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公开(公告)号：JP2011235106A
公开(公告)日：2011-11-24
申请号：JP2011106734
申请日：2011-05-11
Applicant: Sofradim Production Sa , Tyco Healthcare Group Lp , ソフラディム プロダクション ソシエテ アノニム , タイコ ヘルスケア グループ リミテッド パートナーシップ
Inventor： SARGEANT TIMOTHY , STOPEK JOSHUA , LADET SEBASTIEN , GRAVAGNA PHILIPPE , ELACHCHABI AMIN
CPC classification number: A61L27/50
Abstract: PROBLEM TO BE SOLVED: To prepare a surgical implant that is porous and matched to an issue structure and delivered in a manner with minimum invasiveness in accordance with its prescription.SOLUTION: The atomizable surgical implant includes: a first component including microparticulates having a size of about 10 μm to about 500 μm; and a second component including at least one cross-linking reagent. The second component includes the microparticulates whose surface is modified with at least one of the cross-linking reagent.
Abstract translation: 要解决的问题：准备多孔的外科植入物，并与发病结构匹配，并按照其处方以最小的侵入性递送。 解决方案：可雾化手术植入物包括：第一组分，其包含具有约10μm至约500μm尺寸的微粒; 和包含至少一种交联试剂的第二组分。 第二组分包括其表面用至少一种交联剂修饰的微粒。 版权所有（C）2012，JPO＆INPIT
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公开(公告)号：WO2012001532A2
公开(公告)日：2012-01-05
申请号：PCT/IB2011002260
申请日：2011-06-30
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: A61L15/22
Abstract: A medical device includes a substrate having at least a portion thereof functionalized with at least one reactive member and a chemotactic agent functionalized with at least one complementary reactive member, wherein the at least one reactive member and the at least one complementary reactive member are covalently bonded, adhering the chemotactic agent to the substrate.
Abstract translation: 医疗装置包括基底，所述基底的至少一部分用至少一个反应性部件和用至少一个互补反应性部件官能化的趋化剂官能化，其中所述至少一个反应性部件和所述至少一个互补反应性部件共价键合 将趋化剂粘附到基底上。
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公开(公告)号：WO2010070458A3
公开(公告)日：2010-11-25
申请号：PCT/IB2009008005
申请日：2009-12-18
Applicant: SOFRADIM PRODUCTION , CENTRE NAT RECH SCIENT , UNIV CLAUDE BERNARD LYON , SERRERO AURELIE , DOMARD ALAIN , DAVID LAURENT , TROMBOTTO STEPHANE , MONTANARI SUZELEI , BAYON YVES , GRAVAGNA PHILIPPE
Inventor： SERRERO AURELIE , DOMARD ALAIN , DAVID LAURENT , TROMBOTTO STEPHANE , MONTANARI SUZELEI , BAYON YVES , GRAVAGNA PHILIPPE
IPC: A61L24/08
Abstract: A biocompatible and bioresorbable adhesive for surgical and therapeutic uses is composed of a chitosan bonded with a functionalized polysaccharide.
Abstract translation: 用于手术和治疗用途的生物相容性和生物可吸收性粘合剂由与官能化多糖键合的壳聚糖组成。
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公开(公告)号：WO2009010879A3
公开(公告)日：2010-02-25
申请号：PCT/IB2008002695
申请日：2008-06-26
Applicant: SOFRADIM PRODUCTION , LEFRANC OLIVIER , GRAVAGNA PHILIPPE , THERIN MICHEL , BAYON YVES
Inventor： LEFRANC OLIVIER , GRAVAGNA PHILIPPE , THERIN MICHEL , BAYON YVES
CPC classification number: A61F2/0063 , A61F2/0045 , A61L27/34 , A61L27/54 , A61L27/56 , A61L31/10 , A61L31/146 , A61L31/16 , A61L2300/606 , C08L89/06
Abstract: A mesh implant is disclosed which may be utilized for treating urinary incontinence, hernias, uterovaginal prolapses and other related injuries.
Abstract translation: 公开了可用于治疗尿失禁，疝气，子宫阴道脱垂和其他相关损伤的网状植入物。
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5.发明申请
公开(公告)号：WO2010052583A3
公开(公告)日：2010-11-04
申请号：PCT/IB2009007661
申请日：2009-11-06
Applicant: SOFRADIM PRODUCTION , BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
Inventor： BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
CPC classification number: A61L27/20 , A61F13/00012 , A61F13/00021 , A61F13/00059 , A61F2013/00153 , A61F2013/00255 , A61F2013/00314 , A61K9/70 , A61L27/50 , A61L27/56 , A61L27/58 , Y10T428/24479
Abstract: The present invention relates to an implant comprising: a sheet of bacterial cellulose having a macro-pattern positioned on at least a portion thereof. The invention also relates to a method for making such an implant.
