公开(公告)号：US3957865A

公开(公告)日：1976-05-18

申请号：US483331

申请日：1974-06-26

Applicant: Lothar Rohe ,  Jurgen Schramm ,  Erich Klauke ,  Ludwig Eue ,  Robert Rudolf Schmidt

Inventor： Lothar Rohe ,  Jurgen Schramm ,  Erich Klauke ,  Ludwig Eue ,  Robert Rudolf Schmidt

IPC: A01N37/34 ,  A01N31/14 ,  A01N31/16 ,  A01N33/22 ,  A01N41/10 ,  A01P13/00 ,  A01P13/02 ,  C07C67/00 ,  C07C201/00 ,  C07C205/38 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/44 ,  C07C319/20 ,  C07C323/20 ,  C07C323/62 ,  C07C325/00 ,  C07C327/00 ,  C07C327/48 ,  C07C125/00 ,  C07C145/00 ,  C07C153/00

CPC classification number: C07C317/00 ,  A01N31/16 ,  A01N33/22 ,  C07C323/00

Abstract: Halogenated 4-trifluoromethyl-diphenyl-ether compounds of the formula ##SPC1##In whichR.sup.1 is alkylthio of from 1 to 4 carbon atoms, alkylsulfinyl or alkylsulfonyl of from 1 to 4 carbon atoms, or aminothiocarbonyl;R.sup.2 is hydrogen or methyl;X.sup.1 is halogen; andX.sup.2 is hydrogen or halogen;Are outstandingly effective as herbicides, particularly as selective herbicides.

公开(公告)号：US3957861A

公开(公告)日：1976-05-18

申请号：US413647

申请日：1973-11-07

Applicant: Milton E. Herr ,  Roy A. Johnson

Inventor： Milton E. Herr ,  Roy A. Johnson

IPC: C07C67/00 ,  C07C201/00 ,  C07C205/45 ,  C07C205/56 ,  C07C227/00 ,  C07C227/18 ,  C07C229/42 ,  C07D303/48 ,  C07C79/46 ,  C07C101/447

CPC classification number: C07C205/45 ,  C07C205/56 ,  C07D303/48 ,  Y10S514/822

Abstract: In accordance with this invention, there are disclosed compounds of the formula ##SPC1##Wherein X is selected from the group consisting of nitro and amino with the proviso that when y is hydrogen, X is nitro; Y is selected from the group consisting of hydrogen and fluoro; R is selected from the group consisting of hydrogen and alkyl of from one to six carbon atoms, inclusive.These compounds are compounded into pharmaceutical compositions and administered to mammals for purposes of relieving inflammation and to mammals in need of prophylactic anti-thrombotic treatment.

公开(公告)号：US3954829A

公开(公告)日：1976-05-04

申请号：US483333

申请日：1974-06-26

Applicant: Lothar Rohe ,  Jurgen Schramm ,  Erich Klauke ,  Ludwig Eue ,  Robert Rudolf Schmidt

Inventor： Lothar Rohe ,  Jurgen Schramm ,  Erich Klauke ,  Ludwig Eue ,  Robert Rudolf Schmidt

IPC: A01N37/34 ,  A01N31/14 ,  A01N31/16 ,  A01N33/22 ,  A01N41/10 ,  A01P13/00 ,  A01P13/02 ,  C07C67/00 ,  C07C201/00 ,  C07C205/38 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/44 ,  C07C319/20 ,  C07C323/20 ,  C07C323/62 ,  C07C325/00 ,  C07C327/00 ,  C07C327/48 ,  C07C121/75

CPC classification number: C07C317/00 ,  A01N31/16 ,  A01N33/22 ,  C07C323/00

Abstract: Halogenated 4-trifluoromethyl-4'-cyano-diphenyl-ether compounds of the formula ##SPC1##In whichR is hydrogen, halogen, alkyl of from 1 to 4 carbon atoms, alkoxy of from 1 to 4 carbon atoms or alkylthio of from 1 to 4 carbon atoms,Are outstandingly effective as herbicides, particularly as selective herbicides.

