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公开(公告)号：JP2011235106A
公开(公告)日：2011-11-24
申请号：JP2011106734
申请日：2011-05-11
Applicant: Sofradim Production Sa , Tyco Healthcare Group Lp , ソフラディム プロダクション ソシエテ アノニム , タイコ ヘルスケア グループ リミテッド パートナーシップ
Inventor： SARGEANT TIMOTHY , STOPEK JOSHUA , LADET SEBASTIEN , GRAVAGNA PHILIPPE , ELACHCHABI AMIN
CPC classification number: A61L27/50
Abstract: PROBLEM TO BE SOLVED: To prepare a surgical implant that is porous and matched to an issue structure and delivered in a manner with minimum invasiveness in accordance with its prescription.SOLUTION: The atomizable surgical implant includes: a first component including microparticulates having a size of about 10 μm to about 500 μm; and a second component including at least one cross-linking reagent. The second component includes the microparticulates whose surface is modified with at least one of the cross-linking reagent.
Abstract translation: 要解决的问题：准备多孔的外科植入物，并与发病结构匹配，并按照其处方以最小的侵入性递送。 解决方案：可雾化手术植入物包括：第一组分，其包含具有约10μm至约500μm尺寸的微粒; 和包含至少一种交联试剂的第二组分。 第二组分包括其表面用至少一种交联剂修饰的微粒。 版权所有（C）2012，JPO＆INPIT
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公开(公告)号：WO2012001532A2
公开(公告)日：2012-01-05
申请号：PCT/IB2011002260
申请日：2011-06-30
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: A61L15/22
Abstract: A medical device includes a substrate having at least a portion thereof functionalized with at least one reactive member and a chemotactic agent functionalized with at least one complementary reactive member, wherein the at least one reactive member and the at least one complementary reactive member are covalently bonded, adhering the chemotactic agent to the substrate.
Abstract translation: 医疗装置包括基底，所述基底的至少一部分用至少一个反应性部件和用至少一个互补反应性部件官能化的趋化剂官能化，其中所述至少一个反应性部件和所述至少一个互补反应性部件共价键合 将趋化剂粘附到基底上。
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公开(公告)号：WO2010095056A2
公开(公告)日：2010-08-26
申请号：PCT/IB2010000665
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , TYCO HEALTHCARE , HADBA AHMAD ROBERT , LADET SEBASTIEN
Inventor： HADBA AHMAD ROBERT , LADET SEBASTIEN
CPC classification number: A61L31/10 , A61L17/145 , A61L29/085 , A61L31/16 , A61L2300/606 , A61L2420/02 , B05D1/00 , C08J7/047 , C08L101/02
Abstract: Implantable medical devices include a substrate having applied thereto a coating including a polymeric material possessing a core and at least one functional group known to have click reactivity.
Abstract translation: 可植入的医疗装置包括具有涂覆有涂层的基材，所述涂层包含具有核和至少一个已知具有点击反应性的官能团的聚合物材料。
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公开(公告)号：WO2011117744A3
公开(公告)日：2012-01-19
申请号：PCT/IB2011001116
申请日：2011-03-24
Applicant: SOFRADIM PRODUCTION , TYCO HEALTHCARE , HADBA AHMAD ROBERT , LADET SEBASTIEN , KENNEDY JACK
Inventor： HADBA AHMAD ROBERT , LADET SEBASTIEN , KENNEDY JACK
IPC: A61L29/14
CPC classification number: A61B17/00491 , A61B17/0218 , A61B17/3421 , A61B17/3423 , A61B2017/00495 , A61B2017/00884 , A61B2017/3419 , A61F2/0063 , A61F2002/0072 , A61L29/14
Abstract: A surgical access device for use in minimally invasive surgery is provided which includes a plurality of reactive members of a specific binding pair releasably contained on a surface of the access device, the reactive members having an affinity for binding a cellular component of tissue cells and another affinity for binding complementary members of the specific binding pair. A kit comprising such a surgical access device is also provided.
Abstract translation: 提供了一种用于微创手术的手术进入装置，其包括可释放地包含在进入装置的表面上的特异性结合对的多个反应性构件，所述反应性构件具有结合组织细胞的细胞组分和另一种的亲和力 对特异性结合对的互补成员的结合的亲合力。 还提供了包括这种外科进入装置的套件。
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5.发明申请
公开(公告)号：WO2010052583A3
公开(公告)日：2010-11-04
申请号：PCT/IB2009007661
申请日：2009-11-06
Applicant: SOFRADIM PRODUCTION , BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
Inventor： BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
CPC classification number: A61L27/20 , A61F13/00012 , A61F13/00021 , A61F13/00059 , A61F2013/00153 , A61F2013/00255 , A61F2013/00314 , A61K9/70 , A61L27/50 , A61L27/56 , A61L27/58 , Y10T428/24479
Abstract: The present invention relates to an implant comprising: a sheet of bacterial cellulose having a macro-pattern positioned on at least a portion thereof. The invention also relates to a method for making such an implant.