Abstract translation: 本发明涉及一种植入物，其包含：细菌纤维素片，其至少一部分上具有宏观图案。 本发明还涉及制造这种植入物的方法。
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Patent Agency Ranking6.发明申请APPARATUS AND METHOD OF REACTING POLYMERS PASSING THROUGH METAL ION CHELATED RESIN MATRIX TO PRODUCE INJECTABLE MEDICAL DEVICES 审中-公开通过金属离子螯合树脂基质反应聚合物以生产可注射医疗器械的装置和方法
公开(公告)号：WO2010095047A3
公开(公告)日：2010-10-14
申请号：PCT/IB2010000576
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: B01J14/00 , A61B17/00 , A61M5/19 , B01F5/06 , B01F13/00 , B01F15/00 , B01J19/00 , B01J23/72 , B01J35/04
CPC classification number: B01J19/18 , A61B17/00491 , A61B2017/00495 , B01F5/0615 , B01F5/0683 , B01F5/0688 , B01F13/002 , B01F13/0023 , B01J14/005 , B01J19/0053 , B01J19/0066 , B01J23/72 , B01J35/04 , B01J2219/00761 , C08G63/66
Abstract: The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective dispense a first precursor and a second precursor, a mixing assembly configured to mix the first and second precursors, and at least one catalyzing element including a transition metal ion to aid in the polymerization of the first and second precursors. The process includes dispensing a volume of the first precursor and a volume of the second precursor into a mixing assembly and mixing the first and second precursors. The first and second precursors each possess a core and at least one functional group known to have click reactivity with each other. The mixed precursors are contacted with a transition metal catalyst to produce a flowable composition for use as a medical device.
Abstract translation: 本公开涉及用于由可注射组合物形成医疗装置的设备和方法。 该装置包括：供应组件，其被配置为保持和选择性地分配第一前体和第二前体;混合组件，其被配置为混合第一和第二前体;以及至少一个催化元件，其包括过渡金属离子以帮助 第一和第二前体。 该方法包括将一定体积的第一前体和一定体积的第二前体分配到混合组件中并混合第一和第二前体。 第一和第二前体各自具有核心和至少一个已知具有彼此点击反应性的官能团。 混合前体与过渡金属催化剂接触以产生用作医疗装置的可流动组合物。
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公开(公告)号：WO2009031047A3
公开(公告)日：2010-04-22
申请号：PCT/IB2008003107
申请日：2008-09-05
Applicant: SOFRADIM PRODUCTION , GRAVAGNA PHILIPPE , BAYON YVES , LADET SEBASTIEN
Inventor： GRAVAGNA PHILIPPE , BAYON YVES , LADET SEBASTIEN
Abstract: A bioresorbable and biocompatible compound for surgical use is composed of functionalized collagen cross-linked with a glycosaminoglycan.
Abstract translation: 用于手术使用的生物可再吸收和生物相容性化合物由与糖胺聚糖交联的官能化胶原组成。
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公开(公告)号：WO2010095058A3
公开(公告)日：2011-05-05
申请号：PCT/IB2010000703
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
CPC classification number: A61L31/10 , A61L17/005 , A61L17/145 , A61L31/16 , A61L2300/252 , A61L2300/256 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/43 , A61L2300/606 , A61L2400/18 , A61L2420/02
Abstract: The present disclosure relates to implantable non-bioabsorbable medical devices having an amphiphilic coating for reducing the inflammatory response to the device after implantation and methods of making such devices.
Abstract translation: 本公开涉及具有两亲性涂层的可植入非生物可吸收的医疗器械，用于在植入后减少对器件的炎症反应以及制造这些器件的方法。
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公开(公告)号：WO2010095052A3
公开(公告)日：2010-12-29
申请号：PCT/IB2010000630
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: A61L27/48
CPC classification number: A61K47/4823 , A61K47/30 , A61K47/48038 , A61K47/48092 , A61K47/48238 , A61K47/542 , A61K47/549 , A61K47/61 , A61K47/62 , A61L27/26 , A61L27/48 , A61L27/50 , A61L27/54 , A61L31/14 , A61L31/16 , A61L2300/00 , C08L101/02
Abstract: The present disclosure relates to compounds and medical devices activated with a solvophobic material functionalized with a first reactive member and methods of making such compounds and devices.
Abstract translation: 本公开涉及通过用第一反应性成员官能化的溶剂疏油物质活化的化合物和医疗装置以及制备这种化合物和装置的方法。
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公开(公告)号：WO2010095044A3
公开(公告)日：2010-11-04
申请号：PCT/IB2010000571
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: A61L31/10 , C08J7/04 , C08L101/16 , C09D105/08
CPC classification number: A61L17/145 , A61L17/06 , C08J7/047 , C09D105/08
Abstract: The present disclosure relates to implantable bioabsorbable medical devices having an amphiphilic coating for delaying the degradation of the device and methods of making such devices.
Abstract translation: 本公开涉及具有用于延迟装置劣化的两亲涂层的可植入生物可吸收的医疗装置及其制造方法。
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