公开(公告)号：US6162817A

公开(公告)日：2000-12-19

申请号：US488227

申请日：2000-01-20

Applicant: Piyasena Hewawasam ,  Xi Chen ,  John E. Starrett, Jr.

Inventor： Piyasena Hewawasam ,  Xi Chen ,  John E. Starrett, Jr.

IPC: C07D271/10 ,  A61K31/4245 ,  A61P1/00 ,  A61P9/08 ,  A61P9/10 ,  A61P11/06 ,  A61P15/10 ,  A61P25/00 ,  A61P25/06 ,  A61P43/00 ,  C07D271/113 ,  C07O271/113

CPC classification number: C07D271/113

Abstract: The present invention provides novel carbamate oxadiazolone derivatives having the general formula ##STR1## wherein R.sup.1 and R.sup.2 are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of the large conductance calcium-activated potassium channels.

Abstract translation: 本发明提供新的具有通式的氨基甲酸酯恶二唑酮衍生物，其中R1和R2如本文所定义，或其无毒的药学上可接受的盐或溶剂合物，并且可用于治疗对大电导钙 - 活化钾通道。

公开(公告)号：US5703237A

公开(公告)日：1997-12-30

申请号：US634278

申请日：1996-04-18

Applicant: Xi Chen ,  Jan William Francis Wasley

Inventor： Xi Chen ,  Jan William Francis Wasley

IPC: C07D295/12 ,  A61K31/44 ,  A61K31/495 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/28 ,  A61P25/30 ,  A61P43/00 ,  C07D211/70 ,  C07D215/40 ,  C07D295/13 ,  C07D241/04 ,  C07D295/00

CPC classification number: C07D295/13 ,  C07D211/70 ,  C07D215/40

Abstract: Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 are the same or different and represent hydrogen, halogen, alkyl, alkoxy, hydroxy, cyano, nitro, trifluoromethyl, trifluoromethoxy; --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; or R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 independently represent --CONR'R", or --NR'R" where R' and R" independently represent hydrogen or C.sub.1 -C.sub.6 alkyl; R.sub.8 is hydrogen or lower alkyl; X represents an optionally substituted alkylene group; and Y represents a mono-, di- or trisubstituted cyclic amino group, which compounds are useful in treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parkinsonism and dystonia, and other disorders which respond to dopaminergic blockade such as substance abuse and obsessive compulsive disorders. Further, compounds of this invention may be useful in treating the extrapyramidal side effects associated with the use of conventional neuroleptic agents.

Abstract translation: 公开了下式的化合物或其药学上可接受的酸加成盐，其中：R 1，R 2，R 3，R 4，R 5，R 6和R 7相同或不同，表示氢，卤素，烷基，烷氧基，羟基 ，氰基，硝基，三氟甲基，三氟甲氧基; -O2CR'， - NHCOR'， - COR'，-SOmR'，其中R'是C1-C6烷基，其中m是0,1或2; 或R 1，R 2，R 3，R 4，R 5，R 6和R 7独立地表示-CONR'R“或-NR'R”，其中R'和R“独立地表示氢或C 1 -C 6烷基; R8是氢或低级烷基; X表示任选取代的亚烷基; 并且Y代表单取代或二取代或三取代的环状氨基，该化合物可用于治疗情感障碍如精神分裂症，抑郁症，阿尔茨海默氏病，运动障碍如帕金森综合征和肌张力障碍，以及其他对多巴胺能阻滞作用的疾病 作为物质滥用和强迫症。 此外，本发明的化合物可用于治疗与使用常规精神抑制剂相关的锥体束外副作用。

公开(公告)号：US5703083A

公开(公告)日：1997-12-30

申请号：US631152

申请日：1996-04-15

Applicant: Xi Chen ,  Jun Yuan

Inventor： Xi Chen ,  Jun Yuan

IPC: C07D295/14 ,  A61K31/44 ,  A61K31/47 ,  A61K31/472 ,  A61K31/495 ,  A61P25/00 ,  A61P25/14 ,  A61P25/18 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  A61P43/00 ,  C07D213/74 ,  C07D215/40 ,  C07D217/04 ,  C07D217/22 ,  C07D239/26 ,  C07D295/12 ,  C07D295/13 ,  C07D333/54

