公开(公告)号：US08869635B2

公开(公告)日：2014-10-28

申请号：US13261191

申请日：2010-09-08

Applicant: MacDonald Daniel ,  Steven Raymond ,  David L. Reynolds

Inventor： MacDonald Daniel ,  Steven Raymond ,  David L. Reynolds

IPC: G01N1/14 ,  B01F13/00 ,  B01F15/02 ,  A61J1/20

CPC classification number: A61J1/2096 ,  A61J1/1425 ,  A61J1/201 ,  A61J1/2051 ,  B01F13/002 ,  B01F13/0022 ,  B01F15/0212 ,  B01F15/0223

Abstract: A transfer device (10) which comprises an outer housing (24), an inner body (26) formed within the housing (24), the inner body (26) having a conduit (66) extending therethrough to provide fluid communication between upper and lower chambers, the conduit (66) having a piercing tip (68) at a lower end, a cap (54)having a top wall and a downwardly extending wall (58), the cap being retained in position such that access cannot be had to the inner body (26), and a pushing member (44) which has at least one leg (48) extending upwardly, the pushing member having an activated position where the leg (48) will extend upwardly to the upper chamber and move the cap (54) such that access may be had to the inner body (26).

Abstract translation: 一种转移装置（10），包括外壳体（24），形成在壳体（24）内部的内部主体（26），内部主体（26）具有延伸穿过其中的导管（66），以提供上部和 所述导管（66）在下端具有穿刺尖端（68），具有顶壁和向下延伸的壁（58）的帽（54），所述帽保持在适当的位置，使得不能进入 以及具有向上延伸的至少一个腿部（48）的推动构件（44），所述推动构件具有启动位置，其中所述腿部（48）将向上延伸到所述上部腔室并且使所述推动构件 帽（54），使得可能对内部主体（26）进行接近。

公开(公告)号：US08852145B2

公开(公告)日：2014-10-07

申请号：US13884981

申请日：2011-10-27

Applicant: Igor Denenburg ,  Nimrod Lev ,  Moshe Gilboa

Inventor： Igor Denenburg ,  Nimrod Lev ,  Moshe Gilboa

IPC: A61M37/00 ,  A61M5/32 ,  A61J1/20

CPC classification number: A61M5/3294 ,  A61J1/201 ,  A61J1/2096

Abstract: Inline liquid drug medical devices for use with a source of physiological fluid and a medicinal vessel for liquid drug reconstitution and administration purposes. The inline liquid drug medical devices include a housing having a longitudinal device axis, a rotary flow control member and a vial adapter for transposing the flow control member from an initial first flow control position for liquid drug reconstitution purposes to a second flow control position for liquid drug administration purposes. The inline liquid drug medical devices include a syringe port and a drug dispensing port co-axial with the device axis. The rotary flow control member is rotatable about an axis of rotation co-axial with the syringe port and the drug dispensing port.

Abstract translation: 用于生理液体来源的液体药物医疗装置和用于液体药物重建和给药目的的药物容器。 在线液体药物医疗装置包括具有纵向装置轴线的壳体，旋转流量控制构件和用于将流量控制构件从用于液体药物重建目的的初始第一流量控制位置转移到液体的第二流量控制位置的小瓶适配器 药物管理目的。 在线液体药物医疗装置包括与装置轴线同轴的注射器端口和药物分配口。 旋转流量控制构件可以围绕与注射器端口和药物分配端口同轴的旋转轴线旋转。

公开(公告)号：US20140261727A1

公开(公告)日：2014-09-18

申请号：US13829268

申请日：2013-03-14

Applicant: George Michel MANSOUR ,  Tyler Devin PANIAN

Inventor： George Michel MANSOUR ,  Tyler Devin PANIAN

IPC: A61J1/20

CPC classification number: A61J1/20 ,  A61J1/065 ,  A61J1/1406 ,  A61J1/1481 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2072 ,  Y10T137/0402 ,  Y10T137/598

Abstract: A vial adapter for side engagement of a vial cap includes a needleless connector having a housing and defining one or more fluid pathways therein; an elongated piercing spike operatively coupled to the needleless connector, the elongated piercing spike having a longitudinal axis and one or more channels for fluid connectivity with the one or more fluid pathways; at least one housing arm coupled to the housing and extending parallel to the longitudinal axis; and a coupling member configured to orthogonally receive a vial cap with respect to the longitudinal axis, the coupling member having a planar surface, an aperture of the planar surface longitudinally aligned with the elongated piercing spike, and at least one support arm extending from the planar surface operatively coupled with the at least one housing arm to allow relative longitudinal movement between the coupling member and the elongated piercing spike.