Abstract translation: 本发明涉及一种植入物，其包含：细菌纤维素片，其至少一部分上具有宏观图案。 本发明还涉及制造这种植入物的方法。
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Patent Agency Ranking6.发明申请APPARATUS AND METHOD OF REACTING POLYMERS PASSING THROUGH METAL ION CHELATED RESIN MATRIX TO PRODUCE INJECTABLE MEDICAL DEVICES 审中-公开通过金属离子螯合树脂基质反应聚合物以生产可注射医疗器械的装置和方法
公开(公告)号：WO2010095047A3
公开(公告)日：2010-10-14
申请号：PCT/IB2010000576
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
IPC: B01J14/00 , A61B17/00 , A61M5/19 , B01F5/06 , B01F13/00 , B01F15/00 , B01J19/00 , B01J23/72 , B01J35/04
CPC classification number: B01J19/18 , A61B17/00491 , A61B2017/00495 , B01F5/0615 , B01F5/0683 , B01F5/0688 , B01F13/002 , B01F13/0023 , B01J14/005 , B01J19/0053 , B01J19/0066 , B01J23/72 , B01J35/04 , B01J2219/00761 , C08G63/66
Abstract: The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective dispense a first precursor and a second precursor, a mixing assembly configured to mix the first and second precursors, and at least one catalyzing element including a transition metal ion to aid in the polymerization of the first and second precursors. The process includes dispensing a volume of the first precursor and a volume of the second precursor into a mixing assembly and mixing the first and second precursors. The first and second precursors each possess a core and at least one functional group known to have click reactivity with each other. The mixed precursors are contacted with a transition metal catalyst to produce a flowable composition for use as a medical device.
Abstract translation: 本公开涉及用于由可注射组合物形成医疗装置的设备和方法。 该装置包括：供应组件，其被配置为保持和选择性地分配第一前体和第二前体;混合组件，其被配置为混合第一和第二前体;以及至少一个催化元件，其包括过渡金属离子以帮助 第一和第二前体。 该方法包括将一定体积的第一前体和一定体积的第二前体分配到混合组件中并混合第一和第二前体。 第一和第二前体各自具有核心和至少一个已知具有彼此点击反应性的官能团。 混合前体与过渡金属催化剂接触以产生用作医疗装置的可流动组合物。
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公开(公告)号：WO2009031047A3
公开(公告)日：2010-04-22
申请号：PCT/IB2008003107
申请日：2008-09-05
Applicant: SOFRADIM PRODUCTION , GRAVAGNA PHILIPPE , BAYON YVES , LADET SEBASTIEN
Inventor： GRAVAGNA PHILIPPE , BAYON YVES , LADET SEBASTIEN
Abstract: A bioresorbable and biocompatible compound for surgical use is composed of functionalized collagen cross-linked with a glycosaminoglycan.
Abstract translation: 用于手术使用的生物可再吸收和生物相容性化合物由与糖胺聚糖交联的官能化胶原组成。
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公开(公告)号：WO2010095046A3
公开(公告)日：2010-12-16
申请号：PCT/IB2010000575
申请日：2010-02-22
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , GRAVAGNA PHILIPPE
Inventor： LADET SEBASTIEN , GRAVAGNA PHILIPPE
CPC classification number: A61B17/00491 , A61L15/22 , A61L15/58 , A61L31/04 , A61L31/14 , Y10T156/10
Abstract: The invention relates to a kit comprising: - a polymeric medical device having a plurality of reactive members of a specific binding pair attached to a surface of the device; and a container containing a mixture including complementary reactive members of the specific binding pair, the complementary reactive members having a functionality adapted to adhere them to biological tissue upon contact.
Abstract translation: 本发明涉及一种试剂盒，其包括： - 聚合物医疗装置，其具有连接到装置的表面的特定结合对的多个反应性构件; 和含有包含特异性结合对的互补反应性成员的混合物的容器，所述互补反应性成员具有适于在接触时将其粘附到生物组织上的功能。
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公开(公告)号：WO2010043980A3
公开(公告)日：2010-11-25
申请号：PCT/IB2009007520
申请日：2009-10-16
Applicant: SOFRADIM PRODUCTION , LADET SEBASTIEN , BAYON YVES
Inventor： LADET SEBASTIEN , BAYON YVES
Abstract: Multi-layer structures are useful as surgical patches.
Abstract translation: 多层结构可用作手术贴片。
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10.发明申请MEDICAL IMPLANT INCLUDING A 3D MESH OF OXIDIZED CELLULOSE AND A COLLAGEN SPONGE 审中-公开医用植入物，包括氧化纤维素和胶原海绵的三维网
公开(公告)号：WO2010052587A3
公开(公告)日：2010-11-04
申请号：PCT/IB2009007742
申请日：2009-11-06
Applicant: SOFRADIM PRODUCTION , BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
Inventor： BAYON YVES , LADET SEBASTIEN , LEFRANC OLIVIER , GRAVAGNA PHILIPPE
Abstract: The present invention relates to A bioresorbable implant comprising: a bioresorbable porous layer including a biopolymer foam and defining first pores, a bioresorbable porous three-dimensional mesh made from a microbial cellulose and defining second pores, wherein the bioresorbable porous layer is disposed in the bioresorbable porous three-dimensional mesh. The invention also relates to a method of making a bioresorbable implant.
Abstract translation: 本发明涉及一种生物再吸收植入物，其包括：生物可再吸收的多孔层，包括生物聚合物泡沫并限定第一孔，由微生物纤维素制成并限定第二孔的生物可再吸收的多孔三维网，其中所述生物可再吸收的多孔层设置在生物可再吸收的 多孔三维网。 本发明还涉及制造生物可吸收植入物的方法。
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