Antioxidant-infused ultra high molecular weight polyethylene

    公开(公告)号:US10265891B2

    公开(公告)日:2019-04-23

    申请号:US14957790

    申请日:2015-12-03

    Applicant: Zimmer, Inc.

    Inventor: Dirk Pletcher

    Abstract: Various embodiments disclosed relate to antioxidant-stabilized materials including ultra high molecular weight polyethylene (UHMWPE), methods of making the same, and medical implants including the same. In various embodiments, the present invention provides a method of adding antioxidant to UHMWPE. The method includes obtaining or providing a porous solid material including UHMWPE. The method includes coating the porous solid material with a liquid composition including at least one antioxidant such that at least some of the liquid composition enters void space of the porous solid material, to provide an antioxidant-infused solid material. The method also includes melt-consolidating the antioxidant-infused solid material, to provide a melt-consolidated material.

    Melt-stabilized ultra high molecular weight polyethylene and method of making the same

    公开(公告)号:US10184031B2

    公开(公告)日:2019-01-22

    申请号:US15124454

    申请日:2015-02-26

    Applicant: Zimmer, Inc.

    Inventor: Dirk Pletcher

    Abstract: Various embodiments disclosed relate to melt-stabilized materials including ultra high molecular weight polyethylene (UHMWPE), methods of making the same, and medical implants including the same. In various embodiments, the present invention provides a method of melt-stabilizing a material including UHMWPE. The method includes obtaining or providing a solid material including UHMWPE including a first concentration of free-radicals. The method includes coating at least part of the solid material with a liquid composition including at least one antioxidant, to provide a coated solid material. The method includes heating the coated solid material in an environment including oxygen, the heating being sufficient to melt at least part of the UHMWPE, to provide a heated material. The method also includes solidifying the heated material, to provide a melt-stabilized material including UHMWPE including a second concentration of free-radicals, wherein the second concentration of free-radicals is less than the first concentration of free-radicals.

    MELT-STABILIZED ULTRA HIGH MOLECULAR WEIGHT ANTIOXIDANT
    8.
    发明申请
    MELT-STABILIZED ULTRA HIGH MOLECULAR WEIGHT ANTIOXIDANT 审中-公开
    耐磨稳定超高分子量抗氧化剂

    公开(公告)号:US20160280863A1

    公开(公告)日:2016-09-29

    申请号:US15073042

    申请日:2016-03-17

    Applicant: Zimmer, Inc.

    Inventor: Dirk Pletcher

    Abstract: Various embodiments disclosed relate to melt-stabilized ultra high molecular weight antioxidant, methods of making the same, and medical implants made from the same. In various embodiments, the present invention provides a method of melt-stabilizing ultra high molecular weight polyethylene (UHMWPE). The method can include coating a solid material including LIMA/PE with an antioxidant, to provide an antioxidant-coated solid material. The method can include pre-irradiatively heating the antioxidant-coated solid material to diffuse the antioxidant therein, to provide an antioxidant-diffused solid material. The method can include irradiating the antioxidant-diffused solid material, to provide an irradiated solid material. The method can include post-irradiatively heating the irradiated solid material, the heating sufficient to melt at least part of the UHMWPE, to provide a heated material. The method can also include solidifying the heated material, to provide a melt-stabilized material.

    Abstract translation: 所公开的各种实施方案涉及熔融稳定的超高分子量抗氧化剂,其制备方法和由其制备的医用植入物。 在各种实施方案中,本发明提供了一种熔融稳定超高分子量聚乙烯(UHMWPE)的方法。 该方法可以包括用抗氧化剂涂覆包括LIMA / PE的固体材料,以提供抗氧化剂涂覆的固体材料。 该方法可以包括预先加热抗氧化剂涂覆的固体材料以使其中的抗氧化剂扩散,以提供抗氧化剂扩散的固体材料。 该方法可以包括照射抗氧化剂扩散的固体材料,以提供照射的固体材料。 该方法可以包括对辐射的固体材料进行后照射加热,足以熔化至少部分UHMWPE的加热,以提供加热的材料。 该方法还可以包括固化加热的材料,以提供熔融稳定的材料。

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