Abstract translation: 用于小瓶盖的侧接合的小瓶适配器包括具有外壳并在其中限定一个或多个流体通路的无针连接器; 细长的穿刺尖钉可操作地联接到无针连接器，细长的穿刺尖钉具有纵向轴线和一个或多个通道，用于与一个或多个流体通道的流体连通性; 至少一个壳体臂，其联接到所述壳体并且平行于所述纵向轴线延伸; 以及联接构件，其被配置为相对于所述纵向轴线正交地接收小瓶盖，所述联接构件具有平坦表面，所述平坦表面的孔与所述细长穿孔尖端纵向对齐，以及至少一个支撑臂， 表面与所述至少一个外壳臂可操作地联接，以允许所述联接构件和所述细长穿刺尖之间的相对纵向运动。

公开(公告)号：US08827978B2

公开(公告)日：2014-09-09

申请号：US12678625

申请日：2007-09-17

Applicant: Anna Ellstrom

Inventor： Anna Ellstrom

IPC: A61B19/00 ,  A61J1/20 ,  A61J1/10 ,  A61J1/14

CPC classification number: A61J1/20 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1481 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2065

Abstract: The present invention concerns an attachable membrane device for providing a piercable liquid barrier membrane to the surface of a pierceable fluid container, such as an infusion bag. The attachable membrane device have a fastening part comprising a fastening surface adapted to be attached to the surface of the pierceable fluid container and thereby provide a liquid tight seal between the fastening surface and the surface of the pierceable fluid container. Additionally, the attachable membrane device is further provided with a barrier membrane part, adapted to provide a liquid tight seal after penetration by a piercing member. Connection means is arranged to the attachable membrane device. The invention simplifies the injection or withdrawal of a fluid in a pierceable fluid container.

Abstract translation: 本发明涉及一种用于在可刺穿的流体容器（例如输液袋）的表面上提供可穿透液体阻隔膜的可附接膜装置。 可连接膜装置具有紧固部分，该紧固部分包括适于附接到可刺穿流体容器的表面的紧固表面，从而在紧固表面和可刺穿流体容器的表面之间提供液密密封。 此外，可附接膜装置还设置有阻挡膜部分，适于在穿刺构件穿透之后提供液密密封。 连接装置设置在可连接膜装置上。 本发明简化了可渗透流体容器中的流体的注入或抽出。

公开(公告)号：US20140246342A1

公开(公告)日：2014-09-04

申请号：US14274441

申请日：2014-05-09

Applicant: John Domkowski ,  Eric John Schmidt

Inventor： John Domkowski ,  Eric John Schmidt

IPC: A61J1/20

CPC classification number: A61J1/2089 ,  A61J1/065 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1425 ,  A61J1/1481 ,  A61J1/20 ,  A61J1/201 ,  A61J1/2041 ,  A61J1/2055

Abstract: A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Abstract translation: 一种用于混合两个容器内容物的系统和方法。 该系统包括第一容器，第二容器和用于在第一和第二容器之间提供流体连通的连接器。 连接器包括用于将第一容器固定到连接器的至少一个弹性保持构件。 此外，连接器容纳包含例如药物的标准小瓶，并且防止小瓶内容物不期望地排放到环境中。

公开(公告)号：US08790328B2

公开(公告)日：2014-07-29

申请号：US13123685

申请日：2009-10-15

Applicant: Lasse Kragelund ,  John Thrane Hansen

Inventor： Lasse Kragelund ,  John Thrane Hansen

IPC: A61J1/14

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2037 ,  A61J1/2062 ,  A61J1/2075 ,  A61J1/2096 ,  A61M5/162 ,  A61M2039/0027

