公开(公告)号：US20120251592A1

公开(公告)日：2012-10-04

申请号：US13472346

申请日：2012-05-15

Applicant: Jennifer A. Neff ,  Joseph McGuire ,  Pranav R. Joshi

Inventor： Jennifer A. Neff ,  Joseph McGuire ,  Pranav R. Joshi

IPC: A01N25/10 ,  B32B1/02 ,  A01N37/46

CPC classification number: A01N25/10 ,  A01N25/34 ,  A01N63/02 ,  A23L3/3463 ,  A61K47/48215 ,  A61K47/48992 ,  A61K47/60 ,  A61K47/6957 ,  A61L2/232 ,  C08G65/3348 ,  C08G2650/58 ,  C08K9/08 ,  C08K2201/013 ,  C08L71/02 ,  C08L2205/05 ,  Y10T428/1352 ,  Y10T428/1376 ,  A01N43/90 ,  A01N2300/00 ,  C08L2666/02 ,  A01N37/46

Abstract: The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.

Abstract translation: 本发明基于以下认识：已知的抗微生物化合物，例如乳链菌肽或其它拉坦生物，可以通过将肽与嵌段聚合物如F108或端基活化聚合物连接形成长效的抗微生物表面涂层 （EGAP），以形成柔性系链和/或捕获肽。 捕获的肽通过早期释放释放而提供抗微生物作用，而束缚肽提供更持久的抗微生物保护。 可以使用含抗菌肽的嵌段共聚物来制备抗微生物凝胶和泡沫。

公开(公告)号：US20100249297A1

公开(公告)日：2010-09-30

申请号：US12676084

申请日：2008-09-03

Applicant: Jens Christoph Thies ,  Pascal Jozef Paul Buskens

Inventor： Jens Christoph Thies ,  Pascal Jozef Paul Buskens

IPC: C08K5/5415

CPC classification number: C08K3/22 ,  C08J3/128 ,  C08J2321/02 ,  C08K2201/013

Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising (a) cationic core material comprising latex; and (b) shell material comprising metal oxide.

Abstract translation: 本发明提供包含核 - 壳纳米颗粒的组合物，所述纳米颗粒包含（a）包含胶乳的阳离子核心材料; 和（b）包含金属氧化物的壳材料。

公开(公告)号：US20100009001A1

公开(公告)日：2010-01-14

申请号：US12438591

申请日：2007-09-05

Applicant: Steven Armes ,  Jian-Jun Yuan

Inventor： Steven Armes ,  Jian-Jun Yuan

IPC: A61K9/14 ,  A61P43/00

CPC classification number: A61K9/5089 ,  A61K9/501 ,  C08K3/36 ,  C08K9/00 ,  C08K9/02 ,  C08K9/12 ,  C08K2201/011 ,  C08K2201/013 ,  C08L53/00 ,  C08L2207/53 ,  C09D7/70 ,  G02B1/111 ,  Y10T428/254 ,  Y10T428/2998

Abstract: The invention provides a composition comprising core-shell nanoparticles, the nanoparticles comprising (a) cationic core material comprising polymer; and (b) a shell material comprising silica. Preferred core materials comprise diblock copolymer micelles comprising one block of dialkylaminoethyl methacrylate units which are partially or fully quaternised and one block of dialkylaminoethyl methacrylate units that remain non-quaternised. The invention also provides a method for the preparation of the said composition, the method involving (a) preparing a cationic core material comprising polymer; and (b) coating the core material with a shell comprising silica by treating the polymer with a silica precursor under ambient conditions. The invention also envisages a composition comprising core-shell nanoparticles which is adapted to facilitate controlled delivery of at least one active agent into a system in response to controlled changes in the pH of the system.

Abstract translation: 本发明提供包含核 - 壳纳米颗粒的组合物，所述纳米颗粒包含（a）包含聚合物的阳离子核心材料; 和（b）包含二氧化硅的壳材料。 优选的核心材料包括二嵌段共聚物胶束，其包含部分或全部季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元和一个保持非季铵化的一个二烷基氨基乙基甲基丙烯酸酯单元。 本发明还提供了一种制备所述组合物的方法，所述方法包括（a）制备包含聚合物的阳离子核心材料; 和（b）在环境条件下用二氧化硅前体处理聚合物，用包含二氧化硅的壳涂覆芯材。 本发明还设想包含核 - 壳纳米颗粒的组合物，其适于响应于系统的pH的受控变化而促进至少一种活性剂被控制递送到系统中。

