公开(公告)号：US10373048B2

公开(公告)日：2019-08-06

申请号：US14838013

申请日：2015-08-27

Applicant: Ecole Polytechnique Federale De Lausanne (EPFL)

Inventor： Henry Markram ,  Rodrigo de Campos Perin ,  Thomas K. Berger

IPC: G06N3/04 ,  G06N3/08

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by between-assembly links, each node assembly itself comprising a network of nodes interconnected by a plurality of within-assembly links, wherein each of the between-assembly links and the within-assembly links have an associated weight, each weight embodying a strength of connection between the nodes joined by the associated link, the nodes within each assembly being more likely to be connected to other nodes within that assembly than to be connected to nodes within others of the node assemblies.

公开(公告)号：US10352954B2

公开(公告)日：2019-07-16

申请号：US15029637

申请日：2014-10-14

Applicant: Ecole Polytechnique Fédérale de Lausanne (EPFL)

Inventor： David Vincent Bonzon ,  Georges Henri Muller ,  Philippe Renaud ,  Yann Barrandon

IPC: G01N35/10 ,  G01N15/02 ,  B01L3/02 ,  G01N15/12 ,  G01N15/10

Abstract: A sensing tip including a pipette tip having a cavity which communicates with an external environment of the pipette tip through an aperture located at a distal end of the pipette tip, and an impedance sensor having a sensing area including at least two electrodes located respectively outside and inside the pipette tip, wherein the sensing area is arranged within the aperture.

公开(公告)号：US10334163B2

公开(公告)日：2019-06-25

申请号：US15120527

申请日：2015-02-24

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Ömer Cogal ,  Yusuf Leblebici

IPC: H04N5/232 ,  A61B1/00 ,  A61B1/04 ,  A61B1/05 ,  A61B1/07 ,  G06T3/40 ,  H04N5/225 ,  G03B15/03 ,  G03B37/00 ,  H04N5/235 ,  H04N5/243 ,  H04N5/247 ,  A61B1/045 ,  G03B37/04

Abstract: A multi-camera hemispherical very wide field of view imaging apparatus with omnidirectional illumination capability comprises a cylindrical body (4, 4.a, 4.b), a hemispherical mechanical frame (2) arranged on one end of the cylindrical body (4, 4.a, 4.b), a plurality of imaging channels (3), each imaging channel (3) comprising at least an image sensor and related optics with a fixed focus appropriate for endoscopic imaging, the plurality of imaging channels (3) being distributed over the hemispherical mechanical frame (2), a light source arranged center-down at a back part of the plurality of imaging channels (3) and inside or at the end of the cylindrical body (4, 4.a, 4.b). Each imaging channel (3) comprises a plurality of lightning channels (1) around their center, each of the plurality of lightning channels (1) comprising at least one microfiber light guide having a determined angle of curvature arranged to transmit the light from the light source. The imaging apparatus further comprises a control and processing circuit (5) comprising a camera control unit (6), an illumination control unit (7), an illumination unit (8), a sample and capture unit (9), an image processing unit (10) and an output interface (11) to a PC. The camera control unit (6) is configured to power each of the plurality of imaging channels (3) and make automatic gain compensation for each imaging channel (3), the illumination control unit (7) is configured for automatic intensity dimming, the sample and capture unit (9) is an interface circuit for correct sampling, extraction and capturing frames of individual imaging channels (3), the image processing unit (10) is configured for constructing a spherical panoramic image by applying a determined algorithm, and the output interface (11) is arranged to output the spherical panoramic image to a system configured to visualize it.

公开(公告)号：US20190177696A1

公开(公告)日：2019-06-13

申请号：US16310137

申请日：2017-06-16

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Carmen UNZU EZQUERRO ,  Marc FRIEDLI ,  Didier TRONO ,  Barbara WILDHABER

IPC: C12N5/071

Abstract: The present invention relates to a method for preparing induced hepatic progenitor cells (iHPC) comprising the steps of dedifferentiation of hepatocytes by culture with a culture medium comprising at least one activator of the Wnt signaling, Basic fibroblast growth factor (b-FGF), and Epidermal growth factor (EGF).

公开(公告)号：US20190172937A1

公开(公告)日：2019-06-06

申请号：US16200718

申请日：2018-11-27

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Cem ALPER ,  Mihai Adrian IONESCU ,  Teodor ROSCA

IPC: H01L29/768 ,  H01L27/092 ,  H01L21/8238 ,  H01L21/02 ,  H01L21/8234

CPC classification number: H01L29/768 ,  H01L21/02241 ,  H01L21/0226 ,  H01L21/823406 ,  H01L21/8238 ,  H01L27/0922 ,  H01L29/165 ,  H01L29/66356 ,  H01L29/7391

Abstract: The present invention relates to a charge sensing device for sensing charge variations in a charge storage area including: a TFET having at least one sense gate; a capacitive coupling for coupling the charge storage area with the sense gate.

