公开(公告)号：US20160166211A1

公开(公告)日：2016-06-16

申请号：US14950467

申请日：2015-11-24

Applicant: HeartWare, Inc.

Inventor： Michael C. Brown ,  Carlos Reyes

IPC: A61B5/00 ,  A61B5/0215 ,  A61M1/10 ,  A61M1/12

CPC classification number: A61B5/7278 ,  A61B5/0215 ,  A61M1/101 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3334 ,  A61M2205/35

Abstract: The present disclosure provides for a method of monitoring the mean arterial pressure of a patient having a blood pump. The method may involve identifying a segment of time associated with diastole of the patient's cardiac cycle, determining a first parameter of the blood pump corresponding to the identified segment of time, and estimating the mean arterial pressure of the patient based at least in part on the first parameter.

Abstract translation: 本公开提供了一种监测具有血液泵的患者的平均动脉压的方法。 该方法可以包括识别与患者的心动周期的舒张相关联的时间段，确定对应于所识别的时间段的血液泵的第一参数，以及至少部分地根据患者的心脏周期估计患者的平均动脉压 第一个参数。

公开(公告)号：US09278168B2

公开(公告)日：2016-03-08

申请号：US13928324

申请日：2013-06-26

Applicant: Thoratec LLC

Inventor： Barry N. Gellman ,  Andrew Koert ,  Zhongjun Wu ,  Juntao Zhang ,  Bartley P. Griffith

IPC: A61M1/16 ,  A61M1/10 ,  A61M1/26

CPC classification number: A61M1/1698 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/262 ,  A61M1/267 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3334

Abstract: An integrated centrifugal blood pump-oxygenator (1) which has a housing (2) with a top (3) having a blood inlet (4), a blood outlet (5) and a gas inlet (6), and a bottom (7) having a rotational body (8) being rotatably arranged in a rotor-housing (9) of the bottom (7). The integrated centrifugal blood pump-oxygenator (1) further has an oxygenator membrane (10) provided in an interior (11) of the housing (2), wherein in the operation state oxygen (12) is transferred from the gas inlet (6) through the oxygenator membrane (10) to a gas outlet (13) and blood (14) is brought in direct contact with the oxygenator membrane (10) by pumping the blood (14) with the rotational body (8) from the blood inlet (4) to the blood outlet (5). The rotational body (8) is magnetically journalled in a contact-free manner with respect to the rotor-housing (9). There is an extracorporeal life support system (1000), and a method of de-bubbling and priming a extracorporeal life support system (1000).

公开(公告)号：US20160022887A1

公开(公告)日：2016-01-28

申请号：US14874251

申请日：2015-10-02

Applicant: OregonHeart, Inc.

Inventor： Richard Wampler

IPC: A61M1/10

CPC classification number: A61M1/1036 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/3334

Abstract: A total artificial heart having a rotor with an impeller, wherein the rotor is mounted within a pump housing on a hollow shaft. The rotor is magnetically driven to produce rotary motion of the impeller for pumping blood. The motor is disposed within the pump housing such that axial translation within the housing acts as a shuttle valve to alternate flow between pulmonary and systemic circulation.

Abstract translation: 具有带叶轮的转子的总人造心脏，其中转子安装在泵壳体中的空心轴上。 转子被磁力驱动以产生用于泵送血液的叶轮的旋转运动。 电动机设置在泵壳体内，使得壳体内的轴向平移作为梭阀来交换肺和全身循环之间的流动。

公开(公告)号：US20150374906A1

公开(公告)日：2015-12-31

申请号：US14852660

申请日：2015-09-14

Applicant: MILUX HOLDING S.A.

Inventor： Peter FORSELL

IPC: A61M5/142 ,  A61B5/00 ,  A61N1/05 ,  A61B5/07 ,  A61M5/145 ,  A61F5/00 ,  A61F2/12 ,  A61F2/28 ,  A61M27/00 ,  A61M39/22 ,  A61M31/00 ,  A61F2/00

CPC classification number: A61M5/14276 ,  A61B5/076 ,  A61B5/686 ,  A61B2017/00039 ,  A61B2017/00402 ,  A61B2017/00539 ,  A61B2090/061 ,  A61F2/0036 ,  A61F2/004 ,  A61F2/12 ,  A61F2/28 ,  A61F5/0013 ,  A61F2002/485 ,  A61F2250/0001 ,  A61F2250/0002 ,  A61F2250/0004 ,  A61F2310/00023 ,  A61F2310/00047 ,  A61F2310/00161 ,  A61F2310/00179 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1025 ,  A61M1/1031 ,  A61M1/1032 ,  A61M1/1036 ,  A61M1/1055 ,  A61M1/106 ,  A61M1/1068 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M5/14526 ,  A61M27/002 ,  A61M31/002 ,  A61M39/22 ,  A61M2205/0272 ,  A61M2205/103 ,  A61M2205/32 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3365 ,  A61M2205/3515 ,  A61M2205/3538 ,  A61M2210/1021 ,  A61N1/05 ,  A61N1/3787 ,  F04B43/12 ,  F04B43/1253 ,  F04C2/10 ,  F04C11/008 ,  F04C13/001 ,  F04C15/0061 ,  F04C15/0069 ,  F04C2240/40

Abstract: An operable implant adapted to be implanted in the body of a patient. The operable implant comprising an operation device and a body engaging portion, the operation device comprises an electrical motor comprising a static part comprising a plurality of coils and a movable part comprising a plurality of magnets, such that sequential energizing of said coils magnetically propels the magnets and thus propels the movable part. The operation device further comprises an enclosure adapted to hermetically enclose the coils of the static part, such that a seal is created between the static part and the propelled moving part with the included magnets, such that the coils of the static part are sealed from the bodily fluids, when implanted.