公开(公告)号：US20090246280A1

公开(公告)日：2009-10-01

申请号：US12227877

申请日：2007-05-30

Applicant: Kenji Yamashita

Inventor： Kenji Yamashita

IPC: A61K33/06 ,  C08J3/12 ,  A61P31/04 ,  A61K9/14 ,  A61P31/10 ,  B01J20/26

CPC classification number: C08L75/00 ,  A01N59/06 ,  B01J20/0248 ,  B01J20/0281 ,  B01J20/0288 ,  B01J20/08 ,  B01J20/24 ,  B01J20/261 ,  B01J20/262 ,  B01J20/265 ,  B01J20/267 ,  C08F8/44 ,  C08H1/06 ,  C08J3/12 ,  C08J2329/04 ,  C08J2389/04 ,  C08K3/24 ,  C08K3/30 ,  C08K5/1515 ,  C08K7/20 ,  C08K9/08 ,  C08K2201/013 ,  C08L1/286 ,  C08L75/04 ,  C08L89/04 ,  C08L89/06 ,  Y10T428/2982 ,  A01N25/10 ,  A01N25/08 ,  A01N25/12 ,  A01N2300/00 ,  C08F16/06 ,  C08L2666/26

Abstract: An aluminum salt-containing resin powder of the present invention includes: at lest one matrix resin component selected from regenerated collagen, polyvinyl alcohol and carboxymethyl cellulose; and an aluminum salt. The aluminum salt is chemically bonded to the matrix resin component, and the resultant is powdered. A resin composition of the present invention includes 0.1 wt % or more and 80 wt % or less of the aluminum salt-containing resin powder and 20 wt % or more and 99.9 wt % or less of a resin other than the aluminum salt-containing resin. Thus, the present invention provides an aluminum salt-containing resin powder having a high phosphorus adsorption property, a high antibacterial property and a high antifungal property, and a resin composition containing the aluminum salt-containing resin powder.

Abstract translation: 本发明的含铝盐树脂粉末包括：至少一种选自再生胶原，聚乙烯醇和羧甲基纤维素的基质树脂组分; 和铝盐。 铝盐与基质树脂组分化学键合，粉末形成。 本发明的树脂组合物含有0.1重量％以上且80重量％以下的含铝盐树脂粉末和20重量％以上且99.9重量％以下的除含铝盐树脂以外的树脂 。 因此，本发明提供了具有高磷吸附性，高抗菌性和高抗真菌性的含铝盐树脂粉末和含有含铝盐的树脂粉末的树脂组合物。

公开(公告)号：US20090022888A1

公开(公告)日：2009-01-22

申请号：US12171593

申请日：2008-07-11

Applicant: Jennifer A. Neff ,  Joseph McGuire ,  Pranav R. Joshi

Inventor： Jennifer A. Neff ,  Joseph McGuire ,  Pranav R. Joshi

IPC: B05D1/18 ,  C08F279/02 ,  C08F283/10 ,  C08F283/00

CPC classification number: A01N25/10 ,  A01N25/34 ,  A01N63/02 ,  A23L3/3463 ,  A61K47/48215 ,  A61K47/48992 ,  A61K47/60 ,  A61K47/6957 ,  A61L2/232 ,  C08G65/3348 ,  C08G2650/58 ,  C08K9/08 ,  C08K2201/013 ,  C08L71/02 ,  C08L2205/05 ,  Y10T428/1352 ,  Y10T428/1376 ,  A01N43/90 ,  A01N2300/00 ,  C08L2666/02 ,  A01N37/46

Abstract: The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.

Abstract translation: 本发明基于认识到已知的抗微生物化合物，例如乳链菌肽或其他拉坦生物，可以通过将肽与嵌段聚合物如F108或端基连接而形成长效的抗微生物表面涂层 活化聚合物（EGAP），以形成柔性系链和/或捕获肽。 捕获的肽通过早期释放释放而提供抗微生物作用，而束缚肽提供更持久的抗微生物保护。 可以使用含抗菌肽的嵌段共聚物来制备抗微生物凝胶和泡沫。

公开(公告)号：US20060264523A1

公开(公告)日：2006-11-23

申请号：US10546299

申请日：2004-02-18

Applicant: Min-hee Lee ,  Bong-keun Lee ,  Ki-deog Choi

Inventor： Min-hee Lee ,  Bong-keun Lee ,  Ki-deog Choi

IPC: C08J9/00

CPC classification number: C08J9/0066 ,  B82Y30/00 ,  C08J9/0071 ,  C08J2327/06 ,  C08K3/346 ,  C08K2201/011 ,  C08K2201/013 ,  C08L27/06

Abstract: The present invention relates to the foams of the polyvinyl chloride nanocomposites comprising of polyvinyl chloride, layered inorganic compounds, and foaming agents. They are effective in that they have superior mechanical strength and non-flammability even with a low specific gravity; demostrates a high foaming efficiency even with a small amount of a foaming agent; and have an even microcellular structure.