CPC classification number: C07D295/13 ,  C07D217/22

Abstract: Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addidon salts thereof wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 independently represent hydrogen, halogen, hydroxy, alkyl, alkoxy, amino, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, cyano, nitro, trifluoromethyl, or trifluoromethoxy; R.sub.8 is hydrogen or lower alkyl; X represents an optionally substituted alkylene group; and Y represents a mono-, di- or trisubsituted cyclic amino group which compounds are useful in the treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parldnsonism and dystonia, and other disorders which respond to dopaminergic blockade such as substance abuse and obsessive compulsive disorders. Further, compounds of this invention may be useful in treating the extrapyramidal side effects associated with the use of conventional neuroleptic agents.

Abstract translation: 公开了下式的化合物或其药学上可接受的酸加成盐，其中：R1，R2，R3，R4，R5，R6和R7独立地表示氢，卤素，羟基，烷基，烷氧基，氨基，氨基磺酰基 ，烷基氨基磺酰基，二烷基氨基磺酰基，氰基，硝基，三氟甲基或三氟甲氧基; R8是氢或低级烷基; X表示任选取代的亚烷基; 并且Y代表单，二或三取代的环状氨基，该化合物可用于治疗情感障碍如精神分裂症，抑郁症，阿尔茨海默病，运动障碍如帕尔德森氏症和肌张力障碍，以及其他对多巴胺能阻滞作用的其它病症 作为物质滥用和强迫症。 此外，本发明的化合物可用于治疗与使用常规精神抑制剂相关的锥体束外副作用。

公开(公告)号：US5659033A

公开(公告)日：1997-08-19

申请号：US527790

申请日：1995-09-13

Applicant: Jun Yuan ,  Xi Chen

Inventor： Jun Yuan ,  Xi Chen

IPC: C07D295/12 ,  A61K31/00 ,  A61K31/38 ,  A61K31/381 ,  A61K31/445 ,  A61K31/451 ,  A61K31/495 ,  A61K31/496 ,  A61P25/00 ,  A61P25/18 ,  A61P25/24 ,  A61P25/26 ,  A61P25/28 ,  A61P43/00 ,  C07D211/14 ,  C07D211/18 ,  C07D211/32 ,  C07D211/70 ,  C07D217/02 ,  C07D217/04 ,  C07D295/13 ,  C07D333/20 ,  C07D333/34

CPC classification number: C07D295/13 ,  C07D211/14 ,  C07D211/32 ,  C07D211/70 ,  C07D217/02 ,  C07C2103/18

Abstract: Disclosed are compounds of the formula ##STR1## or the pharmaceutically acceptable salts thereof wherein: G represents a group of the formula ##STR2## where R.sub.a and R.sub.b represent hydrogen, or organic or inorganic substituents;A is an optionally substituted alkylene;R.sub.1, R.sub.2, R.sub.3, R.sub.4 represent organic or inorganic substituents;R.sub.5 is hydrogen or lower alkyl;R.sub.6 and R.sub.7 independently represent hydrogen, lower alkyl; or together form a ring of 5-8 members;Z is nitrogen or carbon; andW is optionally substituted aryl or heteroaryl.Compounds of the present invention demonstrate high affinity and selectivity in binding to the D.sub.3 receptor subtype.

Abstract translation: 公开了式IMA的化合物或其药学上可接受的盐，其中：G表示式Ia的基团，其中R a和R b表示氢，或有机或无机取代基; A是任选取代的亚烷基; R1，R2，R3，R4代表有机或无机取代基; R5是氢或低级烷基; R6和R7独立地表示氢，低级烷基; 或一起组成5-8名成员的戒指; Z是氮或碳; W是任选取代的芳基或杂芳基。 本发明化合物在与D3受体亚型结合中表现出高亲和力和选择性。

公开(公告)号：US09959920B2

公开(公告)日：2018-05-01

申请号：US15453548

申请日：2017-03-08

Applicant: Junwei Liu ,  Kai Chang ,  Shuai-Hua Ji ,  Xi Chen ,  Liang Fu

Inventor： Junwei Liu ,  Kai Chang ,  Shuai-Hua Ji ,  Xi Chen ,  Liang Fu

IPC: G11C11/22 ,  H01L49/02 ,  H01L27/11507

CPC classification number: G11C11/221 ,  G11C11/22 ,  G11C11/2273 ,  G11C11/2275 ,  H01L27/11507 ,  H01L28/00 ,  H01L28/60