Abstract translation: 适于植入患者体内的可操作的植入物。 所述可操作植入物包括操作装置和主体接合部分，所述操作装置包括电动马达，其包括包括多个线圈的静止部分和包括多个磁体的可移动部分，使得所述线圈的顺序通电磁力推动所述磁体 从而推动可动部件。 所述操作装置还包括适于气密地包围所述静止部件的线圈的外壳，使得在所述静止部件和所述被驱动的移动部件之间产生具有所述磁体的密封，使得所述静止部件的所述线圈 体液植入时。

公开(公告)号：US09180235B2

公开(公告)日：2015-11-10

申请号：US13123231

申请日：2009-10-12

Applicant: Peter Forsell

Inventor： Peter Forsell

IPC: A61N1/362 ,  F04B35/00 ,  A61M1/10 ,  A61F2/01 ,  A61M1/12

CPC classification number: A61M1/1031 ,  A61F2/01 ,  A61F2230/005 ,  A61M1/1001 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1036 ,  A61M1/122 ,  A61M1/125 ,  A61M1/127 ,  A61M2205/32 ,  A61M2205/8243

Abstract: The present invention relates to a heart pump apparatus comprising a turbine pump for assisting the heart of a human patient. The invention is based on the realization that a turbine without a center axis would improve the capacity of the heart help pump apparatus. The present invention also relates to a turbine pump system for assisting the heart of a human patient. The present invention also relates to operation methods and methods for surgically placing a rotating body of a turbine pump and a stator of a turbine pump in a patient.

Abstract translation: 本发明涉及一种包括用于辅助人类患者的心脏的涡轮泵的心脏泵装置。 本发明基于以下认识：没有中心轴的涡轮机将改善心脏帮助泵装置的容量。 本发明还涉及一种用于辅助人类患者的心脏的涡轮泵系统。 本发明还涉及将涡轮泵的旋转体和涡轮泵的定子手术放置在患者体内的操作方法和方法。

公开(公告)号：US09173985B2

公开(公告)日：2015-11-03

申请号：US14083752

申请日：2013-11-19

Applicant: Richard Wampler

Inventor： Richard Wampler

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1036 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/3334

Abstract: A total artificial heart having a rotor with an impeller, wherein the rotor is mounted within a pump housing on a hollow shaft. The rotor is magnetically driven to produce rotary motion of the impeller for pumping blood. The motor is disposed within the pump housing such that axial translation within the housing acts as a shuttle valve to alternate flow between pulmonary and systemic circulation.

Abstract translation: 具有带叶轮的转子的总人造心脏，其中转子安装在泵壳体中的空心轴上。 转子被磁力驱动以产生用于泵送血液的叶轮的旋转运动。 电动机设置在泵壳体内，使得壳体内的轴向平移作为梭阀来交换肺和全身循环之间的流动。

公开(公告)号：US20150273125A1

公开(公告)日：2015-10-01

申请号：US14735990

申请日：2015-06-10

Applicant: Thoratec Corporation

Inventor： Kevin Bourque

IPC: A61M1/10 ,  A61M1/12 ,  F04D13/06

CPC classification number: A61M1/1036 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/3365 ,  F04D13/0606 ,  F04D13/0633 ,  F04D13/064 ,  F04D13/0646 ,  F04D29/048 ,  Y10T29/49009

Abstract: A method for assisting blood circulation in a patient includes drawing a flow of blood from a patient's heart into a blood flow channel formed by a housing. The flow of blood is passed through a motor stator to a rotor disposed within the blood flow channel. The motor stator is arranged circumferentially around the blood flow channel. The rotor has permanent magnetic poles for magnetic levitation and rotation of the rotor. The motor stator is controlled to act as a radial bearing for magnetic levitation of the rotor and to rotate the rotor within the blood flow channel. The rotor is levitated within the blood flow channel in the direction of the rotor axis of rotation via passive magnetic interaction between the rotor and the motor stator. The flow of blood is output from the blood flow channel to the patient.

