公开(公告)号：US09848778B2

公开(公告)日：2017-12-26

申请号：US13844257

申请日：2013-03-15

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot ,  Linda L. Ruetz ,  Carl Schu

IPC: A61B5/0205 ,  A61B5/0452 ,  A61B5/0488 ,  A61B5/00 ,  A61B5/145 ,  B01D61/32 ,  B01D65/02 ,  A61B5/20 ,  B01D61/24 ,  A61M1/14 ,  A61B5/053 ,  A61M1/16 ,  A61M1/36

CPC classification number: A61B5/0205 ,  A61B5/0031 ,  A61B5/0452 ,  A61B5/0488 ,  A61B5/0537 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4836 ,  A61B5/6866 ,  A61B5/7275 ,  A61B2560/0223 ,  A61M1/14 ,  A61M1/1601 ,  A61M1/3609 ,  A61M2205/18 ,  A61M2205/3523 ,  A61M2205/52 ,  A61M2205/70 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/30 ,  B01D61/243 ,  B01D61/32 ,  B01D65/02 ,  B01D2321/12 ,  B01D2321/40 ,  G06F19/00

Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.

公开(公告)号：US09839360B2

公开(公告)日：2017-12-12

申请号：US13892166

申请日：2013-05-10

Applicant: BioMetric Holdings, Inc.

Inventor： Mihailo V. Rebec ,  Slavko N. Rebec ,  Richard G. Sass ,  Mihailo R. Rebec

IPC: A61M1/14 ,  A61B5/1455 ,  A61B5/00 ,  A61M1/16 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/20 ,  A61B5/103

CPC classification number: A61B5/0082 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/1032 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/201 ,  A61B2560/045 ,  A61M1/1601 ,  G06F19/00 ,  G16H40/63

Abstract: An end stage renal disease (ESRD) monitoring system may include an implantable sensor and a reader device with an optical sensor. The implantable sensor may be configured to detect a group of analytes relevant to ESRD, such as glucose, creatinine, urea, and potassium. The implantable sensor may be implanted into the dermis of an animal, and may exhibit color changes in response to the presence of the target analytes or reaction product(s) thereof. The reader device may be configured to capture an image of the implanted sensor and to determine the concentration of the target analytes based at least in part on the image. The reader device may be a personal electronic device such as a cell phone, PDA, or personal computer.

公开(公告)号：US20170347954A1

公开(公告)日：2017-12-07

申请号：US15506740

申请日：2015-08-28

Applicant: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.

Inventor： Carol SULLIVAN ,  Stefan TUNEV

IPC: A61B5/00 ,  A61B10/00 ,  A61B18/14 ,  A61N1/36 ,  G01N33/493 ,  G01N33/53 ,  A61B5/20 ,  G01N33/94 ,  A61N1/05 ,  A61B18/00

CPC classification number: A61B5/4848 ,  A61B5/04001 ,  A61B5/0538 ,  A61B5/14507 ,  A61B5/201 ,  A61B5/207 ,  A61B5/4035 ,  A61B5/4041 ,  A61B10/007 ,  A61B18/1492 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2218/002 ,  A61N1/0551 ,  A61N1/36117 ,  G01N33/493 ,  G01N33/5308 ,  G01N33/74 ,  G01N33/9433 ,  G01N2800/347 ,  G01N2800/52

Abstract: Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.

公开(公告)号：US20170332926A1

公开(公告)日：2017-11-23

申请号：US15663409

申请日：2017-07-28

Applicant: Ablative Solutions, Inc.

Inventor： David R. Fischell ,  Tim A. Fischell ,  Vartan Ghazarossian ,  Steven Almany ,  Michael Sasha John

IPC: A61B5/04 ,  A61B18/14 ,  A61B5/00 ,  A61B18/04 ,  A61B18/02 ,  A61B18/00 ,  A61M25/00 ,  A61B18/18 ,  A61B18/12 ,  A61B17/32 ,  A61B5/20 ,  A61B90/00 ,  A61B17/00

CPC classification number: A61B5/04001 ,  A61B5/201 ,  A61B5/4035 ,  A61B5/6848 ,  A61B5/6852 ,  A61B17/320068 ,  A61B18/0218 ,  A61B18/1233 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2017/00039 ,  A61B2018/00214 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00666 ,  A61B2018/00738 ,  A61B2018/00779 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/00916 ,  A61B2018/0212 ,  A61B2018/046 ,  A61B2018/048 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B2090/376 ,  A61B2090/3966 ,  A61M2025/0095

Abstract: An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media.

