公开(公告)号：US4745232A

公开(公告)日：1988-05-17

申请号：US1243

申请日：1987-01-07

Applicant: Robert J. Schmitt ,  David S. Ross ,  James F. Wolfe

Inventor： Robert J. Schmitt ,  David S. Ross ,  James F. Wolfe

IPC: C07C201/00 ,  C07C67/00 ,  C07C201/08 ,  C07C205/20 ,  C07C205/23 ,  C07C79/28

CPC classification number: C07C201/08

Abstract: A method of nitrating resorcinol which is selective for the production of the 4,6-dinitro resorcinal isomer. A resorcinol-based starting material is admixed with a nitrating solution from which substantially all nitrogen dioxide and nitrous has been removed. The nitrating solution contains white fuming nitric acid, a nitrosonium ion control agent such as urea, and, optionally, concentrated sulfuric acid. The 4,6-dinitroresorcinal isomer is provided in yields of about 65-85% with minimal production of undesirable side products.

Abstract translation: 一种硝化间苯二酚的方法，间苯二酚对于生产4,6-二硝基间苯二酚异构体是有选择性的。 将基于间苯二酚的原料与硝化溶液混合，从其中除去基本上所有的二氧化氮和亚硝酸。 硝化溶液含有白色发烟硝酸，硝基鎓离子控制剂如尿素，以及任选的浓硫酸。 提供的4,6-二硝基间苯二酚异构体的产率约为65-85％，同时产生不希望的副产物。

公开(公告)号：US4727083A

公开(公告)日：1988-02-23

申请号：US911867

申请日：1986-09-26

Applicant: Junya Takahashi ,  Hiroshi Noguchi ,  Yukio Oguri ,  Shigeo Yamamoto ,  Toshiro Kato ,  Katsuzo Kamoshita

Inventor： Junya Takahashi ,  Hiroshi Noguchi ,  Yukio Oguri ,  Shigeo Yamamoto ,  Toshiro Kato ,  Katsuzo Kamoshita

IPC: A01N33/22 ,  C07C67/00 ,  C07C201/00 ,  C07C205/37 ,  A01N33/18 ,  A01N37/18 ,  A01N43/52 ,  A01N43/76

CPC classification number: A01N33/22 ,  C07C205/37

Abstract: A fungicidal composition which comprises as an active ingredient a compound of the formula: ##STR1## wherein X is a halogen atom, a C.sub.1 -C.sub.3 alkyl group or a C.sub.1 -C.sub.3 alkoxy group, and an inert carrier or diluent.

Abstract translation: 一种杀真菌组合物，其包含下式化合物作为活性成分：其中X为卤素原子，C1-C3烷基或C1-C3烷氧基，惰性载体或稀释剂。

公开(公告)号：US4709078A

公开(公告)日：1987-11-24

申请号：US865406

申请日：1986-05-21

Applicant: Ulrich Schirmer ,  Stefan Karbach ,  Ernst-Heinrich Pommer ,  Eberhard Ammermann ,  Wolfgang Steglich ,  Barbara A. M. Schwalge ,  Timm Anke

Inventor： Ulrich Schirmer ,  Stefan Karbach ,  Ernst-Heinrich Pommer ,  Eberhard Ammermann ,  Wolfgang Steglich ,  Barbara A. M. Schwalge ,  Timm Anke

IPC: C07C69/734 ,  A01N37/34 ,  A01N37/38 ,  A01N37/48 ,  A01N41/02 ,  A01N41/04 ,  A01N41/06 ,  A01N41/10 ,  A01N47/28 ,  A01N47/48 ,  C07C67/00 ,  C07C201/00 ,  C07C205/35 ,  C07C205/56 ,  C07C213/00 ,  C07C217/76 ,  C07C233/25 ,  C07C233/63 ,  C07C233/75 ,  C07C235/42 ,  C07C235/56 ,  C07C239/00 ,  C07C253/00 ,  C07C255/54 ,  C07C255/57 ,  C07C271/28 ,  C07C275/32 ,  C07C301/00 ,  C07C309/42 ,  C07C309/63 ,  C07C309/66 ,  C07C309/75 ,  C07C311/16 ,  C07C311/29 ,  C07C313/00 ,  C07C317/22 ,  C07C323/19 ,  C07C325/00 ,  C07C331/10 ,  C07C69/76