Abstract translation: 本发明涉及包含聚氯乙烯，层状无机化合物和发泡剂的聚氯乙烯纳米复合材料的泡沫体。 它们是有效的，因为它们即使具有低比重也具有优异的机械强度和不可燃性; 即使使用少量的发泡剂也能发挥高发泡效率; 并具有均匀的微细胞结构。

公开(公告)号：US07060241B2

公开(公告)日：2006-06-13

申请号：US10105623

申请日：2002-03-26

Applicant: Paul J. Glatkowski

Inventor： Paul J. Glatkowski

IPC: D01F9/12

CPC classification number: B82Y30/00 ,  B82Y10/00 ,  C08J5/18 ,  C08J2379/08 ,  C08K3/041 ,  C08K2201/013 ,  C09D5/24 ,  C09D179/08 ,  C09D185/02 ,  H01B1/24 ,  Y10T428/24994 ,  Y10T428/249942 ,  Y10T428/249945

Abstract: An electrically conductive film is disclosed. According to one embodiment of the present invention, the film includes a plurality of single-walled nanotubes having a particular diameter. The disclosed film demonstrates excellent conductivity and transparency. Methods of preparing the film as well as methods of its use are also disclosed herein.

公开(公告)号：US20060121270A1

公开(公告)日：2006-06-08

申请号：US11334574

申请日：2006-01-19

Applicant: Osamu Kazeto

Inventor： Osamu Kazeto

IPC: B32B5/16 ,  B32B27/00

CPC classification number: C08K5/09 ,  C08K3/01 ,  C08K2201/013 ,  C09D5/03 ,  C09D129/02 ,  Y10T428/25 ,  Y10T428/254 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2993 ,  Y10T428/2998 ,  Y10T428/31692 ,  C08L29/02 ,  C08L2666/54 ,  C08L2666/28

Abstract: An ethylene-vinyl alcohol copolymer (EVOH) composition comprises 100 parts by weight of a powder (A) having a particle size of from 22 to 850 μm of an ethylene-vinyl alcohol copolymer (a) which has an ethylene content of from 2 to 60 mol % and has a degree of saponification greater than 95%, and from 0.0001 to 2 parts by weight of inorganic particles (B) having primary particles with a mean particle size of from 1 to 100 nm. The EVOH powder coating composition of the present invention forms a coating film having good uniformity when applied to a substrate as powder coating, even when it contains 1 part by weight or more water relative to 100 parts by weight of EVOH resin.

公开(公告)号：US20050081754A1

公开(公告)日：2005-04-21

申请号：US10962604

申请日：2004-10-13

Applicant: Osamu Kazeto

Inventor： Osamu Kazeto

IPC: C08F216/06 ,  C08K3/00 ,  C08K5/09 ,  C09D129/02 ,  C04B14/02

CPC classification number: C08K5/09 ,  C08K3/01 ,  C08K2201/013 ,  C09D5/03 ,  C09D129/02 ,  Y10T428/25 ,  Y10T428/254 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2993 ,  Y10T428/2998 ,  Y10T428/31692 ,  C08L29/02 ,  C08L2666/54 ,  C08L2666/28

Abstract: An ethylene-vinyl alcohol copolymer (EVOH) composition comprises 100 parts by weight of a powder (A) having a particle size of from 22 to 850 μm of an ethylene-vinyl alcohol copolymer (a) which has an ethylene content of from 2 to 60 mol % and has a degree of saponification greater than 95%, and from 0.0001 to 2 parts by weight of inorganic particles (B) having primary particles with a mean particle size of from 1 to 100 nm. The EVOH powder coating composition of the present invention forms a coating film having good uniformity when applied to a substrate as powder coating, even when it contains 1 part by weight or more water relative to 100 parts by weight of EVOH resin.

Abstract translation: 乙烯 - 乙烯醇共聚物（EVOH）组合物包含100重量份的乙烯 - 乙烯醇共聚物（a）的粒径为22〜850μm的粉末（A），其乙烯含量为2〜 60摩尔％，皂化度大于95％，和0.0001〜2重量份具有平均粒径为1〜100nm的一次粒子的无机粒子（B）。 本发明的EVOH粉末涂料组合物即使当相对于100重量份的EVOH树脂含有1重量份以上的水分时，也可以形成作为粉末涂料涂布在基材上的均匀性均匀的涂膜。

公开(公告)号：US06583199B2

公开(公告)日：2003-06-24

申请号：US09970138

申请日：2001-10-03

Applicant: Theodore B. Brother ,  Edward J. Ellis

Inventor： Theodore B. Brother ,  Edward J. Ellis

IPC: C08K509

CPC classification number: C08K3/26 ,  C08K2201/013 ,  Y10T428/1352

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises hollow coated micro particles cohered to a mass by a combination of a carboxylic acid bonding agent and a hydrophobic fluid. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical or vehicular cushions, positioning devices, mattresses impact protective padding and the like.

Abstract translation: 描述了用于弹性贴合垫，靠垫，耐冲击性填料等的改进材料。 该材料包括通过羧酸粘合剂和疏水性流体的组合粘结到物料上的中空涂覆的微粒子。 该材料可用于为服装，运动器材，假肢装置，手术或车辆垫子，定位装置，床垫冲击保护垫等提供低重量轮廓符合弹性衬垫。