Abstract translation: 卤化的4-三氟甲基-4'-氰基 - 二苯基醚化合物，其中R为氢，卤素，1至4个碳原子的烷基，1至4个碳原子的烷氧基或1至4个碳原子的烷硫基 原子，作为除草剂特别有效，特别是选择性除草剂。

公开(公告)号：US3932473A

公开(公告)日：1976-01-13

申请号：US353001

申请日：1973-04-20

Applicant: Erich Klauke ,  Reinhold Schmitz ,  Hans-Samuel Bien

Inventor： Erich Klauke ,  Reinhold Schmitz ,  Hans-Samuel Bien

IPC: C07C205/47 ,  C07C20060101 ,  C07C67/00 ,  C07C201/00 ,  C09B1/00 ,  C07C79/37

CPC classification number: C07C205/47

Abstract: Pure 1-nitro-anthraquinone is produced by nitrating anthraquinone in aqueous hydrogen fluoride containing about 5 - 30 weight percent of water with nitric acid as nitrating agent at about 0.degree. - 150.degree.C preferably 20.degree. - 70.degree.C.

Abstract translation: 通过在约0-150℃，优选20-70℃下，用硝酸作为硝化剂，将含有约5-30重量％水的氟化氢水溶液中的蒽醌硝化作为硝基化蒽醌。

公开(公告)号：US3840584A

公开(公告)日：1974-10-08

申请号：US19843471

申请日：1971-11-12

Applicant: PROCTER & GAMBLE

Inventor： CRAWFORD R

IPC: C07C69/74 ,  A01N53/02 ,  A01N53/10 ,  C07C67/00 ,  C07C201/00 ,  C07C313/00 ,  C07C317/22 ,  C07C323/19

CPC classification number: A01N53/00

Abstract: 1. A COMPOUND OF THE FORMULA

R-COO-R''

WHEREIN R IS A CYCLOPROPANE MOIETY SELECTED FROM THE GROUP CONSISTING OF

2,2,3,3-TETRA(H3C-)-CYCLOPROPYL-, 2,2-DI(H3C-),3-((H3C)2-

C=CH-)-CYCLOPROPYL-, AND 2,2-DI(H3C-),3-((-(CH2)N-)>C=

CH-)-CYCLOPROPYL-

WHEREIN N IS AN INTEGER OF FROM 4 TO 6 AND WHEREIN R'' IS A 1-ACEBNAPHTHENYL OR TEYRAHYDRO-1-ACENAPHTHENYL MOIETY OF THE FORMULA

X1,X2-ACENAPTHENE OR X1,X2-2A,3,4,5-TETRAHYDROACENAPTHENE

WHEREIN X1 AND X2 ARE EACH SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGEN, NITRO, THIOMETHYL, STRAIGHT OR BRANCHED CHAIN ALKYL CONTAINING FROM ABOUT 1 TO 5 CARBON ATOMS, ALKOXY CONTAINING FROM ABOUT 1 TO 2 CARBON ATOMS AND SULFONYLMETHYL.

公开(公告)号：US3822314A

公开(公告)日：1974-07-02

申请号：US5730470

申请日：1970-07-22

Applicant: RHONE POULENC SA

Inventor： GAY M ,  HOUDE M

IPC: C07C251/48 ,  C07C20060101 ,  C07C49/76 ,  C07C67/00 ,  C07C201/00 ,  C07C205/45 ,  C07C239/00 ,  C07C301/00 ,  C07C303/22 ,  C07C309/24 ,  C07D333/20 ,  C10L1/22 ,  C07C131/00

CPC classification number: C07C201/12 ,  C07C249/06 ,  C07C251/48 ,  C07C205/45

Abstract: NITROXIMES, WHICH CAN BE HYDROLYSED TO NITROKELONES, ARE MADE BY THE NITROSATION OF VINYL-BENZENES IN A REACTION MEDIUM COMPRISING WATER AND AN ORGANIC SOLVENT AT LEAST PARTIALLY SOLUBLE THEREIN.

公开(公告)号：US3819716A

公开(公告)日：1974-06-25

申请号：US31245672

申请日：1972-12-06

Applicant: MERCK & CO INC

Inventor： SHEN T ,  JONES H

IPC: C07C311/16 ,  A61K31/045 ,  A61K31/33 ,  C07C27/00 ,  C07C31/13 ,  C07C33/00 ,  C07C33/05 ,  C07C33/38 ,  C07C33/50 ,  C07C35/52 ,  C07C67/00 ,  C07C201/00 ,  C07C215/70 ,  C07C217/48 ,  C07C217/74 ,  C07C217/76 ,  C07C217/78 ,  C07C219/32 ,  C07C235/46 ,  C07C255/54 ,  C07C313/00 ,  C07C317/00 ,  C07C317/22 ,  C07C317/24 ,  C07C317/32 ,  C07C317/36 ,  C07C317/44 ,  C07C317/46 ,  C07C317/48 ,  C07C323/11 ,  C07C323/12 ,  C07C323/20 ,  C07D333/00 ,  C07C147/06