CPC classification number: C07C255/00 ,  A01N37/38 ,  C07C205/35 ,  C07C205/56 ,  C07C309/66 ,  C07C311/16 ,  C07C317/22 ,  C07C323/19 ,  C07C331/10

Abstract: Acrylates of the general formula ##STR1## wherein R.sup.1 and R.sup.2 independently of one another are each C.sub.1 -C.sub.8 -alkyl, X is hydrogen, C.sub.1 -C.sub.4 -alkyl, halogen, C.sub.1 -C.sub.4 -alkoxy, haloalkyl, cyano or nitro, W is unsubstituted or alkyl-substituted, saturated or unsaturated C.sub.1 -C.sub.10 -alkylene, Y is hydrogen, alkyl, haloalkyl, alkoxyalkyl, cycloalkyl, aralkyl, aryl, aryloxy, halogen, an unsubstituted or substituted C.sub.4 H.sub.4 chain fused to the benzene radical, alkoxy, haloalkoxy, alkylthio, thiocyanato, cyano, NO.sub.2, aralkyloxy, ##STR2## and R' and R" independently of one another are each hydrogen, alkyl, alkoxy, alkylthio or cycloalkyl or are each phenyl which is unsubstituted or substituted by alkyl, halogen or alkoxy, and n is from 1 to 4, and fungicides containing them.

Abstract translation: 其中R 1和R 2各自独立地为C 1 -C 8 - 烷基，X为氢，C 1 -C 4 - 烷基，卤素，C 1 -C 4 - 烷氧基，卤代烷基，氰基或硝基的通式为“IMAGE”的丙烯酸酯，W为 未取代的或烷基取代的饱和或不饱和的C 1 -C 10 - 亚烷基，Y是氢，烷基，卤代烷基，烷氧基烷基，环烷基，芳烷基，芳基，芳氧基，卤素，与苯基稠合的未取代或取代的C4H4链，烷氧基，卤代烷氧基 ，烷硫基，氰硫基，氰基，NO 2，芳烷基氧基，R'和R“彼此独立地分别是氢，烷基，烷氧基，烷硫基或环烷基，或各自是未取代或取代的苯基 烷基，卤素或烷氧基，n为1至4，含有它们的杀真菌剂。

公开(公告)号：US4705797A

公开(公告)日：1987-11-10

申请号：US701672

申请日：1985-02-14

Applicant: Dante Nardi ,  Amedeo Leonardi ,  Gabriele Graziani ,  Giorgio Bianchi

Inventor： Dante Nardi ,  Amedeo Leonardi ,  Gabriele Graziani ,  Giorgio Bianchi

IPC: A61K31/41 ,  A61K31/435 ,  A61K31/44 ,  A61K31/455 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  C07C67/00 ,  C07C201/00 ,  C07C205/56 ,  C07D211/90 ,  C07D413/04 ,  C07D413/14

CPC classification number: C07D413/04 ,  C07C205/56 ,  C07D211/90

Abstract: Novel antihypertensive and coronary dilating asymmetric diesters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid (or the stereoisomers or pharmaceutically acceptable acid addition salts thereof) have the general formula (I): ##STR1## wherein Ph is phenyl, Ar is 2-nitrophenyl, 3-nitrophenyl, 2,3-dichlorophenyl or benzofurazan-4-yl, A is a straight or branched chain alkylene radical having from 2 to 6 carbon atoms, R is a straight or branched chain alkyl radical having from 1 to 6 carbon atoms, optionally mono-substituted by an alkoxy substituent having from 1 to 6 carbon atoms, R.sub.1 is hydrogen, hydroxy or an alkyl radical having from 1 to 4 carbon atoms, and R.sub.2 is hydrogen or methyl. The subject diesters are facilely prepared from the aldehydes ArCHO and esters of acetoacetic and 3-aminocrotonic acids.

