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公开(公告)号：US11638737B2
公开(公告)日：2023-05-02
申请号：US17023447
申请日：2020-09-17
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyoung Ja Kim , Chang Bae Jin , Hyun Beom Lee , Hyun Soo Choi , You Bin Cho
Abstract: Disclosed are a Filipendula glaberrima alcoholic extract and solvent fractions fractionated therefrom or novel compounds 1 and 2 purely isolated from a Filipendula glaberrima ethyl acetate fraction that have an excellent inhibitory effect against HMG-CoA reductase activity, an excellent antioxidant effect and a remarkably excellent effect of suppressing the formation of foam cells in macrophages. Also, disclosed is a pharmaceutical composition or health food composition for treating, preventing and ameliorating vascular diseases, hypercholesterolemia, or heart diseases caused by hypercholesterolemia, or lowering blood cholesterol levels, containing, as active ingredients, the Filipendula glaberrima alcoholic extract and the solvent fractions or the novel compounds 1 and 2.
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公开(公告)号：US11631878B2
公开(公告)日：2023-04-18
申请号：US17212261
申请日：2021-03-25
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Ho Il Ji , Jong Ho Lee , Byung Kook Kim , Ji Won Son , Kyung Joong Yoon , Hyoung Chul Kim , Sang Baek Park , Sung Eun Yang , Jun Seok Kim
IPC: H01M8/1253 , H01M4/90 , H01M4/88 , H01M4/86 , H01M8/12
Abstract: Disclosed is a method of manufacturing a solid oxide fuel cell including a multi-layered electrolyte layer using a calendering process. The method for manufacturing a solid oxide fuel cell is a continuous process, thus providing high productivity and maximizing facility investment and processing costs. In addition, the solid oxide fuel cell manufactured by the method includes an anode that is free of interfacial defects and has a uniform packing structure, thereby advantageously greatly improving the production yield and power density. In addition, the solid oxide fuel cell has excellent interfacial bonding strength between respective layers included therein, and includes a multi-layered electrolyte layer in which the secondary phase at the interface is suppressed and which has increased density, thereby advantageously providing excellent output characteristics and long-term stability even at an intermediate operating temperature.
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公开(公告)号：US20230114565A1
公开(公告)日：2023-04-13
申请号：US17962026
申请日：2022-10-07
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Inventor： Hak Cheol KWON , Jaeyoung KWON , Seong-Hwan KIM , Jin Wook CHA , Soon Kwang LEE , Won Kyu KIM , Yujin KWON , Suyeon CHO , Taek Joo LEE , Jung Hwa KANG , Wan Hee LEE , Hyunki KIM
IPC: A61K36/73 , A61K36/268 , A61P35/00 , A61P1/00
Abstract: Provided are compositions for preventing or treating cancer, the compositions including Rubus longisepalus var. tozawai (Nakai) T.B.Lee extracts, or a fraction thereof as an active ingredient.
According to an aspect, a Rubus longisepalus var. tozawai (Nakai) T.B.Lee extract has an excellent anticancer efficacy against various cancers including diffuse-type gastric cancer, and thus, a cancer treatment agent having an excellent effect may be developed by using the extract as an active ingredient.-
公开(公告)号：US11618916B2
公开(公告)日：2023-04-04
申请号：US16568363
申请日：2019-09-12
Inventor： Ick Chan Kwon , Ju Hee Ryu , Young-Ji Ko , Hye-Sun Kim , Nam-Hyuk Cho , Eun-Jeong Yang , Jae Won Lee
IPC: C12Q1/37 , G01N33/573
Abstract: A probe for measuring the activity of caspase-1 according to the present disclosure can specifically image cells or tissues where inflammatory response is induced because it is cleaved by reacting specifically with the active caspase-1 enzyme in vivo and in vitro and re-emits fluorescence. The probe for measuring the activity of caspase-1 can be used for various purposes, such as for imaging of cells or tissues where inflammatory response is induced, as a drug carrier, for screening of a drug inhibiting inflammatory response, etc.
The probe for measuring the activity of caspase-1 is applicable both in vivo and in vitro, and can be used for various applications such as high-throughput screening for new drug development, early diagnosis of diseases, etc.-
公开(公告)号：US20230102450A1
公开(公告)日：2023-03-30
申请号：US17749888
申请日：2022-05-20
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Donghyun HWANG , Min Woo LEE
Abstract: The present disclosure relates to a sensor module for measuring a displacement occurring in a sensor by a confocal principle, a strain sensor device comprising the same, and a method for measuring a strain in a target using the same. Specifically, the sensor module according to an embodiment of the present disclosure includes a first single-mode optical fiber, a first GRIN optical fiber, a multi-mode optical fiber, a second GRIN optical fiber and a second single-mode optical fiber connected in an axial direction, wherein light inputted through the first single-mode optical fiber is transmitted to the second single-mode optical fiber through the series of optical fibers, and light forming a focal point in the core of the second single-mode optical fiber is detected using a confocal principle.