Abstract: A mixing system (1) adapted to allow first contents of a first container (2) and second contents of a second container (3) to mix to form a material. The mixed material is retrieved to a syringe (20) without being foamed. The mixing system (1) comprises a transfer unit (5) which is adapted to receive the first container (2) at a first port (11), the second container (3) at a second port (12) and the syringe (20) at a third port (13). The transfer unit (5) further houses a number of fluid pathways (14, 15, 16) interconnecting the three ports (11, 12, 13) as well as a number of flow control members (17, 18, 19, 22) for controlling fluid flow between the containers (2, 3) and the syringe (20). At least one of the flow control members (17, 18, 19, 22) allows a user to switch between two states of fluid flow, one in which fluid flow is enabled between the first port (11) and the third port (13) as well as between the third port (13) and the second port (12), and one in which fluid flow is enabled between the second port (12) and the third port (13). The invention also relates to a transfer unit comprising first and second ports for receiving first and second containers, respectively, a third port for coupling to a syringe, a number of fluid pathways interconnecting the ports, at least one flow control member which allows a user to switch between two states of fluid flow, and a locking means to ensure that the at least one flow control member can only be manipulated when a syringe is coupled to the third port.

Abstract translation: 一种适于允许第一容器（2）的第一内容物和第二容器（3）的第二内容物混合以形成材料的混合系统（1）。 将混合的材料回收到注射器（20）而不发泡。 混合系统（1）包括转移单元（5），其适于在第一端口（11）处容纳第一容器（2），第二容器（3）在第二端口（12）和注射器（20） ）在第三端口（13）。 传送单元（5）还容纳多个互连三个端口（11,12,13）的流体路径（14,15,16）以及多个流量控制构件（17,18,19,22），用于 控制容器（2,3）和注射器（20）之间的流体流动。 至少一个流量控制构件（17,18,19,22）允许使用者在两个流体流动状态之间切换，其中流体流在第一端口（11）和第三端口（13）之间启用， 以及在第三端口（13）和第二端口（12）之间以及在第二端口（12）和第三端口（13）之间能够进行流体流动的端口。 本发明还涉及一种转移单元，其包括用于分别接收第一和第二容器的第一和第二端口，用于连接到注射器的第三端口，将端口互连的多个流体通路，允许使用者的至少一个流量控制构件 以在两种流体流动状态之间切换，以及锁定装置，以确保只有当注射器联接到第三端口时，才能操纵至少一个流量控制构件。

公开(公告)号：US20140183096A1

公开(公告)日：2014-07-03

申请号：US14136779

申请日：2013-12-20

Applicant: Hospira, Inc.

Inventor： Robert John Oshgan ,  John C. Tanner, II

IPC: A61J3/00

CPC classification number: A61J1/2096 ,  A61J1/062 ,  A61J1/1406 ,  A61J1/201 ,  Y10T29/49826

Abstract: Methods and systems for a cartridge assembly for use with an injection system are provided. An example cartridge assembly may include an ampule containing a pharmaceutical product that is sealed at a distal end with a pierceable diaphragm. The cartridge assembly may also include a hub comprising a proximal portion defining a cavity that is configured to engage the distal end of the ampule and a piercing member positioned within the cavity. The piercing member may include a fluid pathway between a proximal end portion comprising an opening and a distal end in fluid communication with a distal opening of the hub. The proximal end portion may engage the pierceable diaphragm, and the piercing member may apply a force to the pierceable diaphragm in the inactivated position without penetrating the pierceable diaphragm.

Abstract translation: 提供了用于与注射系统一起使用的药筒组件的方法和系统。 示例性墨盒组件可以包括安瓿，其包含药物产品，所述药物产品在远端用可刺破的隔膜密封。 墨盒组件还可以包括毂，该毂包括限定腔体的近端部分，所述腔体构造成接合安瓿的远端以及定位在腔体内的刺穿构件。 刺穿构件可以包括在包括开口的近端部分和与毂的远侧开口流体连通的远端之间的流体通路。 近端部分可以接合可刺穿的隔膜，并且刺穿构件可以在不穿透可穿透隔膜的情况下在非活动位置向可刺穿隔膜施加力。