CPC classification number: C07C323/00 ,  C07C33/38 ,  C07C33/50 ,  C07C35/52 ,  C07C317/00

Abstract: NEW SUBSTITUTED INDENYL ALCOHOLS AND DERIVATIVES THEREOF WHICH HAVE ANTI-INFLAMMATORY, ANTI-PYRETIC AND ANALGESIC ACTIVITY. ALSO INCLUDED ARE METHODS OF PREPARING SAID INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS HAVING SAID INDENYL COMPOUNDS AS AN ACTIVE INGREDIENT AND METHODS OF TREATING INFLAMMATION.

公开(公告)号：US3390161A

公开(公告)日：1968-06-25

申请号：US31234163

申请日：1963-09-30

Applicant: BENDIX CORP

Inventor： FRAIOLI ANTHONY V

IPC: C07C201/00 ,  C07C201/16 ,  C22B3/26

CPC classification number: C22B3/0009 ,  C07C201/00 ,  C07C201/16 ,  Y02P10/234 ,  C07C207/04 ,  C07C205/25

公开(公告)号：US11247976B2

公开(公告)日：2022-02-15

申请号：US16097541

申请日：2017-04-30

Applicant: Wisconsin Alumni Research Foundation

Inventor： Helen Blackwell ,  Michelle E. Boursier ,  Joseph D. Moore

IPC: C07D307/33 ,  C07D333/36 ,  C07D207/09 ,  C07D207/273 ,  C07D307/14 ,  C07C233/06 ,  C07C233/61 ,  C07C235/22 ,  C07C201/00 ,  C07D307/22 ,  C07C233/58 ,  C07C233/60 ,  C07C233/32

Abstract: RhlR modulators including agonist and antagonists which are useful for modulating QS phenotypes in Gram-negative bacteria. Certain compounds of general formula A-W-HG having various carbocyclic ad heterocyclic head groups (HG) and various tail groups (A), where —W— is —CO—NH—, —SO2—NH—, —CO—NH—CH2—, or —SO2—NH—CH2— are RhlR agonists or antagonists. The compounds are useful in methods of modulating quorum sensing in Gram-negative bacteria, particularly in Pseudomonas. Compositions including certain RhlR modulators are useful for decreasing the virulence of Gram-negative bacteria. Pharmaceutical compositions comprising certain RhlR modulators are useful for treatment of infections of Gram-negative bacteria.

公开(公告)号：US10961180B2

公开(公告)日：2021-03-30

申请号：US16243232

申请日：2019-01-09

Applicant: Eastman Chemical Company

Inventor： Stephanie Kay Clendennen ,  Vasudev R. Bhonde ,  Damon Ray Billodeaux ,  Matthew Allen Boone ,  Kim Dumoleijn ,  Stijn Simonne Paul Van de Vyver ,  Kristof Moonen ,  Neil Warren Boaz

IPC: C09K8/584 ,  C07C207/02 ,  C07C201/00 ,  C11D1/75 ,  C11D1/83 ,  C11D1/835 ,  C11D1/94 ,  C10L1/18 ,  C11D3/39 ,  C11D11/00 ,  C11D3/43 ,  C09D7/63 ,  C11D3/395 ,  A01N41/08 ,  C07C311/32 ,  C07C211/08 ,  C09K8/524 ,  A01N37/44 ,  C07C291/04 ,  C07C45/74 ,  C07C215/10 ,  C07C45/62 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61Q5/02 ,  A61Q19/10 ,  C07C211/04 ,  C07C229/12 ,  C07C309/14 ,  C07H5/06 ,  C11D1/90 ,  A01N33/12 ,  B01J31/02 ,  C07C45/72 ,  C07C209/22 ,  C07C211/63 ,  C07C211/64

Abstract: The invention provides branched trialkylamine oxides with improved properties. The trialkylamine oxides of the invention produced from branched trialkylamines, in one embodiment, can be made using certain branched C10-12 enals and aldehydes. The invention also provides an trialkylamine oxide having the formula: wherein R5, R6 and R7 are independently at least one of C3H7, C2H5, CH3, or H, or mixtures thereof; and wherein R5 and R6 are not H at the same time. In one embodiment, the trialkylamine oxides of the invention can be useful in making various products, for example, as surfactants.