Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof

    公开(公告)号:US11453736B2

    公开(公告)日:2022-09-27

    申请号:US17038349

    申请日:2020-09-30

    Applicant: Alcon Inc.

    Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

    PROCESS FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON

    公开(公告)号:US20220299796A1

    公开(公告)日:2022-09-22

    申请号:US17834191

    申请日:2022-06-07

    Applicant: Alcon Inc.

    Abstract: The invention is related to a method for producing soft contact lenses comprises a silicone hydrogel lens body and a composite coating thereon. The composite coating comprises: a plasma base coating which is chemically-attached directly onto the surface of the silicone hydrogel contact lens and functions as a fail-proof measure for ensuring the hydrophobic silicone hydrogel lens material to be shielded from any exposure to ocular environments even after at least 30 days of daily uses including daily waring and daily cleaning/disinfecting; and a relatively-durable lubricious hydrogel top coating for ensuring wearing comfort. A method of the invention comprises forming a plasma-reactive hydrophilic polymer hybrid base coating having reactive functional groups on a silicone hydrogel contact lens and heating the silicone hydrogel contact lens with the hybrid base coating in an aqueous solution of a water-soluble and thermally crosslinkable hydrophilic polymeric material to form a stable lubricious hydrogel coating thereon. This method has a minimized adverse impact on the mechanical properties of silicone hydrogel lens body.

    Angle adjustment system
    163.
    发明授权

    公开(公告)号:US11448854B2

    公开(公告)日:2022-09-20

    申请号:US16790970

    申请日:2020-02-14

    Applicant: Alcon Inc.

    Abstract: Certain aspects of the present disclosure provide to angle adjustment systems using one or more spring arrangements. In certain aspects, an angle adjustment system comprises a component and a first spring arrangement coupled to the component, wherein the first spring arrangement comprises at least three spring elements. Further, the first spring arrangement is configured to allow the component to rotate around a first axis of rotation and prevent a first translational movement of the component with respect to the first axis of rotation.

    Intraocular lens injector
    165.
    发明授权

    公开(公告)号:US11439499B2

    公开(公告)日:2022-09-13

    申请号:US16507393

    申请日:2019-07-10

    Applicant: Alcon Inc.

    Abstract: An intraocular lens (IOL) injectors and associated methods are described. The IOL injectors may include a collapsible portion configured to reduce the length of the IOL injector when the collapsible portion is altered from an uncollapsed configuration to a collapsed configuration. In some instances, an IOL may be advanced from a storage location to a dwell location when the collapsible portion is altered from the uncollapsed configuration to the collapsed configuration. The IOL injectors may also include a combination push and screw drive.

    METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES

    公开(公告)号:US20220281193A1

    公开(公告)日:2022-09-08

    申请号:US17688022

    申请日:2022-03-07

    Applicant: Alcon Inc.

    Abstract: Described herein is a method for producing a contact lens comprising a central zone that has a diameter of about 13 mm or less, is concentric with the central axis of the contact lens, and possesses at least one photo functionality. The method comprises: applying a first polymerizable fluid composition containing at least one photochemically functional compound on a central portion of the molding surface of a female mold half to form a circular layer; partially curing, in situ, the circular layer in the female mold half; dispensing a second polymerizable fluid composition over the partially-cured circular layer on the molding surface of the female mold half; and a step of curing the second polymerizable fluid composition and the partially-cured circular layer immersed therein in the mold cavity formed between the the molding surfaces of the female mold half and a male mold half.

    Aligning multi-wavelength laser beams with cores of a multi-core fiber

    公开(公告)号:US11432963B2

    公开(公告)日:2022-09-06

    申请号:US16884262

    申请日:2020-05-27

    Applicant: Alcon Inc.

    Abstract: Particular embodiments disclosed herein provide a surgical laser system comprising first laser source configured to emit a first laser beam with a first wavelength and a second laser source configured to emit a second laser beam with a second wavelength. The surgical laser system further comprises a first diffraction optical element (DOE) tuned to the first wavelength and a second DOE tuned to the second wavelength, wherein the first DOE is configured to diffract the first laser beam into one or more first diffracted beams at a diffraction angle and the second DOE is configured to diffract the second laser beam into one or more second diffracted beams at the same diffraction angle. The surgical laser system further comprises one or more beam splitters configured to reflect the one or more first diffracted beams and the one or more second diffracted beams onto a lens.

    Method for verifying the accurate mounting of molding inserts to a tooling plate of an injection-molding apparatus for molding ophthalmic lens molds

    公开(公告)号:US20220274307A1

    公开(公告)日:2022-09-01

    申请号:US17652729

    申请日:2022-02-28

    Applicant: ALCON INC.

    Abstract: A method for verifying whether a molding insert (1a, 1b) is accurately mounted to a tooling plate (2a, 2b) comprises the steps of: a) providing a confocal sensor (3a, 3b); b) arranging the confocal sensor (3a, 3b) such that a confocal sensor reference plane (32a, 32b) as well as a tooling plate reference plane (22a, 22b) are normal to a mounting axis (21a, 21b) of the tooling plate and spaced from each other by a predetermined first distance (d1, e1); c) measuring a second distance (d2, e2) between the confocal sensor reference plane (32a, 32b) and a central impingement location (11a, 11b) on a molding surface (12a, 12b) of the molding insert (1a, 1b); d) based on the measured second distance (d2, e2) as well as based on the predetermined first distance (d1, e1), determining a third distance (d3, e3) of the central impingement location (11a, 11b) relative to the tooling plate reference plane (22a, 22b); e) comparing the third distance (d3, e3) with a predetermined target distance, and f) determining that the molding insert (1a, 1b) is accurately mounted to the tooling plate (2a, 2b) if the difference between the third distance (d3, e3) and the predetermined target distance is less than a threshold difference.

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