公开(公告)号：US20140183094A1

公开(公告)日：2014-07-03

申请号：US14199325

申请日：2014-03-06

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Masaomi IMAI ,  Takaaki Hiranuma

IPC: A61J1/14 ,  A61J1/20

CPC classification number: A61J1/2096 ,  A61J1/00 ,  A61J1/16 ,  A61J1/201 ,  A61J1/2072 ,  A61J3/002 ,  A61J2200/50

Abstract: A medical container includes: a container body, a mouth section through which liquid can enter and exit, a proximal-end opening, and a proximal-end edge portion surrounding the proximal-end opening; a plug body that seals the mouth section; a bag body having a bag-like shape and including an edge portion that is tightly fixed to the proximal-end edge portion and seals the proximal-end opening, and a reversing part which is surrounded by the edge portion, has flexibility, and is reversed inside/outside; and a space surrounded by the container body, the plug body and the bag body. The reversing part is reversed inside/outside when the liquid enters and exits the space through the mouth section, whereby the reversing part can take a first state in which the reversing part expands toward a distal end side, and a second state in which the reversing part expands toward the proximal end side.

Abstract translation: 医疗容器包括：容器主体，液体可以进出的口部，近端开口和围绕近端开口的近端缘部; 密封嘴部的塞体; 具有袋状形状的袋体，其包括紧密地固定在基端边缘部上并密封基端开口部的边缘部，并且由边缘部包围的反转部具有柔性，为 内/外翻 以及由容器主体，插头主体和袋体包围的空间。 当液体通过口部进入和离开空间时，反转部分在内部/外部反转，从而反转部分可以进入反向部分向远端侧膨胀的第一状态和第二状态，其中反转部分 部分向近端侧扩张。

公开(公告)号：US08734420B2

公开(公告)日：2014-05-27

申请号：US13402560

申请日：2012-02-22

Applicant: Scott R. Ariagno ,  Mark D. Schilling ,  Tomas V. Pla

Inventor： Scott R. Ariagno ,  Mark D. Schilling ,  Tomas V. Pla

IPC: A61J1/20

CPC classification number: A61J1/2089 ,  A61J1/16 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2065 ,  A61J1/2075 ,  A61J1/2082

Abstract: A package assembly for a drug reconstitution assembly includes a body, a drug reconstitution assembly and a removable lid. The body includes a plurality of protrusions configured to mate with a plurality of corresponding features of the drug reconstitution assembly to inhibit axial and rotational translation of the drug reconstitution assembly and its constituent parts during shipping and handling. By preventing axial and rotational shifting during shipment, premature and accidental puncture or contamination of the medication or the spikes within the drug reconstitution assembly is minimized.

Abstract translation: 用于药物重建组件的包装组件包括主体，药物重建组件和可拆卸盖。 主体包括多个突起，其被配置为与药物重建组件的多个对应特征配合，以在运输和处理期间抑制药物重建组件及其组成部件的轴向和旋转平移。 通过在运输期间防止轴向和旋转移动，使药物重建组件内的药物或尖峰的过早和意外的穿刺或污染被最小化。

公开(公告)号：US20140124092A1

公开(公告)日：2014-05-08

申请号：US14156514

申请日：2014-01-16

Applicant: Valeritas, Inc.

Inventor： Robert R. Gonnelli ,  Robert L. Standley ,  Steven F. Levesque

IPC: B65B3/26

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2017 ,  A61J1/2037 ,  A61J1/2058 ,  A61J1/2072 ,  A61J1/2096 ,  B65B3/26 ,  G01F11/262 ,  Y10T137/8593

Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.

Abstract translation: 用于在供应储存器和填充储存器之间传送流体的流体转移装置包括计量储存器和歧管，该歧管形成与计量储存器流体连接的第一通道的至少一部分。 第一通道包括从歧管延伸的第一套管。 歧管形成与计量储存器流体连接的第二通道的至少一部分。 第二通道包括从歧管延伸的第二套管。 第三通道延伸穿过歧管并且包括第三插管，其具有靠近第一插管的远端的第一端和靠近第二插管的远端的第二端。 第一止回阀设置在第一通道内，第二止回阀设置在第二通道内。