Abstract: A memory device includes a semiconductor layer with an in-plane polarization component switchable between a first direction and a second direction. A writing electrode is employed to apply a writing voltage to the semiconductor layer to change the in-plane polarization component between the first direction and the second direction. A reading electrode is employed to apply a reading voltage to the semiconductor layer to measure a tunneling current substantially perpendicular to the polarization direction of the in-plane polarization component. The directions of the reading voltage and the writing voltage are substantially perpendicular to each other. Therefore, the reading process is non-destructive. Thin films (e.g., one unit cell thick) of ferroelectric material can be used in the memory device to increase the miniaturization of the device.

公开(公告)号：US09767156B2

公开(公告)日：2017-09-19

申请号：US13701008

申请日：2012-08-30

Applicant: Xin-Jing Wang ,  Matthew Robert Scott ,  Xi Chen

Inventor： Xin-Jing Wang ,  Matthew Robert Scott ,  Xi Chen

IPC: G06F7/00 ,  G06F17/30 ,  G06F3/0484 ,  G06F17/27

CPC classification number: G06F17/3053 ,  G06F3/04842 ,  G06F17/276 ,  G06F17/30554 ,  G06F17/30864 ,  G06F17/30991

Abstract: A candidate for selection or insertion may be based on extracted candidate features and reference features. The candidate features may be scored and ranked while candidates may be removed from consideration based on criteria. The remaining candidates may be presented for selection and/or insertion.

公开(公告)号：US09103729B1

公开(公告)日：2015-08-11

申请号：US13249893

申请日：2011-09-30

Applicant: Ganping Ju ,  Jason L. Pressesky ,  Roy William Chantrell ,  Xiaowei Wu ,  Xi Chen ,  Xiaobin Zhu ,  Yingguo Peng

Inventor： Ganping Ju ,  Jason L. Pressesky ,  Roy William Chantrell ,  Xiaowei Wu ,  Xi Chen ,  Xiaobin Zhu ,  Yingguo Peng

IPC: G01R33/00 ,  G11B11/00 ,  G11B5/66 ,  G01K1/00 ,  G01K7/00 ,  H01L37/04 ,  G11B11/105 ,  G03G5/16 ,  H01F41/30 ,  H01L37/00 ,  G06F17/18

CPC classification number: G01N27/80 ,  G01K7/00 ,  G03G5/16 ,  G06F17/18 ,  G11B11/10591 ,  G11B2005/0021 ,  H01F41/304 ,  H01L37/00 ,  H01L37/04

Abstract: Determining a Curie temperature (Tc) distribution of a sample comprising magnetic material involves subjecting the sample to an electromagnetic field, heating the sample over a range of temperatures, generating a signal representative of a parameter of the sample that changes as a function of changing sample temperature while the sample is subjected to the electromagnetic field, and determining the Tc distribution of the sample using the generated signal and a multiplicity of predetermined parameters of the sample.

Abstract translation: 确定包含磁性材料的样品的居里温度（Tc）分布包括对样品进行电磁场，在一个温度范围内加热样品，产生代表随变化样品变化的样品参数的信号 温度，同时样品经受电磁场，并使用生成的信号和样本的多个预定参数确定样品的Tc分布。

公开(公告)号：US09090861B2

公开(公告)日：2015-07-28

申请号：US12228897

申请日：2008-08-15

Applicant: Xi Chen ,  Swee-How Seow ,  Tobias Fütterer

Inventor： Xi Chen ,  Swee-How Seow ,  Tobias Fütterer

IPC: C11D17/00 ,  C11D9/26 ,  C11D10/04 ,  C11D1/52 ,  C11D1/66 ,  C11D1/72

CPC classification number: C11D17/0026 ,  C11D1/52 ,  C11D1/667 ,  C11D1/72 ,  C11D9/26 ,  C11D9/267 ,  C11D10/04 ,  C11D10/045 ,  C11D10/047

Abstract: A structured soap composition contains, based on 100 parts by weight of said composition, (i) from greater than 0 to about 27 parts by weight of a neutralized fatty acid, (ii) from greater than 0 to about 18 parts by weight of one or more structurant selected from alkanolamide surfactants, fatty alcohols, alkoxylated fatty alcohols, fatty acids, and fatty acid esters, (iii) from 0 to about 15 parts by weight of one or more compounds selected from amphoteric surfactants and zwitterionic surfactants, provided that the total amount of components (i), (ii), and (iii) is greater than or equal to 5 parts by weight, (iv) an amount of electrolyte effective to, in combination with components (i), (ii), and (iii) provide a structured soap composition having an opaque visual appearance and exhibiting a yield strength of greater than 0 Pascals, and (v) water.