公开(公告)号：US20170311838A1

公开(公告)日：2017-11-02

申请号：US15652580

申请日：2017-07-18

Applicant: Gyrus Acmi, Inc. (d.b.a Olympus Surgical Technolog

Inventor： Tailin Fan

IPC: A61B5/05 ,  G01R33/00 ,  A61B5/06 ,  A61B5/00 ,  G01R33/09 ,  A61B17/34 ,  A61B34/20 ,  A61B90/00 ,  A61B5/20

CPC classification number: A61B5/05 ,  A61B5/062 ,  A61B5/201 ,  A61B5/6848 ,  A61B17/3403 ,  A61B2034/2051 ,  A61B2090/3954 ,  A61B2560/0223 ,  A61B2562/04 ,  G01R33/0017 ,  G01R33/0029 ,  G01R33/09

Abstract: A surgical locator circuit identifies a surgical target such as a kidney stone by disposing an emitter such as a magnetic source behind or adjacent the surgical target, and employing the circuit to identify an axis to the emitter, thus defining an axis or path to the surgical target. An array of sensors arranged in an equidistant, coplanar arrangement each senses a signal indicative of a distance to the emitter. A magneto resistor sensor generates a variable resistance is responsive to the distance to a magnetic coil emitting a magnetic field. An equal signal from each of the coplanar sensors indicates positioning on an axis passing through a point central to the sensors and orthogonal to the plane. A fixed element and signal conditioner augments and normalizes the signal received from each of the sensors to accommodate subtle differences in magneto resistive response among the plurality of sensors.

公开(公告)号：US09801542B2

公开(公告)日：2017-10-31

申请号：US14941494

申请日：2015-11-13

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Bao Tran ,  Ha Tran

IPC: A61B5/00 ,  A61B5/021 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/11 ,  A61B7/04 ,  G08B21/02 ,  A61B5/0205 ,  A61B5/01 ,  A61B5/03 ,  A61B5/1455 ,  A61B5/20 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/145 ,  A61B5/08 ,  A61B5/0215 ,  A61B5/022 ,  A61B5/024

CPC classification number: A61B5/0006 ,  A61B5/0008 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0026 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/021 ,  A61B5/0215 ,  A61B5/022 ,  A61B5/024 ,  A61B5/031 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0816 ,  A61B5/1112 ,  A61B5/1117 ,  A61B5/1128 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/201 ,  A61B5/411 ,  A61B5/4875 ,  A61B5/681 ,  A61B5/6826 ,  A61B5/6846 ,  A61B5/686 ,  A61B5/6891 ,  A61B5/7214 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/726 ,  A61B5/7267 ,  A61B5/7275 ,  A61B5/742 ,  A61B5/743 ,  A61B5/7465 ,  A61B7/04 ,  A61B2560/0233 ,  A61B2560/0412 ,  G06F19/00 ,  G08B21/02

Abstract: A heart monitoring system for a person includes one or more wireless nodes; and wearable appliance in communication with the one or more wireless nodes, the appliance monitoring vital signs.

公开(公告)号：US20170228506A1

公开(公告)日：2017-08-10

申请号：US15502243

申请日：2015-07-31

Applicant: Icahn School of Medicine at Mount Sinai

Inventor： Girish Nadkarni ,  Omri Gottesman ,  Stephen Bartlett Ellis ,  Erwin Bottinger

IPC: G06F19/00 ,  A61B5/20 ,  A61B5/00

CPC classification number: G16H50/20 ,  A61B5/201 ,  A61B5/7275 ,  A61B2218/00 ,  G06F19/324 ,  G16H10/60

Abstract: An example method of diagnosing chronic kidney disease (CKD) includes obtaining an electronic medical record for a patient having medical data. The medical data includes an indication if the patient had been previously diagnosed with CKD, an indication if the patient had previously undergone a kidney transplant, an indication if the patient had previously undergone a renal dialysis procedure, an indication if the patient had previously been diagnosed with another type of kidney disease, one or more glomerular filtration rate (GFR) measurements associated with the patient, an indication if the patient has type 2 diabetes, and/or an indication if the patient has hypertension. The method also includes automatically determining that the patient has CKD or does not have CKD based on the medical data in the electronic record.

公开(公告)号：US09707377B2

公开(公告)日：2017-07-18

申请号：US14087547

申请日：2013-11-22

Applicant: Catheter Precision, Inc.