Abstract translation: 1,4-二氢-2,6-二甲基 - 吡啶-3,5-二羧酸（或其立体异构体或其药学上可接受的酸加成盐）的新型抗高血压和冠状动脉扩张不对称二酯具有通式（I）：（I）其中Ph是苯基，Ar是2-硝基苯基，3-硝基苯基，2,3-二氯苯基或苯并呋咱-4-基，A是具有2至6个碳原子的直链或支链亚烷基，R是 具有1至6个碳原子的直链或支链烷基，任选被具有1至6个碳原子的烷氧基取代基单取代，R 1是氢，羟基或具有1至4个碳原子的烷基，R 2 是氢或甲基。 受试二酯由醛ArCHO和乙酰乙酸和3-氨基巴豆酸的酯容易地制备。

公开(公告)号：US4695656A

公开(公告)日：1987-09-22

申请号：US846011

申请日：1986-03-31

Applicant: Kuno Reh ,  Friedrich Schophoff

Inventor： Kuno Reh ,  Friedrich Schophoff

IPC: C07C67/00 ,  C07C201/00 ,  C07C201/12 ,  C07C205/37 ,  C07D307/12 ,  C07D307/02

CPC classification number: C07D307/12 ,  C07C201/12

Abstract: 2,4-Dinitrophenyl ethers are prepared by reacting a 2,4-dinitrochlorobenzene or 2,4-dinitrobromobenzene with an alkali metal alcoholate in a non-polar, inert solvent, at a temperature from -25.degree. C. to 50.degree. C.

Abstract translation: 2,4-二硝基苯醚通过在非极性惰性溶剂中，在-25℃至50℃的温度下使2,4-二硝基氯苯或2,4-二硝基溴苯与碱金属醇盐反应来制备。

公开(公告)号：US4670608A

公开(公告)日：1987-06-02

申请号：US826710

申请日：1986-03-19

Applicant: Christian Paetz ,  Karlfried Wedemeyer

Inventor： Christian Paetz ,  Karlfried Wedemeyer

IPC: C07B61/00 ,  B01J27/00 ,  C07C67/00 ,  C07C201/00 ,  C07C201/12 ,  C07C205/12 ,  C07C205/26 ,  C07C215/76 ,  G03C7/34 ,  C07C79/32

CPC classification number: G03C7/346 ,  C07C201/12 ,  C07C201/16 ,  C07C213/02

Abstract: 2,4-Dichloro-3-alkyl-6-nitrophenols are prepared by chlorinating, with chlorine in the presence of a catalyst, 1-alkyl-4-nitrobenzenes having a C.sub.2 -C.sub.8 -alkyl radical until the content of trichloroalkylnitrobenzenes is at least 60% by weight in the chlorination mixture, removing the catalyst from the chlorination mixture, then hydrolyzing the chlorination mixture, removing the precipitated reaction product, and treating it with an aqueous inorganic acid. The 2,4-dichloro-3-alkyl-6-nitrophenols are new.

Abstract translation: 2,4-二氯-3-烷基-6-硝基苯酚的制备方法是在催化剂存在下用氯氯化具有C 2 -C 8烷基的1-烷基-4-硝基苯，直到三氯烷基硝基苯的含量至少为 在氯化混合物中为60重量％，从氯化混合物中除去催化剂，然后水解氯化混合物，除去沉淀的反应产物，并用无机酸水溶液处理。 2,4-二氯-3-烷基-6-硝基苯酚是新的。

公开(公告)号：US4668615A

公开(公告)日：1987-05-26

申请号：US767981

申请日：1985-08-21

Applicant: Ken Kawata ,  Yoshiharu Yabuki ,  Kozo Sato ,  Hiroyuki Hirai

Inventor： Ken Kawata ,  Yoshiharu Yabuki ,  Kozo Sato ,  Hiroyuki Hirai

IPC: G03C8/40 ,  C07C51/00 ,  C07C57/30 ,  C07C61/39 ,  C07C62/32 ,  C07C67/00 ,  C07C201/00 ,  C07C205/56 ,  C07C239/00 ,  C07C279/02 ,  C07C313/00 ,  C07C317/44 ,  C07D213/55 ,  C07D215/12 ,  C07D215/14 ,  C07D263/56 ,  G03C1/06 ,  G03C1/498 ,  G03C7/00 ,  G03C1/40 ,  G03C5/54