Abstract translation: 用于辅助患者血液循环的方法包括将血液从患者的心脏流入由壳体形成的血流通道。 血流通过马达定子到位于血流通道内的转子。 马达定子围绕血流通道周向布置。 转子具有用于磁悬浮和转子旋转的永久磁极。 电动机定子被控制成用作用于转子磁悬浮并使转子在血流通道内旋转的径向轴承。 转子通过转子和电动机定子之间的无源磁性相互作用在转子旋转轴线的方向在血流通道内悬浮。 血流从血流通道输出到患者身上。

公开(公告)号：US09132215B2

公开(公告)日：2015-09-15

申请号：US13579239

申请日：2011-01-20

Applicant: Takayoshi Ozaki ,  Hiroyuki Yamada ,  Kenichi Suzuki ,  Ken Sugiura

Inventor： Takayoshi Ozaki ,  Hiroyuki Yamada ,  Kenichi Suzuki ,  Ken Sugiura

IPC: A61M1/10 ,  F04D13/06 ,  F04D29/048

CPC classification number: A61M1/1036 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  F04D13/0633 ,  F04D13/0666 ,  F04D29/048

Abstract: This centrifugal blood pump apparatus includes an impeller provided in a blood chamber, a permanent magnet provided in one surface of the impeller, and a permanent magnet provided in an inner wall of the blood chamber, for attracting the permanent magnet. A centerline of the permanent magnet is arranged at a position different from that of a centerline of a sidewall of the blood chamber such that a rotation centerline of the impeller matches the centerline of the sidewall of the blood chamber during pump operation. Therefore, high torque transmission efficiency is obtained.

Abstract translation: 该离心式血液泵装置包括设置在血液室中的叶轮，设置在叶轮的一个表面中的永磁体和设置在血液室的内壁中的用于吸引永磁体的永磁体。 永磁体的中心线布置在与血液室的侧壁的中心线不同的位置处，使得在泵操作期间叶轮的旋转中心线与血液室的侧壁的中心线匹配。 因此，获得高转矩传递效率。

公开(公告)号：US20150231318A1

公开(公告)日：2015-08-20

申请号：US14422003

申请日：2013-08-19

Applicant: Oran BULENT ,  Oran OMER FARUK ,  Avci ELIFORAN

Inventor： Oran Bulent ,  Oran Omer Faruk ,  Avci Elif Oran

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/12 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  A61M1/127 ,  A61M2205/0238 ,  A61M2205/3334 ,  A61M2205/8243 ,  A61M2210/12 ,  A61M2230/04

Abstract: The invention is a new generation permanent heart assist device developed to be installed into great arteries such as trans-aortic and trans-pulmonary artery to maintain blood circulation of the patients with end-stage heart failure. This device is a sort of brushless, synchronous, servo, electric motor which uses direct driver technology. It consumes little energy and provides high blood flow. The specially designed hollow rotor without a pivot pin provides enough blood flow to the patient by pushing the blood forward with the helical winglets inside it. The risk of thromboembolic events on the foreign surface that contacts with blood is less than in the counterparts of this device. Finally, the invention; is a curved permanent heart assist device that is applied on the aortas, reinforced twice with double stators and designed in smaller size so as not to compress surrounding tissues and organs.

Abstract translation: 本发明是一种新一代的永久性心脏辅助装置，其被开发用于安装在大动脉中，例如主动脉和反向肺动脉，以维持终末期心力衰竭患者的血液循环。 该装置是一种使用直接驱动技术的无刷，同步，伺服，电动马达。 它消耗少量能量并提供高血流量。 没有枢轴销的专门设计的中空转子通过将血液向前推入患者内部的螺旋小翼提供足够的血液流动。 与血液接触的外来表面血栓栓塞事件的风险小于该装置的对应物。 最后，发明; 是一种应用于主动脉的弯曲永久性心脏辅助装置，用双重定位器加强两次，设计成较小的尺寸，以免压缩周围的组织和器官。

公开(公告)号：US09109601B2

公开(公告)日：2015-08-18

申请号：US14456740

申请日：2014-08-11

Applicant: Thoratec Corporation

Inventor： Takehisa Mori

IPC: F04B35/04 ,  F04D13/02 ,  A61M1/10 ,  F04D13/06 ,  F04D29/048 ,  F04D29/047

CPC classification number: F04D13/026 ,  A61M1/10 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1036 ,  F04D13/0666 ,  F04D29/047 ,  F04D29/048

Abstract: A blood pump apparatus includes a housing having a blood inlet port and blood outlet port, a pump unit including an impeller that rotates within the housing, and an impeller rotational torque generation section. The housing includes a plurality of magnetic members embedded between the impeller and the impeller rotational torque generation section for transmitting a magnetically attractive force generated by the impeller rotational torque generation section to an impeller body. The pump device includes a non-contact bearing mechanism for rotating the impeller without contacting with the inner surface of the housing when the impeller is rotated by the impeller rotational torque generation section.

Abstract translation: 一种血泵装置，具备：具有血液入口和血液出口的壳体，具有在壳体内旋转的叶轮的泵单元和叶轮旋转转矩产生部。 壳体包括嵌入在叶轮和叶轮旋转转矩产生部之间的多个磁性部件，用于将由叶轮旋转转矩产生部产生的磁力吸引力传递到叶轮体。 该泵装置包括一非接触轴承机构，用于当叶轮由叶轮旋转转矩产生部分旋转时，使叶轮旋转而不与壳体的内表面接触。