公开(公告)号：US10527528B2

公开(公告)日：2020-01-07

申请号：US16164343

申请日：2018-10-18

Applicant: APPLIKATE TECHNOLOGIES LLC

Inventor： Michael Levene ,  Richard Torres

IPC: G01N1/00 ,  G01N1/36 ,  G01N1/30 ,  G06T7/00 ,  C12M1/12

Abstract: The present invention relates to systems and methods for tissue processing and analysis. Tissue chambers are configured to allow single-container chemical processing, imaging, and wax embedding of tissue samples in a single container without manipulation between steps. Tissue chambers with features to support the tissue sample and allow fluid flow between the tissue sample and the tissue chamber surface are disclosed. The features may be index matched to sample structures of interest or dissolvable in clearing solution to allow for in-chamber imaging with minimal distortion. Specialized tissue processing and wax removal apparatuses are also disclosed including for use with tissue chambers having frangible portions to permit ease of wax removal.