CPC classification number: C07C61/39 ,  C07C205/56 ,  C07C57/30 ,  C07C62/32 ,  G03C1/49845 ,  Y10S430/156

Abstract: A heat developable light-sensitive material containing a compound represented by the general formula (I):[Ar.sub.n (R).sub.3-n CCO.sub.2 H].sub.l .multidot.B.sub.m (I)wherein ar represents an aryl group or a heterocyclic group; R represents a substituent other than an aryl group and a heterocyclic group; Ar and R may be bonded in a part thereof to form a ring; B represents a mono- or diacidic base which has a pKa of 7 or more and contains 12 or less carbon atoms; n represents an integer from 1 to 3; l and m each represents an integer of 1 or 2 and maintain a relationship in that a number of positive charge and a number of negative charge are equal; when n represents 1 or 2, two R's or Ar's may be the same or different, when n represents 3, three Ar's may be the same or different; and the substituent represented by Ar or R may be further substituted with a substituent. The compound represented by the general formula (I) is a base precursor which is stable at normal temperature but rapidly decomposes to release a base by heating and therefore the heat developable light-sensitive material containing the base precursor has excellent preservability and provides images having good image quality, i.e., low fog density and high image density upon a short period of developing time.

Abstract translation: 含有通式（I）表示的化合物的热显影性感光材料：[Arn（R）3-nCCO2H] lxBm（I）其中ar表示芳基或杂环基; R表示除芳基和杂环基以外的取代基; Ar和R可以部分结合形成环; B表示pKa为7以上且含有12个以下碳原子的单或二酸碱基; n表示1〜3的整数， l和m各自表示1或2的整数，并且保持正电荷数和负电荷数相等的关系; 当n表示1或2时，两个R或Ar可以相同或不同，当n表示3时，三个Ar可以相同或不同; 并且由Ar或R表示的取代基可以进一步被取代基取代。 由通式（I）表示的化合物是在常温下稳定但快速分解以通过加热而释放碱的基础前体，因此含有碱性前体的可热显影的感光材料具有优异的保存性并提供具有良好的图像 图像质量，即在较短的显影时间内的低雾密度和高图像密度。

公开(公告)号：US4626607A

公开(公告)日：1986-12-02

申请号：US695047

申请日：1985-01-25

Applicant: Bernard Jacquinot ,  Jacques Quibel ,  Roger Mari

Inventor： Bernard Jacquinot ,  Jacques Quibel ,  Roger Mari

IPC: C07C1/00 ,  C07C67/00 ,  C07C201/00 ,  C07C201/08 ,  C07C205/02 ,  C07C79/04

CPC classification number: C07C201/08

Abstract: The invention concerns the manufacture of nitromethane by nitration of mene in a homogeneous gaseous phase, the nitrating agent being nitric acid, nitrogen peroxide or mixtures thereof. According to the disclosed process, the molar ratio methane/nitrating agent is between 0.1 and 5; the reaction contact time between 0.1 and 120 seconds; the reaction pressure between 1 and 35 bars; the temperature between 270.degree. and 600.degree. C. The nitration is carried out in the presence of an active agent of the halogen or derivative type introduced in a molar ratio at the most equal to 3. An installation is disclosed for industrially manufacturing nitromethane.

Abstract translation: 本发明涉及通过在均相气相中硝化甲烷来制造硝基甲烷，硝化剂是硝酸，过氧化氮或其混合物。 根据所公开的方法，甲烷/硝化剂的摩尔比在0.1和5之间; 反应接触时间在0.1〜120秒之间; 反应压力在1至35巴之间; 温度在270℃至600℃之间。硝化在以等于3的摩尔比引入的卤素或衍生物类型的活性剂存在下进行。在工业上制造硝基甲烷的设备被公开。

公开(公告)号：US4608435A

公开(公告)日：1986-08-26

申请号：US489360

申请日：1983-04-28

Applicant: Frederick H. Howell

Inventor： Frederick H. Howell

IPC: C07C50/24 ,  C07C45/00 ,  C07C46/06 ,  C07C50/26 ,  C07C50/28 ,  C07C50/38 ,  C07C51/00 ,  C07C51/16 ,  C07C51/29 ,  C07C59/52 ,  C07C66/00 ,  C07C67/00 ,  C07C69/757 ,  C07C201/00 ,  C07C205/45 ,  C07C213/00 ,  C07C225/28 ,  C07C231/00 ,  C07C235/78 ,  C07C253/00 ,  C07C255/31 ,  C07C317/24 ,  C07F9/30 ,  C07F9/40 ,  G03C7/02 ,  G03C7/28 ,  C07C50/00 ,  C07D265/32 ,  C07D413/00