公开(公告)号：US20150199332A1

公开(公告)日：2015-07-16

申请号：US14423950

申请日：2012-08-31

Applicant: Mu Li ,  Xi Chen

Inventor： Mu Li ,  Xi Chen

IPC: G06F17/27 ,  G06F17/30 ,  H04L29/08

CPC classification number: G06F16/9574 ,  G06F3/018 ,  G06F3/0237 ,  G06F17/276 ,  H04L67/2857

Abstract: Some examples may include generating a browsing history language model based on browsing history information. Further, some implementations may include predicting and presenting a non-Latin character string based at least in part on the browsing history language model, such as in response to receiving a Latin character string via an input method editor interface.

Abstract translation: 一些示例可以包括基于浏览历史信息生成浏览历史语言模型。 此外，一些实现可以包括至少部分地基于浏览历史语言模型来预测和呈现非拉丁字符串，诸如响应于经由输入方法编辑器界面接收拉丁字符串。

公开(公告)号：US20140123750A1

公开(公告)日：2014-05-08

申请号：US14124598

申请日：2011-11-29

Applicant: Jianming Liu ,  Xiangzhen Li ,  Yan Zhen ,  Xi Chen ,  Lingkang Zeng ,  Qinghai Ou ,  Qingsu He

Inventor： Jianming Liu ,  Xiangzhen Li ,  Yan Zhen ,  Xi Chen ,  Lingkang Zeng ,  Qinghai Ou ,  Qingsu He

IPC: G01W1/06 ,  G01N17/00

CPC classification number: G01W1/06 ,  G01N17/00 ,  G01W1/02 ,  G01W1/14 ,  H02J13/0075 ,  Y02E60/74 ,  Y02E60/7853 ,  Y04S10/30 ,  Y04S10/54 ,  Y04S40/126

Abstract: A system for monitoring a power transmission line of a power grid, including a first comprehensive sensor (402, 502) disposed at the intermediate position of a power transmission line between two towers including an altimeter, a first acceleration sensor, a temperature and humidity sensor and a rainfall sensor; a second comprehensive sensor (404, 504) disposed at the cable connector of the power transmission line including a leakage current sensor, a tension sensor and a wind speed and direction sensor; and a second acceleration sensor (406, 506) disposed at the intermediate position of the power transmission line between the cable connector of the power transmission line and the first comprehensive sensor (402, 502). A method for monitoring a power transmission line of a power grid, including a step of monitoring the sag condition, wind yaw angle, motion and position tracking, flutter conditions, breeze vibration level, fatigue life and icing situation of a power transmission line. The method and system for monitoring a power transmission line of a power grid effectively prevent and reduce incidents of the power transmission line of the power grid based on sensor multi-dimensional sensing technology combined with the advantages of wireless sensor network technology.

Abstract translation: 一种用于监测电力网的输电线路的系统，包括设置在两个塔之间的输电线路的中间位置处的第一综合传感器（402,502），包括高度计，第一加速度传感器，温度和湿度传感器 和降雨传感器; 设置在电力传输线的电缆连接器处的第二综合传感器（404,504），包括泄漏电流传感器，张力传感器和风速和方向传感器; 以及第二加速度传感器（406,506），其设置在所述输电线路的电缆连接器与所述第一综合传感器（402,502）之间的所述输电线路的中间位置。 一种用于监测电网的输电线路的方法，包括监测输电线路的下垂条件，风偏角，运动和位置跟踪，颤振条件，微风振动水平，疲劳寿命和结冰情况的步骤。 基于传感器多维感知技术，结合无线传感器网络技术的优势，对电网输电线路进行监控的方法和系统有效地防止和减少了电网输电线路的事故发生。