公开(公告)号：US10759899B2

公开(公告)日：2020-09-01

申请号：US16053225

申请日：2018-08-02

Applicant: Colorado State University Research Foundation

Inventor： Eugene Y. Chen ,  Jian-Bo Zhu

IPC: C08G63/08 ,  C08G63/82 ,  C08J11/12

Abstract: The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.

公开(公告)号：US20190040191A1

公开(公告)日：2019-02-07

申请号：US16053225

申请日：2018-08-02

Applicant: Colorado State University Research Foundation

Inventor： Eugene Y. CHEN ,  Jian-Bo Zhu

IPC: C08G63/08 ,  C08G63/82 ,  C08J11/12

Abstract: The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.

公开(公告)号：US10174161B2

公开(公告)日：2019-01-08

申请号：US15756670

申请日：2016-09-02

Applicant: Colorado State University Research Foundation

Inventor： Eugene Y. Chen ,  Jian-Bo Zhu

IPC: C08G63/82 ,  C08G63/08 ,  C07D405/04 ,  C07D515/08 ,  C08L67/04

Abstract: B/N Lewis pairs have been discovered to catalyze rapid epimerization of meso-lactide (LA) or LA diastereomers quantitatively into rac-LA. The obtained rac-LA can be kinetically polymerized into poly(L-lactide) and optically resolved D-LA, with a high stereoselectivity factor kL/kD of 53 and an ee value of 91% at 50.6% monomer conversion, by a bifunctional chiral catalyst. The epimerization and enantioselective polymerization can be coupled into a one-pot process for transforming meso-LA directly into poly(L-lactide) and D-LA.