CPC classification number: G03C7/28 ,  C07C46/06 ,  C07C50/28 ,  C07C51/16 ,  C07C51/29 ,  C07C59/52 ,  C07C66/00 ,  C07F9/4018

Abstract: New benzo-1,4-quinones and salts thereof with organic or inorganic acid and bases have the formula I ##STR1## wherein p is 1 or 2 and q is 0 or 1, provided that p+q is 1 or 2, R is a residue of formula II ##STR2## wherein Q is selected from the residues --CO.sub.2 R.sub.4, --CON(R.sub.4)(R.sub.5), --OR.sub.5, --OCOR.sub.7, --N(R.sub.8)(R.sub.9), --PO(OR.sub.10)([O].sub.x R.sub.11), --SO.sub.2 R.sub.12, --CN, Halogen, --NO.sub.2 or --COR.sub.13, n is an integer from 1 to 20, k is 1 or 2 and x is 0 or 1, and R.sub.1 to R.sub.5 and R.sub.7 to R.sub.13 are as defined in the specification.The compounds of formula I are useful in photographic materials such as bleaching inhibitors in films of photographic silver dye bleach materials.

Abstract translation: 新的苯并-1,4-醌及其与有机或无机酸和碱的盐具有式I（I）其中p为1或2，q为0或1，条件是p + q为1或2 R为残基-CO 2 R 4，-CON（R 4）（R 5），-OR 5，-OCOR 7，-N（R 8）（R 9），-PO （OR 10）（[O] x R 11），-SO 2 R 12，-CN，卤素，-NO 2或-COR 13，n为1至20的整数，k为1或2，x为0或1，R1至R5和 R7至R13如说明书中所定义。 式I化合物可用于照相材料，如照相银染料漂白材料的薄膜中的漂白抑制剂。

公开(公告)号：US4596885A

公开(公告)日：1986-06-24

申请号：US875707

申请日：1978-02-06

Applicant: Winfried Lunkenheimer ,  Andreas Wittig ,  Wilfried Draber ,  Helmut Timmler

Inventor： Winfried Lunkenheimer ,  Andreas Wittig ,  Wilfried Draber ,  Helmut Timmler

IPC: C07C69/716 ,  C07C67/00 ,  C07C69/738 ,  C07C201/00 ,  C07C205/56 ,  C07D253/06 ,  C07D253/07 ,  C07C69/76

CPC classification number: C07D253/06 ,  C07D253/07

Abstract: A process for the preparation of a phenylglyocylic acid ester of the formula ##STR1## wherein R.sup.1 represents alkyl,X represents halogen, alkyl, halogenoalkyl, alkoxy or nitro, andn represents 0, 1, 2, or 3by contacting a benzoyl cyanide of the formula ##STR2## wherein X and n have the meanings stated above, in a sulphuric acid/water system in the presence of chloride ions at a temperature between 0.degree. and 70.degree. C. to form phenylglyoxylic acid amide and reacting the phenylglyoxylic acid amide without isolation with an alcohol of the formula R.sup.1 -OH, wherein R.sup.1 has the meaning stated above, optionally in the presence of a diluent, at a temperature between 40.degree. and 100.degree. C.

Abstract translation: 制备式（Ⅶ）的苯基乙二酸酯的方法，其中R 1表示烷基，X表示卤素，烷基，卤代烷基，烷氧基或硝基，n表示0,1,2或3， 在硫酸/水体系中，在氯离子存在下，在0〜70℃的温度下，式（ⅩⅧ）的苯甲酰氰（其中X和n具有上述含义），形成苯基乙醛酸酰胺 并且使苯基乙醛酸酰胺与分子式为R 1 -OH的醇反应，其中R 1具有上述含义，任选在稀释剂存在下，在40℃至100℃的温度下反应。