公开(公告)号：US10279177B2

公开(公告)日：2019-05-07

申请号：US15669208

申请日：2017-08-04

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Jocelyne Bloch ,  Grégoire Courtine ,  Nikolaus Wenger ,  Silvestro Micera ,  Marco Capogrosso

IPC: A61N1/00 ,  A61N1/36 ,  A61N1/05 ,  A61B5/0488 ,  A61B5/00

Abstract: The present disclosure refers to systems for electrical neurostimulation of a spinal cord of a subject in need of nervous system function support. In one example, a system comprises a signal processing device configured to receive signals from the subject and operate signal-processing algorithms to elaborate stimulation parameter settings; one or more multi-electrode arrays suitable to cover a portion of the spinal cord of the subject; and an Implantable Pulse Generator (IPG) configured to receive the stimulation parameter settings from the signal processing device and simultaneously deliver independent current or voltage pulses to the one or more multiple electrode arrays, wherein the independent current or voltage pulses provide multipolar spatiotemporal stimulation of spinal circuits and/or dorsal roots. Such system advantageously enables effective control of nervous system functions in the subject by stimulating the spinal cord, such as the dorsal roots of the spinal cord, with spatiotemporal selectivity.

公开(公告)号：US10240688B2

公开(公告)日：2019-03-26

申请号：US15635225

申请日：2017-06-28

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Nadine Besse ,  Juan Josë Zarate ,  Samuel Rosset ,  Herbert Shea

IPC: F16K31/02 ,  F16K99/00 ,  F03G7/06

Abstract: An actuator device including a plurality of transducer actuators, and a common pneumatic actuation mechanism for shaping the plurality of transducer actuators, wherein each actuator of the plurality of transducer actuators includes a shape memory polymer membrane, an integrated stretchable heater, and a pressure interface to the common pneumatic actuation mechanism.

公开(公告)号：US10229337B2

公开(公告)日：2019-03-12

申请号：US15044841

申请日：2016-02-16

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Radhakrishna Shri Venkata Achanta

IPC: G06K9/34 ,  G06K9/46 ,  G06K9/62 ,  G06T7/11 ,  G06T7/187

Abstract: The present invention concerns a method of segmenting a media item comprising media elements. The method comprises: selecting a first seed media element for a first cluster of media elements, referred to hereinafter as a first adaptel; selecting a second seed media element, different from the first seed media element, for a second cluster of media elements, different from the media elements of the first adaptel, the second cluster being referred to hereinafter as a second adaptel; successively forming the first and second adaptels, starting from the first and second seed media elements, respectively, by allocating a first plurality of the media elements to the first adaptel, and then allocating a second plurality of the media elements to the second adaptel; and reallocating at least one media element of the first adaptel to the second adaptel if a dissimilarity measure between the at least one media element and the second adaptel is smaller than the dissimilarity measure between the at least one media element and the first adaptel. The second seed media element is selected from a set of the media elements neighboring the first adaptel.

公开(公告)号：US10228314B2

公开(公告)日：2019-03-12

申请号：US15508247

申请日：2015-09-01

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Conor Slater ,  Gaël Farine

IPC: G01N11/08 ,  G01N33/22

Abstract: Gas sensor (2) for measuring properties of a gas (1), including a gas viscosity sensor (4) comprising a gas interface portion (20) in contact with the gas (1) to be measured, and a measuring chamber system (15) comprising a measuring chamber (16), a first resistive passage (18) fluidically connecting the measuring chamber (16) to the gas interface portion (20), a pressure generator (25) configured to generate a change in pressure in the measuring chamber, and a pressure sensor (28) configured to measure a time dependent variation in pressure of gas in the measuring chamber, the time dependent variation of pressure in the measuring chamber due to flow of gas through the resistive passage being correlated to a viscosity of the gas. The gas viscosity sensor further comprises a reference chamber system (21) comprising a reference chamber and a second resistive passage (24) fluidically interconnecting the reference chamber (22) to the gas interface portion (20), the reference chamber (22) being coupled to the pressure sensor (28) of the measuring chamber such that the pressure sensor is configured to measure a differential pressure between a pressure in the measuring chamber and a pressure in the reference chamber.

公开(公告)号：US10217781B2

公开(公告)日：2019-02-26

申请号：US15633803

申请日：2017-06-27

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Mihai Adrian Ionescu ,  Nilay Dagtekin

IPC: H01L29/88 ,  H01L29/78 ,  H01L27/146 ,  H01L29/739

Abstract: A tunneling field effect transistor for light detection, including a p-type region connected to a source terminal, a n-type region connected to a drain terminal, an intrinsic region located between the p-type region and the n-type region to form a P-I junction or an N-I junction with the n-type region or the p-type region, respectively, a first insulating layer and a first gate electrode, the first gate electrode covering a portion of the intrinsic region on one side, and a second insulating layer and a second gate electrode, the second insulating layer and the second gate electrode covering an entire other side of the intrinsic region opposite to the one side, wherein an area of the intrinsic region that is not covered by the first gate electrode forms a non-gated intrinsic area configured for light absorption.