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Patent Agency Ranking
公开(公告)号：US20230093685A1
公开(公告)日：2023-03-23
申请号：US17849571
申请日：2022-06-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyun Ju OH , Youngsoon UM , Sun Mi LEE , Gyeongtaek GONG , Ja Kyong KO
Abstract: The present disclosure relates to a composition for preparing hexanol or butanol and a method for preparing hexanol or butanol using ethanol and synthesis gas, wherein the composition according to an aspect of the present disclosure is a medium composition containing ethanol as an active ingredient, and by culturing a strain producing hexanol or butanol after inoculating with a medium containing the composition and supplying synthesis gas, hexanol or butanol can be prepared economically using inexpensive synthesis gas, and hexanol or butanol can be prepared with high efficiency by focusing the flow of a carbon source consumed in a fermentation process to the production of hexanol or butanol.
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97.发明申请公开(公告)号：US20230066491A1
公开(公告)日：2023-03-02
申请号：US17893016
申请日：2022-08-22
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventor： In Soo KIM , Donghee Son , Hannah Kwon , Hye Jun Kim , Duhwan Seong , Jinhyun Kim
IPC: H01L25/16
Abstract: Provided is a device assembly including a substrate for mounting a device thereon, electrodes provided on the substrate to be electrically connected to the device, and an encapsulation provided on the substrate and the electrodes to accommodate and encapsulate the device therein, wherein the substrate and the encapsulation are made of a self-healing polymer (SHP), and wherein the electrodes are made of a conductive polymer composite including the SHP.
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公开(公告)号：US11594744B2
公开(公告)日：2023-02-28
申请号：US17348578
申请日：2021-06-15
Inventor： Jihui Seo , Jin Woo Choung , Pyung Soon Kim , Suk Woo Nam , Hyangsoo Jeong , Yongmin Kim , Jaewon Kirk , Chang Won Yoon
IPC: H01M8/0612 , B01J19/24 , H01M8/065 , C01B3/00 , C01B3/06
Abstract: A hybrid dehydrogenation reaction system includes: an acid aqueous solution tank having an acid aqueous solution; an exothermic dehydrogenation reactor including a chemical hydride of a solid state and receiving the acid aqueous solution from the acid aqueous solution tank for an exothermic dehydrogenation reaction of the chemical hydride and the acid aqueous solution to generate hydrogen; an LOHC tank including a liquid organic hydrogen carrier (LOHC); and an endothermic dehydrogenation reactor receiving the liquid organic hydrogen carrier from the LOHC tank and generating hydrogen through an endothermic dehydrogenation reaction of the liquid organic hydrogen carrier by using heat generated from the exothermic dehydrogenation reactor.
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公开(公告)号：US20230057916A1
公开(公告)日：2023-02-23
申请号：US17724609
申请日：2022-04-20
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Ung LEE , Da Hye WON , Jai Hyun KOH , Dong Ki LEE , Hyung Suk OH , Byoung Koun MIN
IPC: C25B15/08 , B01D53/62 , B01D53/78 , B01D53/96 , C25B1/23 , C25B9/19 , C25B9/70 , C25B11/052 , C25B11/065 , C25B11/081 , H01M8/0656 , H01M8/0612 , B01J19/24 , C07C29/151
Abstract: A system of utilizing carbon dioxide comprises a carbon dioxide capturing device for capturing carbon dioxide, an electrochemical reaction device for producing synthetic gas by reducing the carbon dioxide captured by the carbon dioxide capturing device, a hydrogen carrier manufacturing device for manufacturing a hydrogen carrier material by using the synthetic gas produced by the electrochemical reaction device, a dehydrogenation device for producing hydrogen from the hydrogen carrier material manufactured by the hydrogen carrier manufacturing device, and a hydrogen utilization device for utilizing hydrogen produced by the dehydrogenation device, wherein the dehydrogenation device further produces carbon dioxide from the hydrogen carrier material and supplies the carbon dioxide to the carbon dioxide capturing device.
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100.发明授权公开(公告)号：US11580629B2
公开(公告)日：2023-02-14
申请号：US17013859
申请日：2020-09-08
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Ig Jae Kim , Heeseung Choi , Hyunki Lim , Yeji Choi
Abstract: Embodiments relate to a method and system for determining a situation of a facility by imaging a sensing data of the facility including receiving sensing data through a plurality of sensors at a query time, generating a situation image at the query time, showing the situation of the facility at the query time based on the sensing data, and determining if an abnormal situation occurred at the query time by applying the situation image to a pre-learned situation determination model.
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