Inventor： Todd J. Cohen ,  Dara McMahon ,  Robert C. Royce

IPC: A61M25/01 ,  A61B5/042 ,  A61B5/20 ,  A61B5/00 ,  A61B18/02 ,  A61B18/06 ,  A61B18/14 ,  A61B18/18 ,  A61F2/82 ,  A61N1/362 ,  A61N1/39 ,  A61N5/10 ,  A61B34/00 ,  A61B34/37 ,  A61B90/40 ,  A61B34/30

CPC classification number: A61M25/0105 ,  A61B5/042 ,  A61B5/201 ,  A61B5/4839 ,  A61B5/6852 ,  A61B18/0206 ,  A61B18/06 ,  A61B18/1492 ,  A61B18/1815 ,  A61B34/30 ,  A61B34/37 ,  A61B34/70 ,  A61B34/71 ,  A61B34/76 ,  A61B90/40 ,  A61B2034/301 ,  A61F2/82 ,  A61M25/0113 ,  A61M25/0133 ,  A61M25/0136 ,  A61N1/362 ,  A61N1/39 ,  A61N5/10

Abstract: Embodiment methods of treating a human or animal patient using a remotely controlled robotic catheter device inserting a handle of a catheter into a handle controller, inserting the catheter tubular portion into a resealable delivery channel forming a sterile barrier to a sled base, engaging a tip of the catheter with a sterile introducer disposed at an end of the sled base and engaged with the patient's body, positioning the catheter into the patient's body by remotely sending commands to the tele-robotic device to cause the sled member to advance toward the patient's body, and performing a diagnostic or therapeutic procedure on the patient using the catheter. Diagnostic or therapeutic procedures may include a mapping procedure, an ablation procedure, an angioplasty procedure, a drug delivery procedure; an electrophysiology procedure, a radiological procedure, and a medical device implantation or positioning procedure.

公开(公告)号：US20170196576A1

公开(公告)日：2017-07-13

申请号：US15402946

申请日：2017-01-10

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jerry Long ,  Timothy Harrah ,  Aaron Kirkemo ,  Brandon Craft ,  Elizabeth Stokley ,  Sebastian Koerner ,  Chad Schneider

IPC: A61B17/22 ,  A61B5/20 ,  A61B6/00 ,  A61M25/10 ,  A61M25/00 ,  A61M3/02

CPC classification number: A61B17/22 ,  A61B5/201 ,  A61B6/12 ,  A61B6/481 ,  A61B6/487 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22084 ,  A61B2217/005 ,  A61B2217/007 ,  A61M3/005 ,  A61M3/0204 ,  A61M3/0208 ,  A61M3/022 ,  A61M3/0295 ,  A61M25/10 ,  A61M2025/1052 ,  A61M2039/0276 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/3379 ,  A61M2205/50 ,  A61M2210/005 ,  A61M2210/1078 ,  A61M2210/1082 ,  A61M2210/1085 ,  A61M2210/1089

Abstract: Irrigation devices, methods, and systems are disclosed. The system comprises a catheter with one or more lumens and an expandable portion. One or more pumps are used to supply a mixture of contrasting and dilating agents in an interior kidney volume and flush a portion of the mixture out of the interior kidney volume. The method comprises placing a catheter into the interior kidney volume through a ureter, occluding a portion of the ureter with a distal end of the catheter, forming an exit port through an exterior kidney surface, flowing the contrasting and dilating agents through the one or more lumens to supply the mixture in the interior kidney volume, and flushing a portion of the mixture out of the exit port.

公开(公告)号：US09632094B2

公开(公告)日：2017-04-25

申请号：US13060260

申请日：2009-08-20

Applicant: Norbert Gretz ,  Johannes Pill ,  Daniel Schock-Kusch ,  Thomas Walter ,  Jürgen Hesser ,  Maliha Sadick ,  Felix Eickemeyer ,  Jae Hyung Hwang ,  Christian Schildknecht ,  Soichi Watanabe ,  Wolfgang Wach ,  Thomas Rose

Inventor： Norbert Gretz ,  Johannes Pill ,  Daniel Schock-Kusch ,  Thomas Walter ,  Jürgen Hesser ,  Maliha Sadick ,  Felix Eickemeyer ,  Jae Hyung Hwang ,  Christian Schildknecht ,  Soichi Watanabe ,  Wolfgang Wach ,  Thomas Rose

IPC: A61B5/00 ,  G01N33/58 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/20 ,  A61K49/00

CPC classification number: A61B5/201 ,  A61B5/0002 ,  A61B5/0071 ,  A61B5/0082 ,  A61B5/145 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/6832 ,  A61B5/6833 ,  A61B90/39 ,  A61B2090/3941 ,  A61B2560/0219 ,  A61B2560/0412 ,  A61K49/0043 ,  G01N33/582 ,  G01N2800/065 ,  G01N2800/28 ,  G01N2800/347

Abstract: A sensor plaster (116) for the transcutaneous measurement of an organ function, more particularly of a kidney function, is proposed. The sensor plaster (116) comprises at least one flexible carrier element (134) having at least one adhesive surface (138) which can be stuck onto a body surface. Furthermore, the sensor plaster (116) comprises at least one radiation source, more particularly a light source (142), wherein the radiation source is designed to irradiate the body surface with at least one interrogation light (162). Furthermore, the sensor plaster (116) comprises at least one detector (146) designed to detect at least one response light (176) incident from the direction of the body surface.