀试剂。 独特地,本发明的方法和沉淀试剂适合于基于所需蛋白质群体固有的和/或特有的物理和化学特性,从多种蛋白质材料中高产率地选择性和顺序地分离所需蛋白质群体。 此外,用本发明的新的和极大改进的方法和沉淀试剂分离的所需蛋白质群体是高度浓缩且基本上纯的和生物活性的。 沉淀试剂基本上是多官能有机酸的碱金属盐,例如三柠檬酸钾一水合物或三柠檬酸钠二水合物,以及用于调节pH的缓冲剂。 蛋白质材料的来源可以包括例如动物或植物液体和提取物。

    COMPOSITION FOR TREATING AND PREVENTING PERIODONTAL DISEASE AND METHOD OF USE
    2.
    发明申请
    COMPOSITION FOR TREATING AND PREVENTING PERIODONTAL DISEASE AND METHOD OF USE 审中-公开
    治疗和预防牙周病的组合物及使用方法

    公开(公告)号:WO2006081358A2

    公开(公告)日:2006-08-03

    申请号:PCT/US2006002788

    申请日:2006-01-26

    Inventor: MAURER GERALD L

    CPC classification number: A61Q11/00 A61K8/362 A61K8/737

    Abstract: The present invention is a mixture for treating and preventing periodontal disease comprising acemannan, an immuno-stimulant with tissue repair activity and a hydrated dialkali monometai polycarboxylate 1 : 1 molar ratio of metal-to-complexing agent, such that lysyl oxidase for collagen formation and subsequent tissue repair is activated.

    Abstract translation: 本发明是一种用于治疗和预防牙周病的混合物,所述混合物包含acemannan,具有组织修复活性的免疫刺激剂和金属与络合剂的1:1摩尔比的水合二碱基单甲基聚羧酸盐,用于胶原形成的赖氨酰氧化酶和 随后的组织修复被激活。

    METHODS FOR MAKING AND USING SYNERGISTIC MULTIFUNCTIONAL COMPOSITIONS
    3.
    发明申请
    METHODS FOR MAKING AND USING SYNERGISTIC MULTIFUNCTIONAL COMPOSITIONS 审中-公开
    制备和使用协同多功能组合物的方法

    公开(公告)号:WO2006047556A3

    公开(公告)日:2006-12-28

    申请号:PCT/US2005038480

    申请日:2005-10-25

    Inventor: MAURER GERALD L

    CPC classification number: A61K31/30 A61K31/315 A61K2300/00

    Abstract: The present invention is a synergistic palliative and/or therapeutic admixture for treating and/or medicating affected biological tissue in mammals. The admixture includes two or more multivalent metals and at least one polyfunctional organic ligand. The ligand is in the form of an alkaline earth salt. The molar ratio of metal to ligand is 1:1.

    Abstract translation: 本发明是用于治疗和/或治疗哺乳动物中受影响的生物组织的协同性姑息和/或治疗剂。 该混合物包括两种或更多种多价金属和至少一种多官能有机配体。 配体是碱土金属盐的形式。 金属与配体的摩尔比为1:1。

    OSTOMY DEVICE WITH DEODORIZING EFFICACY
    5.
    发明申请
    OSTOMY DEVICE WITH DEODORIZING EFFICACY 审中-公开
    具有降低效率的OSTOMY设备

    公开(公告)号:WO2007028062A3

    公开(公告)日:2007-10-11

    申请号:PCT/US2006034300

    申请日:2006-09-01

    Inventor: MAURER GERALD L

    CPC classification number: A61F5/441 A61F5/445

    Abstract: A method of reducing odor from ostomy devices by using a hydrated dialkali monometal polycarboxylate 1 :1 molar ratio of metal-to-complexing agent suspended in a carrier. As the ostomy device is filled with waste products, the hydrated dialkali monometal polycarboxylate 1 : 1 molar ratio of metal-to-complexing agent oxidizes the molecules of the waste products and neutralizes odor-causing molecules, and thereby reduces associated odors.

    Abstract translation: 通过使用悬浮在载体中的水合二元羧酸单羧酸盐1:1摩尔比的金属对络合剂来减少造口术装置的气味的方法。 当造口术装置充满废物时,金属 - 络合剂摩尔比1:1的水合二元羧酸单羧酸盐氧化废物分子并中和产生气味的分子,从而减少相关的气味。

    OSTOMY DEVICE WITH DEODORIZING EFFICACY

    公开(公告)号:CA2620768A1

    公开(公告)日:2007-03-08

    申请号:CA2620768

    申请日:2006-09-01

    Inventor: MAURER GERALD L

    Abstract: A method of reducing odor from ostomy devices by using a hydrated dialkali monometal polycarboxylate 1 :1 molar ratio of metal-to-complexing agent suspended in a carrier. As the ostomy device is filled with waste products, the hydrated dialkali monometal polycarboxylate 1 : 1 molar ratio of metal-t o- complexing agent oxidizes the molecules of the waste products and neutralize s odor-causing molecules, and thereby reduces associated odors.

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